Publications by authors named "Rainer Grobholz"

84Publications

Current opinion, status and future development of digital pathology in Switzerland.

J Clin Pathol 2020 Jun 19;73(6):341-346. Epub 2019 Dec 19.

Institute of Pathology, University of Bern, Bern, Switzerland

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http://dx.doi.org/10.1136/jclinpath-2019-206155DOI Listing
June 2020

Prostatakarzinom – von der konventionellen zur molekularen Diagnostik.

Authors:
Rainer Grobholz

Ther Umsch 2017 Sep;74(4):165-170

1 Medizinische Fakultät Universität Zürich, Zürich.

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http://dx.doi.org/10.1024/0040-5930/a000900DOI Listing
September 2017

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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http://www.cell.com/cell/pdf/S0092-8674(16)00055-6.pdf
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http://www.cell.com/cms/attachment/2048488015/2058390163/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741600055
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http://dx.doi.org/10.1016/j.cell.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139621PMC
February 2016

Urothelial Cancer in Renal Transplant Recipients: Incidence, Risk Factors, and Oncological Outcome.

Urology 2016 Feb 8;88:104-10. Epub 2015 Dec 8.

Department of Transplant Immunology & Nephrology, University Hospital Basel, Switzerland.

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http://dx.doi.org/10.1016/j.urology.2015.10.031DOI Listing
February 2016

Clear cell papillary renal cell carcinoma and renal angiomyoadenomatous tumor: two variants of a morphologic, immunohistochemical, and genetic distinct entity of renal cell carcinoma.

Am J Surg Pathol 2015 Jul;39(7):889-901

*Institute of Surgical Pathology, University Hospital Zurich, Zurich ‡‡Cantonal Hospital Aarau §§Institute of Histological and Cytological Diagnostics, Aarau ¶¶University Institute of Pathology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland †Institute of Pathology, University Medicine Göttingen (UMG), Göttingen ∥Institute of Pathology, University Hospital Tübingen, Tübingen ¶Institute of Pathology, HELIOS Hospital Berlin-Buch, Berlin #Institute of Pathology Bogenhausen, Städtisches Klinikum München GmbH, Munich **Institute of Pathology, Heinrich Heine University Hospital, Dusseldorf ††Institute of Pathology, RWTH University, Aachen ∥∥Institute of Pathology, HELIOS Hospital Schwerin, Schwerin ***Institute of Pathology, Städtisches Klinikum Karlsruhe gGmbH, Karlsruhe †††Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany ‡Service d'Anatomie et Cytologie Pathologiques 1, Groupe Hospitalier Pitié-Salpêtrière, Paris, France §Department of Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA ##Institute of Pathology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1097/PAS.0000000000000456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465996PMC
July 2015

Pulmonary tularaemia: all that looks like cancer is not necessarily cancer - case report of four consecutive cases.

BMC Pulm Med 2015 Mar 26;15:27. Epub 2015 Mar 26.

Clinic of Pulmonary and Sleep Medicine, Cantonal Hospital Aarau, Tellstrasse, CH-5001, Aarau, Switzerland.

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http://dx.doi.org/10.1186/s12890-015-0026-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386093PMC
March 2015

A "PSA pyramid" for men with initial prostate-specific antigen ≤3 ng/ml: a plea for individualized prostate cancer screening.

Eur Urol 2015 Oct 18;68(4):591-7. Epub 2014 Apr 18.

Department of Urology, Cantonal Hospital Aarau, Aarau, Switzerland; Department of Urology, Academic Hospital Braunschweig, Braunschweig, Germany.

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http://dx.doi.org/10.1016/j.eururo.2014.04.005DOI Listing
October 2015

Differentiation between calcification and hemorrhage in brain tumors using susceptibility-weighted imaging: a pilot study.

AJR Am J Roentgenol 2014 Apr;202(4):847-50

1 Department of Radiology, Cantonal Hospital Aarau, Tellstrasse, CH-5001 Aarau, Switzerland.

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http://dx.doi.org/10.2214/AJR.13.10745DOI Listing
April 2014

Margin status of the vas deferens in radical prostatectomy specimens: relevant or waste of time?

