Rafael Rosell

Rafael Rosell

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Rafael Rosell

Rafael Rosell

Publications by authors named "Rafael Rosell"

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100Publications

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Therapeutic approaches for T790M mutation positive non-small-cell lung cancer.

Expert Rev Anticancer Ther 2018 Oct 14;18(10):1021-1030. Epub 2018 Aug 14.

c Coyote Research Group, Pangaea Oncology, Laboratory of Molecular Biology , Quirón-Dexeus University Institute , Barcelona , Spain.

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October 2018

Anti-Epidermal Growth Factor Vaccine Antibodies Enhance the Efficacy of Tyrosine Kinase Inhibitors and Delay the Emergence of Resistance in EGFR Mutant Lung Cancer Cells.

J Thorac Oncol 2018 Sep 8;13(9):1324-1337. Epub 2018 May 8.

Instituto Oncológico Dr. Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain; Catalan Institute of Oncology and Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Spain.

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September 2018

Circulating tumour DNA genomics in EGFR-mutant lung adenocarcinoma.

Lancet Respir Med 2018 Sep 17;6(9):649-651. Epub 2018 Jul 17.

Germans Trias i Pujol Research Institute, Barcelona, Spain; Institute of Oncology, University Hospital Sagrat Cor, QuironSalud Group, Barcelona, Spain.

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September 2018

Improvement in Overall Survival in a Randomized Study That Compared Dacomitinib With Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer and EGFR-Activating Mutations.

J Clin Oncol 2018 Aug 4;36(22):2244-2250. Epub 2018 Jun 4.

Tony S. Mok, State Key Laboratory of South China, Chinese University of Hong Kong, Hong Kong; Ying Cheng, Jilin Provincial Cancer Hospital, Changchun; Xiangdong Zhou, First Affiliated Hospital of Third Military Medical University, Chongqing; Yi-Long Wu, Guangdong Lung Cancer Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China; Ki Hyeong Lee, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea; Kazuhiko Nakagawa, Kindai University Hospital, Osaka; Seiji Niho, National Cancer Center Hospital East, Kashiwa, Japan; Min Lee, SFJ Asia Pacific, Singapore; Rolf Linke, SFJ Pharmaceuticals Group, Pleasanton, CA; Rafael Rosell, Catalan Institute of Oncology, Barcelona; Jesus Corral, Hospital Universitario Virgen del Rocio, Seville, Spain; Maria Rita Migliorino, Pulmonary Oncology Unit, San Camillo-Forlanini Hospital, Rome, Italy; Adam Pluzanski, The Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland; Eric I. Sbar, Pfizer, Collegeville, PA; Tao Wang and Jane Liang White, Pfizer, Groton, CT.

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August 2018

Activation of viral defense signaling in cancer.

Ther Adv Med Oncol 2018 29;10:1758835918793105. Epub 2018 Aug 29.

Rosell Oncology Institute (IOR), Dexeus University Hospital, Quironsalud Group, Barcelona, Spain Rosell Oncology Institute (IOR), Sagrat Cor University Hospital, Quironsalud Group, Barcelona, Spain Catalan Institute of Oncology, Germans Trias I Pujol University Hospital, Badalona, Spain.

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August 2018

Gene Expression Signatures Predicting Survival and Chemotherapy Benefit in Patients with Resected Non-small-Cell Lung Cancer.

EBioMedicine 2018 Jul;33:16-17

Medical Oncology Department, University Hospital Sagrat Cor, QuironSalud Group, Institute of Oncology Rosell, Barcelona, Spain.

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July 2018

Combining plasma-based biosources to predict treatment response in NSCLC patients.

Ann Oncol 2018 Jul 13. Epub 2018 Jul 13.

Pangaea Oncology, Laboratory of Molecular Biology, Coyote Reserach Group, Quirón-Dexeus University Institute, Barcelona, Spain.

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July 2018

The Present and Future of Liquid Biopsies in Non-Small Cell Lung Cancer: Combining Four Biosources for Diagnosis, Prognosis, Prediction, and Disease Monitoring.

Curr Oncol Rep 2018 Jul 20;20(9):70. Epub 2018 Jul 20.

