Ronald Sluyter

Ronald Sluyter

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Ronald Sluyter

Publications by authors named "Ronald Sluyter"

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Increased splenic human CD4:CD8 T cell ratios, serum human interferon-γ and intestinal human interleukin-17 are associated with clinical graft-versus-host disease in humanized mice.

Transpl Immunol 2019 06 8;54:38-46. Epub 2019 Feb 8.

School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2252, Australia; Molecular Horizons, University of Wollongong, Wollongong, NSW 2252, Australia; Illawarra Health and Medical Research Institute, Wollongong, NSW 2252, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.trim.2019.02.003DOI Listing
June 2019

Pharmacological blockade of the CD39/CD73 pathway but not adenosine receptors augments disease in a humanized mouse model of graft-versus-host disease.

Immunol Cell Biol 2019 Apr 7. Epub 2019 Apr 7.

School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, NSW, 2252, Australia.

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http://dx.doi.org/10.1111/imcb.12251DOI Listing
April 2019

The P2X7 Receptor.

Authors:
Ronald Sluyter

Adv Exp Med Biol 2017 ;1051:17-53

School of Biological Sciences, University of Wollongong, Wollongong, NSW, 2522, Australia.

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http://dx.doi.org/10.1007/5584_2017_59DOI Listing
June 2018

The P2X7 receptor is not essential for development of imiquimod-induced psoriasis-like inflammation in mice.

Purinergic Signal 2017 12 8;13(4):405-415. Epub 2017 Jun 8.

School of Biological Sciences, University of Wollongong, Wollongong, NSW, Australia.

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http://dx.doi.org/10.1007/s11302-017-9569-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714832PMC
December 2017

Probenecid directly impairs activation of the canine P2X7 receptor.

Nucleosides Nucleotides Nucleic Acids 2017 Dec 4;36(12):736-744. Epub 2017 Dec 4.

a School of Biological Sciences, University of Wollongong , Wollongong , NSW , Australia.

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http://dx.doi.org/10.1080/15257770.2017.1391395DOI Listing
December 2017

On-Chip Microparticle and Cell Washing Using Coflow of Viscoelastic Fluid and Newtonian Fluid.

Anal Chem 2017 09 17;89(17):9574-9582. Epub 2017 Aug 17.

School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong , Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1021/acs.analchem.7b02671DOI Listing
September 2017

N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages.

Mediators Inflamm 2016 21;2016:2097219. Epub 2016 Jul 21.

School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia; Centre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1155/2016/2097219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972911PMC
June 2017

P2X7 receptor antagonism in amyotrophic lateral sclerosis.

Neural Regen Res 2017 May;12(5):749-750

School of Biological Sciences and Center for Medical and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia; Illawarra Health and Medical Research Institute, NSW, Wollongong, Australia.

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http://dx.doi.org/10.4103/1673-5374.206643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461610PMC
May 2017

P2X7 antagonism using Brilliant Blue G reduces body weight loss and prolongs survival in female SOD1 amyotrophic lateral sclerosis mice.

PeerJ 2017 1;5:e3064. Epub 2017 Mar 1.

Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia; School of Biological Sciences, University of Wollongong, Wollongong, NSW, Australia; Centre for Medical and Molecular Biosciences, Wollongong, NSW, Australia.

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http://dx.doi.org/10.7717/peerj.3064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335685PMC
March 2017

Roles of extracellular nucleotides and P2 receptors in ectodomain shedding.

Cell Mol Life Sci 2016 11 14;73(22):4159-4173. Epub 2016 May 14.

School of Biological Sciences, University of Wollongong, Wollongong, NSW, 2522, Australia.

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http://dx.doi.org/10.1007/s00018-016-2274-2DOI Listing
November 2016

Continuous plasma extraction under viscoelastic fluid in a straight channel with asymmetrical expansion-contraction cavity arrays.

Lab Chip 2016 10;16(20):3919-3928

School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1039/c6lc00843gDOI Listing
October 2016

Editorial: Roles of Ion Channels in Immune Cells.

Front Immunol 2016 15;7:48. Epub 2016 Feb 15.

School of Biological Sciences, University of Wollongong, Wollongong, NSW, Australia; Centre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, NSW, Australia; Illawarra Health and Medical Research Institute, Wollongong, NSW, Australia.

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http://dx.doi.org/10.3389/fimmu.2016.00048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753291PMC
February 2016

P2X and P2Y receptor signaling in red blood cells.

Authors:
Ronald Sluyter

Front Mol Biosci 2015 28;2:60. Epub 2015 Oct 28.

