Publications by authors named "Rainer Spang"

100Publications

DTD: An R Package for Digital Tissue Deconvolution.

J Comput Biol 2020 03 29;27(3):386-389. Epub 2020 Jan 29.

Department of Statistical Bioinformatics, Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1089/cmb.2019.0469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074920PMC
March 2020

Loss-Function Learning for Digital Tissue Deconvolution.

J Comput Biol 2020 03 29;27(3):342-355. Epub 2020 Jan 29.

Department of Statistical Bioinformatics, Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1089/cmb.2019.0462DOI Listing
March 2020

Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach.

Biol Proced Online 2019 1;21:13. Epub 2019 Jul 1.

Department of Pathology, Hematopathology Section and Lymph Node Registry, University of Kiel/University Hospital Schleswig-Holstein, Arnold-Heller-Str. 3, Haus 14, Kiel, 24105 Germany.

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http://dx.doi.org/10.1186/s12575-019-0098-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600891PMC
July 2019

Modelling cancer progression using Mutual Hazard Networks.

Bioinformatics 2020 01;36(1):241-249

Department of Statistical Bioinformatics, Institute of Functional Genomics, Regensburg 93040, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btz513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956791PMC
January 2020

Random gene sets in predicting survival of patients with hepatocellular carcinoma.

J Mol Med (Berl) 2019 06 17;97(6):879-888. Epub 2019 Apr 17.

Division of Hepatology & Division of Clinical Bioinformatics, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

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http://dx.doi.org/10.1007/s00109-019-01764-2DOI Listing
June 2019

Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma.

BMC Cancer 2019 Apr 5;19(1):322. Epub 2019 Apr 5.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, D-10117, Berlin, Germany.

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http://dx.doi.org/10.1186/s12885-019-5537-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451309PMC
April 2019

A Novel Metabolic Signature To Predict the Requirement of Dialysis or Renal Transplantation in Patients with Chronic Kidney Disease.

J Proteome Res 2019 04 12;18(4):1796-1805. Epub 2019 Mar 12.

Institute of Genetic Epidemiology, Department of Biometry, Epidemiology, and Medical Bioinformatics, Faculty of Medicine and Medical Center , University of Freiburg , Freiburg 79106 , Germany.

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http://dx.doi.org/10.1021/acs.jproteome.8b00983DOI Listing
April 2019

Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma-a feasibility study using full slide staining.

Virchows Arch 2018 Sep 5;473(3):341-349. Epub 2018 May 5.

Department of Pathology, Hematopathology Section, University Hospital Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, D-24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s00428-018-2367-4DOI Listing
September 2018

Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints.

J Proteome Res 2017 10 7;16(10):3596-3605. Epub 2017 Sep 7.

Department of Physics, University of Regensburg , Universitätsstraße 31, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.7b00325DOI Listing
October 2017

Spindle-Cell Variants of Primary Cutaneous Follicle Center B-Cell Lymphomas Are Germinal Center B-Cell Lymphomas by Gene Expression Profiling Using a Formalin-Fixed Paraffin-Embedded Specimen.

J Invest Dermatol 2017 11 3;137(11):2450-2453. Epub 2017 Jul 3.

Department of Pathology, Hematopathology Section and Lymph Node Registry, Christian-Albrechts-University of Kiel, University-Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X173177
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http://dx.doi.org/10.1016/j.jid.2017.06.016DOI Listing
November 2017

Cell-of-origin classification by gene expression and MYC-rearrangements in diffuse large B-cell lymphoma of children and adolescents.

Br J Haematol 2017 10 23;179(1):116-119. Epub 2017 Jun 23.

Department of Pathology, Haematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel/Christian-Albrecht University, Kiel, Germany.

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http://dx.doi.org/10.1111/bjh.14812DOI Listing
October 2017

External calibration with Drosophila whole-cell spike-ins delivers absolute mRNA fold changes from human RNA-Seq and qPCR data.

Biotechniques 2017 02 1;62(2):53-61. Epub 2017 Feb 1.

Statistical Bioinformatics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.2144/000114514DOI Listing
February 2017

High-Dimensional Profiling for Computational Diagnosis.

Methods Mol Biol 2017 ;1526:205-229

Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-6613-4_12DOI Listing
January 2018

Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis.

Int J Cancer 2017 Mar 17;140(5):1147-1158. Epub 2016 Oct 17.