Pangaea Oncology, Laboratory of Molecular Biology, Quirón-Dexeus University Institute, Sabino Arana 5-19, 08028, Barcelona, Spain.

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July 2018

Spotlight on ceritinib in the treatment of ALK+ NSCLC: design, development and place in therapy.

Drug Des Devel Ther 2017 5;11:2047-2063. Epub 2017 Jul 5.

Medical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, Messina, Italy.

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June 2018

The Value of Early Depth of Response in Predicting Long-Term Outcome in EGFR-Mutant Lung Cancer.

J Thorac Oncol 2018 Jun 23;13(6):792-800. Epub 2018 Mar 23.

Graduate Institute of Oncology, National Taiwan University and Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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June 2018

How to optimize the treatment strategy for patients with EGFR-mutant stage IA lung adenocarcinoma: an international multidisciplinary team.

J Thorac Dis 2018 Jun;10(6):3883-3890

Department of Medical Oncology, Shanghai Pulmonary Hospital, Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai 200433, China.

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June 2018

RNA Analysis as a Tool to Determine Clinically Relevant Gene Fusions and Splice Variants.

Arch Pathol Lab Med 2018 Apr;142(4):474-479

From the Department of Pathology, Hospital Clínic, Barcelona, Spain (Dr Teixidó); Translational Genomics and Targeted Therapeutics in Solid Tumors, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (Dr Teixidó); Pangaea Oncology, Oncology Laboratory, Dexeus University Hospital - Quirónsalud Group, Barcelona, Spain (Ms Giménez-Capitán and Drs Molina-Vila, Peg, Karachaliou, Castellví, and Rosell); the Department of Pathology, Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain (Drs Peg and Castellví); Morphological Sciences Department, Universitat Autònoma de Barcelona, Barcelona, Spain (Drs Peg and Castellví); Institute of Oncology Rosell (IOR), University Hospital Sagrat Cor and Quirónsalud Group, Barcelona, Spain (Drs Karachaliou and Rosell); the Department of Medical Oncology, Canarias University Hospital, San Cristóbal de La Laguna, Tenerife, Spain (Dr Rodríguez-Capote); and Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain (Dr Rosell).

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April 2018

STAT3 as a potential immunotherapy biomarker in oncogene-addicted non-small cell lung cancer.

Ther Adv Med Oncol 2018 2;10:1758835918763744. Epub 2018 Apr 2.

Coyote Research Group, Pangaea Oncology, Laboratory of Molecular Biology, Quirón-Dexeus University Institute, Barcelona, Spain.

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April 2018

Coordinated strategies for early detection of lung cancer.

Authors:
Rafael Rosell

J Thorac Dis 2018 Apr;10(Suppl 7):S776

Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Barcelona, Spain.

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April 2018

Liquid biopsy for lung cancer early detection.

J Thorac Dis 2018 Apr;10(Suppl 7):S882-S897

Cancer Biology and Precision Medicine Program, Germans Trias i Pujol University Hospital, Badalona, Spain.

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April 2018

Osimertinib in untreated epidermal growth factor receptor ()-mutated advanced non-small cell lung cancer.

Transl Lung Cancer Res 2018 Apr;7(Suppl 2):S165-S170

Medical Oncology Unit, Department of Human Pathology of Adult and Evolutive Age "G. Barresi", University of Messina, Messina, Italy.

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April 2018

Common Co-activation of AXL and CDCP1 in EGFR-mutation-positive Non-smallcell Lung Cancer Associated With Poor Prognosis.

EBioMedicine 2018 Mar 5;29:112-127. Epub 2018 Feb 5.

Pangaea Oncology, Laboratory of Molecular Biology, Coyote Reserach Group, Quirón-Dexeus University Institute, Barcelona, Spain; Institut d'Investigació en Ciències Germans Trias i Pujol, Badalona, Spain; Instituto Oncológico Dr Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain; Institut Català d'Oncologia, Hospital Germans Trias i Pujol, Badalona, Spain. Electronic address:

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March 2018

Adjuvant therapy for resected EGFR-mutant non-small-cell lung cancer.

Lancet Oncol 2018 Mar;19(3):e126

University Hospital Sagrat Cor, Quirónsalud Group, Barcelona, Spain.

