Publications by authors named "Quintin Pan"

53Publications

HPV33+ HNSCC is associated with poor prognosis and has unique genomic and immunologic landscapes.

Oral Oncol 2020 01 10;100:104488. Epub 2019 Dec 10.

Seidman Cancer Center, University Hospitals, Cleveland, OH 44106, United States; Department of Otolaryngology-Head and Neck Surgery, University Hospitals Cleveland Medical Center, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, United States; Case Comprehensive Cancer Center, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, United States. Electronic address:

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January 2020

Novel Peptide NIRF Optical Surgical Navigation Agents for HNSCC.

Molecules 2019 Aug 23;24(17). Epub 2019 Aug 23.

Department of Radiology, The Wright Center of Innovation in Biomedical Imaging, The Ohio State University, Columbus, OH 43210, USA.

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August 2019

Current and future management of recurrent respiratory papillomatosis.

Laryngoscope Investig Otolaryngol 2018 02 14;3(1):22-34. Epub 2018 Jan 14.

Department of Otolaryngology-Head and Neck Surgery The Ohio State University Wexner Medical Center Columbus Ohio U.S.A.

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February 2018

TriCurin, a synergistic formulation of curcumin, resveratrol, and epicatechin gallate, repolarizes tumor-associated macrophages and triggers an immune response to cause suppression of HPV+ tumors.

Cancer Immunol Immunother 2018 May 16;67(5):761-774. Epub 2018 Feb 16.

Department of Chemistry, Building 6S, The City University of New York at The College of Staten Island, 2800 Victory Boulevard, Staten Island, NY, 10314, USA.

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May 2018

Reolysin and Histone Deacetylase Inhibition in the Treatment of Head and Neck Squamous Cell Carcinoma.

Mol Ther Oncolytics 2017 Jun 10;5:87-96. Epub 2017 May 10.

Department of Otolaryngology-Head and Neck Surgery, The James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, OH 43210, USA.

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June 2017

Immunotherapy for head and neck cancer: the future of treatment?

Expert Opin Biol Ther 2017 06 11;17(6):701-708. Epub 2017 Apr 11.

b Department of Otolaryngology-Head and Neck Surgery , The Ohio State University Wexner Medical Center , Columbus , OH , USA.

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June 2017

Multiparameter Evaluation of the Heterogeneity of Circulating Tumor Cells Using Integrated RNA Hybridization and Immunocytochemical Analysis.

Front Oncol 2016 8;6:234. Epub 2016 Nov 8.

William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH, USA; Analytical Cytometry Shared Resource, Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.

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November 2016

Advancing theranostics with tumor-targeting peptides for precision otolaryngology.

World J Otorhinolaryngol Head Neck Surg 2016 Jun 26;2(2):98-108. Epub 2016 Jul 26.

Wright Center of Innovation in Biomedical Imaging, Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

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June 2016

Novel p53 therapies for head and neck cancer.

World J Otorhinolaryngol Head Neck Surg 2016 Jun 19;2(2):68-75. Epub 2016 Jul 19.

Department of Otolaryngology - Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States.

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June 2016

Image guided surgery in the management of head and neck cancer.

Oral Oncol 2016 06 25;57:32-9. Epub 2016 Apr 25.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center and Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. Electronic address:

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June 2016

Capecitabine for treating head and neck cancer.

Expert Opin Investig Drugs 2016 Jul 9;25(7):851-9. Epub 2016 May 9.

a Department of Otolaryngology - Head and Neck Surgery , The Ohio State University Wexner Medical Center and Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center , Columbus , OH , USA.

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July 2016

Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs.

Oral Oncol 2016 May 19;56:32-9. Epub 2016 Mar 19.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA; Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA; Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

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May 2016

Surgical management of oropharyngeal squamous cell carcinoma: Survival and functional outcomes.

Head Neck 2016 04 23;38 Suppl 1:E1794-802. Epub 2015 Dec 23.