Clinic of Haematology and Medical Oncology, University Medical Centre of the Georg-August University Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1002/ijc.30444DOI Listing
March 2017

Adjusting microbiome profiles for differences in microbial load by spike-in bacteria.

Microbiome 2016 06 21;4(1):28. Epub 2016 Jun 21.

Chair of Statistical Bioinformatics, University of Regensburg, Am BioPark 9, 93053, Regensburg, Germany.

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http://dx.doi.org/10.1186/s40168-016-0175-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915049PMC
June 2016

Refining Pathways: A Model Comparison Approach.

PLoS One 2016 1;11(6):e0155999. Epub 2016 Jun 1.

Department of Statistical Bioinformatics, Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155999PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889067PMC
July 2017

Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models.

Bioinformatics 2016 03 17;32(6):893-900. Epub 2015 Nov 17.

Statistical Bioinformatics Department, Institute of Functional Genomics, University of Regensburg, 93053 Regensburg and.

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http://dx.doi.org/10.1093/bioinformatics/btv680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939970PMC
March 2016

A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA).

Bioinformatics 2015 Dec 6;31(23):3807-14. Epub 2015 Aug 6.

Department of Statistical Bioinformatics, University of Regensburg, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btv461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653390PMC
December 2015

Clinical and pathological features of Burkitt lymphoma showing expression of BCL2--an analysis including gene expression in formalin-fixed paraffin-embedded tissue.

Br J Haematol 2015 Nov 27;171(4):501-8. Epub 2015 Jul 27.

Department of Pathology, Haematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel/Christian-Albrecht University, Kiel, Germany.

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http://doi.wiley.com/10.1111/bjh.13624
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http://dx.doi.org/10.1111/bjh.13624DOI Listing
November 2015

Data Normalization of (1)H NMR Metabolite Fingerprinting Data Sets in the Presence of Unbalanced Metabolite Regulation.

J Proteome Res 2015 Aug 22;14(8):3217-28. Epub 2015 Jul 22.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str. 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.5b00192DOI Listing
August 2015

siPools: highly complex but accurately defined siRNA pools eliminate off-target effects.

Nucleic Acids Res 2014 Jul 29;42(12):8049-61. Epub 2014 May 29.

Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gku480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081087PMC
July 2014

Increased expression of c-Jun in nonalcoholic fatty liver disease.

Lab Invest 2014 Apr 3;94(4):394-408. Epub 2014 Feb 3.

Department of Internal Medicine I, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/labinvest.2014.3DOI Listing
April 2014

YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis.

PLoS One 2013 12;8(12):e82166. Epub 2013 Dec 12.

Institute of Pathology, University of Regensburg, Regensburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082166PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861381PMC
October 2014

Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction.

Bioinformatics 2014 Feb 30;30(3):414-9. Epub 2013 Nov 30.

Institute for Genetics, University of Cologne, 50674 Cologne, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Gene Center, Department of Biochemistry, Ludwig-Maximilians University, 81379 Munich, Germany, Insitute for Functional Genomics, 93053 Regensburg, Germany, Department of Radiology, Center for Cancer Systems Biology, Stanford University, Stanford, CA 94305-5488, USA and ETH Zürich, Department of Biosystems Science and Engineering, Mattenstrasse 26 4058 Basel, Switzerland.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btt696DOI Listing
February 2014

Considering unknown unknowns: reconstruction of nonconfoundable causal relations in biological networks.

J Comput Biol 2013 Nov;20(11):920-32

Institute of Functional Genomics, Computational Diagnostics Group, University of Regensburg , Regensburg, Germany .

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http://dx.doi.org/10.1089/cmb.2013.0119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822397PMC
November 2013

Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.

Nat Commun 2013 ;4:2610

1] German Cancer Research Center (DKFZ), Div. Signalling and Functional Genomics, and Heidelberg University, Dept. Cell and Molecular Biology, Faculty of Medicine Mannheim, Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany [2].

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http://dx.doi.org/10.1038/ncomms3610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826636PMC
June 2014

Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens.

Blood 2013 Sep;122(11):1985-6

Department of Pathology, Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel/Christian-Albrecht University, Kiel, Germany.

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http://dx.doi.org/10.1182/blood-2013-06-508937DOI Listing
September 2013

Melanoma inhibitory activity promotes melanoma development through activation of YBX1.

Pigment Cell Melanoma Res 2013 Sep 14;26(5):685-96. Epub 2013 Jun 14.

Institute of Pathology, University of Regensburg Medical School, Regensburg, Germany.