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March 2018

Science and biology drives the immune system to cure lung cancer patients: a revolution but not without challenges.

Ther Adv Med Oncol 2018 22;10:1758835918763723. Epub 2018 Mar 22.

Instituto Oncológico Dr Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain; Institut d'Investigació en Ciències Germans Trias i Pujol, Badalona, Spain; Institut Català d'Oncologia, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.

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March 2018

Clinical assessment of immune-related adverse events.

Ther Adv Med Oncol 2018 30;10:1758835918764628. Epub 2018 Mar 30.

Department of Medical Oncology, Dr Rosell Oncology Institute, Barcelona, Spain.

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March 2018

Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.

Cancer Treat Res Commun 2018 1;15:21-31. Epub 2018 Mar 1.

Genomes For life-GCAT Lab. Program of Predictive and Personalized Medicine of Cancer (PMPPC), Institute for Health Science Research Germans Trias i Pujol (IGTP), Can Ruti Biomedical Campus, Crta de Can Ruti, Camí de les Escoles S/N, 08916 Badalona, Barcelona, Spain. Electronic address:

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March 2018

An innovative mesothelioma treatment based on miR-16 mimic loaded EGFR targeted minicells (TargomiRs).

Transl Lung Cancer Res 2018 Feb;7(Suppl 1):S1-S4

Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain.

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February 2018

Combination of immunotherapy with targeted therapies in advanced non-small cell lung cancer (NSCLC).

Ther Adv Med Oncol 2018 9;10:1758834017745012. Epub 2018 Jan 9.

Instituto Oncológico Dr Rosell (IOR), University Hospital General de Catalunya, Sant Cugat del Vallès, Spain.

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January 2018

Interferon gamma, an important marker of response to immune checkpoint blockade in non-small cell lung cancer and melanoma patients.

Ther Adv Med Oncol 2018 18;10:1758834017749748. Epub 2018 Jan 18.

Institut Català d'Oncologia, Hospital Universitari Germans Trias i Pujol, Badalona, Spain Institut d'Investigació en Ciències Germans Trias i Pujol, Badalona, Spain Instituto Oncológico Dr Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain.

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January 2018

IDH mutation status trumps the Pignatti risk score as a prognostic marker in low-grade gliomas.

J Neurooncol 2017 Nov 7;135(2):273-284. Epub 2017 Sep 7.

Medical Oncology Service, Catalan Institute of Oncology (ICO), Hospital Germans Trias i Pujol, Ctra Canyet s/n, 08916, Badalona, Barcelona, Spain.

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November 2017

BRAF and BRAF-inactivating mutations in NSCLC.

Lancet Oncol 2017 10 11;18(10):1286-1287. Epub 2017 Sep 11.

Dr Rosell Oncology Institute, University Hospital Sagrat Cor, Barcelona, Spain.

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October 2017

Homage to the titans of Chinese investigation and the race for lung cancer curability.

Authors:
Rafael Rosell

J Thorac Dis 2017 Oct;9(Suppl 11):S1150

Director, Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital; Associate Professor of Medicine, Autonomous University of Barcelona (UAB), Campus Can Ruti, Badalona 08916, Barcelona, Spain. (Email:

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October 2017

Possible application of circulating free tumor DNA in non-small cell lung cancer patients.

J Thorac Dis 2017 Oct;9(Suppl 13):S1364-S1372

Instituto Oncológico Dr Rosell (IOR), University Hospital Sagrat Cor, Barcelona, Spain.

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October 2017

Brain metastases in patients with EGFR-mutant non-small-cell lung cancer.

Lancet Respir Med 2017 09 19;5(9):669-671. Epub 2017 Jul 19.

Instituto Oncológico Dr Rosell, University Hospital Sagrat Cor, Barcelona, Spain.

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September 2017

Alectinib versus Crizotinib in Untreated ALK-Positive Non-Small-Cell Lung Cancer.

N Engl J Med 2017 08 6;377(9):829-838. Epub 2017 Jun 6.

