Rafael de Cabo

Rafael de Cabo

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Rafael de Cabo

Rafael de Cabo

Publications by authors named "Rafael de Cabo"

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Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates.

PLoS One 2019 5;14(12):e0225911. Epub 2019 Dec 5.

Division of Cellular and Molecular Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225911PLOS
December 2019

Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice.

Nutr Healthy Aging 2019 Sep 23;5(2):111-117. Epub 2019 Sep 23.

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.3233/NHA-180059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599PMC
September 2019

Of Aging Mice and Men: Gait Speed Decline Is a Translatable Trait, With Species-Specific Underlying Properties.

J Gerontol A Biol Sci Med Sci 2019 Aug;74(9):1413-1416

Translational Gerontology Branch, National Institute on Aging, Intramural Research Program, National Institute of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glz015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696716PMC
August 2019

Maternally expressed gene 3 in metabolic programming.

Biochim Biophys Acta Gene Regul Mech 2019 Jul 1:194396. Epub 2019 Jul 1.

Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2019.06.007DOI Listing
July 2019

Frailty index as a biomarker of lifespan and healthspan: Focus on pharmacological interventions.

Mech Ageing Dev 2019 06 26;180:42-48. Epub 2019 Mar 26.

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2019.03.005DOI Listing
June 2019

Pomalidomide Reduces Ischemic Brain Injury in Rodents.

Cell Transplant 2019 Apr 16;28(4):439-450. Epub 2019 May 16.

1 The PhD Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei.

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http://dx.doi.org/10.1177/0963689719850078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628558PMC
April 2019

Yo-Yo Dieting is Better than None.

Obesity (Silver Spring) 2018 11;26(11):1673

Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.

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http://doi.wiley.com/10.1002/oby.22335
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http://dx.doi.org/10.1002/oby.22335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208150PMC
November 2018

A time to fast.

Science 2018 11;362(6416):770-775

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aau2095
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http://dx.doi.org/10.1126/science.aau2095DOI Listing
November 2018

Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice.

J Physiol 2018 Nov 21. Epub 2018 Nov 21.

Laboratory of Cardiovascular Science, National Institute on Aging/NIH, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1113/JP276824DOI Listing
November 2018

Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice.

Cell Rep 2018 11;25(8):2234-2243.e6

Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia; Aging and Alzheimers Institute, ANZAC Research Institute, Centre for Education and Research on Ageing, Concord, NSW 2139, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.10.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296764PMC
November 2018

Breaking the Ceiling of Human Maximal Life span.

J Gerontol A Biol Sci Med Sci 2018 10;73(11):1465-1471

The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.

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https://academic.oup.com/biomedgerontology/article/73/11/146
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http://dx.doi.org/10.1093/gerona/glx219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454488PMC
October 2018

Carbotoxicity-Noxious Effects of Carbohydrates.

Cell 2018 10;175(3):605-614

Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD 21224, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183097
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http://dx.doi.org/10.1016/j.cell.2018.07.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265656PMC
October 2018

Intermittent mTOR Inhibition Reverses Kidney Aging in Old Rats.

J Gerontol A Biol Sci Med Sci 2018 06;73(7):843-844

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/gly023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001901PMC
June 2018

Future directions of resveratrol research.

Nutr Healthy Aging 2018 Jun 15;4(4):287-290. Epub 2018 Jun 15.

Charles Perkins Centre, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.3233/NHA-170035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004906PMC
June 2018

Redox modulation of NQO1.

PLoS One 2018 3;13(1):e0190717. Epub 2018 Jan 3.

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190717PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752044PMC
February 2018

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance.

Cell Rep 2018 02;22(8):2133-2145

Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA; Integrative Cell Signaling and Neurobiology of Metabolism Program, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860817PMC
February 2018

Sex and Aging.

J Gerontol A Biol Sci Med Sci 2018 01;73(2):139-140

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glx221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279165PMC
January 2018

Caloric Restriction Study Design Limitations in Rodent and Nonhuman Primate Studies.

J Gerontol A Biol Sci Med Sci 2017 Dec;73(1):48-53

Translational Gerontology Branch, National Institute on Aging, Dickerson, Maryland.

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http://dx.doi.org/10.1093/gerona/glx088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861872PMC
December 2017

Caloric Restriction Research: New Perspectives on the Biology of Aging.

J Gerontol A Biol Sci Med Sci 2017 12;73(1):1-3

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glx212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279158PMC
December 2017

Health benefits of late-onset metformin treatment every other week in mice.

NPJ Aging Mech Dis 2017 20;3:16. Epub 2017 Nov 20.

Experimental Gerontology Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD 21224 USA.

