Publications by authors named "Rafael Simó"

100Publications

Neuropathic damage in the diabetic eye: clinical implications.

Curr Opin Pharmacol 2020 Sep 12;55:1-7. Epub 2020 Sep 12.

Unit of Endocrinology, Diabetes and Metabolism, S. Giovanni Calibita, Fate Bene Fratelli Hospital, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1016/j.coph.2020.08.013DOI Listing
September 2020

Beneficial Effects of Glucagon-Like Peptide-1 (GLP-1) in Diabetes-Induced Retinal Abnormalities: Involvement of Oxidative Stress.

Antioxidants (Basel) 2020 Sep 10;9(9). Epub 2020 Sep 10.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute (VHIR), 08035 Barcelona, Spain.

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http://dx.doi.org/10.3390/antiox9090846DOI Listing
September 2020

Bidirectional relationship between diabetes and pulmonary function: a systematic review and meta-analysis.

Diabetes Metab 2020 Sep 1. Epub 2020 Sep 1.

Endocrinology and Nutrition Department, Hospital Universitari Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), Institut de Recerca Biomèdica de Lleida (IRBLleida), Universitat de Lleida, Lleida, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.diabet.2020.08.003DOI Listing
September 2020

Effect of Type 2 Diabetes Mellitus on the Hypoxia-Inducible Factor 1-Alpha Expression. Is There a Relationship with the Clock Genes?

J Clin Med 2020 Aug 13;9(8). Epub 2020 Aug 13.

Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism (ODIM) Research Group, IRBLleida, University of Lleida, 25198 Lleida, Spain.

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http://dx.doi.org/10.3390/jcm9082632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465909PMC
August 2020

Sex hormone-binding globulin overexpression protects against high-fat diet-induced obesity in transgenic male mice.

J Nutr Biochem 2020 Aug 12;85:108480. Epub 2020 Aug 12.

Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jnutbio.2020.108480DOI Listing
August 2020

Effect of Topical Administration of Somatostatin on Retinal Inflammation and Neurodegeneration in an Experimental Model of Diabetes.

J Clin Med 2020 Aug 10;9(8). Epub 2020 Aug 10.

Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERdem), ISCIII, 28029 Madrid, Spain.

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http://dx.doi.org/10.3390/jcm9082579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463891PMC
August 2020

Utility of Insulin Resistance in Estimating Cardiovascular Risk in Subjects with Type 1 Diabetes According to the Scores of the Steno Type 1 Risk Engine.

J Clin Med 2020 Jul 11;9(7). Epub 2020 Jul 11.

Department of Endocrinology and Nutrition, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Parc Taulí 1, 08208 Sabadell, Spain.

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http://dx.doi.org/10.3390/jcm9072192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409001PMC
July 2020

Caffeine Upregulates Hepatic Sex Hormone-Binding Globulin Production by Increasing Adiponectin Through AKT/FOXO1 Pathway in White Adipose Tissue.

Mol Nutr Food Res 2020 Sep 23;64(17):e1901253. Epub 2020 Jul 23.

Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, 08035, Spain.

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http://dx.doi.org/10.1002/mnfr.201901253DOI Listing
September 2020

Diabetic retinopathy: looking beyond the eyes.

Diabetologia 2020 Aug 18;63(8):1662-1664. Epub 2020 Jun 18.

Section of Diabetes and Metabolic Diseases, Department of Medicine, University of Padova, Padova, Italy.

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http://dx.doi.org/10.1007/s00125-020-05195-4DOI Listing
August 2020

A Translational In Vivo and In Vitro Metabolomic Study Reveals Altered Metabolic Pathways in Red Blood Cells of Type 2 Diabetes.

J Clin Med 2020 May 27;9(6). Epub 2020 May 27.

Medical Molecular Imaging Research Group, Vall d'Hebron Research Institute, CIBBIM-Nanomedicine, and Autonomous University of Barcelona, Passeig de la Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.3390/jcm9061619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355709PMC
May 2020

Impact of antidiabetic agents on dementia risk: A Bayesian network meta-analysis.