Histopathology 2014 Jul 24;65(1):45-50. Epub 2014 Mar 24.

Department of Urology and Pediatric Urology, Saarland University Medical Center, Homburg/Saar, Germany.

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http://dx.doi.org/10.1111/his.12369DOI Listing
July 2014

Collecting duct carcinomas represent a unique tumor entity based on genetic alterations.

PLoS One 2013 22;8(10):e78137. Epub 2013 Oct 22.

Department of Urology, University of the Saarland, Homburg/Saar, Germany ; Urological Group Practice & Clinic Derouet/Pönicke/Becker, Boxberg Center, Neunkirchen, Germany ; for the German Network of Renal Cell Tumors, Jena, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078137PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805592PMC
May 2014

Multiple complicated gallbladder disease.

J Gastrointestin Liver Dis 2011 03;20(1):98-9

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March 2011

Yeast-based identification of prostate tumor antigens provides an effective vaccine platform.

Anticancer Res 2010 Mar;30(3):895-902

University Hospital Zurich, Department of Oncology, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

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March 2010

TRPV6 alleles do not influence prostate cancer progression.

BMC Cancer 2009 Oct 26;9:380. Epub 2009 Oct 26.

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, Homburg/Saar, Germany.

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http://dx.doi.org/10.1186/1471-2407-9-380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774862PMC
October 2009

Investigation of the thermal tissue effects of the argon plasma coagulation modes "pulsed" and "precise" on the porcine esophagus, ex vivo and in vivo.

Gastrointest Endosc 2009 Aug 5;70(2):362-8. Epub 2009 Jun 5.

Section Endoscopy, Surgical University Hospital Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.gie.2008.11.050DOI Listing
August 2009

Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy.

J Cancer Res Clin Oncol 2009 Sep 10;135(9):1239-44. Epub 2009 Mar 10.

Department of Neurosurgery, Universitätsmedizin Mannheim, University of Heidelberg, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1007/s00432-009-0565-9DOI Listing
September 2009

Clinical staging error in prostate cancer: localization and relevance of undetected tumour areas.

BJU Int 2009 May 22;103(9):1184-9. Epub 2009 Dec 22.

Department of Urology, Mannheim Medical Center, University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1111/j.1464-410X.2008.08243.xDOI Listing
May 2009

Serum vascular endothelial growth factor C level in patients with prostate cancer and benign prostatic hyperplasia.

Anal Quant Cytol Histol 2008 Aug;30(4):199-202

Department of Urology, University Hospital Mannheim, Mannheim, Germany.

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August 2008

Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer.

Cancer 2007 Oct;110(8):1697-707

Department of Experimental Surgery Mannheim/Molecular Oncology of Solid Tumors, Deutsches Krebsforschungszentrum and University Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1002/cncr.22983DOI Listing
October 2007

Novel germ cell markers characterize testicular seminoma and fetal testis.

Mol Hum Reprod 2007 Oct 4;13(10):721-7. Epub 2007 Sep 4.

Institute of Anatomy, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1093/molehr/gam059DOI Listing
October 2007

A new electromagnetic shock-wave generator "SLX-F2" with user-selectable dual focus size: ex vivo evaluation of renal injury.

Urol Res 2007 Aug 5;35(4):165-71. Epub 2007 May 5.

Department of Urology, University Hospital Mannheim, Faculty of Clinical Medicine Mannheim, Ruprecht-Karls-University Heidelberg, Theodor-Kutzer-Ufer 1-3, 68135 Mannheim, Germany.

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http://dx.doi.org/10.1007/s00240-007-0097-1DOI Listing
August 2007

Endoscopic full-thickness gastric resection using a flexible stapler device.

Surg Technol Int 2007 ;16:61-5

University Hospital Mannheim, University of Heidelberg, Manheim, Germany.

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January 2010

Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer.

Int J Radiat Oncol Biol Phys 2006 Dec 18;66(5):1384-90. Epub 2006 Sep 18.

