Rachael I Scahill

Rachael I Scahill

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Rachael I Scahill

Rachael I Scahill

Publications by authors named "Rachael I Scahill"

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Multimodal characterization of the visual network in Huntington's disease gene carriers.

Clin Neurophysiol 2019 Nov 28;130(11):2053-2059. Epub 2019 Aug 28.

Department of Neurology, Ulm University Hospital, Ulm, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clinph.2019.08.018DOI Listing
November 2019

Cerebrospinal fluid flow dynamics in Huntington's disease evaluated by phase contrast MRI.

Eur J Neurosci 2019 Jun 19;49(12):1632-1639. Epub 2019 Feb 19.

UCL Huntington's Disease Centre, UCL Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1111/ejn.14356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618296PMC
June 2019

Fluid and imaging biomarkers for Huntington's disease.

Mol Cell Neurosci 2019 Jun 23;97:67-80. Epub 2019 Feb 23.

Huntington's Disease Centre, University College London (UCL) Institute of Neurology, London WC1N 3BG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.mcn.2019.02.004DOI Listing
June 2019

Functional Magnetic Resonance Imaging in Huntington's Disease.

Int Rev Neurobiol 2018 29;142:381-408. Epub 2018 Oct 29.

Huntington's Disease Research Centre, UCL Institute of Neurology, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/bs.irn.2018.09.013DOI Listing
May 2019

Magnetic Resonance Imaging in Huntington's Disease.

Methods Mol Biol 2018 ;1780:303-328

Huntington's Disease Research Centre, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1007/978-1-4939-7825-0_16DOI Listing
February 2019

Automated Segmentation of Cortical Grey Matter from T1-Weighted MRI Images.

J Vis Exp 2019 Jan 7(143). Epub 2019 Jan 7.

Huntington's Disease Research Centre, UCL Institute of Neurology;

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http://dx.doi.org/10.3791/58198DOI Listing
January 2019

Altered Intracortical T-Weighted/T-Weighted Ratio Signal in Huntington's Disease.

Front Neurosci 2018 5;12:805. Epub 2018 Nov 5.

Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.3389/fnins.2018.00805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230564PMC
November 2018

In vivo characterization of white matter pathology in premanifest huntington's disease.

Ann Neurol 2018 10 15;84(4):497-504. Epub 2018 Sep 15.

Department of Computer Science and Centre for Medical Image Computing, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221120PMC
October 2018

An image-based model of brain volume biomarker changes in Huntington's disease.

Ann Clin Transl Neurol 2018 May 2;5(5):570-582. Epub 2018 Apr 2.

Department of Computer Science Centre for Medical Image Computing University College London Gower Street London WC1E 6BT United Kingdom.

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http://dx.doi.org/10.1002/acn3.558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945962PMC
May 2018

Structural imaging in premanifest and manifest Huntington disease.

Handb Clin Neurol 2017 ;144:247-261

Center for Integrative Brain Research, Seattle Children's Research Institute, University of Washington, Seattle, WA, United States.

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http://dx.doi.org/10.1016/B978-0-12-801893-4.00020-1DOI Listing
March 2018

Brain Regions Showing White Matter Loss in Huntington's Disease Are Enriched for Synaptic and Metabolic Genes.

Biol Psychiatry 2018 03 26;83(5):456-465. Epub 2017 Oct 26.

Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square, London, United Kingdom; National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2017.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803509PMC
March 2018

Predicting clinical diagnosis in Huntington's disease: An imaging polymarker.

Ann Neurol 2018 03 13;83(3):532-543. Epub 2018 Mar 13.

The Computational, Cognitive & Clinical Neuroimaging Laboratory (CNL), Division of Brain Sciences, Imperial College London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900832PMC
March 2018

Neurofilament light protein in blood predicts regional atrophy in Huntington disease.

Neurology 2018 02 24;90(8):e717-e723. Epub 2018 Jan 24.

From the Huntington's Disease Research Centre (E.B.J., L.M.B., S.G., F.B.R., S.J.T., R.I.S., E.J.W.), UCL Institute of Neurology, London, UK; Clinical Neurochemistry Laboratory (K.B., H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden; Institut du Cerveau et de la Moelle épinière (A.D.), Sorbonne Universités, UPMC University Paris 06, UMRS 1127, INSERM, U 1127, CNRS, UMR 7225; APHP (A.D.), Genetics Department, Pitié-Salpêtrière University Hospital, Paris, France; Centre for Molecular Medicine and Therapeutics (B.R.L.), University of British Columbia, Vancouver, BC, Canada; Department of Neurology (R.A.R.), Leiden University, the Netherlands; Department of Molecular Neuroscience (H.Z.), UCL Institute of Neurology, Queen Square, London, UK; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; and UK Dementia Research Institute (H.Z.), London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000005005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818166PMC
February 2018

Survival End Points for Huntington Disease Trials Prior to a Motor Diagnosis.

JAMA Neurol 2017 11;74(11):1352-1360

Huntington's Disease Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, Queen Square, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2017.2107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710578PMC
November 2017

Recommendations for the Use of Automated Gray Matter Segmentation Tools: Evidence from Huntington's Disease.

