Publications by authors named "R G Akzhigitov"

16 Publications

[Transcranial direct current stimulation in neurology and psychiatry].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(12):123-130

Soloviev Scientific and Practical Psychoneurological Center, Moscow, Russia.

Transcranial direct current stimulation (tDCS) is a non-invasive method of modulating brain excitability by low intensity direct current. At present, there are numerous studies of tDCS application in various mental and neurological diseases. In this review, the data of tDCS efficiency in the treatment of different disorders are presented and the recommendations on using this method in clinical practice are given.
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http://dx.doi.org/10.17116/jnevro2020120121123DOI Listing
January 2021

[Prevalence of anxiety separation disorder in adult outpatients with non-psychotic mental disorders].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(6):92-98

Serbsky National Medical Research Centre for Psychiatry and Narcology, the Ministry of Health of the Russian Federation, Moscow, Russia.

Objective: To investigate the prevalence and symptoms of separation anxiety (SA) and separation anxiety disorder (SAD) in adult outpatients with non-psychotic mental disorders.

Material And Methods: Five hundred and fifty-seven outpatients over 18 years of age with nonpsychotic mental disorders were examined. Clinical, psychopathological, psychometric (the Adult Separation Anxiety Questionnaire (ASA-27), the Structured Clinical Interview for Anxiety Symptoms (SCI-SAS), the Mini-International Neuropsychiatric Interview (MINI), the Quality of Life Enjoyment and Satisfaction Questionnaire (QLES-Q) methods were used.

Results And Conclusion: SAD and SA accompany a wide range of nonpsychotic mental disorders, predominantly anxious and affective, and are highly prevalent among outpatients (24.8% and 5.4%, respectively). Patients with SAD are characterized by a high level of SA; the symptoms specific to SAD predominate in the structure of the disorder. It has been shown that during the manifestation of the disorder in childhood, the range of attachment objects widens with age, and the quality of life in such patients is lower.
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http://dx.doi.org/10.17116/jnevro202012006192DOI Listing
July 2020

[New Technologies in the Diagnostics and Treatment of Brain Deseases: from Neurosciences to the Multidisciplinary Clinical Practice and Maintaining of Mental Health].

Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med 2019 Aug;27(Special Issue):565-577

Z. P. Soloviev Research and Clinical Center for Neuropsychiatry, 115419, Moscow, Russia.

Over the past years, the prevalence of brain diseases and, consequently, their social significance and economic burden for society has been steadily increasing throughout the world. Brain diseases are a heterogeneous group of diseases that unite a number of disorders that are within the competence of both neurology and psychiatry, often concurrent or comorbid with each other. Z. P. Soloviev Research and Clinical Center for Neuropsychiatry is a leading medical organization in Moscow, which performs a full treatment cycle, studies the data and has postgraduate training programs in this field of medicine. It is conducting a number of relevant research programs; some in collaboration with international clinics. This study deals with the following programs: fundamental aspects of depression and stress-reactivity, suicidal and self-damaging behavior, usage of biofeedback and gravity therapy in rehabilitation and training programs for medical workers in successful communication.
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http://dx.doi.org/10.32687/0869-866X-2019-27-si1-565-577DOI Listing
August 2019

[Apathy in depression: a morphometric analysis].

Zh Nevrol Psikhiatr Im S S Korsakova 2019 ;119(5):141-147

Serbsky National Medical Research Centre for Psychiatry and Narcology, Moscow, Russia; Moscow Research and Clinical Center for Neuropsychiatry, Healthcare Department of Moscow, Moscow, Russia.

Aim: To study structural correlates of apathy in patients with late-life depression.

Material And Methods: Thirty-five patients (≥60 y.o.) with late-onset depression and 22 age-matched healthy volunteers underwent high resolution brain MRI-scanning, and a comprehensive neuropsychiatric examination including HAM-D and the Apathy Scale.

Results And Conclusion: A morphometric analysis showed that apathy was associated with atrophy of the lateral prefrontal cortex and reduced grey matter volume of the caudate nucleus on the right, and the nucleus accumbens on the left. Depression correlated with reduced thickness of the medial orbitofrontal cortex bilaterally, rostral anterior cingulate gyrus on the left, isthmus cingulate gyrus on the right, and larger surface area of the entorhinal cortex. Total grey matter volume, grey/white matter volumes of the cerebellum, and cortical thickness in temporal and occipital regions were negatively correlated with both apathy and depression severity. Thus, atrophy of basal ganglia and lateral prefrontal cortex, well known neuroanatomical correlates of apathy in different psychiatric and neurological conditions, characterized it in late-life depression too. This supports the idea of independent pathophysiology of apathetic syndrome.
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http://dx.doi.org/10.17116/jnevro2019119051141DOI Listing
October 2019

[Anxiety disorders in epilepsy].

Zh Nevrol Psikhiatr Im S S Korsakova 2018;118(10. Vyp. 2):37-44

Moscow Research and Clinical Center for Neuropsychiatry of the Healthcare Department, Moscow, Russia; Pirogov Russian National Research Medical University, Moscow, Russia.

This review is devoted to the place of anxiety disorders in the spectrum of psychiatric comorbidity in patients with epilepsy. The authors present general characteristics of anxiety manifestations and current views on the classification and qualification of anxiety disorders in such patients. Recent data show the relationship of anxiety with different forms of epilepsy, demographic and gender characteristics, localization of epileptic focus. The problem of bidirectional relationship of anxiety and epilepsy as well as the temporal relationship between anxiety and epileptic states are considered.
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http://dx.doi.org/10.17116/jnevro201811810237DOI Listing
May 2019
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