Onkologisches Zentrum, III, Medizinische Klinik, Fakultät für Klinische Medizin Mannheim der Universität Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2006.07.005DOI Listing
December 2006

Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.

Oncol Rep 2006 Oct;16(4):657-61

Department of Surgery, University Hospital Mannheim, 68135 Mannheim, Germany.

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October 2006

The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation.

Int J Cancer 2006 Nov;119(10):2287-93

Department of Dermatology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1002/ijc.22106DOI Listing
November 2006

Urothelial carcinoma of the ureter, giant rectal stone and sigmoid carcinoma 55 years after ureterosigmoidostomy.

Scand J Urol Nephrol 2006 ;40(2):172-3

Department of Surgery, University Hospital Mannheim, Ruprecht-Karls-University Heidelberg, Mannheim, Germany.

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http://www.tandfonline.com/doi/full/10.1080/0036559060068841
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http://dx.doi.org/10.1080/00365590600688419DOI Listing
October 2006

EphB4 controls blood vascular morphogenesis during postnatal angiogenesis.

EMBO J 2006 Feb 19;25(3):628-41. Epub 2006 Jan 19.

Department of Neurosurgery, Faculty for Clinical Medicine of the University of Heidelberg, University Hospital Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7600949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383533PMC
February 2006

IGF-II serum levels increase discrimination between benign prostatic hyperplasia and prostate cancer and improve the predictive value of PSA in clinical staging.

Eur Urol 2006 Feb 7;49(2):286-92; discussion 292. Epub 2005 Dec 7.

Department of Urology, University Hospital Mannheim, Heidelberg University, Germany.

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http://dx.doi.org/10.1016/j.eururo.2005.08.022DOI Listing
February 2006

Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade.

Hum Pathol 2005 Nov 7;36(11):1186-96. Epub 2005 Oct 7.

Hormones and Signal Transduction Group, German Cancer Research Centre, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.humpath.2005.07.023DOI Listing
November 2005

Genetic analysis of neuroendocrine tumor cells in prostatic carcinoma.

Prostate 2006 Feb;66(3):227-34

Department of Pathology, University Hospital Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1002/pros.20338DOI Listing
February 2006

Minimally invasive treatment of renal cell carcinoma: comparison of 4 different monopolar radiofrequency devices.

Eur Urol 2005 Oct;48(4):584-92

Department of Urology, University Hospital Mannheim, Faculty of Clinical Medicine Mannheim, Ruprecht-Karls University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.eururo.2005.06.010DOI Listing
October 2005

HIV-related and Epstein-Barr virus-associated anal Burkitt's lymphoma: report of a case.

Dis Colon Rectum 2005 Aug;48(8):1656-9

Department of Surgery, University Hospital Mannheim, Ruprecht-Karls-University , Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10350-005-0106-9DOI Listing
August 2005

Calcium-binding proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancer.

Clin Cancer Res 2005 Jul;11(14):5146-52

Research Group Hormones and Signal Transduction, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0352DOI Listing
July 2005

Influence of neuroendocrine tumor cells on proliferation in prostatic carcinoma.

Hum Pathol 2005 May;36(5):562-70

Department of Pathology, University Hospital Mannheim, Ruprecht-Karls-University Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.humpath.2005.02.019DOI Listing
May 2005

Standardization strategy for quantitative PCR in human seminoma and normal testis.

J Biotechnol 2005 May;117(2):163-71

Department of Pathology, University Hospital Mannheim, Ruprecht-Karls-University Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.jbiotec.2005.01.011DOI Listing
May 2005

Inflammatory regulation of extracellular matrix remodeling in calcific aortic valve stenosis.

Cardiovasc Pathol 2005 Mar-Apr;14(2):80-7

1st Department of Medicine (Cardiology, Angiology, Pneumology), Faculty of Clinical Medicine Mannheim, University of Heidelberg, Mannheim, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S105488070500006
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http://dx.doi.org/10.1016/j.carpath.2005.01.002DOI Listing
July 2005

Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme.

