Raffaella Grimaldi

Raffaella Grimaldi

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Raffaella Grimaldi

Raffaella Grimaldi

Publications by authors named "Raffaella Grimaldi"

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11Publications

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Screening a protein kinase inhibitor library against Plasmodium falciparum.

Malar J 2017 11 7;16(1):446. Epub 2017 Nov 7.

Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.

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http://dx.doi.org/10.1186/s12936-017-2085-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678585PMC
November 2017

The design and synthesis of potent and selective inhibitors of Trypanosoma brucei glycogen synthase kinase 3 for the treatment of human african trypanosomiasis.

J Med Chem 2014 Sep 8;57(18):7536-49. Epub 2014 Sep 8.

Drug Discovery Unit, College of Life Sciences, University of Dundee , Sir James Black Centre, Dow Street, Dundee DD1 5EH, U.K.

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http://dx.doi.org/10.1021/jm500239bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175002PMC
September 2014

From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules.

ChemMedChem 2013 Jul 14;8(7):1127-37. Epub 2013 Jun 14.

Drug Discovery Unit (DDU), Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Sir James Black Centre, DD1 5EH, UK.

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http://dx.doi.org/10.1002/cmdc.201300072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728731PMC
July 2013

Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.

ACS Chem Biol 2012 Nov 23;7(11):1858-65. Epub 2012 Aug 23.

Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, U.K.

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http://dx.doi.org/10.1021/cb300326zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621575PMC
November 2012

IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening.

PLoS One 2012 25;7(4):e35792. Epub 2012 Apr 25.

Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035792PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340893PMC
September 2012

Nuclear DBF-2-related kinases are essential regulators of cytokinesis in bloodstream stage Trypanosoma brucei.

J Biol Chem 2010 May 15;285(20):15356-68. Epub 2010 Mar 15.

Division of Infection & Immunity, Faculty of Biomedical and Life Sciences and Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Glasgow G12 8QQ, Scotland, UK.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.074591
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http://dx.doi.org/10.1074/jbc.M109.074591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865264PMC
May 2010