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http://dx.doi.org/10.1111/pcmr.12119DOI Listing
September 2013

Aberrant lymphocyte enhancer-binding factor 1 expression is characteristic for sporadic Burkitt's lymphoma.

Am J Pathol 2013 Apr 31;182(4):1092-8. Epub 2013 Jan 31.

Department of Hematology and Oncology, University Medical Centre of the Georg-August University of Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1016/j.ajpath.2012.12.013DOI Listing
April 2013

Performance evaluation of algorithms for the classification of metabolic 1H NMR fingerprints.

J Proteome Res 2012 Dec 12;11(12):6242-51. Epub 2012 Nov 12.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1021/pr3009034DOI Listing
December 2012

T cells become licensed in the lung to enter the central nervous system.

Nature 2012 Aug;488(7413):675-9

Institute for Multiple Sclerosis Research, Department of Neuroimmunology, Gemeinnützige Hertie-Stiftung and University Medical Centre Göttingen, 37073 Göttingen, Germany.

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http://dx.doi.org/10.1038/nature11337DOI Listing
August 2012

A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions.

PLoS One 2012 17;7(7):e40634. Epub 2012 Jul 17.

Department of Statistical Bioinformatics, Institute for Functional Genomics, University of Regensburg, Regensburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040634PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398908PMC
March 2013

State-of-the art data normalization methods improve NMR-based metabolomic analysis.

Metabolomics 2012 Jun 12;8(Suppl 1):146-160. Epub 2011 Aug 12.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1007/s11306-011-0350-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337420PMC
June 2012

Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma.

Blood 2012 Feb 11;119(8):1882-7. Epub 2012 Jan 11.

Department of Pathology, Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel/University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1182/blood-2011-10-388470DOI Listing
February 2012

High Myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas.

Int J Cancer 2012 Aug 23;131(4):E348-61. Epub 2011 Oct 23.

Department of Haematology and Oncology, University Medical Centre of the Georg-August University Göttingen, Germany.

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http://dx.doi.org/10.1002/ijc.26423DOI Listing
August 2012

Estimating classification probabilities in high-dimensional diagnostic studies.

Bioinformatics 2011 Sep 22;27(18):2563-70. Epub 2011 Jul 22.

Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btr434DOI Listing
September 2011

Genomic data integration using guided clustering.

Bioinformatics 2011 Aug 17;27(16):2231-8. Epub 2011 Jun 17.

Institut für funktionelle Genomik, Universität Regensburg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btr363DOI Listing
August 2011

Transcriptome asymmetry within mouse zygotes but not between early embryonic sister blastomeres.

EMBO J 2011 May 5;30(9):1841-51. Epub 2011 Apr 5.

Laboratory of Mammalian Molecular Embryology, RIKEN Center for Developmental Biology, Kobe, Japan.

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http://dx.doi.org/10.1038/emboj.2011.92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101998PMC
May 2011

ReseqChip: automated integration of multiple local context probe data from the MitoChip array in mitochondrial DNA sequence assembly.

BMC Bioinformatics 2009 Dec 22;10:440. Epub 2009 Dec 22.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Str, 9, D-93053 Regensburg, Germany.

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http://dx.doi.org/10.1186/1471-2105-10-440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087351PMC
December 2009

Kinetic laws, phase-phase expansions, renormalization group, and INR calibration.

Proc Natl Acad Sci U S A 2009 Apr 6;106(16):6465-70. Epub 2009 Apr 6.

Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA.

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http://dx.doi.org/10.1073/pnas.0809855106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672524PMC
April 2009

Modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models.

Proc Natl Acad Sci U S A 2009 Apr 27;106(16):6447-52. Epub 2009 Mar 27.

Institute of Functional Genomics, University of Regensburg, Josef-Engert-Strasse 9, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1073/pnas.0809822106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672479PMC
April 2009

Analyzing gene perturbation screens with nested effects models in R and bioconductor.

Bioinformatics 2008 Nov 21;24(21):2549-50. Epub 2008 Aug 21.

German Cancer Research Center, INF 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btn446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732276PMC
November 2008

Computational diagnostics with gene expression profiles.

Methods Mol Biol 2008 ;453:281-96

Max Planck Institute for Molecular Genetics and Berlin Center for Genome-Based Bioinformatics, Berlin, Germany.

