Raffaele Izzo

Raffaele Izzo

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Raffaele Izzo

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Are We Underestimating Prehypertension?

Hypertension 2019 Mar;73(3):541-542

From the Hypertension Research Center and Department of Advanced Biomedical Science, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12310DOI Listing
March 2019

Correction: Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

September 2018

Left atrial dilatation: A target organ damage in young to middle-age hypertensive patients. The Campania Salute Network.

Int J Cardiol 2018 Aug 27;265:229-233. Epub 2018 Mar 27.

Department of Advanced Medical Sciences, Federico II University of Naples, Italy; Hypertension Research Center, Federico II University of Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.03.120DOI Listing
August 2018

Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration.

PLoS One 2018 12;13(4):e0191172. Epub 2018 Apr 12.

Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191172PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896895PMC
July 2018

Left ventricular hypertrophy offsets the sex difference in cardiovascular risk (the Campania Salute Network).

Int J Cardiol 2018 05;258:257-261

Hypertension Research Center, Federico II University Hospital, Naples, Italy; Department of Translational Medical Sciences, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2017.12.086DOI Listing
May 2018

Determinants of decline of renal function in treated hypertensive patients: the Campania Salute Network.

Nephrol Dial Transplant 2018 Mar;33(3):435-440

Hypertension Research Center, University of Naples, Federico II, Naples, Italy.

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http://dx.doi.org/10.1093/ndt/gfx062DOI Listing
March 2018

Higher pulse pressure and risk for cardiovascular events in patients with essential hypertension: The Campania Salute Network.

Eur J Prev Cardiol 2018 02 11;25(3):235-243. Epub 2017 Dec 11.

1 Hypertension Research Center, Federico II University Hospital, Italy.

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http://dx.doi.org/10.1177/2047487317747498DOI Listing
February 2018

Diuretic therapy in hypertension: is it still the first choice?

J Cardiovasc Med (Hagerstown) 2018 Feb;19 Suppl 1:e123-e125

Hypertension Research Center.

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http://dx.doi.org/10.2459/JCM.0000000000000598DOI Listing
February 2018

Hypertension Survey in Italy: Novel Findings from the Campania Salute Network.

High Blood Press Cardiovasc Prev 2017 Dec 1;24(4):363-370. Epub 2017 Jul 1.

Hypertension Research Center, Federico II University, Naples, Italy.

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http://dx.doi.org/10.1007/s40292-017-0220-5DOI Listing
December 2017

Differential effect of obesity on prevalence of cardiac and carotid target organ damage in hypertension (the Campania Salute Network).

Int J Cardiol 2017 Oct 10;244:260-264. Epub 2017 Jun 10.

Hypertension Research Center, Federico II University Hospital, Naples, Italy; Department of Translational Medical Science, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2017.06.045DOI Listing
October 2017

Outcomes after non-cardiac surgery: mortality, complications, disability, and rehospitalization.

Monaldi Arch Chest Dis 2017 07 18;87(2):840. Epub 2017 Jul 18.

University of Naples Federico II, Department of Clinical Medicine and Surgery.

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http://dx.doi.org/10.4081/monaldi.2017.840DOI Listing
July 2017

Evolution of surgical techniques for a progressive risk reduction.

Monaldi Arch Chest Dis 2017 07 18;87(2):844. Epub 2017 Jul 18.

University of Naples Federico II, Department of Clinical Medicine and Surgery.

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http://dx.doi.org/10.4081/monaldi.2017.844DOI Listing
July 2017

Validation of Left Atrial Volume Estimation by Left Atrial Diameter from the Parasternal Long-Axis View.

J Am Soc Echocardiogr 2017 Mar 31;30(3):262-269. Epub 2016 Dec 31.

Hypertension Research Center, Federico II University Hospital, Naples, Italy; Department of Advanced Biomedical Sciences, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1016/j.echo.2016.11.017DOI Listing
March 2017

Platelet reactivity in patients carrying the e-NOS G894T polymorphism after a loading dose of aspirin plus clopidogrel.

