Raffaella Sordella

Raffaella Sordella

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Raffaella Sordella

Raffaella Sordella

Publications by authors named "Raffaella Sordella"

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32Publications

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The Evolution of Mutations: From Loss-of-Function to Separation-of-Function Mutants.

J Cancer Biol Res 2016 23;4(4). Epub 2016 Dec 23.

Cancer Center, Cold Spring Harbor Laboratory, USA; Graduate Program in Genetics, Stony Brook University, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298884PMC
December 2016

Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas.

Sci Rep 2016 06 15;6:27891. Epub 2016 Jun 15.

Department of Pathology, Stony Brook University, Stony Brook, NY, 11794, USA.

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http://dx.doi.org/10.1038/srep27891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908391PMC
June 2016

TAp73 is essential for germ cell adhesion and maturation in testis.

J Cell Biol 2014 Mar 24;204(7):1173-90. Epub 2014 Mar 24.

Department of Molecular Oncology, University of Göttingen, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1083/jcb.201306066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971741PMC
March 2014

Dialogue between RhoA/ROCK and members of the Par complex in cell polarity.

Dev Cell 2008 Feb;14(2):150-2

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153458070800043
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http://dx.doi.org/10.1016/j.devcel.2008.01.015DOI Listing
February 2008

Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib.

Cancer Res 2007 Mar;67(5):2325-30

Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4293DOI Listing
March 2007

Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development.

Dev Neurosci 2006 ;28(6):538-50

Department of Biology, Calvin College, Grand Rapids, MI, USA.

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http://dx.doi.org/10.1159/000095116DOI Listing
November 2006

Driving actin dynamics under the influence of alcohol.

Cell 2006 Oct;127(1):37-9

Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center and Harvard Medical School, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.cell.2006.09.017DOI Listing
October 2006

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752.

Proc Natl Acad Sci U S A 2006 Feb 6;103(7):2316-21. Epub 2006 Feb 6.

Cancer Center and Department of Pathology, Molecular Pathology Research Unit, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1073/pnas.0508776103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413705PMC
February 2006

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

Nat Genet 2005 Dec 30;37(12):1315-6. Epub 2005 Oct 30.

Massachusetts General Hospital Cancer Center, Harvard Medical School, 13th Street, Charlestown, Massachusetts 02129, USA.

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http://www.nature.com/articles/ng1671
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http://dx.doi.org/10.1038/ng1671DOI Listing
December 2005

p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling.

J Cell Sci 2005 Oct 27;118(Pt 20):4689-700. Epub 2005 Sep 27.

Institute for Cancer Research and Treatment (IRCC), University of Turin Medical School, Candiolo, Torino 10060, Italy.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.02590
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http://dx.doi.org/10.1242/jcs.02590DOI Listing
October 2005

An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression.

Mol Cell 2005 Jan;17(1):23-35

Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, MA 02129, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650400715
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http://dx.doi.org/10.1016/j.molcel.2004.11.024DOI Listing
January 2005

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways.

Science 2004 Aug 29;305(5687):1163-7. Epub 2004 Jul 29.

Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center and Harvard Medical School, Building 149, 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1126/science.1101637DOI Listing
August 2004

Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis.

Cell 2003 Apr;113(2):147-58

Massachusetts General Hospital Cancer Center and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00271-xDOI Listing
April 2003

DOCK4, a GTPase activator, is disrupted during tumorigenesis.

Cell 2003 Mar;112(5):673-84

Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/s0092-8674(03)00155-7DOI Listing
March 2003