Publications by authors named "Radovan Dvorsky"

39Publications

Structural snapshots of RAF kinase interactions.

Biochem Soc Trans 2018 12 31;46(6):1393-1406. Epub 2018 Oct 31.

Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany

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http://biochemsoctrans.org/lookup/doi/10.1042/BST20170528
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http://dx.doi.org/10.1042/BST20170528DOI Listing
December 2018

Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoforms.

Crit Rev Biochem Mol Biol 2018 04 19;53(2):130-156. Epub 2018 Feb 19.

a Institute of Biochemistry and Molecular Biology II, Medical Faculty , Heinrich-Heine University , Düsseldorf , Germany.

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https://www.tandfonline.com/doi/full/10.1080/10409238.2018.1
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http://dx.doi.org/10.1080/10409238.2018.1431605DOI Listing
April 2018

The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions.

PLoS One 2016 9;11(12):e0167145. Epub 2016 Dec 9.

Institute of Biochemistry and Molecular Biology II, Medical Faculty of the Heinrich-Heine University, Düsseldorf, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167145PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147862PMC
July 2017

IQGAP1 Interaction with RHO Family Proteins Revisited: KINETIC AND EQUILIBRIUM EVIDENCE FOR MULTIPLE DISTINCT BINDING SITES.

J Biol Chem 2016 Dec 4;291(51):26364-26376. Epub 2016 Nov 4.

From the Institute of Biochemistry and Molecular Biology II, Medical Faculty of the Heinrich-Heine University, 40225 Düsseldorf, Germany,

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http://dx.doi.org/10.1074/jbc.M116.752121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159498PMC
December 2016

Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.

J Biol Chem 2016 09 1;291(39):20353-71. Epub 2016 Aug 1.

From the Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225 Düsseldorf, Germany,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034035PMC
http://dx.doi.org/10.1074/jbc.M116.736967DOI Listing
September 2016

Interaction characteristics of Plexin-B1 with Rho family proteins.

Biochem Biophys Res Commun 2013 May 17;434(4):785-90. Epub 2013 Apr 17.

Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine-Universität, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2013.04.012DOI Listing
May 2013

Deciphering the molecular and functional basis of Dbl family proteins: a novel systematic approach toward classification of selective activation of the Rho family proteins.

J Biol Chem 2013 Feb 19;288(6):4486-500. Epub 2012 Dec 19.

Institut für Biochemie and Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine-Universität, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1074/jbc.M112.429746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567697PMC
February 2013

New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm.

Biol Chem 2013 Jan;394(1):89-95

Institut für Biochemie und Molekularbiologie II, Medizinische Fakultät der Heinrich-Heine-Universität, D-40225 Düsseldorf, Deutschland.

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https://www.degruyter.com/view/j/bchm.2013.394.issue-1/hsz-2
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http://dx.doi.org/10.1515/hsz-2012-0207DOI Listing
January 2013

Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes.

Hum Mol Genet 2013 Jan 11;22(2):262-70. Epub 2012 Oct 11.

Institute of Biochemistry & Molecular Biology II, Heinrich-Heine University, Düsseldorf 40225, Germany.

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http://dx.doi.org/10.1093/hmg/dds426DOI Listing
January 2013

Monoclonal antibody MN423 as a stable mold facilitates structure determination of disordered tau protein.

J Struct Biol 2010 Jul 23;171(1):74-81. Epub 2010 Feb 23.

Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska cesta 9, 845 10 Bratislava, Slovakia.

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http://linkinghub.elsevier.com/retrieve/pii/S104784771000063
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http://dx.doi.org/10.1016/j.jsb.2010.02.016DOI Listing
July 2010

Structure of RNase Sa2 complexes with mononucleotides--new aspects of catalytic reaction and substrate recognition.

FEBS J 2009 Aug 25;276(15):4156-68. Epub 2009 Jun 25.

Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovakia.

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http://dx.doi.org/10.1111/j.1742-4658.2009.07125.xDOI Listing
August 2009

A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family.