Thromb Res 2017 03 27;151:72-73. Epub 2017 Jan 27.

Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy; Cardiovascular Center Aalst OLV Hospital, Aalst, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2017.01.011DOI Listing
March 2017

Development of Left Ventricular Hypertrophy in Treated Hypertensive Outpatients: The Campania Salute Network.

Hypertension 2017 01 28;69(1):136-142. Epub 2016 Nov 28.

From the Hypertension Research Center (R.I., M.-A.L., E.S., M.T.L., G.C., G.E., E.B., N.D.L., B.T., G.d.S.), Department of Translational Medical Sciences (R.I., G.C., N.D.L., G.d.S.), and Department of Advanced Biomedical Sciences (M.-A.L., E.S., G.E., E.B., B.T.), Federico II University, Naples, Italy; and Department of Clinical Science, University of Bergen, Norway (M.T.L.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08158DOI Listing
January 2017

Effects of a Novel Fixed Combination of Nutraceuticals on Serum Uric Acid Concentrations and the Lipid Profile in Asymptomatic Hyperuricemic Patients : Results from the PICONZ-UA Study.

High Blood Press Cardiovasc Prev 2016 Dec 19;23(4):381-386. Epub 2016 Sep 19.

Department of Medicine, Life and Environmental Sciences, L'Aquila University, Coppito, Italy.

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http://dx.doi.org/10.1007/s40292-016-0168-xDOI Listing
December 2016

Obesity and hypertensive heart disease: focus on body composition and sex differences.

Diabetol Metab Syndr 2016 30;8:79. Epub 2016 Nov 30.

Hypertension Research Center, Federico II University Hospital, Via S. Pansini 5, Building 1, 80131 Naples, Italy.

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http://dx.doi.org/10.1186/s13098-016-0193-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129668PMC
November 2016

Atrial Dilatation Development in Hypertensive Treated Patients: The Campania-Salute Network.

Am J Hypertens 2016 09 11;29(9):1077-84. Epub 2016 May 11.

Hypertension Research Center, University Federico II of Naples, Napoli, Italy; Department of Advanced Biomedical Sciences, University Federico II of Naples, Napoli, Italy;

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http://dx.doi.org/10.1093/ajh/hpw043DOI Listing
September 2016

Depressed myocardial energetic efficiency is associated with increased cardiovascular risk in hypertensive left ventricular hypertrophy.

J Hypertens 2016 09;34(9):1846-53

aHypertension Research Center bDepartment of Advanced Translational Medical Sciences cDepartment of Biomedical Sciences dDepartment of Neurosciences, Federico II University Hospital, Napoli, Italy.

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http://dx.doi.org/10.1097/HJH.0000000000001007DOI Listing
September 2016

Impact of pulse pressure on left ventricular global longitudinal strain in normotensive and newly diagnosed, untreated hypertensive patients.

J Hypertens 2016 06;34(6):1201-7

aHypertension Research Center (CIRIAPA) bDepartment of Advanced Biomedical Sciences cDepartment of Translational Medical Sciences, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0000000000000906DOI Listing
June 2016

Aortic root dimension and arterial stiffness in arterial hypertension: the Campania Salute Network.

J Hypertens 2016 06;34(6):1109-14

aHypertension Research Center bDepartment of Translational Medical Science, Federico II University Hospital, Naples, Italy cDepartment of Clinical Science, University of Bergen, Bergen, Norway dDepartment of Advanced Biomedical Sciences, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0000000000000932DOI Listing
June 2016

Real Data on Effectiveness, Tolerability and Safety of New Oral Anticoagulant Agents: Focus on Dabigatran.

High Blood Press Cardiovasc Prev 2016 Jun 20;23(2):115-22. Epub 2016 May 20.

