Rafik Tadros

Rafik Tadros

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Rafik Tadros

Rafik Tadros

Publications by authors named "Rafik Tadros"

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Predicting cardiac electrical response to sodium-channel blockade and Brugada syndrome using polygenic risk scores.

Eur Heart J 2019 Oct;40(37):3097-3107

Department of Clinical and Experimental Cardiology, Amsterdam UMC, University of Amsterdam, Heart Center, Amsterdam Cardiovascular Sciences, Meibergdreef 9, AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehz435DOI Listing
October 2019

Risk stratification for ventricular arrhythmias and sudden cardiac death in arrhythmogenic right ventricular cardiomyopathy: an update.

Expert Rev Cardiovasc Ther 2019 Sep 21;17(9):645-651. Epub 2019 Aug 21.

Department of Medicine, Montreal Heart Institute , Montreal , Quebec , Canada.

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http://dx.doi.org/10.1080/14779072.2019.1657831DOI Listing
September 2019

Pharmacotherapy in inherited and acquired ventricular arrhythmia in structurally normal adult hearts.

Expert Opin Pharmacother 2019 Sep 30:1-14. Epub 2019 Sep 30.

Electrophysiology service, Montreal Heart Institute , Montreal , Quebec , Canada.

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http://dx.doi.org/10.1080/14656566.2019.1669561DOI Listing
September 2019

An integrated overview of AV node physiology.

Pacing Clin Electrophysiol 2019 Jul 10;42(7):805-820. Epub 2019 Jun 10.

Département de Physiologie, Faculté de Médecine, Université de Montréal, Montréal, Canada.

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http://dx.doi.org/10.1111/pace.13734DOI Listing
July 2019

Pregnancy in Catecholaminergic Polymorphic Ventricular Tachycardia.

JACC Clin Electrophysiol 2019 Mar 26;5(3):387-394. Epub 2018 Dec 26.

Heart Rhythm Services, Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jacep.2018.10.019DOI Listing
March 2019

Mechanisms and Clinical Significance of Arrhythmia-Induced Cardiomyopathy.

Can J Cardiol 2018 11 1;34(11):1449-1460. Epub 2018 Aug 1.

Research Center, Montréal Heart Institute, Montréal, Québec, Canada; Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada; Cardiovascular Genetics Center, Montréal Heart Institute, Montréal, Québec, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0828282X183099
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http://dx.doi.org/10.1016/j.cjca.2018.07.475DOI Listing
November 2018

Bioinformatic analysis of a plakophilin-2-dependent transcription network: implications for the mechanisms of arrhythmogenic right ventricular cardiomyopathy in humans and in boxer dogs.

Europace 2018 Nov;20(suppl_3):iii125-iii132

The Leon H Charney Division of Cardiology, New York University School of Medicine, 435 East 30th Street. SB 707, New York, NY, USA.

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http://dx.doi.org/10.1093/europace/euy238DOI Listing
November 2018

SCN5A mutation type and topology are associated with the risk of ventricular arrhythmia by sodium channel blockers.

Int J Cardiol 2018 Sep 30;266:128-132. Epub 2018 Apr 30.

Heart Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ijcard.2017.09.010DOI Listing
September 2018

Atrial fibrillation in young patients.

Expert Rev Cardiovasc Ther 2018 Jul 2;16(7):489-500. Epub 2018 Jul 2.

a Electrophysiology Service , Montreal Heart Institute, Université de Montréal , Montreal , Canada.

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http://dx.doi.org/10.1080/14779072.2018.1490644DOI Listing
July 2018

Quinidine effective for the management of ventricular and atrial arrhythmias associated with Brugada syndrome.

HeartRhythm Case Rep 2018 Jul 30;4(7):270-272. Epub 2018 Apr 30.

Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.hrcr.2018.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050440PMC
July 2018

Yield and Pitfalls of Ajmaline Testing in the Evaluation of Unexplained Cardiac Arrest and Sudden Unexplained Death: Single-Center Experience With 482 Families.

JACC Clin Electrophysiol 2017 12 28;3(12):1400-1408. Epub 2017 Jun 28.

Heart Center, Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jacep.2017.04.005DOI Listing
December 2017

Risk of arrhythmic events in drug-induced Brugada syndrome.

Heart Rhythm 2017 10 27;14(10):1434-1435. Epub 2017 Jun 27.

Heart Centre, Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Cardiovascular Genetics Center, Montreal Heart Institute, Montreal, Quebec, Canada; Department of Medicine, Université de Montréal, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.06.033DOI Listing
October 2017

Revisiting the sensitivity of sodium channel blocker testing in Brugada syndrome using obligate transmittance.

Int J Cardiol 2017 10 5;245:183-184. Epub 2017 Jul 5.

Heart Centre, Department of Cardiology, Academic Medical Center, The Netherlands; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, Jeddah, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.07.006DOI Listing
October 2017

The Brugada Syndrome Susceptibility Gene Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity.

