Rainer Doffinger

Rainer Doffinger

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Rainer Doffinger

Rainer Doffinger

Publications by authors named "Rainer Doffinger"

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Anticytokine autoantibodies leading to infection: early recognition, diagnosis and treatment options.

Curr Opin Infect Dis 2019 Aug;32(4):330-336

Department of Clinical Biochemistry and Immunology, Addenbrookes Hospital.

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http://dx.doi.org/10.1097/QCO.0000000000000561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635052PMC
August 2019

A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway.

J Allergy Clin Immunol 2018 07 6;142(1):311-314.e6. Epub 2018 Mar 6.

Cancer Research UK Cambridge Institute, Cambridge, United Kingdom; Department of Clinical Immunology, Cambridge University Hospitals National Health Service Trust, Addenbrooke's Hospital, Cambridge, United Kingdom; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom; MRC Toxicology Unit, University of Leicester, Leicester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.01.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034011PMC
July 2018

Anticytokine autoantibodies in a patient with a heterozygous NFKB2 mutation.

J Allergy Clin Immunol 2018 04 7;141(4):1479-1482.e6. Epub 2017 Dec 7.

Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, United Kingdom; Department of Allergy, Asthma and Clinical Immunology, University Hospital Southampton, Southampton, United Kingdom; CRUK NIHR Experimental Cancer Medicine Centre, Southampton, United Kingdom; WISH Laboratory University Hospital Southampton NHS Foundation Trust, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2017.11.014DOI Listing
April 2018

BCG induced lupus vulgaris: an unexpected adverse event.

Arch Dis Child 2018 01 11;103(1):71-72. Epub 2017 Mar 11.

Department of Child and Adolescent Health, Mater Dei Hospital, Msida, Malta.

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http://dx.doi.org/10.1136/archdischild-2016-312338DOI Listing
January 2018

Glucose-6-Phosphatase Catalytic Subunit 3 () Deficiency Associated With Autoinflammatory Complications.

Front Immunol 2017 6;8:1485. Epub 2017 Nov 6.

Department of Clinical Immunology and Allergy, St James's University Hospital, Leeds, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2017.01485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681747PMC
November 2017

Autoimmune-autoinflammatory rheumatoid arthritis overlaps: a rare but potentially important subgroup of diseases.

RMD Open 2017 1;3(2):e000550. Epub 2017 Nov 1.

Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, St James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1136/rmdopen-2017-000550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687541PMC
November 2017

Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies.

PLoS One 2016 11;11(5):e0155059. Epub 2016 May 11.

Academic Unit of Cancer Sciences, Faculty of Medicine, University of Southampton and Southampton NIHR Experimental Cancer Medicine Centre, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155059PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864289PMC
July 2017

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

J Allergy Clin Immunol 2017 02 16;139(2):597-606.e4. Epub 2016 Jul 16.

Department of Paediatric Immunology, Newcastle upon Tyne hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2016.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292996PMC
February 2017

Anticytokine autoantibodies in infection and inflammation: an update.

Curr Opin Allergy Clin Immunol 2016 12;16(6):523-529

aLaboratorio 2 Inmunología, FES-Cuautitlán, UNAM, Mexico bService d' Allergologie et d'Immunologie, Hôpitaux Universitaires de Genève, Switzerland cDepartment of Clinical Biochemistry and Immunology, Addenbrookes Hospital dNational Institute of Health Research (NIHR), Cambridge Biomedical Reserch Centre, Cambridge, UK.

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http://dx.doi.org/10.1097/ACI.0000000000000316DOI Listing
December 2016

Differential Impairment of Interferon- Responses in Two Cases of Pulmonary Nontuberculous Mycobacterial Disease.

Case Reports Immunol 2016 16;2016:9165641. Epub 2016 Nov 16.

University Hospital Southampton NHS Foundation Trust, Southampton, UK; Academic Unit of Cancer Sciences, Faculty of Medicine, University of Southampton and Southampton NIHR Experimental Cancer Medicine Centre, Southampton, UK.

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http://dx.doi.org/10.1155/2016/9165641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128696PMC
November 2016

Anti-IFN-γ autoantibodies are strongly associated with HLA-DR*15:02/16:02 and HLA-DQ*05:01/05:02 across Southeast Asia.

J Allergy Clin Immunol 2016 Mar 29;137(3):945-8.e8. Epub 2015 Oct 29.

Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.1016/j.jaci.2015.09.018DOI Listing
March 2016

Protein microarrays identify disease-specific anti-cytokine autoantibody profiles in the landscape of immunodeficiency.

J Allergy Clin Immunol 2016 Jan 11;137(1):204-213.e3. Epub 2015 Sep 11.

Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, Calif; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.07.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715746PMC
January 2016

A novel insight into the immunologic basis of chronic granulomatous invasive fungal rhinosinusitis.

Allergy Rhinol (Providence) 2016 Jan;7(2):102-6

Department of Immunology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.2500/ar.2016.7.0162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010430PMC
January 2016

Pneumococcal polysaccharide vaccine responses are impaired in a subgroup of children with cystic fibrosis.

J Cyst Fibros 2014 Dec 11;13(6):632-8. Epub 2014 Mar 11.

Institute for Lung Health, NIHR Leicester Respiratory Biomedical Research Unit, Leicester LE1 9HN, UK; Department of Infection Immunity and Inflammation, University of Leicester, Leicester LE1 9HN, UK; Children's Hospital, Leicester Royal Infirmary, Leicester LE1 5WW, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jcf.2014.02.002DOI Listing
December 2014

Aberrant disgust responses and immune reactivity in cocaine-dependent men.