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http://dx.doi.org/10.1007/978-1-60327-429-6_15DOI Listing
October 2008

Detecting hierarchical structure in molecular characteristics of disease using transitive approximations of directed graphs.

Bioinformatics 2008 Apr 19;24(7):995-1001. Epub 2008 Feb 19.

Computational Diagnostics Group, Institute of Functional Genomics, University of Regensburg, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btn056DOI Listing
April 2008

Microarray based diagnosis profits from better documentation of gene expression signatures.

PLoS Comput Biol 2008 Feb;4(2):e22

Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1371/journal.pcbi.0040022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242819PMC
February 2008

CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells.

Am J Pathol 2008 Feb 10;172(2):510-20. Epub 2008 Jan 10.

Charité-University Medicine Berlin, Campus Benjamin Franklin, Institute of Pathology, D-12200 Berlin, Germany.

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http://dx.doi.org/10.2353/ajpath.2008.070858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312360PMC
February 2008

Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma.

Cancer Epidemiol Biomarkers Prev 2007 Nov;16(11):2486-90

Department of Dermatology, Regensburg University Medical Center, Franz-Josef Strauss-Allee 11, D-93053 Regensburg, Germany.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0224DOI Listing
November 2007

Inferring cellular networks--a review.

BMC Bioinformatics 2007 Sep 27;8 Suppl 6:S5. Epub 2007 Sep 27.

Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1186/1471-2105-8-S6-S5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995541PMC
September 2007

Compensating for unknown confounders in microarray data analysis using filtered permutations.

J Comput Biol 2007 Jun;14(5):669-81

Max Planck Institute for Molecular Genetics, Computational Diagnostics Group, Berlin, Germany.

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http://dx.doi.org/10.1089/cmb.2007.R009DOI Listing
June 2007

Nested effects models for high-dimensional phenotyping screens.

Bioinformatics 2007 Jul;23(13):i305-12

Lewis-Sigler Institute for Integrative Genomics and Department of Computer Science, Princeton University, Princeton, NJ, 08544, USA.

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http://dx.doi.org/10.1093/bioinformatics/btm178DOI Listing
July 2007

Annotation-based distance measures for patient subgroup discovery in clinical microarray studies.

Bioinformatics 2007 Sep 22;23(17):2256-64. Epub 2007 Jun 22.

Max Planck Institute for Molecular Genetics and Berlin Center for Genome Based Bioinformatics, Ihnestr. 73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btm322DOI Listing
September 2007

Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues.

Clin Cancer Res 2007 Feb;13(3):806-15

Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-06-1820DOI Listing
February 2007

A stochastic downhill search algorithm for estimating the local false discovery rate.

IEEE/ACM Trans Comput Biol Bioinform 2004 Jul-Sep;1(3):98-108

Max Planck Institute for Molecular Genetics, Computational Diagnostics, Berlin, Germany.

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http://dx.doi.org/10.1109/TCBB.2004.24DOI Listing
November 2006

Similarities of ordered gene lists.

J Bioinform Comput Biol 2006 Jun;4(3):693-708

Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1142/s0219720006002120DOI Listing
June 2006

Selecting normalization genes for small diagnostic microarrays.

BMC Bioinformatics 2006 Aug 22;7:388. Epub 2006 Aug 22.

Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany.

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http://dx.doi.org/10.1186/1471-2105-7-388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560169PMC
August 2006

Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia.

Clin Cancer Res 2006 Aug;12(15):4553-61

Department of Pediatric Oncology/Hematology, HELIOS Klinikum Berlin, Robert-Roessle-Clinic, Laboratory for Functional Genomics, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0235DOI Listing
August 2006

OrderedList--a bioconductor package for detecting similarity in ordered gene lists.

Bioinformatics 2006 Sep 14;22(18):2315-6. Epub 2006 Jul 14.

Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics Ihnestrasse 63-73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btl385DOI Listing
September 2006

Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring.

BMC Bioinformatics 2006 Jun 5;7:282. Epub 2006 Jun 5.

Max Planck Institute for Molecular Genetics & Berlin Center for Genome Based Bioinformatics, Ihnestrasse, 73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.1186/1471-2105-7-282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501051PMC
June 2006

Early diagnostic marker panel determination for microarray based clinical studies.

Stat Appl Genet Mol Biol 2005 26;4:Article9. Epub 2005 Apr 26.

Max Planck Institute for Molecular Genetics, Berlin.

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http://dx.doi.org/10.2202/1544-6115.1109DOI Listing
May 2006