Publications by authors named "Raffaele Geremia"

43Publications

Overactive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve.

Cell Death Dis 2017 10 5;8(10):e3085. Epub 2017 Oct 5.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome 00133, Italy.

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http://dx.doi.org/10.1038/cddis.2017.496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682662PMC
October 2017

Effect Of Microgravity On Aromatase Expression In Sertoli Cells.

Sci Rep 2017 06 14;7(1):3469. Epub 2017 Jun 14.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133, Rome, Italy.

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http://dx.doi.org/10.1038/s41598-017-02018-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471225PMC
June 2017

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.

Dev Cell 2017 04 30;41(1):82-93.e4. Epub 2017 Mar 30.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy; Laboratories of Neuroembryology, Fondazione Santa Lucia IRCCS, 00143 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392497PMC
April 2017

Type 2 cannabinoid receptor contributes to the physiological regulation of spermatogenesis.

FASEB J 2016 Apr 15;30(4):1453-63. Epub 2015 Dec 15.

*Department of Biomedicine and Prevention, Section of Anatomy, University of Rome "Tor Vergata," Rome, Italy; and Laboratory of Neuroembryology, Fondazione Santa Lucia, Rome, Italy

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http://dx.doi.org/10.1096/fj.15-279034DOI Listing
April 2016

The endocannabinoid system and spermatogenesis.

Front Endocrinol (Lausanne) 2013 Dec 16;4:192. Epub 2013 Dec 16.

Section of Anatomy, Department of Biomedicine and Prevention, University of Rome "Tor Vergata" , Rome , Italy.

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http://dx.doi.org/10.3389/fendo.2013.00192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864102PMC
December 2013

The faah gene is the first direct target of estrogen in the testis: role of histone demethylase LSD1.

Cell Mol Life Sci 2012 Dec 17;69(24):4177-90. Epub 2012 Jul 17.

Department of Public Health and Cellular Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1007/s00018-012-1074-6DOI Listing
December 2012

Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells.

Nucleic Acids Res 2011 Jul 25;39(12):4961-74. Epub 2011 Feb 25.

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome, 00133 Rome, Italy.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkr085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130265PMC
July 2011

Ablation of the Sam68 gene impairs female fertility and gonadotropin-dependent follicle development.

Hum Mol Genet 2010 Dec 29;19(24):4886-94. Epub 2010 Sep 29.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://hmg.oxfordjournals.org/content/19/24/4886.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddq422
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http://dx.doi.org/10.1093/hmg/ddq422DOI Listing
December 2010

Differential contribution of the MTOR and MNK pathways to the regulation of mRNA translation in meiotic and postmeiotic mouse male germ cells.

Biol Reprod 2010 Oct 23;83(4):607-15. Epub 2010 Jun 23.

Section of Anatomy, Department of Public Health and Cell Biology, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1095/biolreprod.110.085050DOI Listing
October 2010

Expression of stemness markers in mouse parthenogenetic-diploid blastocysts is influenced by slight variation of activation protocol adopted.

In Vitro Cell Dev Biol Anim 2010 Jul 8;46(7):619-23. Epub 2010 Apr 8.

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://link.springer.com/10.1007/s11626-010-9312-4
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http://dx.doi.org/10.1007/s11626-010-9312-4DOI Listing
July 2010

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

J Cell Sci 2010 Mar 16;123(Pt 6):871-80. Epub 2010 Feb 16.

Department of Public Health and Cellular Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1242/jcs.057968DOI Listing
March 2010

Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin.

Nucleic Acids Res 2010 May 27;38(9):3005-18. Epub 2010 Jan 27.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1093/nar/gkq004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875014PMC
May 2010

Isolation and analyses of enriched populations of male mouse germ cells by sedimentation velocity: the centrifugal elutriation.

Methods Mol Biol 2009 ;558:299-321

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome Tor Vergata, Rome, Italy.

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http://link.springer.com/10.1007/978-1-60761-103-5_18
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http://dx.doi.org/10.1007/978-1-60761-103-5_18DOI Listing
October 2009

ATRA and KL promote differentiation toward the meiotic program of male germ cells.

Cell Cycle 2008 Dec 26;7(24):3878-88. Epub 2008 Dec 26.

Department of Public Health and Cellular Biology, University of Rome 'Tor Vergata', Rome.

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http://www.tandfonline.com/doi/abs/10.4161/cc.7.24.7262
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http://dx.doi.org/10.4161/cc.7.24.7262DOI Listing
December 2008

Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas.

J Pathol 2009 Feb;217(3):431-41

Department of Public Health and Cell Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://doi.wiley.com/10.1002/path.2471
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http://dx.doi.org/10.1002/path.2471DOI Listing
February 2009

Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.

Carcinogenesis 2008 Dec 22;29(12):2279-88. Epub 2008 Sep 22.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Rome, Italy.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgn221DOI Listing
December 2008

Dynamic expression of the RNA-binding protein Sam68 during mouse pre-implantation development.

Gene Expr Patterns 2008 May 2;8(5):311-22. Epub 2008 Feb 2.

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S1567133X0800024
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http://dx.doi.org/10.1016/j.gep.2008.01.005DOI Listing
May 2008

Potential role of Nanos3 in maintaining the undifferentiated spermatogonia population.

Dev Biol 2008 Jan 19;313(2):725-38. Epub 2007 Nov 19.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1016/j.ydbio.2007.11.011DOI Listing
January 2008

Transcriptome analysis of differentiating spermatogonia stimulated with kit ligand.

Gene Expr Patterns 2008 Jan 25;8(2):58-70. Epub 2007 Oct 25.