Biol Psychiatry 2014 Jan 3;75(2):140-7. Epub 2013 Oct 3.

Department of Clinical Biochemistry and Immunology, Cambridge University Hospitals National Health Service Foundation Trust, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2013.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898808PMC
January 2014

Recurrent mycobacterial infections in a patient with IL-12 deficiency.

BMJ Case Rep 2009 1;2009. Epub 2009 Dec 1.

Barts and the London NHS Trust, Immunology, 214, 80 Newark St, London E1 2ES, UK.

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http://dx.doi.org/10.1136/bcr.11.2008.1278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028165PMC
October 2012

Specific antibody deficiency in children with chronic wet cough.

Arch Dis Child 2012 May 30;97(5):478-80. Epub 2012 Jan 30.

Department of Paediatrics, University Hospitals of Leicester, Leicester, UK.

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http://dx.doi.org/10.1136/archdischild-2011-300691DOI Listing
May 2012

Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries.

Authors:
Ludovic de Beaucoudrey Arina Samarina Jacinta Bustamante Aurélie Cobat Stéphanie Boisson-Dupuis Jacqueline Feinberg Saleh Al-Muhsen Lucile Jannière Yoann Rose Maylis de Suremain Xiao-Fei Kong Orchidée Filipe-Santos Ariane Chapgier Capucine Picard Alain Fischer Figen Dogu Aydan Ikinciogullari Gonul Tanir Sami Al-Hajjar Suliman Al-Jumaah Husn H Frayha Zobaida AlSum Sulaiman Al-Ajaji Abdullah Alangari Abdulaziz Al-Ghonaium Parisa Adimi Davood Mansouri Imen Ben-Mustapha Judith Yancoski Ben-Zion Garty Carlos Rodriguez-Gallego Isabel Caragol Necil Kutukculer Dinakantha S Kumararatne Smita Patel Rainer Doffinger Andrew Exley Olle Jeppsson Janine Reichenbach David Nadal Yaryna Boyko Barbara Pietrucha Suzanne Anderson Michael Levin Liliane Schandené Kinda Schepers André Efira Françoise Mascart Masao Matsuoka Tatsunori Sakai Claire-Anne Siegrist Klara Frecerova Renate Blüetters-Sawatzki Jutta Bernhöft Joachim Freihorst Ulrich Baumann Darko Richter Filomeen Haerynck Frans De Baets Vas Novelli David Lammas Christiane Vermylen David Tuerlinckx Chris Nieuwhof Malgorzata Pac Walther H Haas Ingrid Müller-Fleckenstein Bernhard Fleckenstein Jacob Levy Revathi Raj Aileen Cleary Cohen David B Lewis Steven M Holland Kuender D Yang Xiaochuan Wang Xiaohong Wang Liping Jiang Xiqiang Yang Chaomin Zhu Yuanyuan Xie Pamela Pui Wah Lee Koon Wing Chan Tong-Xin Chen Gabriela Castro Ivelisse Natera Ana Codoceo Alejandra King Liliana Bezrodnik Daniela Di Giovani Maria Isabel Gaillard Dewton de Moraes-Vasconcelos Anete Sevciovic Grumach Alberto Jose da Silva Duarte Ruth Aldana Francisco Javier Espinosa-Rosales Mohammed Bejaoui Ahmed Aziz Bousfiha Jamila El Baghdadi Namik Ozbek Guzide Aksu Melike Keser Ayper Somer Nevin Hatipoglu Cigdem Aydogmus Suna Asilsoy Yildiz Camcioglu Saniye Gülle Tuba T Ozgur Meteran Ozen Matias Oleastro Andrea Bernasconi Setareh Mamishi Nima Parvaneh Sergio Rosenzweig Ridha Barbouche Sigifredo Pedraza Yu Lung Lau Mohammad S Ehlayel Claire Fieschi Laurent Abel Ozden Sanal Jean-Laurent Casanova

Medicine (Baltimore) 2010 Nov;89(6):381-402

Laboratory of Human Genetics of Infectious Diseases U980, Institut National de la Santé et de la Recherche Médicale, Paris, France.

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http://dx.doi.org/10.1097/MD.0b013e3181fdd832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129625PMC
November 2010

Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients.

J Allergy Clin Immunol 2010 Aug;126(2):332-7, 337.e1-2

Division of Immunology, Children's Hospital, Boston, and the Department of Pediatrics, Harvard Medical School, Boston, Mass, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749100081
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http://dx.doi.org/10.1016/j.jaci.2010.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917474PMC
August 2010

Host genetic factors and mycobacterial infections: lessons from single gene disorders affecting innate and adaptive immunity.

Microbes Infect 2006 Apr 19;8(4):1141-50. Epub 2006 Jan 19.

Department of Clinical Biochemistry and Immunology, Box 109, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.

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http://dx.doi.org/10.1016/j.micinf.2005.10.028DOI Listing
April 2006

Human immunodeficiencies that predispose to intracellular bacterial infections.

Curr Opin Rheumatol 2005 Jul;17(4):440-6

Department of Clinical Biochemistry and Immunology, Cambridge, United Kingdom.

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http://pdfs.journals.lww.com/co-rheumatology/2005/07000/Huma
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http://dx.doi.org/10.1097/01.bor.0000166387.70475.ddDOI Listing
July 2005

The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes.

Hum Mol Genet 2002 Oct;11(20):2371-5

Département de Génétique et Unité de Recherches sur les Handicaps Génétiques de l'Enfant INSERM UR-393, Hôpital Necker, 149 rue de Sèvres, 75743 Paris Cedex 15, France.

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http://dx.doi.org/10.1093/hmg/11.20.2371DOI Listing
October 2002