School of Biological Sciences, University of Wollongong Wollongong, NSW, Australia ; Centre for Medical and Molecular Bioscience, University of Wollongong Wollongong, NSW, Australia ; Illawarra Health and Medical Research Institute Wollongong, NSW, Australia.

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http://dx.doi.org/10.3389/fmolb.2015.00060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623207PMC
November 2015

Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism.

PLoS One 2014 26;9(3):e93058. Epub 2014 Mar 26.

Sydney Medical School Nepean, University of Sydney, Nepean Hospital, Penrith, New South Wales, Australia; Health Innovations Research Institute, School of Medical Sciences, RMIT University, Bundoora, Melbourne, Victoria, Australia.

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https://pdfs.semanticscholar.org/ea5f/8efcc232e4ed378d91b8b2
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http://dx.plos.org/10.1371/journal.pone.0093058
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093058PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966854PMC
June 2015

Activation of the P2X7 receptor induces the rapid shedding of CD23 from human and murine B cells.

Immunol Cell Biol 2015 Jan 26;93(1):77-85. Epub 2014 Aug 26.

1] School of Biological Sciences, University of Wollongong, Wollongong, New South Wales, Australia [2] Illawarra Health and Medical Research Institute, Wollongong, New South Wales, Australia.

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http://dx.doi.org/10.1038/icb.2014.69DOI Listing
January 2015

An investigation into the interactions of gold nanoparticles and anti-arthritic drugs with macrophages, and their reactivity towards thioredoxin reductase.

J Inorg Biochem 2015 Jan 28;142:28-38. Epub 2014 Sep 28.

Centre for Medical and Molecular Bioscience, University of Wollongong, Wollongong, NSW 2522, Australia; School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jinorgbio.2014.09.013DOI Listing
January 2015

R270C polymorphism leads to loss of function of the canine P2X7 receptor.

Physiol Genomics 2014 Jul 13;46(14):512-22. Epub 2014 May 13.

School of Biological Sciences, University of Wollongong, Wollongong, Australia; Illawarra Health and Medical Research Institute, Wollongong, Australia;

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http://dx.doi.org/10.1152/physiolgenomics.00195.2013DOI Listing
July 2014

The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease.

Pharmacol Rev 2014 Jul;66(3):638-75

School of Biological Sciences, University of Wollongong, New South Wales, Australia and Illawarra Health and Medical Research Institute, Wollongong, New South Wales, Australia (R.B., R.S.); and Health Innovations Research Institute, School of Medical Sciences, RMIT University, Bundoora, Victoria, Australia (L.S.)

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http://pharmrev.aspetjournals.org/cgi/doi/10.1124/pr.113.008
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http://dx.doi.org/10.1124/pr.113.008003DOI Listing
July 2014

On-chip high-throughput manipulation of particles in a dielectrophoresis-active hydrophoretic focuser.

Sci Rep 2014 May 27;4:5060. Epub 2014 May 27.

School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1038/srep05060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033927PMC
May 2014

Inertial particle separation by differential equilibrium positions in a symmetrical serpentine micro-channel.

Sci Rep 2014 Mar 31;4:4527. Epub 2014 Mar 31.

Queensland Micro and Nanotechnology Centre, Griffith University, Brisbane QLD 4111, Australia.

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http://dx.doi.org/10.1038/srep04527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970124PMC
March 2014

Extracellular adenosine 5'-triphosphate and lipopolysaccharide induce interleukin-1β release in canine blood.

Vet Immunol Immunopathol 2014 Jan 8;157(1-2):105-10. Epub 2013 Nov 8.

School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia; Illawarra Health and Medical Research Institute, Wollongong, NSW 2522, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.vetimm.2013.11.002DOI Listing
January 2014

P2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microglia.

Mediators Inflamm 2013 27;2013:271813. Epub 2013 Jan 27.

School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1155/2013/271813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568910PMC
August 2013

P2X7 receptor activation induces reactive oxygen species formation in erythroid cells.

Purinergic Signal 2013 Mar 27;9(1):101-12. Epub 2012 Sep 27.

School of Biological Sciences, University of Wollongong, Wollongong, NSW, 2522, Australia.

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http://dx.doi.org/10.1007/s11302-012-9335-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568428PMC
March 2013

Human P2X7 receptor activation induces the rapid shedding of CXCL16.

Biochem Biophys Res Commun 2013 Mar 18;432(4):626-31. Epub 2013 Feb 18.

School of Biological Sciences, University of Wollongong, Wollongong, NSW, Australia.

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http://dx.doi.org/10.1016/j.bbrc.2013.01.134DOI Listing
March 2013

P2X7 receptor activation mediates organic cation uptake into human myeloid leukaemic KG-1 cells.