Circ Res 2017 Aug 21;121(5):537-548. Epub 2017 Jun 21.

From the Department of Clinical and Experimental Cardiology, Heart Center, Academic Medical Center, Amsterdam, The Netherlands (C.C.V., S.P., R.T., E.M.L., I.M., L.B., A.A.M.W., R.C., A.O.V., C.A.R., C.R.B.); Department of Medicine, Cardiovascular Genetics Center, Montreal Heart Institute, Canada (R.T.); Université de Montréal, Canada (R.T.); Department of Medical Biology, Academic Medical Center, Amsterdam, The Netherlands (B.d.J., R.W., B.J.B., A.O.V.); INSERM, CNRS, Université de Nantes, L'institut du Thorax, Nantes, France (J.B.); Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, Jeddah, Saudi Arabia (A.A.M.W.); and Electrophysiology and Heart Modeling Institute LIRYC, Université de Bordeaux, France (R.C.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.117.31095
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http://dx.doi.org/10.1161/CIRCRESAHA.117.310959DOI Listing
August 2017

Dissecting the Genetic Basis of the ECG as a Means of Understanding Mechanisms of Arrhythmia.

Circ Cardiovasc Genet 2017 08;10(4)

From the Department of Clinical and Experimental Cardiology, Heart Center, Academic Medical Center, Amsterdam, The Netherlands (R.T., R.C., C.R.B.); and Department of Medicine, Cardiovascular Genetics Center, Montreal Heart Institute and Université de Montréal, Quebec, Canada (R.T.).

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001858DOI Listing
August 2017

Exome sequencing identifies primary carnitine deficiency in a family with cardiomyopathy and sudden death.

Eur J Hum Genet 2017 06 15;25(6):783-787. Epub 2017 Mar 15.

Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2017.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477358PMC
June 2017

Familial Disease Is Not Always Genetic: A Family With Atrioventricular Block and Mitral Regurgitation.

Can J Cardiol 2017 04 16;33(4):554.e9-554.e11. Epub 2016 Dec 16.

Heart Center, Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, the Netherlands; Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2016.11.025DOI Listing
April 2017

Decreased Mortality With Beta-Blockers in Patients With Heart Failure and Coexisting Atrial Fibrillation: An AF-CHF Substudy.

JACC Heart Fail 2017 02 11;5(2):99-106. Epub 2017 Jan 11.

Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada; Montreal Health Innovations Coordinating Center, Université de Montréal, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jchf.2016.10.015DOI Listing
February 2017

Predictors of Ventricular Arrhythmias and Sudden Death in a Québec Cohort With Brugada Syndrome.

Can J Cardiol 2016 11 31;32(11):1355.e1-1355.e7. Epub 2016 Mar 31.

Department of Medicine, Montreal Heart Institute, Université de Montréal, Montréal, Québec, Canada; Montréal Health Innovations Coordinating Center (MHICC), Montréal Heart Institute, Montréal, Québec, Canada.

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http://dx.doi.org/10.1016/j.cjca.2016.03.012DOI Listing
November 2016

Does Electrode Design Matter in Ablation Effect Assessments?

J Cardiovasc Electrophysiol 2016 07 3;27(7):825-6. Epub 2016 Jun 3.

Département de médecine, Faculté de médecine, Université de Montréal, Montreal, Canada.

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http://dx.doi.org/10.1111/jce.13011DOI Listing
July 2016

Dronedarone: Basic Pharmacology and Clinical Use.

Card Electrophysiol Clin 2016 06 19;8(2):453-65. Epub 2016 Mar 19.

Department of Medicine, Université de Montréal and Montreal Heart Institute, 5000 Rue Belanger, Montreal, Québec H1T 1C8, Canada; Heart Rhythm Services, Department of Medicine, University of British Columbia, 2775 Laurel Street, Vancouver, British Columbia V5Z 1M9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccep.2016.02.008DOI Listing
June 2016

Pharmacotherapy for inherited arrhythmia syndromes: mechanistic basis, clinical trial evidence and practical application.

Expert Rev Cardiovasc Ther 2015 20;13(7):769-82. Epub 2015 May 20.

Electrophysiology service and Cardiovascular Genetics Center, Montreal Heart Institute, Université de Montréal, 5000 Bélanger St. E., Montreal, Quebec, H1T 1C8 Canada.

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http://dx.doi.org/10.1586/14779072.2015.1049156DOI Listing
February 2016

Risk stratification for sudden death in arrhythmogenic right ventricular cardiomyopathy.

Expert Rev Cardiovasc Ther 2015 Jun 6;13(6):653-64. Epub 2015 May 6.

From the Electrophysiology Service, Montreal Heart Institute and Department of Medicine, Université de Montréal, 5000 Bélanger St. E., Montreal, Quebec, H1T 1C8, Canada.