Dipartimento di Sanita' Pubblica e Biologia Cellulare, Universita' degli Studi di Roma Tor Vergata, via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.modgep.2007.10.007DOI Listing
January 2008

Src family kinase activity regulates adhesion, spreading and migration of pancreatic endocrine tumour cells.

Endocr Relat Cancer 2007 Mar;14(1):111-24

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Via Montpellier, 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1677/erc.1.01318DOI Listing
March 2007

The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes.

Mol Biol Cell 2006 Jan 12;17(1):14-24. Epub 2005 Oct 12.

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1091/mbc.e05-06-0548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345642PMC
January 2006

17-beta-estradiol elicits genomic and non-genomic responses in mouse male germ cells.

J Cell Physiol 2006 Jan;206(1):238-45

Department of Histology and Medical Embriology, University of Rome La Sapienza, Rome, Italy.

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http://dx.doi.org/10.1002/jcp.20454DOI Listing
January 2006

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes.

EMBO J 2004 Nov 4;23(23):4649-59. Epub 2004 Nov 4.

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1038/sj.emboj.7600448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC533041PMC
November 2004

Meiotic progression of isolated mouse spermatocytes under simulated microgravity.

Reproduction 2004 Jul;128(1):25-32

Dipartimento di Sanità Pubblica e Biologia Cellulare, Università di Roma 'Tor Vergata', Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1530/rep.1.00184DOI Listing
July 2004

Expression of the proto-oncogene c-KIT in normal and tumor tissues from colorectal carcinoma patients.

Int J Colorectal Dis 2004 Nov 6;19(6):545-53. Epub 2004 May 6.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://link.springer.com/10.1007/s00384-004-0601-9
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http://dx.doi.org/10.1007/s00384-004-0601-9DOI Listing
November 2004

Analysis of the gene expression profile of mouse male meiotic germ cells.

Gene Expr Patterns 2004 May;4(3):267-81

Dipartimento di Sanita Pubblica e Biologia Cellulare, Sezione di Anatomia, Universita di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.modgep.2003.11.003DOI Listing
May 2004

Expression of a truncated form of the c-Kit tyrosine kinase receptor and activation of Src kinase in human prostatic cancer.

Am J Pathol 2004 Apr;164(4):1243-51

Dipartimento di Sanità Pubblica e Biologia Cellulare, Facoltà di Medicina e Chirurgia, Università di Roma "Tor Vergata," Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615360PMC
http://dx.doi.org/10.1016/S0002-9440(10)63212-9DOI Listing
April 2004

Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes.

Mol Biol Cell 2004 Mar 10;15(3):1224-32. Epub 2003 Dec 10.

Dipartimento di Sanità Pubblica e Biologia Cellulare, University of Rome "Tor Vergata," 00133 Rome, Italy.

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http://dx.doi.org/10.1091/mbc.e03-09-0638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC363112PMC
March 2004

Tr-kit promotes the formation of a multimolecular complex composed by Fyn, PLCgamma1 and Sam68.

Oncogene 2003 Nov;22(54):8707-15

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome 'Tor Vergata', Rome, Italy.

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http://dx.doi.org/10.1038/sj.onc.1207016DOI Listing
November 2003

Cyclic adenosine monophosphate (cAMP) stimulation of the kit ligand promoter in sertoli cells requires an Sp1-binding region, a canonical TATA box, and a cAMP-induced factor binding to an immediately downstream GC-rich element.

Biol Reprod 2003 Dec 6;69(6):1979-88. Epub 2003 Aug 6.

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://dx.doi.org/10.1095/biolreprod.103.019471DOI Listing
December 2003

Developmental expression of BMP4/ALK3/SMAD5 signaling pathway in the mouse testis: a potential role of BMP4 in spermatogonia differentiation.

J Cell Sci 2003 Aug;116(Pt 16):3363-72

Dipartimento di Sanita' Pubblica e Biologia Cellulare, Sezione di Anatomia, Universita' di Roma Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1242/jcs.00650DOI Listing
August 2003

Prolin-rich tyrosine kinase 2 (PYK2) expression and localization in mouse testis.

Mol Reprod Dev 2003 Jul;65(3):330-5

Dipartimento di Medicina Sperimentale, II Università di Napoli, Naples, Italy.

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http://doi.wiley.com/10.1002/mrd.10297
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http://dx.doi.org/10.1002/mrd.10297DOI Listing
July 2003

Tr-kit-induced resumption of the cell cycle in mouse eggs requires activation of a Src-like kinase.

EMBO J 2002 Oct;21(20):5386-95

Department of Public Health and Cell Biology, Section of Anatomy, University of Rome Tor Vergata, Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC129085PMC
http://dx.doi.org/10.1093/emboj/cdf553DOI Listing
October 2002

Molecular genetics of male infertility: stem cell factor/c-kit system.

Am J Reprod Immunol 2002 Jul;48(1):27-33

Dipartimento di Sanita' Pubblica e Biologia Cellulare, Universita' degli Studi di Roma, Italy.

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http://dx.doi.org/10.1034/j.1600-0897.2002.01095.xDOI Listing
July 2002

Stem cell factor activates telomerase in mouse mitotic spermatogonia and in primordial germ cells.

J Cell Sci 2002 Apr;115(Pt 8):1643-9

Dipartimento di Sanita' Pubblica e Biologia Cellulare, Sezione di Anatomia, Rome, Italy.

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April 2002

The MAPK pathway triggers activation of Nek2 during chromosome condensation in mouse spermatocytes.

Development 2002 Apr;129(7):1715-27

Dipartimento di Sanità Pubblica e Biologia Cellulare, Facoltà di Medicina e Chirurgia, Università di Roma Tor Vergata, Via O. Raimondo 8, 00173 Rome, Italy.

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April 2002