Metabolism 2020 08 22;109:154265. Epub 2020 May 22.

Endocrinology and Nutrition Department, Hospital Universitari Vall d'Hebron, Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Passeig de la Vall d'Hebron, 119, 08035 Barcelona, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2020.154265DOI Listing
August 2020

Understanding multifactorial brain changes in type 2 diabetes: a biomarker perspective.

Lancet Neurol 2020 08 20;19(8):699-710. Epub 2020 May 20.

Department of Neurology and Alzheimer Center, VU University Medical Center Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1016/S1474-4422(20)30139-3DOI Listing
August 2020

Looking for solutions to lung dysfunction in type 2 diabetes.

Ann Transl Med 2020 Apr;8(8):521

Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.

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http://dx.doi.org/10.21037/atm.2020.03.225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214897PMC
April 2020

Effect of Subcutaneous Insulin on Spirometric Maneuvers in Patients with Type 1 Diabetes: A Case-Control Study.

J Clin Med 2020 Apr 25;9(5). Epub 2020 Apr 25.

Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica de Lleida (IRBLleida), University of Lleida, 25198 Lleida, Spain.

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http://dx.doi.org/10.3390/jcm9051249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287574PMC
April 2020

Alteration of the Mitochondrial Effects of Ceria Nanoparticles by Gold: An Approach for the Mitochondrial Modulation of Cells Based on Nanomedicine.

Nanomaterials (Basel) 2020 Apr 13;10(4). Epub 2020 Apr 13.

Medical Molecular Imaging Research Group, Vall d'Hebron Research Institute, CIBBIM- Nanomedicine, Universitat Autònoma de Barcelona (UAB) and Biomedical Imaging Group, Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 08035 Barcelona, Spain.

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http://dx.doi.org/10.3390/nano10040744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221686PMC
April 2020

Effect of Glucose Improvement on Nocturnal Sleep Breathing Parameters in Patients with Type 2 Diabetes: The Candy Dreams Study.

J Clin Med 2020 Apr 4;9(4). Epub 2020 Apr 4.

Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism (ODIM) research group, IRBLleida, University of Lleida, 25198 Lleida, Spain.

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http://dx.doi.org/10.3390/jcm9041022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230160PMC
April 2020

Screening for diabetic retinopathy: new perspectives and challenges.

Lancet Diabetes Endocrinol 2020 04 27;8(4):337-347. Epub 2020 Feb 27.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain; Department of Medicine and Endocrinology, Autonomous University of Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(19)30411-5DOI Listing
April 2020

Is it time to change the management of permanent postsurgical hypoparathyroidism?

Endocrinol Diabetes Nutr 2020 01 9;67(1):1-3. Epub 2019 Dec 9.

Diabetes Research and Metabolism Unit, Institut de Recerca Hospital Univesitari Vall d'Hebron, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.endinu.2019.10.002DOI Listing
January 2020

Sympathetic Hyperactivity and Sleep Disorders in Individuals With Type 2 Diabetes.

Front Endocrinol (Lausanne) 2019 1;10:752. Epub 2019 Nov 1.

Endocrinology and Nutrition Department, Institut de Recerca Biomèdica de Lleida (IRBLleida), Hospital Universitari Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), Universitat de Lleida (UdL), Lleida, Spain.

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http://dx.doi.org/10.3389/fendo.2019.00752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839128PMC
November 2019

Characteristics of atheromatosis in the prediabetes stage: a cross-sectional investigation of the ILERVAS project.

Cardiovasc Diabetol 2019 11 15;18(1):154. Epub 2019 Nov 15.

Endocrinology and Nutrition Department, University Hospital Arnau de Vilanova, Obesity, Diabetes and Metabolism (ODIM) research Group, IRBLleida, University of Lleida, Lleida, Spain.

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http://dx.doi.org/10.1186/s12933-019-0962-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857207PMC
November 2019

Combining metabolic profiling of plasma and faeces as a fingerprint of insulin resistance in obesity.