Division of Cardiology, Department of Advanced Biomedical Sciences, Hypertension Research Centre, University of Napoli "Federico II", Naples, Italy.

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http://dx.doi.org/10.1007/s40292-016-0150-7DOI Listing
June 2016

Development of new atherosclerotic plaque in hypertensive patients: an observational registry study from the Campania-Salute network.

J Hypertens 2015 Dec;33(12):2471-6

aHypertension Research Center bDepartment of Translational Medical Sciences cDepartment of Advanced Biomedical Sciences dDepartment of Neurosciences, Federico II University, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0000000000000740DOI Listing
December 2015

Cardiovascular ultrasound exploration contributes to predict incident atrial fibrillation in arterial hypertension: the Campania Salute Network.

Int J Cardiol 2015 Nov 12;199:290-5. Epub 2015 Jul 12.

Hypertension Research Center, Federico II University, Naples, Italy; Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2015.07.019DOI Listing
November 2015

Hemodynamic Correlates of Abnormal Aortic Root Dimension in an Adult Population: The Strong Heart Study.

J Am Heart Assoc 2015 Sep 28;4(10):e002309. Epub 2015 Sep 28.

Department of Medicine, Weill-Cornell Medical College, New York, NY (G.S., M.J.R., R.B.D.).

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http://dx.doi.org/10.1161/JAHA.115.002309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845134PMC
September 2015

Pentraxin 3 Induces Vascular Endothelial Dysfunction Through a P-selectin/Matrix Metalloproteinase-1 Pathway.

Circulation 2015 Apr 6;131(17):1495-505; discussion 1505. Epub 2015 Mar 6.

From IRCCS Neuromed, Pozzilli, Italy (A.C., A.D., F.B., M.A., M.M., F.F., C.V.); University of Pisa, Department of Human Morphology and Applied Biology, Italy (P.L., F.F.); Laboratory of Immunology, Institute of Experimental Endocrinology and Oncology, National Research Council of Italy (IEOS-CNR), c/o Department of Molecular Medicine and Medical Biotechnology, University of Naples "Federico II", Napoli, Italy; (C.P., V.G.); University of Salerno, Department of Pharmaceutical Sciences, Fisciano (Salerno), Italy (G.A.); University of Salerno, Medicine and Surgery, Baronissi (Salerno), Italy (G.A., P.R., A.A.P., G.M., C.V.); Hypertension Research Center and Department of Advanced Biomedical Sciences (D.G.C., B.T.) and Department of Translational Medical Sciences (R.I.), University of Naples "Federico II", Napoli, Italy; University of Pavia, Department of Industrial and Information Engineering, Italy (A. Malovini); Department of Science and Technology, University of Sannio, Benevento, Italy (L.F.); Pathology Unit, "Istituto Nazionale Tumori, IRCCS, Fondazione Pascale," Naples, Italy (V.G.); and IRCCS Multimedica, Milan, Italy (A.A.P., G.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.014822DOI Listing
April 2015

Cardiovascular risk in relation to a new classification of hypertensive left ventricular geometric abnormalities.

J Hypertens 2015 Apr;33(4):745-54; discussion 754

aHypertension Research Center bDepartment of Translational Medical Sciences, Federico II University, Naples, Italy cDivision of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA dDepartment of Medicine and Surgery, University of Salerno, Salerno eDepartment of Neurosciences; Federico II University, Naples fDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0000000000000477DOI Listing
April 2015

Should thiazide diuretics be given as first line antihypertensive therapy or in addition to other medications?

High Blood Press Cardiovasc Prev 2015 Mar 24;22(1):55-9. Epub 2014 Jun 24.

Hypertension Research Center, Federico II University Hospital, via S. Pansini 5, bld. 2, 80131, Naples, Italy.

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http://link.springer.com/10.1007/s40292-014-0065-0
Publisher Site
http://dx.doi.org/10.1007/s40292-014-0065-0DOI Listing
March 2015

Hypertensive target organ damage predicts incident diabetes mellitus.