Department of Otolaryngology - Head and Neck Surgery, The James Cancer Hospital and Solove Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio.

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April 2016

miR-124 Regulates the Epithelial-Restricted with Serine Box/Epidermal Growth Factor Receptor Signaling Axis in Head and Neck Squamous Cell Carcinoma.

Mol Cancer Ther 2015 Oct 30;14(10):2313-20. Epub 2015 Jul 30.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio. Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

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October 2015

ATN-224 enhances antitumor efficacy of oncolytic herpes virus against both local and metastatic head and neck squamous cell carcinoma.

Mol Ther Oncolytics 2015 20;2:15008. Epub 2015 May 20.

Department of Otolaryngology-Head and Neck Surgery, The James Cancer Hospital and Solove Research Institute, Wexner Medical Center at The Ohio State University , Columbus, Ohio, USA.

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April 2016

Are all cancer stem cells created equal?

Stem Cells Transl Med 2014 Oct 13;3(10):1111-5. Epub 2014 Aug 13.

Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center, and Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA

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October 2014

Elevated intrinsic cancer stem cell population in human papillomavirus-associated head and neck squamous cell carcinoma.

Cancer 2014 Apr 30;120(7):992-1001. Epub 2013 Dec 30.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio; Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

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April 2014

Emerging role of nanog in tumorigenesis and cancer stem cells.

Int J Cancer 2014 Dec 13;135(12):2741-8. Epub 2014 Jan 13.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH; Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, OH.

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December 2014

PKC ε Phosphorylates and Mediates the Cell Membrane Localization of RhoA.

ISRN Oncol 2013 29;2013:329063. Epub 2013 Sep 29.

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University Comprehensive Cancer Center, Columbus, OH 43210, USA ; Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

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November 2013

Genetic and chemical targeting of epithelial-restricted with serine box reduces EGF receptor and potentiates the efficacy of afatinib.

Mol Cancer Ther 2013 Aug 30;12(8):1515-25. Epub 2013 May 30.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

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August 2013

p53-based therapeutics for head and neck squamous cell carcinoma.

Oral Oncol 2013 Aug 25;49(8):733-7. Epub 2013 Apr 25.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

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August 2013

Epithelial to mesenchymal transition in head and neck squamous cell carcinoma.

Oral Oncol 2013 Apr 19;49(4):287-92. Epub 2012 Nov 19.

Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center at Ohio State University, 442 Tzagournis Medical Research, 420 West 12th Avenue, Columbus, OH 43210, USA.

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April 2013

Lipid-based nanoparticle delivery of Pre-miR-107 inhibits the tumorigenicity of head and neck squamous cell carcinoma.

Mol Ther 2012 Jun 10;20(6):1261-9. Epub 2012 Apr 10.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.

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June 2012

Synergistic enhancement of the potency and selectivity of small molecule transcriptional inhibitors.

ACS Med Chem Lett 2012 Jan;3(1):30-34

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

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January 2012

Molecular parameters of head and neck cancer metastasis.

Crit Rev Eukaryot Gene Expr 2011 ;21(2):143-53

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Medical Center, Columbus OH 43210, USA.

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March 2012

Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis.

Mol Cancer 2010 Aug 3;9:206. Epub 2010 Aug 3.

Department of Otolaryngology-Head and Neck Surgery and Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.

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August 2010

Antiangiogenic tetrathiomolybdate protects against Her2/neu-induced breast carcinoma by hypoplastic remodeling of the mammary gland.

Clin Cancer Res 2009 Dec 24;15(23):7441-6. Epub 2009 Nov 24.

Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Medical Center, Columbus, Ohio 43210, USA. Quintin.Pan

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December 2009

RhoC expression and head and neck cancer metastasis.

Mol Cancer Res 2009 Nov 27;7(11):1771-80. Epub 2009 Oct 27.

Department of Otolaryngology-Head and Neck Surgery, Ohio State University, Columbus, OH 43210, USA.