Clin Nutr 2020 Jul 25;39(7):2292-2300. Epub 2019 Oct 25.

CIBER de la Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Diabetes, Endocrinology and Nutrition (UDEN), Institut d'Investigació Biomédica de Girona (IDIBGI), Girona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.10.022DOI Listing
July 2020

Metabolic Fingerprint of Acromegaly and its Potential Usefulness in Clinical Practice.

J Clin Med 2019 Sep 26;8(10). Epub 2019 Sep 26.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute and CIBERDEM (ISCIII), Universidad Autónoma de Barcelona, 08035 Barcelona, Spain.

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http://dx.doi.org/10.3390/jcm8101549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832216PMC
September 2019

δ Opioid Receptor Agonism Preserves the Retinal Pigmented Epithelial Cell Tight Junctions and Ameliorates the Retinopathy in Experimental Diabetes.

Invest Ophthalmol Vis Sci 2019 09;60(12):3842-3853

Renal Pathophysiology Laboratory, Investigation on Diabetes Complications, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, Brazil.

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http://dx.doi.org/10.1167/iovs.19-26761DOI Listing
September 2019

Diabetic Retinopathy in the Context of Patients with Diabetes.

Ophthalmic Res 2019 24;62(4):211-217. Epub 2019 May 24.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain,

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https://www.karger.com/Article/FullText/499541
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http://dx.doi.org/10.1159/000499541DOI Listing
January 2020

Topical Treatment With Brimonidine and Somatostatin Causes Retinal Vascular Dilation in Patients With Early Diabetic Retinopathy From the EUROCONDOR.

Invest Ophthalmol Vis Sci 2019 05;60(6):2257-2262

Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Universitari Vall d'Hebron (VHIR), Barcelona, Spain.

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http://dx.doi.org/10.1167/iovs.18-26487DOI Listing
May 2019

Lung function measurements in the prediabetes stage: data from the ILERVAS Project.

Acta Diabetol 2019 Sep 15;56(9):1005-1012. Epub 2019 Apr 15.

Endocrinology and Nutrition Department, Hospital Universitari Vall d'Hebron, Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.

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http://link.springer.com/10.1007/s00592-019-01333-6
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http://dx.doi.org/10.1007/s00592-019-01333-6DOI Listing
September 2019

Glutamate interactions with obesity, insulin resistance, cognition and gut microbiota composition.

Acta Diabetol 2019 May 19;56(5):569-579. Epub 2019 Mar 19.

Department of Diabetes, Endocrinology and Nutrition, Hospital of Girona "Dr Josep Trueta", Institut d'Investigació Biomèdica de Girona (IDIBGI), Avinguda de França s/n, 17007, Girona, Spain.

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http://dx.doi.org/10.1007/s00592-019-01313-wDOI Listing
May 2019

Effect of Glucose Improvement on Spirometric Maneuvers in Patients With Type 2 Diabetes: The Sweet Breath Study.

Diabetes Care 2019 04 31;42(4):617-624. Epub 2019 Jan 31.

Endocrinology and Nutrition Department, Hospital Universitari Arnau de Vilanova, Obesity, Diabetes and Metabolism Research Group (ODIM), Institut de Recerca Biomèdica de Lleida (IRBLleida), and Universitat de Lleida, Lleida, Catalonia, Spain

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http://dx.doi.org/10.2337/dc18-1948DOI Listing
April 2019

Adipocyte MTERF4 regulates non-shivering adaptive thermogenesis and sympathetic-dependent glucose homeostasis.

Biochim Biophys Acta Mol Basis Dis 2019 06 26;1865(6):1298-1312. Epub 2019 Jan 26.

Laboratory of Metabolism and Obesity, Vall d'Hebron - Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain; CIBERDEM, CIBER on Diabetes and Associated Metabolic Diseases, Instituto de Salud Carlos III, Barcelona, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439193002
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http://dx.doi.org/10.1016/j.bbadis.2019.01.025DOI Listing
June 2019

Usefulness of Eye Fixation Assessment for Identifying Type 2 Diabetic Subjects at Risk of Dementia.