Purinergic Signal 2012 Dec 5;8(4):669-76. Epub 2012 Jun 5.

School of Biological Sciences, University of Wollongong, Wollongong, NSW, 2522, Australia.

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http://dx.doi.org/10.1007/s11302-012-9320-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486171PMC
December 2012

Functional expression of the damage-associated molecular pattern receptor P2X7 on canine kidney epithelial cells.

Vet Immunol Immunopathol 2012 Dec 4;150(3-4):228-33. Epub 2012 Oct 4.

School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1016/j.vetimm.2012.09.040DOI Listing
December 2012

Activation of the damage-associated molecular pattern receptor P2X7 induces interleukin-1β release from canine monocytes.

Vet Immunol Immunopathol 2012 Sep 8;149(1-2):86-91. Epub 2012 May 8.

School of Biological Sciences, University of Wollongong, Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1016/j.vetimm.2012.05.004DOI Listing
September 2012

Significance of P2X7 receptor variants to human health and disease.

Recent Pat DNA Gene Seq 2011 Apr;5(1):41-54

School of Biological Sciences, University of Wollongong, Wollongong, NSW, Australia.

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April 2011

P2X7 receptor activation induces cell death and CD23 shedding in human RPMI 8226 multiple myeloma cells.

Biochim Biophys Acta 2010 Nov 18;1800(11):1173-82. Epub 2010 Jul 18.

School of Biological Sciences, University of Wollongong, Wollongong, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.bbagen.2010.07.001DOI Listing
November 2010

TGF-β1 prevents up-regulation of the P2X7 receptor by IFN-γ and LPS in leukemic THP-1 monocytes.

Biochim Biophys Acta 2010 Nov 27;1798(11):2058-66. Epub 2010 Jul 27.

School of Biological Sciences, University of Wollongong, Wollongong, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.bbamem.2010.07.022DOI Listing
November 2010

P2X7 receptor activation induces cell death and microparticle release in murine erythroleukemia cells.

Biochim Biophys Acta 2010 Sep 8;1798(9):1797-804. Epub 2010 Jun 8.

School of Biological Sciences, University of Wollongong, Wollongong, Australia.

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http://dx.doi.org/10.1016/j.bbamem.2010.06.002DOI Listing
September 2010

Murine epidermal Langerhans cells and keratinocytes express functional P2X7 receptors.

Exp Dermatol 2010 Aug;19(8):e151-7

Department of Medicine, Nepean Clinical School, University of Sydney, Penrith, NSW, Australia.

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http://dx.doi.org/10.1111/j.1600-0625.2009.01029.xDOI Listing
August 2010

Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion.

FASEB J 2010 Aug 1;24(8):2916-27. Epub 2010 Apr 1.

Department of Medicine, University of Sydney, Nepean Clinical School, Nepean Hospital, Penrith, New South Wales, Australia.

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http://dx.doi.org/10.1096/fj.09-150862DOI Listing
August 2010

The P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types.

Purinergic Signal 2009 Sep 16;5(3):385-94. Epub 2009 Jun 16.

Department of Medicine, Nepean Clinical School, University of Sydney, Penrith, NSW, Australia.

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http://dx.doi.org/10.1007/s11302-009-9163-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717320PMC
September 2009

"Host tissue damage" signal ATP impairs IL-12 and IFNgamma secretion in LPS stimulated whole human blood.

Intensive Care Med 2008 Oct 3;34(10):1891-7. Epub 2008 Jun 3.

Department of Intensive Care, Nepean Hospital, University of Sydney, P.O. Box 63, Penrith, NSW 2750, Australia.

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http://dx.doi.org/10.1007/s00134-008-1156-yDOI Listing
October 2008

Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist.

Biochem Biophys Res Commun 2008 Jan 20;365(3):515-20. Epub 2007 Nov 20.

Department of Medicine, Nepean Clinical School, University of Sydney, Penrith, NSW, Australia.

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http://dx.doi.org/10.1016/j.bbrc.2007.11.008DOI Listing
January 2008

Canine erythrocytes express the P2X7 receptor: greatly increased function compared with human erythrocytes.

Am J Physiol Regul Integr Comp Physiol 2007 Nov 29;293(5):R2090-8. Epub 2007 Aug 29.

Dept. of Medicine, University of Sydney, Nepean Clinical School, Penrith, New South Wales, Australia.

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http://dx.doi.org/10.1152/ajpregu.00166.2007DOI Listing
November 2007

A quantitative method for routine measurement of cell surface P2X7 receptor function in leucocyte subsets by two-colour time-resolved flow cytometry.