Eur Heart J 2013 Nov 23;34(44):3419-26. Epub 2013 Jul 23.

Department of Translational Medical Sciences, Federico II University Hospital, via S. Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1093/eurheartj/eht281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836008PMC
November 2013

Are observational studies more informative than randomized controlled trials in hypertension? Pro side of the argument.

Hypertension 2013 Sep;62(3):463-9

Department of Translational Medical Sciences, Hypertension Center, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.00727DOI Listing
September 2013

Heart rate variability and renal organ damage in hypertensive patients.

Conf Proc IEEE Eng Med Biol Soc 2012 ;2012:3825-8

Department of Electronics, Computer Science and Systems, University of Bologna, Italy.

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http://dx.doi.org/10.1109/EMBC.2012.6346801DOI Listing
July 2013

Lack of reduction of left ventricular mass in treated hypertension: the strong heart study.

J Am Heart Assoc 2013 Jun 6;2(3):e000144. Epub 2013 Jun 6.

Department of Translational Medical Sciences, Federico II University, Napoli, Italy.

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http://dx.doi.org/10.1161/JAHA.113.000144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698775PMC
June 2013

The role of atherectomy in the treatment of lower extremity peripheral artery disease.

BMC Surg 2012 15;12 Suppl 1:S13. Epub 2012 Nov 15.

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Via S, Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1186/1471-2482-12-S1-S13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499201PMC
May 2013

Ankle/brachial index to everyone.

BMC Surg 2012 15;12 Suppl 1:S18. Epub 2012 Nov 15.

Department of Clinical Medicine and Cardiovascular and Immunological Sciences, Federico II University, via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1186/1471-2482-12-S1-S18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499282PMC
May 2013

Reverse left ventricular remodeling after acute myocardial infarction: the prognostic impact of left ventricular global torsion.

Int J Cardiovasc Imaging 2013 Apr 22;29(4):787-95. Epub 2012 Nov 22.

Department of Medicine, Cardiovascular and Immunological Sciences, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1007/s10554-012-0159-5DOI Listing
April 2013

Antihypertensive response to combination of olmesartan and amlodipine does not depend on method and time of drug administration.

High Blood Press Cardiovasc Prev 2013 Mar 9;20(1):25-32. Epub 2013 May 9.

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University Hospital, via S. Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s40292-013-0013-4DOI Listing
March 2013

Heart rate variability and target organ damage in hypertensive patients.

BMC Cardiovasc Disord 2012 Nov 15;12:105. Epub 2012 Nov 15.

Multidisciplinary Department of Medical Sciences, Second University of Naples, Via Pansini, 5, Naples, Italy.

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http://dx.doi.org/10.1186/1471-2261-12-105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536621PMC
November 2012

Arterial stiffness is associated with carotid atherosclerosis in hypertensive patients (the Campania Salute Network).

Am J Hypertens 2012 Jul 19;25(7):739-45. Epub 2012 Apr 19.

Department of Clinical and Experimental Medicine, Federico II University Hospital, Napoli, Italy.

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http://dx.doi.org/10.1038/ajh.2012.38DOI Listing
July 2012

Lifestyle-related risk factors, smoking status and cardiovascular disease.

High Blood Press Cardiovasc Prev 2012 Jun;19(2):85-92

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy.

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http://dx.doi.org/10.2165/11632140-000000000-00000DOI Listing
June 2012

Statins and the elderly: recent evidence and current indications.

Aging Clin Exp Res 2012 Jun;24(3 Suppl):47-55

Department of Clinical Medicine and Cardiovascular and Immunology Sciences, University of Naples Federico II, via Pansini 5, 80131 Napoli, Italy.

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June 2012

Classes of antihypertensive medications and blood pressure control in relation to metabolic risk factors.