J Clin Med 2019 Jan 8;8(1). Epub 2019 Jan 8.

Diabetes and Metabolism Research Unit. Vall d'Hebron Research Institute, 08035 Barcelona, Spain.

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http://dx.doi.org/10.3390/jcm8010059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352169PMC
January 2019

Sex Hormone-Binding Globulin Expression Correlates With Acetyl-Coenzyme A Carboxylase and Triglyceride Content in Human Liver.

J Clin Endocrinol Metab 2019 05;104(5):1500-1507

Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca, Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain.

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http://dx.doi.org/10.1210/jc.2018-00740DOI Listing
May 2019

Effects of Topically Administered Neuroprotective Drugs in Early Stages of Diabetic Retinopathy: Results of the EUROCONDOR Clinical Trial.

Diabetes 2019 02 2;68(2):457-463. Epub 2018 Nov 2.

Association for Innovation and Biomedical Research on Light and Image (AIBILI), Coimbra, Portugal, and Faculty of Medicine, University of Coimbra, Ophthalmology Department, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db18
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http://dx.doi.org/10.2337/db18-0682DOI Listing
February 2019

The ERM Complex: A New Player Involved in Diabetes-induced Vascular Leakage.

Curr Med Chem 2020 ;27(18):3012-3022

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.2174/0929867325666181016162327DOI Listing
August 2020

Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue.

FASEB J 2019 02 2;33(2):2343-2358. Epub 2018 Oct 2.

Laboratory of Metabolism and Obesity, Vall d'Hebron-Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain.

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https://www.fasebj.org/doi/10.1096/fj.201800310R
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http://dx.doi.org/10.1096/fj.201800310RDOI Listing
February 2019

Comment on: "Glucagon-like peptide-1 receptor expression in the human eye".

Diabetes Obes Metab 2019 02 2;21(2):446-447. Epub 2018 Oct 2.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/dom.13521DOI Listing
February 2019

Assessment of advanced glycation end-products as a biomarker of diabetic outcomes.

Endocrinol Diabetes Nutr 2018 Nov 2;65(9):540-545. Epub 2018 Aug 2.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute Barcelona, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Spain.

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http://dx.doi.org/10.1016/j.endinu.2018.06.003DOI Listing
November 2018

Neurodegeneration in diabetic retinopathy: does it really matter?

Diabetologia 2018 09 20;61(9):1902-1912. Epub 2018 Jul 20.

Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/s00125-018-4692-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096638PMC
September 2018

Author Correction: Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox.

Sci Rep 2018 Mar 19;8(1):5046. Epub 2018 Mar 19.

Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR). Universitat Autònoma de Barcelona and Biomedical Network Research Centre on Diabetes and Metabolic Diseases (CIBERDEM, ISCIII), Barcelona, Spain.

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http://dx.doi.org/10.1038/s41598-018-23159-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859090PMC
March 2018

Somatostatin and diabetic retinopathy: an evolving story.

Endocrine 2018 04 20;60(1):1-3. Epub 2018 Feb 20.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.1007/s12020-018-1561-0DOI Listing
April 2018

Silymarin prevents diabetes-induced hyperpermeability in human retinal endothelial cells.

Endocrinol Diabetes Nutr 2018 Apr 13;65(4):200-205. Epub 2018 Feb 13.

Diabetes and Metabolism Research Unit. Vall d'Hebron Research Institute. Universitat Autònoma de Barcelona, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.endinu.2017.12.004DOI Listing
April 2018

Association of HMGB1 with oxidative stress markers and regulators in PDR.

Mol Vis 2017 5;23:853-871. Epub 2017 Dec 5.

Diabetes and Metabolism Research Unit and CIBERDEM (ISCIII).Vall d'Hebron Research Institute. Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723152PMC
May 2018

Response to oral sucrosomial iron supplementation in patients undergoing bariatric surgery. The BARI-FER study.

Endocrinol Diabetes Nutr 2018 Jan 7;65(1):17-20. Epub 2017 Dec 7.

Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Spain; Endocrinology and Nutrition Department, Vall d'Hebron University Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.endinu.2017.10.007DOI Listing
January 2018

Semaglutide, reduction in glycated haemoglobin and the risk of diabetic retinopathy.

Diabetes Obes Metab 2018 04 8;20(4):889-897. Epub 2018 Jan 8.

Department of Ophthalmology, Rigshospitalet and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

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http://doi.wiley.com/10.1111/dom.13172
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http://dx.doi.org/10.1111/dom.13172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888154PMC
April 2018

Mechanisms of retinal neuroprotection of calcium dobesilate: therapeutic implications.

Neural Regen Res 2017 Oct;12(10):1620-1622

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, CIBERDEM (Instituto de Salud Carlos III), Barcelona, Spain.

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http://dx.doi.org/10.4103/1673-5374.217333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696841PMC
October 2017

A compartmentalized microfluidic chip with crisscross microgrooves and electrophysiological electrodes for modeling the blood-retinal barrier.

Lab Chip 2017 12;18(1):95-105

Institut de Microelectrònica de Barcelona, IMB-CNM (CSIC), 08193, Bellaterra, Barcelona, Spain.

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http://dx.doi.org/10.1039/c7lc00795gDOI Listing
December 2017

Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox.

Sci Rep 2017 09 25;7(1):12284. Epub 2017 Sep 25.

Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR). Universitat Autònoma de Barcelona and Biomedical Network Research Centre on Diabetes and Metabolic Diseases (CIBERDEM, ISCIII), Barcelona, Spain.

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http://dx.doi.org/10.1038/s41598-017-12509-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612985PMC
September 2017

Serum Surfactant Protein D as a Biomarker for Measuring Lung Involvement in Obese Patients With Type 2 Diabetes.

J Clin Endocrinol Metab 2017 11;102(11):4109-4116

Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, 28029 Madrid, Spain.

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http://academic.oup.com/jcem/article/102/11/4109/4157553
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http://dx.doi.org/10.1210/jc.2017-00913DOI Listing
November 2017

Pulmonary Function and Sleep Breathing: Two New Targets for Type 2 Diabetes Care.

Endocr Rev 2017 12;38(6):550-573

Respiratory Department, Hospital Universitari Arnau de Vilanova-Santa María, Institut de Recerca Biomédica de Lleida, Universitat de Lleida, Spain.

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http://dx.doi.org/10.1210/er.2017-00173DOI Listing
December 2017

Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes.

N Engl J Med 2017 12 13;377(24):2337-2348. Epub 2017 Sep 13.

From the University of Colorado Denver, Aurora (S.K.G.); the University of California at San Diego, San Diego (R.R.H.); Lexicon Pharmaceuticals, The Woodlands (P.B., D.G.-P., P.L., P.S.), the University of Texas Southwestern Medical Center, Dallas (D.K.M.), and Baylor College of Medicine and Texas Children's Hospital, Houston (J.A.K.) - all in Texas; the Diabetes Research Center, University of North Carolina School of Medicine, Durham (J.B.B.); the University of Leicester and University Hospitals of Leicester NHS Trust, Leicester, United Kingdom (M.J.D.); the University of Sydney, Sydney (G.R.F.); University Campus Bio-Medico of Rome, Rome (P.P.); Vall d'Hebron Research Institute, Barcelona, and CIBERDEM-Instituto de Salud Carlos III, Madrid (R.S.); Diabetes Center Auf der Bult, Hannover Medical School, Hannover, Germany (T.D.); and the University of Southern California, Los Angeles (A.P.).

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http://dx.doi.org/10.1056/NEJMoa1708337DOI Listing
December 2017

Calcium dobesilate prevents the oxidative stress and inflammation induced by diabetes in the retina of db/db mice.

J Diabetes Complications 2017 Oct 26;31(10):1481-1490. Epub 2017 Jul 26.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jdiacomp.2017.07.009DOI Listing
October 2017

Diabetic Retinopathy Phenotypes of Progression to Macular Edema: Pooled Analysis From Independent Longitudinal Studies of up to 2 Years' Duration.