J Immunol Methods 2007 Aug 26;325(1-2):67-77. Epub 2007 Jun 26.

Department of Medicine, the University of Sydney, Nepean Hospital, Penrith, New South Wales 2750, Australia.

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http://dx.doi.org/10.1016/j.jim.2007.06.002DOI Listing
August 2007

P2X(7) receptor activation causes phosphatidylserine exposure in human erythrocytes.

Biochem Biophys Res Commun 2007 Mar 30;355(1):169-73. Epub 2007 Jan 30.

Department of Medicine, Nepean Clinical School, University of Sydney, Penrith, NSW, Australia.

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http://dx.doi.org/10.1016/j.bbrc.2007.01.124DOI Listing
March 2007

A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis.

Am J Respir Crit Care Med 2007 Feb 9;175(4):360-6. Epub 2006 Nov 9.

Mycobacterial Research Programme, Centenary Institute of Cancer Medicine and Cell Biology, Locked Bag No 6, Newtown, NSW, Australia.

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http://dx.doi.org/10.1164/rccm.200607-970OCDOI Listing
February 2007

Rottlerin inhibits P2X(7) receptor-stimulated phospholipase D activity in chronic lymphocytic leukaemia B-lymphocytes.

Immunol Cell Biol 2007 Jan 28;85(1):68-72. Epub 2006 Nov 28.

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, New South Wales, Australia.

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http://doi.wiley.com/10.1038/sj.icb.7100005
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http://dx.doi.org/10.1038/sj.icb.7100005DOI Listing
January 2007

Human epidermal and monocyte-derived langerhans cells express functional P2X receptors.

J Invest Dermatol 2005 Sep;125(3):482-90

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, NSW, Australia.

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http://dx.doi.org/10.1111/j.0022-202X.2005.23835.xDOI Listing
September 2005

A 5' intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1-2% of the Caucasian population.

FEBS Lett 2005 May 14;579(12):2675-8. Epub 2005 Apr 14.

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, NSW, Australia.

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http://dx.doi.org/10.1016/j.febslet.2005.03.091DOI Listing
May 2005

Extracellular ATP increases cation fluxes in human erythrocytes by activation of the P2X7 receptor.

J Biol Chem 2004 Oct 10;279(43):44749-55. Epub 2004 Aug 10.

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, New South Wales 2750, Australia.

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http://dx.doi.org/10.1074/jbc.M405631200DOI Listing
October 2004

An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor.

J Biol Chem 2004 Jul 27;279(30):31287-95. Epub 2004 Apr 27.

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, New South Wales 2750, Australia.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M313902200
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http://dx.doi.org/10.1074/jbc.M313902200DOI Listing
July 2004

Chelerythrine and other benzophenanthridine alkaloids block the human P2X7 receptor.

Br J Pharmacol 2004 Jul 21;142(6):1015-9. Epub 2004 Jun 21.

Department of Medicine, The University of Sydney at Nepean Hospital, Penrith, NSW, 2751, Australia.

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http://dx.doi.org/10.1038/sj.bjp.0705868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575114PMC
July 2004

CXCR4 but not CXCR3 expression correlates with lymphocyte counts in B-cell chronic lymphocytic leukemia.

Ann Hematol 2004 May 18;83(5):326-7. Epub 2004 Feb 18.

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, NSW 2750, Australia.

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http://dx.doi.org/10.1007/s00277-004-0846-yDOI Listing
May 2004

Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1 beta release from human monocytes.

J Immunol 2004 Mar;172(6):3399-405

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, New South Wales, Australia.

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http://dx.doi.org/10.4049/jimmunol.172.6.3399DOI Listing
March 2004

A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria.

J Immunol 2003 Nov;171(10):5442-6

Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW Australia.

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http://dx.doi.org/10.4049/jimmunol.171.10.5442DOI Listing
November 2003

An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor.

J Biol Chem 2003 May 13;278(19):17108-13. Epub 2003 Feb 13.

Department of Medicine, University of Sydney at Nepean Hospital, Penrith, New South Wales 2750, Australia.

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http://dx.doi.org/10.1074/jbc.M212759200DOI Listing
May 2003

Extracellular adenosine 5'-triphosphate induces a loss of CD23 from human dendritic cells via activation of P2X7 receptors.

Int Immunol 2002 Dec;14(12):1415-21

Department of Medicine, University of Sydney, Level 5 South Block, Nepean Hospital, Penrith, NSW 2750, Australia.

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http://dx.doi.org/10.1093/intimm/dxf111DOI Listing
December 2002