Publications by authors named "Rachel Kneen"

61Publications

Neurological associations of COVID-19.

Lancet Neurol 2020 09 2;19(9):767-783. Epub 2020 Jul 2.

National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; The Walton Centre National Health Service (NHS) Foundation Trust, Liverpool, UK; Tropical and Infectious Diseases Unit, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK. Electronic address:

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September 2020

Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.

Lancet Psychiatry 2020 10 25;7(10):875-882. Epub 2020 Jun 25.

The National Institute for Health Research Health Protection Research Unit for Emerging and Zoonotic Infections, Liverpool, UK; Department of Clinical Infection Microbiology and Immunology, Institute of Infection, Veterinary, and Ecological Sciences, University of Liverpool, Liverpool, UK; The Walton Centre NHS Foundation Trust, Liverpool, UK. Electronic address:

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October 2020

Seizures and quinolone antibiotics in children: a systematic review of adverse events.

Eur J Hosp Pharm 2020 03 28;27(2):60-64. Epub 2019 Jan 28.

Department of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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March 2020

A pragmatic cluster randomised controlled trial of a tailored intervention to improve the initial management of suspected encephalitis.

PLoS One 2018 6;13(12):e0202257. Epub 2018 Dec 6.

Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.

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April 2019

Clinical features, course, and outcomes of a UK cohort of pediatric moyamoya.

Neurology 2018 02;90(9):e763-e770

From the Clinical Neurosciences Section (S.C.T.-C., F.K., V.G.), UCL Great Ormond Street Institute of Child Health; Neurosurgery Department (D.T.) and Neurology Department (D.S., V.G.), Great Ormond Street Hospital for Children NHS Foundation Trust, London; Neurology Department (S.A.), Birmingham Children's Hospital NHS Foundation Trust; Institute of Neuroscience (A.B.), Newcastle University; Department of Paediatric Neurology (A.B.), Newcastle upon Tyne Hospitals NHS Foundation Trust; Department of Paediatric Neurology (M.C.), Cambridge University Hospitals NHS Foundation Trust; Department of Paediatric Neurology (G.C.), Nottingham University Hospitals NHS Foundation Trust; Department of Paediatric Neurology (F.G.), University Hospital of Wales; Neurology Department (A.H.), Sheffield Children's Hospital NHS Foundation Trust; Neurology Department (K.K.T.), Royal Hospital for Sick Children, Edinburgh; Department of Paediatric Neurology (F.K.), University Hospital Southampton NHS Foundation Trust; Neurology Department (R.K.), Alder Hey Children's NHS Foundation Trust, Liverpool; Department of Paediatric Neurology (H.M.), The Leeds Teaching Hospitals NHS Trust; Department of Paediatric Neurology (L.M.), St Mary's Hospital, Imperial College Healthcare NHS Trust, London; Neurology Department (G.V.), Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust; Neurology Department (K.V.), Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust; Neurology Department (E.W.), Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK; and Department of Paediatrics (T.H.Y.), KK Women's and Children's Hospital, Singapore.

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February 2018

Clinical and molecular characterization of -related severe early-onset epilepsy.

Neurology 2018 01 1;90(1):e55-e66. Epub 2017 Dec 1.

From Molecular Neurosciences (A.M., E.M., A., A.N., M.A.K.), Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health; Department of Neurology (A.M., A., A.N., C.E., J.H.C., M.A.K.) and Neuroradiology (W.K.C.), Great Ormond Street Hospital for Children, London, UK; Florey Institute of Neuroscience and Mental Health (U.N., E.V.G., I.E.S., S.P.), Melbourne, Australia; Department of Biological Sciences (S.M., M.T.), Institute of Structural and Molecular Biology, Birkbeck College, University of London; Regional Molecular Genetics Laboratory (N.T., R.H.S.), North East Thames Regional Genetics Service, and Department of Clinical Genetics (A.V.K., R.H.S.), Great Ormond Street Hospital, London, UK; Department of Paediatric Neurology (S.A.), Red Cross War Memorial Children's Hospital, Cape Town, South Africa; Department of Paediatric Neurology (G.A.), Addenbrooke's Hospital, Cambridge; Roald Dahl EEG Unit (R.A.), Department of Neurology, and Department of Neurology (R.K.), Alder Hey Children's Hospital, Liverpool; Department of Paediatric Neurology (A.D.), Sheffield Children's Hospital; Clinical Neurosciences (C.E., J.H.C.), Developmental Neurosciences, UCL Great Ormond Street Institute of Child Health, London; Institute of Infection and Global Health (R.K.), University of Liverpool; Department of Paediatric Neurology (K.L.), Evelina Children's Hospital, Guys and St. Thomas' NHS Foundation Trust, London; Department of Clinical Genetics (T.M.), Northern Genetics Service; Department of Pediatric Neurology (V.R.), Great North Children's Hospital, Newcastle Upon Tyne; Department of Paediatric Neurology (R.S.), University Hospital Leicester Children's Hospital; Department of Paediatric Neurology (J.T.), Royal Manchester Children's Hospital; Department of Paediatric Neurology (W.W.), Nottingham University Hospitals NHS Trust, UK; Epilepsy Genetics Program (A. Poduri), Department of Neurology, Boston Children's Hospital; Department of Neurology (A. Poduri), Harvard Medical School, Boston, MA; University of Melbourne (I.E.S.), Austin Health and Royal Children's Hospital, Australia; and Department of Medicine (S.P.), Royal Melbourne Hospital, University of Melbourne, Australia. Dr. Malhotra is currently at the Department of Biochemistry, University of Cambridge, UK.