Invest Ophthalmol Vis Sci 2017 05;58(6):BIO206-BIO210

Vall d'Hebron Research Institute (VHIR) and CIBERDEM (Instituto de Salud Carlos III), Barcelona, Spain.

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http://dx.doi.org/10.1167/iovs.17-21780DOI Listing
May 2017

Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes.

Diabetologia 2017 Nov 4;60(11):2285-2298. Epub 2017 Aug 4.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00125-017-4388-yDOI Listing
November 2017

Osteoprotegerin Is a New Regulator of Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy.

Invest Ophthalmol Vis Sci 2017 06;58(7):3189-3201

Diabetes and Metabolism Research Unit and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólica Asociada (CIBERDEM), Vall d'Hebron Research Institute, Barcelona, Spain.

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http://dx.doi.org/10.1167/iovs.16-20993DOI Listing
June 2017

Calcium Dobesilate Prevents Neurodegeneration and Vascular Leakage in Experimental Diabetes.

Curr Eye Res 2017 09 2;42(9):1273-1286. Epub 2017 Jun 2.

a Diabetes and Metabolism Research Unit , Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona , Barcelona , Spain.

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http://dx.doi.org/10.1080/02713683.2017.1302591DOI Listing
September 2017

Type 2 diabetes is an independent risk factor for dementia conversion in patients with mild cognitive impairment.

J Diabetes Complications 2017 Aug 19;31(8):1272-1274. Epub 2017 Apr 19.

Institut de Recerca Vall d'Hebron, Universitat Autònoma de Barcelona (VHIR-UAB), Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10568727173031
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http://dx.doi.org/10.1016/j.jdiacomp.2017.04.018DOI Listing
August 2017

GLP-1R as a Target for the Treatment of Diabetic Retinopathy: Friend or Foe?

Diabetes 2017 06;66(6):1453-1460

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain, and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain

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http://dx.doi.org/10.2337/db16-1364DOI Listing
June 2017

Local and Systemic Inflammatory Biomarkers of Diabetic Retinopathy: An Integrative Approach.

Invest Ophthalmol Vis Sci 2017 05;58(6):BIO68-BIO75

Diabetes and Metabolism Research Unit, Institut de Recerca Hospital, Universitari Vall d'Hebron (VHIR), Barcelona, Spain 4CIBERDEM (Instituto de Salud Carlos III), Madrid, Spain.

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http://dx.doi.org/10.1167/iovs.17-21769DOI Listing
May 2017

Type 2 diabetes, risk of sleep apnea-hypopnea syndrome, and quality of life associated to sleep breathing disorders.

Endocrinol Diabetes Nutr 2017 03 13;64(3):174-176. Epub 2017 Feb 13.

CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Spain; Diabetes and Metabolism Research Unit, Institut de Recerca i Hospital Universitari Vall d'Hebron (VHIR), Universitat Autònoma de Barcelona, Pg Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S25300164173002
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http://dx.doi.org/10.1016/j.endinu.2016.10.009DOI Listing
March 2017

Sex Hormone-Binding Globulin Reduction in Metabolic Disorders May Play a Role in NAFLD Development.

Endocrinology 2017 03;158(3):545-559

Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain.

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http://dx.doi.org/10.1210/en.2016-1668DOI Listing
March 2017

Effects of depressive symptoms on clinical outcomes, inflammatory markers and quality of life after a significant weight loss in a bariatric surgery sample.

Nutr Hosp 2017 Feb 1;34(1):81-87. Epub 2017 Feb 1.

Endocrinology and Nutrition Department. Hospital Son Llàtzer. Palma de Mallorca, Spain. University Institute of Health Sciences Research (IUNICS) and Health Research Institute of Palma (IdISPa). Palma de Mallorca.

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http://dx.doi.org/10.20960/nh.979DOI Listing
February 2017

Cognitive impairment and dementia: a new emerging complication of type 2 diabetes-The diabetologist's perspective.