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http://www.tandfonline.com/doi/full/10.1586/14779072.2015.10
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http://dx.doi.org/10.1586/14779072.2015.1043891DOI Listing
June 2015

Continuous sensing of sympathetic tone: an eventual clinical tool.

J Cardiovasc Electrophysiol 2015 Jan 12;26(1):79-81. Epub 2014 Oct 12.

Département de physiologie, Faculté de médecine, Université de Montréal, Montréal, Canada.

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http://dx.doi.org/10.1111/jce.12548DOI Listing
January 2015

Nonsense mutations in BAG3 are associated with early-onset dilated cardiomyopathy in French Canadians.

Can J Cardiol 2014 Dec 2;30(12):1655-61. Epub 2014 Oct 2.

Centre de Recherche, Montreal Heart Institute, Montréal, Québec, Canada; Départment de Médecine, Faculté de médecine, Université de Montréal, Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2014.09.030DOI Listing
December 2014

Sex differences in cardiac electrophysiology and clinical arrhythmias: epidemiology, therapeutics, and mechanisms.

Can J Cardiol 2014 Jul 28;30(7):783-92. Epub 2014 Mar 28.

Research Center, Montreal Heart Institute and Université de Montréal, Montreal, Québec, Canada; Department of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2014.03.032DOI Listing
July 2014

Atrial fibrillation in heart failure: drug therapies for rate and rhythm control.

Heart Fail Rev 2014 May;19(3):315-24

Department of Medicine, Montreal Heart Institute, Université de Montréal, 5000 Belanger St. E, Montreal, QC, H1T 1C8, Canada.

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http://dx.doi.org/10.1007/s10741-013-9395-6DOI Listing
May 2014

Integrated rate-dependent and dual pathway AV nodal functions: principles and assessment framework.

Am J Physiol Heart Circ Physiol 2014 Jan 8;306(2):H173-83. Epub 2013 Nov 8.

Département de physiologie, Faculté de médecine, Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1152/ajpheart.00516.2013DOI Listing
January 2014

Concealed autonomic mechanisms underlying atrial fibrillation.

J Cardiovasc Electrophysiol 2013 Feb 7;24(2):196-8. Epub 2012 Dec 7.

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http://dx.doi.org/10.1111/jce.12050DOI Listing
February 2013

Rate-dependent AV nodal function: closely bound conduction and refractory properties.

J Cardiovasc Electrophysiol 2012 Mar 28;23(3):302-8. Epub 2011 Sep 28.

Département de Physiologie, Faculté de Médecine, Université de Montréal, Montréal, Canada.

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http://doi.wiley.com/10.1111/j.1540-8167.2011.02180.x
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http://dx.doi.org/10.1111/j.1540-8167.2011.02180.xDOI Listing
March 2012

What does dual pathway Wenckebach mean?

J Cardiovasc Electrophysiol 2011 Nov 2;22(11):1263-5. Epub 2011 Jun 2.

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http://doi.wiley.com/10.1111/j.1540-8167.2011.02088.x
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http://dx.doi.org/10.1111/j.1540-8167.2011.02088.xDOI Listing
November 2011

Imminent ganglionic ventricular rate control during atrial fibrillation.

J Cardiovasc Electrophysiol 2010 Feb 10;21(2):200-2. Epub 2009 Nov 10.

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http://dx.doi.org/10.1111/j.1540-8167.2009.01642.xDOI Listing
February 2010

Rate-dependent AV nodal refractoriness: a new functional framework based on concurrent effects of basic and pretest cycle length.

Am J Physiol Heart Circ Physiol 2009 Dec 9;297(6):H2136-43. Epub 2009 Oct 9.

Département de physiologie, Faculté de médecine, Université de Montreal, CP 6128 Succ CV, Montréal, Quebec, Canada H3C 3J7.

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http://dx.doi.org/10.1152/ajpheart.00712.2009DOI Listing
December 2009

Dependence of AV nodal function curves on the selected recovery index: pivotal role of pretest conduction time.

J Cardiovasc Electrophysiol 2007 Sep 26;18(9):978-84. Epub 2007 Jul 26.

Département de physiologie, Faculté de médecine, Université de Montréal, Montréal, Canada.

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http://dx.doi.org/10.1111/j.1540-8167.2007.00895.xDOI Listing
September 2007

Unified rate-dependent atrioventricular nodal function: consistent recovery and fatigue properties revealed with S1S2S3 protocols and different recovery indexes.

Heart Rhythm 2006 Aug 22;3(8):959-66. Epub 2006 Apr 22.

Département de Physiologie, Faculté de Médecine, Université de Montréal, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.hrthm.2006.04.017DOI Listing
August 2006

Role of compact node and posterior extension in direction-dependent changes in atrioventricular nodal function in rabbit.

J Cardiovasc Electrophysiol 2003 Dec;14(12):1342-50

Département de Physiologie, Faculté de Médecine, Université de Montréal, Canada.

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http://dx.doi.org/10.1046/j.1540-8167.2003.03382.xDOI Listing
December 2003