J Hypertens 2012 Jan;30(1):188-93

Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0b013e32834e1edaDOI Listing
January 2012

A Polymorphism within the Promoter of the Dopamine Receptor D1 (DRD1 -48A/G) Associates with Impaired Kidney Function in White Hypertensive Patients.

Transl Med UniSa 2012 Jan 18;2:10-9. Epub 2012 Jan 18.

Department of Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Federico II University, Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728780PMC
January 2012

Initial left-ventricular mass predicts probability of uncontrolled blood pressure in arterial hypertension.

J Hypertens 2011 Apr;29(4):803-8

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, and Department of Clinical and Experimental Medicine, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0b013e328343ce32DOI Listing
April 2011

Effects of nutraceuticals on prevalence of metabolic syndrome and on calculated Framingham Risk Score in individuals with dyslipidemia.

J Hypertens 2010 Jul;28(7):1482-7

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0b013e3283395208DOI Listing
July 2010

Nutraceuticals for treatment of high blood pressure values in patients with metabolic syndrome.

High Blood Press Cardiovasc Prev 2009 Dec 3;16(4):177-82. Epub 2013 Jan 3.

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Via Sergio Pansini 5, bld 2-, 80131, Naples, Italy.

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http://dx.doi.org/10.2165/11530420-000000000-00000DOI Listing
December 2009

Insufficient control of blood pressure and incident diabetes.

Diabetes Care 2009 May 17;32(5):845-50. Epub 2009 Feb 17.

Department of Clinical Medicine, Cardiovascular, and Immunological Sciences, Federico II University-Naples, Naples, Italy.

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http://dx.doi.org/10.2337/dc08-1881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671117PMC
May 2009

Smoking selectively accelerates carotid atherosclerosis in hypertensive patients.

High Blood Press Cardiovasc Prev 2008 Oct 22;15(4):269-73. Epub 2013 Jan 22.

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Via S. Pansini n. 5, 80131, Naples, Italy.

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http://dx.doi.org/10.2165/0151642-200815040-00006DOI Listing
October 2008

Association of suboptimal blood pressure control with body size and metabolic abnormalities.

J Hypertens 2007 Nov;25(11):2296-300

Department of Internal Medicine, Cardiovascular and Immunological Pathology, Geriatrics, Cardiac Surgery, Federico II University Hospital, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0b013e3282e9a9e4DOI Listing
November 2007

[Usefulness of a telematic system and image analysis in the follow-up of high-risk patients: a new health service model].

G Ital Cardiol (Rome) 2007 Apr;8(4):246-56

Dipartimento di Medicina Clinica e Scienze Cardiovascolari, Università degli Studi "Federico II", Napoli.

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April 2007

The Pl(A1/A2) polymorphism of glycoprotein IIIa and cerebrovascular events in hypertension: increased risk of ischemic stroke in high-risk patients.

J Hypertens 2007 Mar;25(3):551-6

Department of Clinical Medicine, Cardiovascular & Immunological Sciences, Federico II University, Naples, Italy.

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http://dx.doi.org/10.1097/HJH.0b013e328013cd67DOI Listing
March 2007

An exaggerated systolic blood pressure response to exercise is associated with cardiovascular remodeling in subjects with prehypertension.

Ital Heart J 2005 Nov;6(11):886-92

Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University of Naples Federico II, School of Medicine, Naples, Italy.

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November 2005

The use of a telematic connection for the follow-up of hypertensive patients improves the cardiovascular prognosis.

J Hypertens 2005 Jul;23(7):1417-23

Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche. Università degli studi Federico II, Napoli, Italy.

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July 2005

The Glu27 allele of the beta2 adrenergic receptor increases the risk of cardiac hypertrophy in hypertension.

J Hypertens 2004 Nov;22(11):2117-22

Department of Medicina Clinica, Scienze Cardiovascolari ed Immunologiche, Federico II University, Naples, Italy.

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November 2004