Acta Diabetol 2017 May 16;54(5):417-424. Epub 2017 Feb 16.

Diabetes and Metabolism Research Unit, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00592-017-0970-5DOI Listing
May 2017

Development of a Normative Database for Multifocal Electroretinography in the Context of a Multicenter Clinical Trial.

Ophthalmic Res 2017 5;57(2):107-117. Epub 2017 Jan 5.

Association for Innovation and Biomedical Research on Light and Image (AIBILI), Coimbra, Portugal.

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http://dx.doi.org/10.1159/000450958DOI Listing
February 2017

Somatostatin protects photoreceptor cells against high glucose-induced apoptosis.

Mol Vis 2016 30;22:1522-1531. Epub 2016 Dec 30.

Alberto Sols Biomedical Research Institute (IIBm) (CSIC/UAM), 28029 Madrid, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERdem), ISCIII, Madrid, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5204461PMC
January 2018

Serum 1,25-Dihydroxyvitamin D as a Biomarker of the Absence of Hypercalciuria in Postsurgical Hypoparathyroidism.

J Clin Endocrinol Metab 2017 01;102(1):259-266

Diabetes Research and Metabolism Unit, Institut de Recerca Hospital Universitari Vall d'Hebron, Barcelona, 08035 Spain; and.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2016-2987DOI Listing
January 2017

New Treatments for Type 2 Diabetes Mellitus and Cardiovascular Disease. The Revolution Has Begun.

Rev Esp Cardiol (Engl Ed) 2016 Nov 19;69(11):1005-1007. Epub 2016 Sep 19.

Grupo de Investigación en Diabetes y Metabolismo y CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), Instituto de Investigación Hospital Vall d'Hebron (VHIR), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.rec.2016.07.009DOI Listing
November 2016

Vision related quality of life in patients with type 2 diabetes in the EUROCONDOR trial.

Endocrine 2017 Jul 14;57(1):83-88. Epub 2016 Sep 14.

Laboratory of Clinical Pedagogy, Department of Medical Sciences, University of Turin, Turin, Italy.

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http://dx.doi.org/10.1007/s12020-016-1097-0DOI Listing
July 2017

Effects of the neuroprotective drugs somatostatin and brimonidine on retinal cell models of diabetic retinopathy.

Acta Diabetol 2016 Dec 23;53(6):957-964. Epub 2016 Aug 23.

Department of Medical Sciences, University of Turin, Corso AM Dogliotti 14, 10126, Turin, Italy.

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http://dx.doi.org/10.1007/s00592-016-0895-4DOI Listing
December 2016

EndoG Knockout Mice Show Increased Brown Adipocyte Recruitment in White Adipose Tissue and Improved Glucose Homeostasis.

Endocrinology 2016 Oct 22;157(10):3873-3887. Epub 2016 Aug 22.

Laboratory of Metabolism and Obesity (R.P., M.V., J.A.V.) and Group of Diabetes and Metabolism (R.S.), Vall d'Hebron-Institut de Recerca, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain; Cell Signaling and Apoptosis Group (N.B., D.S.), Biomedical Research Institute of Lleida, University of Lleida, 25003 Lleida, Spain; Department of Physiology (D.B., R.N.), Center for Research in Molecular Medicine and Chronic Diseases, Universidad de Santiago de Compostela, and Centro de Investigación Biomédica en Red on Physiopathology of Obesity and Nutrition (D.B., R.N.), 15705 Santiago de Compostela, Spain; Laboratory Animal Applied Research Platform (X.C.), Scientific Park of Barcelona, 08028 Barcelona, Spain; Centro de Investigación Biomédica en Red on Diabetes and Associated Metabolic Diseases (J.A.V. R.S.), 08003 Barcelona, Spain.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2015-1334DOI Listing
October 2016

Diabetic macular oedema.

Lancet Diabetes Endocrinol 2017 02 3;5(2):143-155. Epub 2016 Aug 3.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30052-3DOI Listing
February 2017