Publications by authors named "Rainer Claus"

79Publications

Autopsy of patients with COVID-19: A balance of fear and curiosity.

Pathol Res Pract 2020 08 31;216(8):153039. Epub 2020 May 31.

Hematology and Oncology, Medical Faculty, University of Augsburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2020.153039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261439PMC
August 2020

Postmortem Examination of Patients With COVID-19.

JAMA 2020 Jun;323(24):2518-2520

Department of Hematology and Clinical Oncology, University Medical Center Augsburg, Augsburg, Germany.

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http://dx.doi.org/10.1001/jama.2020.8907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243161PMC
June 2020

Genotyping of circulating cell-free DNA enables noninvasive tumor detection in myxoid liposarcomas.

Int J Cancer 2019 08 9;145(4):1148-1161. Epub 2019 Mar 9.

Department of Plastic and Hand Surgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/ijc.32216DOI Listing
August 2019

Decitabine in combination with donor lymphocyte infusions can induce remissions in relapsed myeloid malignancies with higher leukemic burden after allogeneic hematopoietic cell transplantation.

Leuk Res 2018 09 7;72:20-26. Epub 2018 Jul 7.

Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany; German Cancer Consortium (DKTK), Freiburg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.07.005DOI Listing
September 2018

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 Apr;24(4):526

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http://dx.doi.org/10.1038/nm0418-526cDOI Listing
April 2018

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Authors:
Nimitha R Mathew Francis Baumgartner Lukas Braun David O'Sullivan Simone Thomas Miguel Waterhouse Tony A Müller Kathrin Hanke Sanaz Taromi Petya Apostolova Anna L Illert Wolfgang Melchinger Sandra Duquesne Annette Schmitt-Graeff Lena Osswald Kai-Li Yan Arnim Weber Sonia Tugues Sabine Spath Dietmar Pfeifer Marie Follo Rainer Claus Michael Lübbert Christoph Rummelt Hartmut Bertz Ralph Wäsch Johanna Haag Andrea Schmidts Michael Schultheiss Dominik Bettinger Robert Thimme Evelyn Ullrich Yakup Tanriver Giang Lam Vuong Renate Arnold Philipp Hemmati Dominik Wolf Markus Ditschkowski Cordula Jilg Konrad Wilhelm Christian Leiber Sabine Gerull Jörg Halter Claudia Lengerke Thomas Pabst Thomas Schroeder Guido Kobbe Wolf Rösler Soroush Doostkam Stephan Meckel Kathleen Stabla Stephan K Metzelder Sebastian Halbach Tilman Brummer Zehan Hu Joern Dengjel Björn Hackanson Christoph Schmid Udo Holtick Christof Scheid Alexandros Spyridonidis Friedrich Stölzel Rainer Ordemann Lutz P Müller Flore Sicre-de-Fontbrune Gabriele Ihorst Jürgen Kuball Jan E Ehlert Daniel Feger Eva-Maria Wagner Jean-Yves Cahn Jacqueline Schnell Florian Kuchenbauer Donald Bunjes Ronjon Chakraverty Simon Richardson Saar Gill Nicolaus Kröger Francis Ayuk Luca Vago Fabio Ciceri Antonia M Müller Takeshi Kondo Takanori Teshima Susan Klaeger Bernhard Kuster Dennis Dong Hwan Kim Daniel Weisdorf Walter van der Velden Daniela Dörfel Wolfgang Bethge Inken Hilgendorf Andreas Hochhaus Geoffroy Andrieux Melanie Börries Hauke Busch John Magenau Pavan Reddy Myriam Labopin Joseph H Antin Andrea S Henden Geoffrey R Hill Glen A Kennedy Merav Bar Anita Sarma Donal McLornan Ghulam Mufti Betul Oran Katayoun Rezvani Omid Shah Robert S Negrin Arnon Nagler Marco Prinz Andreas Burchert Andreas Neubauer Dietrich Beelen Andreas Mackensen Nikolas von Bubnoff Wolfgang Herr Burkhard Becher Gerard Socié Michael A Caligiuri Eliana Ruggiero Chiara Bonini Georg Häcker Justus Duyster Jürgen Finke Erika Pearce Bruce R Blazar Robert Zeiser

Nat Med 2018 03 12;24(3):282-291. Epub 2018 Feb 12.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/nm.4484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029618PMC
March 2018

[Esophageal Adenocarcinoma - Appraisal of a Rapidly Increasing Disease].

Dtsch Med Wochenschr 2017 Sep 22;142(19):1453-1460. Epub 2017 Sep 22.

Klinik für Strahlentherapie - Universitätsklinikum Freiburg.

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http://dx.doi.org/10.1055/s-0043-115777DOI Listing
September 2017

The oligodendrocyte lineage transcription factor 2 (OLIG2) is epigenetically regulated in acute myeloid leukemia.

Exp Hematol 2017 11 28;55:76-85.e3. Epub 2017 Jul 28.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany; Department of Hematology/Oncology, Medical Center Augsburg, Augsburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X173070
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http://dx.doi.org/10.1016/j.exphem.2017.07.009DOI Listing
November 2017

Tumor-priming converts NK cells to memory-like NK cells.

Oncoimmunology 2017 18;6(6):e1317411. Epub 2017 Apr 18.

University Children´s Hospital, Dep. of Pediatric Hematology and Oncology, Eberhard Karls University, Tuebingen, Germany.

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http://dx.doi.org/10.1080/2162402X.2017.1317411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486172PMC
April 2017

Elevated fetal haemoglobin is a predictor of better outcome in MDS/AML patients receiving 5-aza-2'-deoxycytidine (Decitabine).

Br J Haematol 2017 02 1;176(4):609-617. Epub 2016 Dec 1.