J Cancer Res Clin Oncol 2005 Jan 28;131(1):31-40. Epub 2004 Sep 28.

Department of Neurosurgery, Klinikum Mannheim, Medical Faculty, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1007/s00432-004-0620-5DOI Listing
January 2005

Expression of bone sialoprotein and bone morphogenetic protein-2 in calcific aortic stenosis.

J Heart Valve Dis 2004 Jul;13(4):560-6

1st Department of Medicine (Cardiology, Angiology, and Pneumology), University Hospital of Mannheim, Germany.

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July 2004

Expression of different vascular endothelial markers in prostate cancer and BPH tissue: an immunohistochemical and clinical evaluation.

Anticancer Res 2004 May-Jun;24(3a):1651-6

Department of Urology, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany.

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September 2004

Simple models improve the discrimination of prostate cancers from the peripheral gland by T1-weighted dynamic MRI.

Eur Radiol 2004 Oct 30;14(10):1793-801. Epub 2004 Jun 30.

Department of Medical Physics in Radiology, Deutsches Krebsforschungszentrum, INF 280, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00330-004-2386-1DOI Listing
October 2004

Reduction of PTEN and p27kip1 expression correlates with tumor grade in prostate cancer. Analysis in radical prostatectomy specimens and needle biopsies.

Virchows Arch 2004 Jun 29;444(6):509-17. Epub 2004 Apr 29.

Pathologisches Institut, Universitätsklinikum Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1007/s00428-004-1004-6DOI Listing
June 2004

Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulate aortic valve calcification.

J Mol Cell Cardiol 2004 Jan;36(1):57-66

First Department of Medicine (Cardiology, Angiology, and Pneumology), Faculty of Clinical Medicine Mannheim, University of Heidelberg, Theordor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2003.09.015DOI Listing
January 2004

Interleukin-1 beta promotes matrix metalloproteinase expression and cell proliferation in calcific aortic valve stenosis.

Atherosclerosis 2003 Oct;170(2):205-11

1st Department of Medicine (Cardiology, Angiology, and Pneumology), University Hospital of Mannheim, Mannheim, Germany.

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http://dx.doi.org/10.1016/s0021-9150(03)00284-3DOI Listing
October 2003

Can pre-operative contrast-enhanced dynamic MR imaging for prostate cancer predict microvessel density in prostatectomy specimens?

Eur Radiol 2004 Feb 3;14(2):309-17. Epub 2003 Oct 3.

Department of Oncological Diagnostics and Therapy, German Cancer Research Center, University Hospital Mannheim, Ruprecht Karls University, Heidelberg, Germany.

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https://www.europeanurology.com/article/S0302-2838(13)00513-
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http://www.em-consulte.com/en/article/855730
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http://link.springer.com/10.1007/s00330-003-2025-2
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http://dx.doi.org/10.1007/s00330-003-2025-2DOI Listing
February 2004

Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer.

Int J Cancer 2003 Nov;107(4):676-80

Research Group Hormones and Signal Transduction, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.11471DOI Listing
November 2003

Pathogenetic role of Chlamydia pneumoniae in calcific aortic stenosis: immunohistochemistry study and review of the literature.

J Heart Valve Dis 2003 Jul;12(4):447-53

1st Department of Medicine (Cardiology, Angiology, and Pneumology), University Hospital of Mannheim, University of Heidelberg, Germany.

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July 2003

High-resolution three-dimensional MR angiography of rodent tumors: morphologic characterization of intratumoral vasculature.

J Magn Reson Imaging 2003 Jul;18(1):59-65

Division Oncological Diagnostics and Therapy (E010), Research Program Radiological Diagnostics and Therapy, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/jmri.10318DOI Listing
July 2003

Bax, Bcl-2, fas and Fas-L antigen expression in human seminoma: correlation with the apoptotic index.

APMIS 2002 Oct;110(10):724-32

Department of Pathology, Ruprecht-Karls-University Heidelberg, University Hospital Mannheim, Germany.

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http://dx.doi.org/10.1034/j.1600-0463.2002.1101006.xDOI Listing
October 2002