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January 2018

The inter-rater reliability and prognostic value of coma scales in Nepali children with acute encephalitis syndrome.

Paediatr Int Child Health 2018 02 16;38(1):60-65. Epub 2017 Nov 16.

a Institute of Infection and Global Health , University of Liverpool , Liverpool , UK.

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February 2018

Current evidence-based recommendations on investigating children with global developmental delay.

Arch Dis Child 2017 11;102(11):1071-1076

Department of Developmental Paediatrics, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

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November 2017

Care beyond the hospital ward: understanding the socio-medical trajectory of herpes simplex virus encephalitis.

BMC Health Serv Res 2017 Sep 12;17(1):646. Epub 2017 Sep 12.

Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.

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September 2017

Subdural Empyema Caused by Neisseria meningitidis: A Case Report and Review of the Literature.

Pediatr Infect Dis J 2016 10;35(10):1156-9

From the *Littlewoods Neurosciences Unit, Alder Hey Children's NHS Foundation Trust; †Institute of Infection and Global Health, University of Liverpool; ‡Department of Paediatric Infectious Diseases and Immunology, §Department of Radiology, ¶Department of Paediatric Neurosurgery, Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom; ‖Department of Paediatrics, Wrexham Maelor Hospital, Wrexham, United Kingdom; **Walton Centre NHS Foundation Trust; and ††National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.

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October 2016

Diagnostic Pathways as Social and Participatory Practices: The Case of Herpes Simplex Encephalitis.

PLoS One 2016 9;11(3):e0151145. Epub 2016 Mar 9.

Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.

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August 2016

Herpesvirus Infections and Childhood Arterial Ischemic Stroke: Results of the VIPS Study.

Circulation 2016 Feb 26;133(8):732-41. Epub 2016 Jan 26.

From Department of Neurology Columbia University, New York, NY (M.S.V.E.); Department of Epidemiology, Mailman School of Public Health, New York, NY (M.S.V.E.); Departments of Neurology (N.K.H., H.J.F.), Biostatistics & Epidemiology (N.K.H.), and Pediatrics (C.A.G., H.J.F.), University of California San Francisco, San Francisco, CA; Department of Pediatrics (Infectious Disease), Kaiser Permanente, Oakland, CA (C.A.G.); Departments of Pediatrics and Neurology, Ohio State University, Columbus OH (W.D.L.); Department of Neurology, University of Washington, Seattle, WA (C.A.-L,); Department of Neurology, Hospital for Sick Children, Toronto, Canada (N.D., G.A.deV.); Department of Neurology, Alder Hey Children's NHS Foundation Trust, Liverpool, England (R.K.); Department of Pathology, Columbia University, New York, NY (E.A.H.); and Department of Radiology, Stanford University, Palo Alto, CA (M.W.).

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February 2016

Anti-N-Methyl-D-Aspartate Receptor Encephalitis In A Young Child With Histological Evidence On Brain Biopsy Of Coexistent Herpes Simplex Virus Type 1 Infection.

Pediatr Infect Dis J 2016 Mar;35(3):347-9

From the *Institute of Infection and Global Health, University of Liverpool; †Alder Hey Children's NHS Foundation Trust; ‡The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom; §Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital; and ¶Department of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.

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March 2016

Managing patients with encephalitis.

Nurs Stand 2015 Nov;30(11):50-8; quiz 60

Institute of Infection and Global Health, University of Liverpool and Alder Hey Children's Hospital NHS Foundation Trust, Liverpool, England.