From Lausanne University Hospital, Lausanne (S.P.), and F. Hoffmann-La Roche, Basel (A.Z., E.M., S. Golding, B.B., J.N.) - both in Switzerland; University of Colorado, Denver (D.R.C.); Massachusetts General Hospital, Boston (A.T.S.); University of Michigan, Ann Arbor (S. Gadgeel); Samsung Medical Center, Sungkyunkwan University School of Medicine (J.S.A.), and Seoul National University Hospital (D.-W.K.) - both in Seoul, South Korea; Chao Family Comprehensive Cancer Center, University of California, Irvine, School of Medicine, Orange (S.-H.I.O.); Department of Medical Oncology, Léon Bérard Cancer Center, Lyon, France (M.P.); Department of Oncology and Radiotherapy, Medical University of Gdansk, Gdansk, Poland (R.D.); Catalan Institute of Oncology, Barcelona (R.R.); Roche Innovation Center, New York (P.N.M.); and State Key Laboratory of South China, Chinese University of Hong Kong, Hong Kong (T.M.).

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August 2017

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.

Cancer Cell 2017 08;32(2):238-252.e9

Department of Neurosurgery, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Brain Tumor Center Amsterdam, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, 149 13(th) Street, Charlestown, MA 02129, USA. Electronic address:

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August 2017

Osimertinib in the treatment of non-small-cell lung cancer: design, development and place in therapy.

Lung Cancer (Auckl) 2017 18;8:109-125. Epub 2017 Aug 18.

Department of Oncology, Institute of Oncology Rosell (IOR), Quirón-Dexeus University Institute, Barcelona.

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August 2017

YB-1 regulates tumor growth by promoting MACC1/c-Met pathway in human lung adenocarcinoma.

Oncotarget 2017 Jul;8(29):48110-48125

Department of Thoracic Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.

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July 2017

Second-line therapy of squamous non-small cell lung cancer: an evolving landscape.

Expert Rev Respir Med 2017 06 15;11(6):469-479. Epub 2017 May 15.

e Medical Oncology Unit, Department of Human Pathology "G. Barresi" , University of Messina , Messina , Italy.

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June 2017

A phase Ib trial of continuous once-daily oral afatinib plus sirolimus in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer and/or disease progression following prior erlotinib or gefitinib.

Lung Cancer 2017 06 22;108:154-160. Epub 2017 Mar 22.

Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain; Dr. Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain; Molecular Oncology Research Foundation (MORe), Barcelona, Spain; Universitat Autònoma de Barcelona (UAB) Campus Can Ruti, Carretera de Canyet s/n, 08916 Badalona, Barcelona, Spain. Electronic address:

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June 2017

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

J Clin Oncol 2017 May 13;35(13):1403-1410. Epub 2017 Mar 13.

Oliver Gautschi, Kristin Zeidler, and Joachim Diebold, Lucerne Cantonal Hospital, Luzern; Patrizia Froesch, Ente Ospedaliero Cantonale, Bellinzona; Martin Früh, Kantonsspital St Gallen, St Gallen; Sacha I. Rothschild, University Hospital Basel, Basel, Switzerland; Julie Milia and Julien Mazières, Hôpital Larrey; Thomas Filleron, Institut Universitaire du Cancer, Claudius Regaud, Toulouse; Benjamin Besse and Jordi Remon-Masip, Institute Gustave Roussy, Villejuif; Gérard Zalcman, University Hospital Bichat, Paris; Isabelle Monnet, Centre Hospitalier Intercommunal de Creteil, Creteil; Florian Cabillic, Université de Rennes 1, Rennes, France; Juergen Wolf and Sebastian Michels, Center for Integrated Oncology, Cologne; Georg Pall, Fachkliniken Wangen, Wangen Im Allgäu; Arne Warth, Heidelberg University Hospital; Thomas Muley, Thoraxklinik at University of Heidelberg and Translational Lung Research Center, Heidelberg, Germany; David P. Carbone and Dwight Owen, Ohio State University Comprehensive Cancer Center, Columbus; Vamsidhar Velcheti, Cleveland Clinic, Pepper Pike, OH; Ross Camidge and Vignhesh Narayanan, University of Colorado, Denver; Robert C. Doebele, University of Colorado, Aurora, CO; Pasi A. Janne and Mark M. Awad, Dana-Farber Cancer Institute, Boston, MA; Daniel D. Karp, The University of Texas MD Anderson Cancer Center, Houston, TX; Heather A. Wakelee and Joel W. Neal, Stanford University, Stanford; Sai-Hong Ignatius Ou, University of California, Irvine, Orange; David R. Gandara and Jonathan W. Riess, University of California, Davis Cancer Center, Sacramento, CA; Alexander Drilon, Memorial Sloan Kettering Cancer Center, New York, NY; Nir Peled, Davidoff Cancer Center, Petach Tiqwa, Israël; Chul-Cho Byoung, Yonseï Cancer Center, Seoul, Republic of Korea; Michael Van Den Heuvel, Netherlands Cancer Institute, Amsterdam, the Netherlands; Tony S.K. Mok, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China; James C.H. Yang and Jin-Yuan Shih, National Taiwan University Hospital, Taipei, Republic of China; Sanjay Popat, Royal Marsden Hospital, London, United Kingdom; and Rafael Rosell and Niki Karachaliou, Catalan Institute of Oncology, Barcelona, Spain.