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http://dx.doi.org/10.1038/s41514-017-0018-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696465PMC
November 2017

Calorie restriction in rodents: Caveats to consider.

Ageing Res Rev 2017 Oct 10;39:15-28. Epub 2017 Jun 10.

Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, Baltimore, MD 21224-6825, United States. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2017.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565679PMC
October 2017

Stem Cell Transplantation for Frailty.

J Gerontol A Biol Sci Med Sci 2017 10;72(11):1503-1504

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glx158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279163PMC
October 2017

Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.

Free Radic Biol Med 2017 09 9;110:176-187. Epub 2017 Jun 9.

Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Campus de Excelencia Internacional Agroalimentario, ceiA3, Spain.

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539908PMC
September 2017

Hexokinases link DJ-1 to the PINK1/parkin pathway.

Mol Neurodegener 2017 09 29;12(1):70. Epub 2017 Sep 29.

Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Building 35, Room 1A116, 35 Convent Drive, MSC 3707, Bethesda, MD, 20892-3707, USA.

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http://dx.doi.org/10.1186/s13024-017-0212-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622528PMC
September 2017

Influence of anaerobic and aerobic exercise on age-related pathways in skeletal muscle.

Ageing Res Rev 2017 08 6;37:39-52. Epub 2017 May 6.

Translational Gerontology Branch, National Institute on Aging, NIH, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549001PMC
August 2017

SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study.

J Gerontol A Biol Sci Med Sci 2017 Jul;72(7):870-876

Centre for Education and Research on Ageing and the Ageing and Alzheimers Institute, University of Sydney and Concord Hospital, New South Wales, Australia.

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http://dx.doi.org/10.1093/gerona/glx018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279142PMC
July 2017

A Comparison of Two Mouse Frailty Assessment Tools.

J Gerontol A Biol Sci Med Sci 2017 Jul;72(7):904-909

Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research and Sydney Medical School, University of Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1093/gerona/glx009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861875PMC
July 2017

The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct.

J Bone Miner Res 2017 Mar 3;32(3):560-574. Epub 2016 Nov 3.

Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases, University of Arkansas for Medical Sciences, and the Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.

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http://dx.doi.org/10.1002/jbmr.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340621PMC
March 2017

Involvement of c-Jun N-Terminal Kinase in TNF-α-Driven Remodeling.

Am J Respir Cell Mol Biol 2017 03;56(3):393-401

1 Department of Respiratory Medicine, School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands.

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http://dx.doi.org/10.1165/rcmb.2015-0195OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455592PMC
March 2017

17α-Estradiol: A Novel Therapeutic Intervention to Target Age-related Chronic Inflammation.

J Gerontol A Biol Sci Med Sci 2017 01 31;72(1):1-2. Epub 2016 Mar 31.

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glw041DOI Listing
January 2017

Animal models of frailty: current applications in clinical research.

Clin Interv Aging 2016 26;11:1519-1529. Epub 2016 Oct 26.

Department of Pharmacology, Dalhousie University, Halifax, NS, Canada.

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http://dx.doi.org/10.2147/CIA.S105714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089820PMC
January 2017

Spermidine to the rescue for an aging heart.

Nat Med 2016 12;22(12):1389-1390

Centro Andaluz de Biología del Desarrollo, CABD-CSIC, CIBERER, Instituto Carlos III, Universidad Pablo de Olavide, Sevilla, Spain.

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http://dx.doi.org/10.1038/nm.4243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853099PMC
December 2016

Nutritional strategies to optimise cognitive function in the aging brain.

Ageing Res Rev 2016 11 26;31:80-92. Epub 2016 Jun 26.

Charles Perkins Centre, University of Sydney, Sydney 2006 Australia; Aging and Alzheimers Institute, ANZAC Research Institute, Concord Clinical School/Sydney Medical School, Concord, 2139 Australia. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2016.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035589PMC
November 2016

Amniotic Epithelial Cells: A New Tool to Combat Aging and Age-Related Diseases?

Front Cell Dev Biol 2016 22;4:135. Epub 2016 Nov 22.

Faculty of Veterinary Medicine, University of Teramo Teramo, Italy.

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http://dx.doi.org/10.3389/fcell.2016.00135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118838PMC
November 2016

Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation.

Free Radic Biol Med 2016 10 8;99:225-233. Epub 2016 Aug 8.

Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, 251 Bayview Blvd., Suite 100, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107118PMC
October 2016

Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity.

Cancer Cell 2016 07;30(1):136-146

Longevity Institute, Leonard Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1016/j.ccell.2016.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388544PMC
July 2016

Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie-restricted mice.