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November 2015

Performing lumbar punctures for suspected CNS infections: experience and practice of trainee doctors.

Br J Hosp Med (Lond) 2015 Nov;76(11):658-62

Consultant Paediatric Neurologist, Alder Hey Children's NHS Foundation Trust, Liverpool and Honorary Senior Clinical Lecturer in the Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool L69 7BE.

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November 2015

The development of an intervention to promote adherence to national guidelines for suspected viral encephalitis.

Implement Sci 2015 Mar 20;10:37. Epub 2015 Mar 20.

Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Ronald Ross Building, 8 West Derby Street, Liverpool, L69 7BE, UK.

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March 2015

A preliminary randomized double blind placebo-controlled trial of intravenous immunoglobulin for Japanese encephalitis in Nepal.

PLoS One 2015 17;10(4):e0122608. Epub 2015 Apr 17.

Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom; The Walton Centre National Health Service Foundation Trust, Liverpool, United Kingdom; National Consortium for Zoonosis Research, Liverpool, United Kingdom; National Institute for Health Research-Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.

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January 2016

The evaluation of a tailored intervention to improve the management of suspected viral encephalitis: protocol for a cluster randomised controlled trial.

Implement Sci 2015 Jan 27;10:14. Epub 2015 Jan 27.

Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Ronald Ross Building, 8 West Derby Street, Liverpool, L69 7BE, United Kingdom.

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January 2015

IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study.

Neurology 2015 Jan 24;84(4):382-90. Epub 2014 Dec 24.

From the Departments of Molecular and Clinical Pharmacology (G.A.B.), Biostatistics (C.P.C., M.G.-F.), and Clinical Psychology (R.S.), Institute of Infection and Global Health (M.J.C., A.G.), and Alder Hey Children's Hospital & Institute of Infection & Global Health (R.K.), University of Liverpool; Institute of Human Development (R.L.B., J.C.-S.), University of Manchester; Manchester Academic Health Sciences Centre (R.L.B., M.B., G.M., J.C.-S.), Central Manchester University Hospitals Foundation Trust, UK; Department of Neurology (M.J.C.), Georgia Regents University, Augusta; Department of Neurology & Pediatrics (D.W.L.), Emory University, Atlanta, GA; and Department of Neurology & Neurological Sciences (K.J.M.), Stanford University, CA.

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January 2015

Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease.

Neurology 2014 Jul 11;83(2):142-50. Epub 2014 Jun 11.

From the Neuroimmunology Group (R.C.D., F.B.), Children's Hospital at Westmead, University of Sydney, Australia; Boston Children's Hospital (L.V.D., M.P.G.), MA; the Division of Rheumatology (M.T., S.M.B.), The Hospital for Sick Children, University of Toronto, Canada; Children's Hospital of Philadelphia (A.T.W., S.N., B.B.), University of Pennsylvania; Paediatric Neurology and Rheumatology (E.M., A.S.), Texas Children's Hospital, Baylor College of Medicine, Houston; Assistance Publique-Hopitaux de Paris (K.D., M.T.), Hôpitaux Universitaires Paris-Sud, National Referral Center for Neuro-Inflammatory Diseases in Children, Pediatric Neurology Department and Université Paris-Sud, Inserm U1012, Le Kremlin-Bicêtre, France; Royal Children's Hospital Melbourne (E.A., A.K.), Australia; Great Ormond Street Hospital NHS Trust (M.R.E., C.H.), London; UCL Institute of Child Health (D.E., P.A.B.), London; Alder Hey Children's NHS Foundation Trust and the Institute of Infection and Global Health (R.K.), University of Liverpool, UK; Children's Hospital of Pittsburgh (G.A.), University of Pittsburgh, PA; Hacettepe University Child Neurology (B.A.), Turkey; Birmingham Children's Hospital (E.W.); John Radcliffe Hospital (K.H.), Oxford, UK; Neurosciences Unit and Mater Medical Research Institute (C.J.R.), Mater Children's Hospital, South Brisbane, University of Queensland, Australia; Alberta Children's Hospital (S.M.B.), Calgary, University of Calgary, Canada; and Evelina Children's Hospital (M.L.), London, UK.

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July 2014

Benign hereditary chorea related to NKX2.1: expansion of the genotypic and phenotypic spectrum.

Dev Med Child Neurol 2014 Jul 31;56(7):642-8. Epub 2013 Oct 31.

MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine & Clinical Neurosciences, Cardiff University, Cardiff, UK.

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July 2014

The functional, social and economic impact of acute encephalitis syndrome in Nepal--a longitudinal follow-up study.