Front Neurol 2017 10;8:519. Epub 2017 Oct 10.

Huntington's Disease Centre, UCL Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fneur.2017.00519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641297PMC
October 2017

Neuropsychiatry and White Matter Microstructure in Huntington's Disease.

J Huntingtons Dis 2015 ;4(3):239-49

Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester and Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.3233/JHD-150160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684097PMC
July 2016

Short-interval observational data to inform clinical trial design in Huntington's disease.

J Neurol Neurosurg Psychiatry 2015 Dec 10;86(12):1291-8. Epub 2015 Feb 10.

Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1136/jnnp-2014-309768DOI Listing
December 2015

Increased central microglial activation associated with peripheral cytokine levels in premanifest Huntington's disease gene carriers.

Neurobiol Dis 2015 Nov 18;83:115-21. Epub 2015 Aug 18.

Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2015.08.011DOI Listing
November 2015

Huntington disease.

Nat Rev Dis Primers 2015 04 23;1:15005. Epub 2015 Apr 23.

Department of Neurodegenerative Disease, University College London Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1038/nrdp.2015.5DOI Listing
April 2015

Cerebellar abnormalities in Huntington's disease: a role in motor and psychiatric impairment?

Mov Disord 2014 Nov 13;29(13):1648-54. Epub 2014 Aug 13.

University College London, Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1002/mds.25984DOI Listing
November 2014

Inconsistent emotion recognition deficits across stimulus modalities in Huntington׳s disease.

Neuropsychologia 2014 11 22;64:99-104. Epub 2014 Sep 22.

University College London, Institute of Neurology, Queen Square, c/o Box 104, London WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuropsychologia.2014.09.023DOI Listing
November 2014

Longitudinal neuroimaging biomarkers in Huntington's Disease.

J Huntingtons Dis 2013 ;2(1):21-39

UCL Institute of Neurology, University College London, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JHD-120030DOI Listing
September 2014

Correction of inter-scanner and within-subject variance in structural MRI based automated diagnosing.

Neuroimage 2014 Sep 29;98:405-15. Epub 2014 Apr 29.

Freiburg Brain Imaging Center, University Medical Center, University of Freiburg, Freiburg, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany; Department of Neurology, University Medical Center Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.neuroimage.2014.04.057DOI Listing
September 2014

Biomarker development for Huntington's disease.

Drug Discov Today 2014 Jul 12;19(7):972-9. Epub 2014 Mar 12.

UCL Institute of Neurology, Department of Neurodegenerative Disease, Queen Square, London WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.03.002DOI Listing
July 2014

White matter integrity in premanifest and early Huntington's disease is related to caudate loss and disease progression.

Cortex 2014 Mar 6;52:98-112. Epub 2013 Dec 6.

National Hospital for Neurology and Neurosurgery, London, UK; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2013.11.009DOI Listing
March 2014

Test-Retest Reliability of Diffusion Tensor Imaging in Huntington's Disease.

PLoS Curr 2014 Mar 21;6. Epub 2014 Mar 21.

Huntington's Disease Research Group, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1371/currents.hd.f19ef63fff962f5cd9c0e88f4844f43bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962450PMC
March 2014

Biomarkers for Huntington's disease: an update.

Expert Opin Med Diagn 2012 Sep 24;6(5):371-5. Epub 2012 Jun 24.

UCL Institute of Neurology, TRACK-HD, Department of Neurodegenerative Disease , Queen Square, London WC1N 3BG , UK.

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http://dx.doi.org/10.1517/17530059.2012.701205DOI Listing
September 2012

The structural involvement of the cingulate cortex in premanifest and early Huntington's disease.

Mov Disord 2011 Aug 6;26(9):1684-90. Epub 2011 May 6.

Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.23747DOI Listing
August 2011

Early atrophy of pallidum and accumbens nucleus in Huntington's disease.

J Neurol 2011 Mar 9;258(3):412-20. Epub 2010 Oct 9.

Department of Neurology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00415-010-5768-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112014PMC
March 2011

Visuomotor integration deficits precede clinical onset in Huntington's disease.

Neuropsychologia 2011 Jan 20;49(2):264-70. Epub 2010 Nov 20.

UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1016/j.neuropsychologia.2010.11.016DOI Listing
January 2011

The progression of regional atrophy in premanifest and early Huntington's disease: a longitudinal voxel-based morphometry study.

J Neurol Neurosurg Psychiatry 2010 Jul 1;81(7):756-63. Epub 2009 Dec 1.

Dementia Research Centre, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1136/jnnp.2009.190702DOI Listing
July 2010

A meta-analysis of hippocampal atrophy rates in Alzheimer's disease.

Neurobiol Aging 2009 Nov 17;30(11):1711-23. Epub 2008 Mar 17.

Dementia Research Centre, University College London, Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2008.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773132PMC
November 2009

Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease.

J Neurol 2009 Feb 5;256(2):203-12. Epub 2009 Mar 5.

Dementia Research Centre, Institute of Neurology, University College, London, UK.