Aging Cell 2016 06 8;15(3):477-87. Epub 2016 Feb 8.

Departamento de Biología Celular, Fisiología e Inmunología, Campus de Excelencia Internacional Agroalimentario, ceiA3, Universidad de Córdoba, Córdoba, Spain.

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http://dx.doi.org/10.1111/acel.12451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854917PMC
June 2016

Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence.

Aging Cell 2016 06 17;15(3):572-81. Epub 2016 Mar 17.

Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1111/acel.12469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854919PMC
June 2016

Mitochondrial permeabilization without caspase activation mediates the increase of basal apoptosis in cells lacking Nrf2.

Free Radic Biol Med 2016 06 22;95:82-95. Epub 2016 Mar 22.

Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Campus de Excelencia Internacional Agroalimentario, ceiA3, Spain.

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906443PMC
June 2016

Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging.

J Gerontol A Biol Sci Med Sci 2016 May 4;71(5):571-7. Epub 2015 May 4.

Departments of Clinical Pharmacology and Aged Care, Royal North Shore Hospital and Kolling Institute of Medical Research, St Leonards, NSW, Australia. Sydney Medical School, University of Sydney, NSW, Australia.

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http://dx.doi.org/10.1093/gerona/glv046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007735PMC
May 2016

Pharmacological Strategies to Retard Cardiovascular Aging.

Circ Res 2016 05;118(10):1626-42

From the Experimental Gerontology Section, Translational Gerontology Branch (I.A., C.D.G., M.B., R.d.C.) and Laboratory of Cardiovascular Science (E.G.L.), National Institute on Aging, National Institutes of Health, Baltimore, MD; Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy (C.D.G.); and Reynolds Oklahoma Center on Aging, Department of Geriatric Medicine, University of Oklahoma Health Science Center, Oklahoma City, OK (A.C., Z.U.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.307475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894351PMC
May 2016

Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice.

Behav Brain Res 2016 Mar 14;301:1-9. Epub 2015 Dec 14.

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2015.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823003PMC
March 2016

The impact of low-protein high-carbohydrate diets on aging and lifespan.

Cell Mol Life Sci 2016 Mar 30;73(6):1237-52. Epub 2015 Dec 30.

Charles Perkins Centre, University of Sydney, Sydney, 2006, Australia.

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http://dx.doi.org/10.1007/s00018-015-2120-yDOI Listing
March 2016

Metformin: A Hopeful Promise in Aging Research.

Cold Spring Harb Perspect Med 2016 Mar 1;6(3):a025932. Epub 2016 Mar 1.

Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, Maryland 21224.

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http://dx.doi.org/10.1101/cshperspect.a025932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772077PMC
March 2016

The effect of ageing on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 rats.

Fundam Clin Pharmacol 2016 Feb 9;30(1):23-34. Epub 2015 Nov 9.

Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/fcp.12157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976487PMC
February 2016

Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type.

Exp Gerontol 2016 Jan 23;73:95-106. Epub 2015 Nov 23.

Kolling Institute of Medical Research, Sydney, NSW, Australia; Royal North Shore Hospital, Sydney, NSW, Australia; Sydney Medical School, University of Sydney, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2015.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976491PMC
January 2016

miR-27b inhibits LDLR and ABCA1 expression but does not influence plasma and hepatic lipid levels in mice.

Atherosclerosis 2015 Dec;243(2):499-509

Section of Comparative Medicine, Department of Pathology, Program in Integrative Cell Signaling and Neurobiology of Metabolism and the Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975922PMC
December 2015

Translational strategies in aging and age-related disease.

Nat Med 2015 Dec;21(12):1395-9

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/nm.4004DOI Listing
December 2015

Energy - A Hallmark of Physical Function.

J Gerontol A Biol Sci Med Sci 2015 Nov 13;70(11):1333. Epub 2015 Aug 13.

Experimental Gerontology Section, National Institute on Aging, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glv131DOI Listing
November 2015

Circular RNAs in monkey muscle: age-dependent changes.

Aging (Albany NY) 2015 Nov;7(11):903-10

Laboratory of Genetics, National Institute on Aging-Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694061PMC
http://dx.doi.org/10.18632/aging.100834DOI Listing
November 2015

The influence of dietary fat source on liver and skeletal muscle mitochondrial modifications and lifespan changes in calorie-restricted mice.

Biogerontology 2015 Oct 10;16(5):655-70. Epub 2015 Apr 10.

Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, Campus Rabanales, Edificio Severo Ochoa, 3ª planta, Campus de Excelencia Internacional Agroalimentario, ceiA3, 14014, Córdoba, Spain,

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http://dx.doi.org/10.1007/s10522-015-9572-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555094PMC
October 2015

Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.