PLoS Negl Trop Dis 2013 12;7(9):e2383. Epub 2013 Sep 12.

Brain Infections Group, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom ; Department of Paediatric Neurology, Alder Hey Children's National Health Service Foundation Trust, Liverpool, United Kingdom.

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March 2014

Limbic encephalitis associated with elevated antithyroid antibodies.

J Child Neurol 2014 Jun 20;29(6):769-73. Epub 2013 Mar 20.

Children's Neurosciences Center, Evelina Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, King's Health Partners Academic Health Sciences Centre, London, UK Nuffield Department of Clinical Neurosciences, West Wing, John Radcliffe Hospital, University of Oxford, Oxford, UK

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June 2014

Suboptimal management of central nervous system infections in children: a multi-centre retrospective study.

BMC Pediatr 2012 Sep 7;12:145. Epub 2012 Sep 7.

Neurological Infectious Disease, Brain Infections Group, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.

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September 2012

Congenital trigeminal anaesthesia: a rare preventable cause of visual loss in children.

BMJ Case Rep 2012 Jul 3;2012. Epub 2012 Jul 3.

Littlewood Neurosciences Unit, Department of Ophthalmology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

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July 2012

Childhood presentation of COL4A1 mutations.

Dev Med Child Neurol 2012 Jun 16;54(6):569-74. Epub 2012 Jan 16.

Department of Paediatric Neurology, Bristol Royal Hospital for Children, Bristol, UK.

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June 2012

Sulthiame in refractory paediatric epilepsies: an experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit.

Seizure 2011 Dec 15;20(10):805-8. Epub 2011 Sep 15.

Alder Hey Children's NHS Foundation Trust, Eaton Road, West Derby, Liverpool L12 2AP, United Kingdom.

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December 2011

Encephalitis in children.

Arch Dis Child 2012 Feb 28;97(2):150-61. Epub 2011 Jun 28.

Department of Paediatrics, University of Oxford, Level 2 Children's Hospital, Oxford OX3 9DU, UK.

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February 2012

Effectiveness and tolerability of zonisamide in children with epilepsy: a retrospective review.

Seizure 2010 Jan 25;19(1):31-5. Epub 2009 Nov 25.

Department of Paediatric Neurology, Royal Manchester Children's Hospital, Oxford Road, Manchester M13 9WL, UK.

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January 2010

Anterior spinal artery syndrome in a girl with Down syndrome: case report and literature review.

J Spinal Cord Med 2009 ;32(3):349-54

Department of Paediatric Neurology, Royal Liverpool Children's Hospital, Liverpool, United Kingdom.

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October 2009

The management of infants and children treated with aciclovir for suspected viral encephalitis.

Arch Dis Child 2010 Feb 19;95(2):100-6. Epub 2009 May 19.

Department of Neurology, Littlewood's Neuroscience Unit, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

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February 2010

Successful treatment of cytomegalovirus polyradiculopathy in a 9-year-old child with congenital human immunodeficiency virus infection.

J Child Neurol 2009 Feb;24(2):215-8

Department of Neurology, Littlewoods Neuroscience Foundation, Royal Liverpool Children's NHS Trust, Alder Hey, Liverpool, United Kingdom.

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February 2009

Chiari I malformation without hydrocephalus: acute intracranial hypertension managed with endoscopic third ventriculostomy (ETV).

Childs Nerv Syst 2008 Dec 15;24(12):1493-7. Epub 2008 Jul 15.

Department of Neurosurgery, Royal Liverpool Children's NHS Trust, Eaton Rd, Liverpool, L12 2AP, UK.

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December 2008

A cohort study to assess the new WHO Japanese encephalitis surveillance standards.

Bull World Health Organ 2008 Mar;86(3):178-86

Viral Brain Infections Group, Divisions of Neurological Science, and Medical Microbiology, School of Tropical Medicine, University of Liverpool, Liverpool L9 7LJ, England.

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March 2008

Clinical features and predictors of diphtheritic cardiomyopathy in Vietnamese children.

Clin Infect Dis 2004 Dec 8;39(11):1591-8. Epub 2004 Nov 8.

Wellcome Trust Clinical Research Unit, Centre for Tropical Diseases, Cho Quan Hospital, Ho Chi Minh City, Vietnam.

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December 2004

The role of lumbar puncture in children with suspected central nervous system infection.

BMC Pediatr 2002 Sep 2;2. Epub 2002 Sep 2.

The Roald Dahl EEG Unit, Royal Liverpool Children's NHS Trust, Alder Hey, Liverpool, L12 2AP, UK.

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September 2002