Biochem J 2009 Jan;417(1):371-7

Institute of Biochemistry and Molecular Biology II, Heinrich Heine University Medical Center, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1042/BJ20081535DOI Listing
January 2009

Mapping the isoprenoid binding pocket of PDEdelta by a semisynthetic, photoactivatable N-Ras lipoprotein.

Chembiochem 2009 Jan;10(1):98-108

Department of Structural Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn Strasse 11, Dortmund, Germany.

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http://dx.doi.org/10.1002/cbic.200800275DOI Listing
January 2009

X-ray structure of the PHF core C-terminus: insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease.

FEBS Lett 2007 Dec 3;581(30):5872-8. Epub 2007 Dec 3.

Institute of Neuroimmunology, Slovak Academy of Sciences, Dubravska cesta 9, 845 10 Bratislava, Slovakia.

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http://dx.doi.org/10.1016/j.febslet.2007.11.067DOI Listing
December 2007

A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome.

J Biol Chem 2007 Apr 12;282(17):13011-21. Epub 2007 Feb 12.

Max Planck Institute of Molecular Physiology, Department of Structural Biology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M608872200
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http://dx.doi.org/10.1074/jbc.M608872200DOI Listing
April 2007

Purification and biochemical properties of Rac1, 2, 3 and the splice variant Rac1b.

Methods Enzymol 2006 ;406:1-11

Max-Planck Institute for Molecular Physiology, Department of Structural Biology, Dortmund, Germany.

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http://dx.doi.org/10.1016/S0076-6879(06)06001-0DOI Listing
March 2006

Monitoring the real-time kinetics of the hydrolysis reaction of guanine nucleotide-binding proteins.

Biol Chem 2005 Nov;386(11):1105-14

Department of Structural Biology, Max-Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, D-44227 Dortmund, Germany.

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http://dx.doi.org/10.1515/BC.2005.127DOI Listing
November 2005

An electrostatic steering mechanism of Cdc42 recognition by Wiskott-Aldrich syndrome proteins.

Mol Cell 2005 Oct;20(2):313-24

Abteilung Strukturelle Biologie, Max-Planck-Institut für Molekulare Physiologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650501602
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http://dx.doi.org/10.1016/j.molcel.2005.08.036DOI Listing
October 2005

Always look on the bright site of Rho: structural implications for a conserved intermolecular interface.

EMBO Rep 2004 Dec;5(12):1130-6

Department of Structural Biology, Max Planck Institute for Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://dx.doi.org/10.1038/sj.embor.7400293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1299188PMC
December 2004

Comparative functional analysis of the Rac GTPases.

FEBS Lett 2003 Dec;555(3):556-60

Max-Planck-Institute of Molecular Physiology, Department of Structural Biology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.

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http://dx.doi.org/10.1016/s0014-5793(03)01351-6DOI Listing
December 2003

Structural insights into the interaction of ROCKI with the switch regions of RhoA.

J Biol Chem 2004 Feb 2;279(8):7098-104. Epub 2003 Dec 2.

Max-Planck-Institute fuer Molekulare Physiologie, Abteilung Strukturelle Biologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M311911200
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http://dx.doi.org/10.1074/jbc.M311911200DOI Listing
February 2004

Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase.

J Biol Chem 2004 Feb 18;279(6):4743-9. Epub 2003 Nov 18.

Max-Planck-Institut für molekulare Physiologie, Abteilung Strukturelle Biologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

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http://dx.doi.org/10.1074/jbc.M310281200DOI Listing
February 2004

Molecular cloning and 3D structure prediction of the first raw-starch-degrading glucoamylase without a separate starch-binding domain.

Arch Biochem Biophys 2003 Mar;411(2):189-95

Department of Biochemistry, Institute of Molecular Biology, Slovak Academy of Sciences, Dúbravská cesta 21, 842 51 Bratislava, Slovakia.

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http://dx.doi.org/10.1016/s0003-9861(03)00003-1DOI Listing
March 2003