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http://dx.doi.org/10.1007/s00415-009-0052-xDOI Listing
February 2009

Defective emotion recognition in early HD is neuropsychologically and anatomically generic.

Neuropsychologia 2008 6;46(8):2152-60. Epub 2008 Mar 6.

Dementia Research Centre, Institute of Neurology, University College London, UK.

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http://dx.doi.org/10.1016/j.neuropsychologia.2008.02.025DOI Listing
August 2008

Accuracy assessment of global and local atrophy measurement techniques with realistic simulated longitudinal Alzheimer's disease images.

Neuroimage 2008 Aug 11;42(2):696-709. Epub 2008 May 11.

Centre for Medical Image Computing, Department of Medical Physics and Bioengineering, University College London, WC1E 6BT, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2008.04.259DOI Listing
August 2008

Ten simple rules for reporting voxel-based morphometry studies.

Neuroimage 2008 May 17;40(4):1429-35. Epub 2008 Jan 17.

Centre for Medical Image Computing, University College London, UK.

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http://core.ac.uk/download/pdf/1673493.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S105381190800043
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2008.01.003DOI Listing
May 2008

Automatic classification of MR scans in Alzheimer's disease.

Brain 2008 Mar 17;131(Pt 3):681-9. Epub 2008 Jan 17.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1093/brain/awm319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579744PMC
March 2008

Accuracy assessment of global and local atrophy measurement techniques with realistic simulated longitudinal data.

Med Image Comput Comput Assist Interv 2007 ;10(Pt 2):785-92

Centre for Medical Image Computing (CMIC), Department of Medical Physics and Bioengineering, University College London, London WC1E 6BT, UK.

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http://dx.doi.org/10.1007/978-3-540-75759-7_95DOI Listing
January 2008

Automated measurement of hippocampal atrophy using fluid-registered serial MRI in AD and controls.

J Comput Assist Tomogr 2007 Jul-Aug;31(4):581-7

Dementia Research Centre, University College London, Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1097/rct.0b013e31802f4139DOI Listing
October 2007

Simulation of local and global atrophy in Alzheimer's disease studies.

Med Image Comput Comput Assist Interv 2006 ;9(Pt 2):937-45

Center of Medical Image Computing, Unviersity College of London, UK.

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http://dx.doi.org/10.1007/11866763_115DOI Listing
April 2007

Atrophy rates of the cingulate gyrus and hippocampus in AD and FTLD.

Neurobiol Aging 2007 Jan 6;28(1):20-8. Epub 2006 Jan 6.

Dementia Research Centre, University College London, Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2005.11.012DOI Listing
January 2007

Phenomenological model of diffuse global and regional atrophy using finite-element methods.

IEEE Trans Med Imaging 2006 Nov;25(11):1417-30

Centre for Medical Image Computing (CMIC), Department of Medical Physics and Bioengineering, Department of Computer Science, University College London, London WCEI 6BT, UK.

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http://dx.doi.org/10.1109/TMI.2006.880588DOI Listing
November 2006

Does Alzheimer's disease affect hippocampal asymmetry? Evidence from a cross-sectional and longitudinal volumetric MRI study.

Dement Geriatr Cogn Disord 2005 22;19(5-6):338-44. Epub 2005 Mar 22.

Dementia Research Centre, Department of Clinical Neurology, Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1159/000084560DOI Listing
September 2005

Differentiating AD from aging using semiautomated measurement of hippocampal atrophy rates.

Neuroimage 2004 Oct;23(2):574-81

Dementia Research Centre, Institute of Neurology, University College London, 8-11 Queen Square, WCIN 3BG, London, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S105381190400338
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2004.06.028DOI Listing
October 2004

Longitudinal patterns of regional change on volumetric MRI in frontotemporal lobar degeneration.

Dement Geriatr Cogn Disord 2004 ;17(4):307-10

Dementia Research Group, Institute of Neurology, University College London and Imperial College London, London, UK.

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http://dx.doi.org/10.1159/000077160DOI Listing
September 2004

A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging.

Arch Neurol 2003 Jul;60(7):989-94

Dementia Research Group, Department of Clinical Neurology, Institute of Neurology, University College London, England.

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http://dx.doi.org/10.1001/archneur.60.7.989DOI Listing
July 2003

Assessing the onset of structural change in familial Alzheimer's disease.

Ann Neurol 2003 Feb;53(2):181-8

Dementia Research Group, Institute of Neurology, University College London, Queen Square, United Kingdom.

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http://dx.doi.org/10.1002/ana.10424DOI Listing
February 2003

Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias.

Neuroimage 2002 Sep;17(1):29-46

Wellcome Department of Cognitive Neurology, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom.

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September 2002

Mapping the evolution of regional atrophy in Alzheimer's disease: unbiased analysis of fluid-registered serial MRI.

Proc Natl Acad Sci U S A 2002 Apr;99(7):4703-7

Dementia Research Group, Department of Clinical Neurology, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, United Kingdom.

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http://dx.doi.org/10.1073/pnas.052587399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123711PMC
April 2002