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May 2017

Neutrophils dominate the immune landscape of non-small cell lung cancer.

J Thorac Dis 2017 May;9(5):E468-E469

Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain.

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May 2017

Beyond platinum treatment for NSCLC: what does the future hold?

Expert Rev Anticancer Ther 2017 04 8;17(4):293-295. Epub 2017 Feb 8.

c Institute of Oncology Rosell (IOR), Quirón-Dexeus University Institute , Barcelona , Spain.

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April 2017

Low RAP80 mRNA expression correlates with shorter survival in sporadic high-grade serous ovarian carcinoma.

Int J Biol Markers 2017 Mar 2;32(1):e90-e95. Epub 2017 Mar 2.

 Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona - Spain.

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March 2017

Correlation of DNA Repair Gene Polymorphisms With Clinical Outcome in Patients With Locally Advanced Non-Small-Cell Lung Cancer Receiving Induction Chemotherapy Followed by Surgery.

Clin Lung Cancer 2017 03 9;18(2):178-188.e4. Epub 2016 Nov 9.

Cancer Biology and Precision Medicine Program, Hospital Germans Trias i Pujol, Catalan Institute of Oncology, Badalona, Spain; Dr Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain; Germans Trias i Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Badalona, Spain.

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March 2017

High BIM mRNA levels are associated with longer survival in advanced gastric cancer.

Oncol Lett 2017 Mar 1;13(3):1826-1834. Epub 2017 Feb 1.

The Comprehensive Cancer Centre of Drum Tower Hospital, Department of Oncology, The Affiliated Drum Tower Hospital of Nanjing University, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu 210008, P.R. China.

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March 2017

HER3 as a Therapeutic Target in Cancer.

BioDrugs 2017 Feb;31(1):63-73

Germans Trias i Pujol Research Institute, Badalona, Spain.

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February 2017

Pharmacological management of relapsed/refractory NSCLC with chemical drugs.

Expert Opin Pharmacother 2017 Feb 29;18(3):295-304. Epub 2017 Jan 29.

e Cancer Biology & Precision Medicine Program , Institut d'Investigació en Ciències Germans Trias i Pujol , Badalona , Spain.

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February 2017

Feasibility of cell-free circulating tumor DNA testing for lung cancer.

Biomark Med 2016 14;10(4):417-30. Epub 2016 Mar 14.

Dr Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain.

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December 2016

RET inhibitors for patients with RET fusion-positive and RET wild-type non-small-cell lung cancer.

Lancet Oncol 2016 12 4;17(12):1623-1625. Epub 2016 Nov 4.

Germans Trias i Pujol Health Sciences Research Institute, Badalona, Spain; University Hospital Sagrat Cor, Barcelona, Spain.

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December 2016

Liquid Biopsy in Non-Small Cell Lung Cancer.

Front Med (Lausanne) 2016 23;3:69. Epub 2016 Dec 23.

Instituto Oncológico Dr Rosell, Quirón Dexeus University Hospital, Barcelona, Spain; Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain.

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December 2016

Human endogenous retroviruses and cancer.