Division of Haematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1111/bjh.14463DOI Listing
February 2017

PRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic stem and progenitor cells.

Sci Rep 2015 Jul 22;5:12319. Epub 2015 Jul 22.

Institute of Medical Radiology and Cell Research (MSZ) in the Center for Experimental Molecular Medicine (ZEMM), University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1038/srep12319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510577PMC
July 2015

Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemia.

Int J Cancer 2015 Sep 13;137(6):1352-61. Epub 2015 Mar 13.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29491DOI Listing
September 2015

DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood.

Int J Cancer 2015 Apr 24;136(8):1845-55. Epub 2014 Sep 24.

Molecular Biology of Breast Cancer, Department of Gynecology and Obstetrics, University of Heidelberg, Heidelberg, Germany; Molecular Epidemiology (C080), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29205DOI Listing
April 2015

Tumor cell heterogeneity in Small Cell Lung Cancer (SCLC): phenotypical and functional differences associated with Epithelial-Mesenchymal Transition (EMT) and DNA methylation changes.

PLoS One 2014 24;9(6):e100249. Epub 2014 Jun 24.

Department of Hematology/Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany; University Furtwangen, Faculty of Medical and Life Sciences, Campus VS-Schwenningen, Villingen-Schwenningen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100249PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069054PMC
March 2015

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia.

Cancer Discov 2014 Mar 19;4(3):348-61. Epub 2013 Dec 19.

Divisions of 1Epigenomics and Cancer Risk Factors, 2Theoretical Bioinformatics, 3Biostatistics, and 4Molecular Genetics; 5Department of Translational Oncology, National Center for Tumor Diseases (NCT), The German Cancer Research Center (DKFZ); 6Department of Medicine V, University of Heidelberg, Heidelberg; 7Department of Medicine, University of Freiburg Medical Center, Freiburg; 8Department of Internal Medicine III, University of Ulm, Ulm; 9The German Cancer Consortium, Germany; 10Department of Medicine, University of California at San Diego Moores Cancer Center, La Jolla, California; and 11Division of Hematology, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134522PMC
March 2014

Promoter DNA methylation regulates progranulin expression and is altered in FTLD.

Acta Neuropathol Commun 2013 May 13;1:16. Epub 2013 May 13.

German Center for Neurodegenerative Diseases (DZNE), University of Munich, Schillerstr, 44, Munich 80336, Germany.

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http://dx.doi.org/10.1186/2051-5960-1-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893557PMC
May 2013

Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer.

Nat Rev Genet 2013 Nov 9;14(11):765-80. Epub 2013 Oct 9.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ).

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http://dx.doi.org/10.1038/nrg3554DOI Listing
November 2013

Genome-wide epigenetic regulation of miRNAs in cancer.

Cancer Res 2013 Jan 10;73(2):473-7. Epub 2013 Jan 10.

Department of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://cancerres.aacrjournals.org/content/early/2013/01/10/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-3731DOI Listing
January 2013

Decitabine induces very early in vivo DNA methylation changes in blasts from patients with acute myeloid leukemia.

Leuk Res 2013 Feb 15;37(2):190-6. Epub 2012 Nov 15.

Division Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.leukres.2012.10.015DOI Listing
February 2013

A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR.

Epigenetics 2012 Jul 1;7(7):772-80. Epub 2012 Jul 1.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://www.tandfonline.com/doi/abs/10.4161/epi.20299
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http://dx.doi.org/10.4161/epi.20299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414395PMC
July 2012

Genome-wide epigenetic modifications in cancer.

Prog Drug Res 2011 ;67:25-49

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066002PMC
http://dx.doi.org/10.1007/978-3-7643-8989-5_2DOI Listing
January 2011

Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL.

Blood 2011 Jan 22;117(3):862-71. Epub 2010 Nov 22.

Department of Molecular Virology, Immunology, and Medical Genetics, Human Cancer Genetics Program, the Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1182/blood-2010-05-284638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035078PMC
January 2011

DNA methylation profiling in acute myeloid leukemia: from recent technological advances to biological and clinical insights.

Future Oncol 2010 Sep;6(9):1415-31

Department of Epigenomics & Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.2217/fon.10.110DOI Listing
September 2010

Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia.

Cancer Res 2008 May;68(9):3142-51

Department of Molecular Virology, Immunology and Medical Genetics, Division of Human Cancer Genetics, College of Pharmacy, Ohio State University, Columbus, Ohio, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-08-0483DOI Listing
May 2008

Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression.

J Leukoc Biol 2006 Dec 25;80(6):1462-72. Epub 2006 Sep 25.

Division Hematology/Oncology, University of Freiburg Medical Center, Hugstetter Str. 55, Freiburg D-79106, Germany.

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http://doi.wiley.com/10.1189/jlb.0106005
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http://dx.doi.org/10.1189/jlb.0106005DOI Listing
December 2006

Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents.

Semin Oncol 2005 Oct;32(5):511-20

Department Internal Medicine I, Division Hematology/Oncology, University of Freiburg Medical Center, Hugstetterstrasse 55, D-79106 Freiburg, Germany.

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http://dx.doi.org/10.1053/j.seminoncol.2005.07.024DOI Listing
October 2005

Epigenetic targets in hematopoietic malignancies.

Oncogene 2003 Sep;22(42):6489-96

Department Internal Medicine I, Division Hematology/Oncology, University of Freiburg Medical Center, Hugstetter Str., D-79106 Freiburg, Germany.

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http://web.stanford.edu/class/archive/cbio/cbio241/cbio241.1
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http://www.nature.com/doifinder/10.1038/sj.onc.1206814
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http://dx.doi.org/10.1038/sj.onc.1206814DOI Listing
September 2003