Rafael A Larocca

Rafael A Larocca

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Rafael A Larocca

Rafael A Larocca

Publications by authors named "Rafael A Larocca"

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26Publications

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Alpha-defensin 5 differentially modulates adenovirus vaccine vectors from different serotypes in vivo.

PLoS Pathog 2019 12 16;15(12):e1008180. Epub 2019 Dec 16.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1008180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936886PMC
December 2019

Adenovirus Vector-Based Vaccines Confer Maternal-Fetal Protection against Zika Virus Challenge in Pregnant IFN-αβR Mice.

Cell Host Microbe 2019 11 24;26(5):591-600.e4. Epub 2019 Oct 24.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863051PMC
November 2019

Assessment of Immunogenicity and Efficacy of a Zika Vaccine Using Modified Vaccinia Ankara Virus as Carriers.

Pathogens 2019 Nov 2;8(4). Epub 2019 Nov 2.

The Jenner Institute, Nuffield Department of Medicine, University of Oxford, The Henry Wellcome Building for Molecular Physiology, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.3390/pathogens8040216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963679PMC
November 2019

Immunogenicity and Cross-Reactivity of Rhesus Adenoviral Vectors.

J Virol 2018 06 14;92(11). Epub 2018 May 14.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/JVI.00159-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952169PMC
June 2018

Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys.

Nat Med 2018 06 4;24(6):721-723. Epub 2018 Jun 4.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41591-018-0056-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992501PMC
June 2018

Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys.

Cell 2018 05 29;173(5):1111-1122.e10. Epub 2018 Mar 29.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959775PMC
May 2018

Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4 T cell responses that impair CD8 T cell function.

Sci Immunol 2016 Nov 4;1(5). Epub 2016 Nov 4.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1126/sciimmunol.aaf7643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322800PMC
November 2016

Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells.

J Immunol 2016 09 22;197(5):1809-22. Epub 2016 Jul 22.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215; Ragon Institute of MGH, MIT, and Harvard, Boston, MA 02139

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http://dx.doi.org/10.4049/jimmunol.1600591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991249PMC
September 2016

Transient CD4+ T Cell Depletion Results in Delayed Development of Functional Vaccine-Elicited Antibody Responses.

J Virol 2016 May 14;90(9):4278-4288. Epub 2016 Apr 14.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/JVI.00039-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836333PMC
May 2016

Hexon hypervariable region-modified adenovirus type 5 (Ad5) vectors display reduced hepatotoxicity but induce T lymphocyte phenotypes similar to Ad5 vectors.

Clin Vaccine Immunol 2014 Aug 18;21(8):1137-44. Epub 2014 Jun 18.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA Ragon Institute of MGH, MIT, and Harvard, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/CVI.00207-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135912PMC
August 2014

Longitudinal requirement for CD4+ T cell help for adenovirus vector-elicited CD8+ T cell responses.

J Immunol 2014 Jun 28;192(11):5214-25. Epub 2014 Apr 28.

Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA 02215; and Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139

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http://dx.doi.org/10.4049/jimmunol.1302806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025612PMC
June 2014

Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells.

Eur J Immunol 2014 Mar 13;44(3):794-806. Epub 2014 Jan 13.

Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil; Department of Medicine, Harvard Medical School, Beth Israel Medical Deaconess Center, Transplant Institute, Boston, MA, USA.

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http://doi.wiley.com/10.1002/eji.201343592
Publisher Site
http://dx.doi.org/10.1002/eji.201343592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973395PMC
March 2014