Mol Endocrinol 2015 Oct 19;29(10):1498-509. Epub 2015 Aug 19.

Division of Endocrinology and Metabolism (H.-N.K., L.H., S.I., H.Z., C.A.O., S.C.M., M.A.), Center for Osteoporosis and Metabolic Bone Diseases, University of Arkansas for Medical Sciences and the Central Arkansas Veterans Healthcare System, Little Rock, Arkansas 72205; and Translational Gerontology Branch (R.d.C.), National Institute on Aging, Baltimore, Maryland 21224.

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http://dx.doi.org/10.1210/me.2015-1133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588729PMC
October 2015

Two-Year Trial of Human Caloric Restriction.

J Gerontol A Biol Sci Med Sci 2015 Sep 17;70(9):1095-6. Epub 2015 Jul 17.

Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glv100DOI Listing
September 2015

The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats.

Exp Gerontol 2015 Jul 22;67:54-61. Epub 2015 Apr 22.

Laboratory of Ageing and Pharmacology, Kolling Institute of Medical Research, Sydney, NSW, Australia; Depts of Clinical Pharmacology and Aged Care, Royal North Shore Hosp, Sydney, NSW, Australia; Sydney Medical School, Univ of Sydney, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2015.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854160PMC
July 2015

GH Receptor Deficiency in Ecuadorian Adults Is Associated With Obesity and Enhanced Insulin Sensitivity.

J Clin Endocrinol Metab 2015 Jul 18;100(7):2589-96. Epub 2015 May 18.

Universidad San Francisco de Quito (J.G.-A., E.T.), Quito, Ecuador; Instituto de Endocrinologia, Metabolismo y Repróduccion (J.G.-A., A.L.R., M.G.-A., C.G., P.P., L.N., J.S.), Quito Ecuador; University of Florida College of Medicine (A.L.R.), Gainesville, Florida 32608; Davis School of Gerontology (P.B., S.D.B., V.D.L.), University of Southern California, Los Angeles, California 90089; Experimental Gerontology Section (I.A., R.D.C.), Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224; and Longevity Institute (V.D.L.), University of Southern California, Los Angeles, California 90089.

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http://dx.doi.org/10.1210/jc.2015-1678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490304PMC
July 2015

Macronutrients and caloric intake in health and longevity.

J Endocrinol 2015 Jul 28;226(1):R17-28. Epub 2015 May 28.

Charles Perkins CentreBuilding D17, University of Sydney, Sydney, New South Wales 2006, AustraliaANZAC Research Institute and the Ageing and Alzheimers InstituteCentre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, New South Wales, AustraliaSchool of Biological SciencesUniversity of Sydney, Sydney, New South Wales, AustraliaTranslational Gerontology BranchNational Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USAFaculty of Veterinary ScienceUniversity of Sydney, Sydney, New South Wales, Australia Charles Perkins CentreBuilding D17, University of Sydney, Sydney, New South Wales 2006, AustraliaANZAC Research Institute and the Ageing and Alzheimers InstituteCentre for Education and Research on Ageing, Concord Hospital, University of Sydney, Sydney, New South Wales, AustraliaSchool of Biological SciencesUniversity of Sydney, Sydney, New South Wales, AustraliaTranslational Gerontology BranchNational Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USAFaculty of Veterinary ScienceUniversity of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1530/JOE-15-0173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490104PMC
July 2015

Factors that Impact on Interrater Reliability of the Mouse Clinical Frailty Index.

J Gerontol A Biol Sci Med Sci 2015 Jun 2;70(6):694-5. Epub 2015 Apr 2.

Experimental Gerontology Section, National Institute on Aging, Baltimore, Maryland.

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http://dx.doi.org/10.1093/gerona/glv032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447804PMC
June 2015

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice.

Cell Rep 2015 Jun 28;11(10):1529-34. Epub 2015 May 28.

Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia; Ageing and Alzheimers Institute and ANZAC Research Institute, Concord Hospital, University of Sydney, Sydney, NSW 2139, Australia.

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http://dx.doi.org/10.1016/j.celrep.2015.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472496PMC
June 2015

Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo.

Aging (Albany NY) 2015 Apr;7(4):233-40

Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429088PMC
http://dx.doi.org/10.18632/aging.100732DOI Listing
April 2015

Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro.

Aging (Albany NY) 2015 Mar;7(3):152-66

Experimental Gerontology Section, Translational Gerontology Branch, NIA/NIH, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394727PMC
http://dx.doi.org/10.18632/aging.100719DOI Listing
March 2015