Cancer Biol Med 2016 Dec;13(4):483-488

Translational Cancer Research Unit, Instituto Oncológico Dr Rosell, Quirón Dexeus University Hospital, Barcelona 08028, Spain; Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias I Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Badalona, 08916, Spain; Fundación Molecular Oncology Research, Barcelona 08028, Spain.

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December 2016

Implications of Blood-Based T790M Genotyping and Beyond in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer.

J Clin Oncol 2016 10 18;34(28):3361-2. Epub 2016 Jul 18.

Germans Trias i Pujol Health Sciences Research Institute, Badalona; and University Hospital Sagrat Cor, Barcelona, Spain.

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October 2016

Personalized treatment in advanced ALK-positive non-small cell lung cancer: from bench to clinical practice.

Onco Targets Ther 2016 17;9:6361-6376. Epub 2016 Oct 17.

Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy.

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October 2016

mutations in the circulating free DNA (cfDNA) of non-small cell lung cancer (NSCLC) patients.

Transl Lung Cancer Res 2016 Oct;5(5):511-516

Pangaea Biotech, Laboratory of Oncology, Quirón Dexeus University Hospital, 08028 Barcelona, Spain;; Dr Rosell Oncology Institute, Quirón Dexeus University Hospital, 08028 Barcelona, Spain;; Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Crta de Canyet s/n, 08016 Badalona, Spain;; Autonomous University of Barcelona (UAB), Campus Can Ruti, Crta de Canyet s/n, 08016 Badalona, Spain;; Molecular Oncology Research (MORe) Foundation, 08028 Barcelona, Spain.

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October 2016

Fusion gene and splice variant analyses in liquid biopsies of lung cancer patients.

Transl Lung Cancer Res 2016 Oct;5(5):525-531

Pangaea Biotech, Laboratory of Oncology, Quirón Dexeus University Hospital, Barcelona, Spain;; Dr Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain;; Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain;; Autonomous University of Barcelona (UAB), Campus Can Ruti, Badalona, Spain;; Molecular Oncology Research (MORe) Foundation, Barcelona, Spain.

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October 2016

Usefulness of circulating free DNA for monitoring epidermal growth factor receptor mutations in advanced non-small cell lung cancer patients: a case report.

Transl Lung Cancer Res 2016 Oct;5(5):532-537

Pangaea Biotech, Medical Oncology Laboratory, Dexeus University Hospital, Quirónsalud Group, Barcelona, Spain;; Translational Cancer Research Unit, Instituto Oncológico Dr Rosell, Dexeus University Hospital-Quirónsalud Group, Barcelona, Spain;; Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Germans Triasi Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Badalona, Barcelona, Spain.

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October 2016

Annual or biennial lung cancer CT screening?

J Thorac Dis 2016 Sep;8(9):2424-2426

Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain;; Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain.

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September 2016

Unraveling the genomic complexity of small cell lung cancer.

Transl Lung Cancer Res 2016 Aug;5(4):363-6

Autonomous University of Barcelona, Germans Trias i Pujol Health Sciences Research Institute, Badalona, Spain;; Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain.

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August 2016

Recent developments in the use of immunotherapy in non-small cell lung cancer.

Expert Rev Respir Med 2016 07 13;10(7):781-98. Epub 2016 May 13.

e Dr Rosell Oncology Institute , Quirón Dexeus University Hospital , Barcelona , Spain.

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July 2016

Lung cancer: Using ctDNA to track EGFR and KRAS mutations in advanced-stage disease.

Nat Rev Clin Oncol 2016 07 1;13(7):401-2. Epub 2016 Jun 1.

Germans Trias i Pujol Health Sciences Institute, Campus Can Ruti, Carretera de Can Ruti, Cami de les Escoles S/N, Badalona, Barcelona 08916, Spain.

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July 2016

Trends in immunotherapy for brain metastases.

Lancet Oncol 2016 07 3;17(7):859-860. Epub 2016 Jun 3.

Germans Trias i Pujol Health Sciences Research Institute, Badalona, Spain; University Hospital Sagrat Cor, Barcelona, Spain.

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July 2016

Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non-Small-Cell Lung Cancer.