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November 2009

Inhibition of ErbB2(Her2) expression with small molecule transcription factor mimics.

Bioorg Med Chem Lett 2009 Nov 1;19(21):6233-6. Epub 2009 Sep 1.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

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November 2009

Pharmacotherapy of head and neck squamous cell carcinoma.

Expert Opin Pharmacother 2009 Oct;10(14):2291-302

The Ohio State University Medical Center, Department of Otolaryngology-Head and Neck Surgery, 456 West Tenth Avenue, Cramblett Medical Clinic, Suite 4A, Columbus, OH 43210, USA.

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October 2009

Preclinical development of a bifunctional cancer cell homing, PKCepsilon inhibitory peptide for the treatment of head and neck cancer.

Cancer Res 2009 Jul 30;69(14):5829-34. Epub 2009 Jun 30.

Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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July 2009

Protein kinase C epsilon: an oncogene and emerging tumor biomarker.

Mol Cancer 2009 Feb 19;8. Epub 2009 Feb 19.

University of Miami, Miller School of Medicine, Miami, FL 33136, USA.

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February 2009

Phase II trial of copper depletion with tetrathiomolybdate as an antiangiogenesis strategy in patients with hormone-refractory prostate cancer.

Oncology 2006 18;71(3-4):168-75. Epub 2007 Jul 18.

Department of Internal Medicine, Division of Hematology, University of Michigan School of Medicine, Ann Arbor, Mich., USA.

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August 2007

Tetrathiomolybdate promotes tumor necrosis and prevents distant metastases by suppressing angiogenesis in head and neck cancer.

Mol Cancer Ther 2007 Mar;6(3):1039-45

Department of Otolaryngology-Head and Neck Surgery, University of Michigan, 1500 East Medical Centre Drive, 1904 Taubman Center, Ann Arbor, MI 48109, USA.

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March 2007

Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma.

Cancer Res 2006 Oct;66(19):9379-84

Division of Hematology and Oncology, Department of Internal Medicine, Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, MI 48109, USA.

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October 2006

Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells.

Breast Cancer Res 2005 8;7(6):R1080-9. Epub 2005 Nov 8.

Department of Pathology, University of Michigan Medical Center, 1150 W Medical Center Drive, Ann Arbor, MI 48109, USA.

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February 2006

Protein kinase C epsilon is a predictive biomarker of aggressive breast cancer and a validated target for RNA interference anticancer therapy.

Cancer Res 2005 Sep;65(18):8366-71

Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan Health System, Ann Arbor, Michigan 48109, USA.

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September 2005

WISP3 (CCN6) is a secreted tumor-suppressor protein that modulates IGF signaling in inflammatory breast cancer.

Neoplasia 2004 Mar-Apr;6(2):179-85

Department of Pathology, Division of Hematology and Oncology, University of Michigan Medical Center, Ann Arbor, MI 48108, USA.

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November 2004

Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade.

Mol Cancer Res 2003 Aug;1(10):701-6

Department of Internal Medicine, Division of Hematology and Oncology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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August 2003

Antiangiogenic tetrathiomolybdate enhances the efficacy of doxorubicin against breast carcinoma.

Mol Cancer Ther 2003 Jul;2(7):617-22

Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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July 2003

Phase II trial of tetrathiomolybdate in patients with advanced kidney cancer.

Clin Cancer Res 2003 May;9(5):1666-72

Division of Hematology and Oncology, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor 48109-0948, USA.

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May 2003

Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.

Cancer Res 2002 Sep;62(17):4854-9

Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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September 2002

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer.

Clin Exp Metastasis 2002 ;19(4):301-11

Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, Ann Arbor 48109-0948, USA.

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July 2002

WISP3 is a novel tumor suppressor gene of inflammatory breast cancer.

Oncogene 2002 May;21(20):3172-80

Department of Pathology, University of Michigan Comprehensive Cancer Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0054, USA.

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May 2002