J Clin Oncol 2016 Apr 1;34(11):1223-30. Epub 2016 Feb 1.

Elisabeth Brambilla and Sylvie Lantuejoul, Institut Albert Bonniot-Institut National de la Santé et de la Recherche Médicale U823; and Centre Hospitalier Universitaire Albert Michallon, Grenoble; Gwénaël Le Teuff, Sophie Marguet, Ariane Dunant, Thierry Le Chevalier, and Jean-Charles Soria, Institut Gustave Roussy, Villejuif; Gwénaël Le Teuff, Sophie Marguet, Ariane Dunant, Thierry Le Chevalier, and Jean-Charles Soria, Université Paris-Sud, Orsay; Gwénaël Le Teuff, Université Paris-Saclay, Saint-Aubin; Jean-Yves Douillard, Centre René Gauducheau Institut de Cancerologie de l'Ouest, Saint-Herblain, France; Stephen Graziano, State University of New York Upstate Medical University, Syracuse, NY; Robert Pirker and Martin Filipits, Medical University of Vienna, Vienna; Helmut Popper, Medical University of Graz, Graz, Austria; Rafael Rosell, Catalan Institute of Oncology, Barcelona, Spain; Robert Kratzke, University of Minnesota, Minneapolis, MN; Frances A. Shepherd and Ming Sound Tsao, Princess Margaret Cancer Centre; Frances A. Shepherd and Ming Sound Tsao, University of Toronto, Toronto; and Lesley Seymour, Queen's University, Kingston, Ontario, Canada.

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April 2016

Cellular and molecular biology of small cell lung cancer: an overview.

Transl Lung Cancer Res 2016 Feb;5(1):2-15

1 Instituto Oncolόgico Dr Rosell, Quirón Dexeus University Hospital, Barcelona, Spain ; 2 Department of Medical Oncology, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy ; 3 Division of Thoracic Oncology, European Institute of Oncology (IEO), Milan, Italy ; 4 Pangaea Biotech, Barcelona, Spain ; 5 Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain ; 6 Molecular Oncology Research (MORe) Foundation, Barcelona, Spain ; 7 Germans Trias i Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Badalona, Barcelona, Spain.

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February 2016

Cancer stem cells in small cell lung cancer.

Transl Lung Cancer Res 2016 Feb;5(1):16-25

1 Pangaea Biotech S.L, Quirón Dexeus University Hospital, Barcelona, Spain ; 2 Santa Maria delle Croci City Hospital, Ravenna, Italy ; 3 Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Spain ; 4 Instituto Oncológico Dr Rosell, Quirón Dexeus University Hospital, Barcelona, Spain ; 5 Fundación Molecular Oncology Research, Barcelona, Spain.

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February 2016

Targeted drugs in small-cell lung cancer.

Transl Lung Cancer Res 2016 Feb;5(1):51-70

1 Medical Oncology Unit, Department of Human Pathology "G. Barresi", University of Messina, Messina, Italy ; 2 Dr Rosell Oncology Institute, Quirón Dexeus University Hospital, Barcelona, Spain ; 3 Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy ; 4 Pangaea Biotech, Barcelona, Spain ; 5 Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain ; 6 Germans Trias i Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Badalona, Barcelona, Spain ; 7 Molecular Oncology Research (MORe) Foundation, Barcelona, Spain.

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February 2016

Immunotherapy meets targeted therapy: will this team end the war against cancer?

Transl Lung Cancer Res 2015 Dec;4(6):752-5

1 Rosell Oncology Institute, Quirón-Dexeus University Hospital, Barcelona, Spain ; 2 Pangaea Biotech, Barcelona, Spain ; 3 Institut Quimic de Sarriá, Barcelona, Spain ; 4 Institut Catalá d'Oncologia, Badalona, Spain.

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December 2015

Results of clinical trials with anti-programmed death 1/programmed death ligand 1 inhibitors in lung cancer.

Transl Lung Cancer Res 2015 Dec;4(6):756-62

1 Instituto Oncológico Dr Rosell, Quirón-Dexeus University Hospital, Barcelona, Spain ; 2 Instituto Nacional de Cancerología, México City, México.

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December 2015