Publications by authors named "Quinn Lu"

29Publications

Comparative Analysis of Multiple Immunoassays for Cytokine Profiling in Drug Discovery.

SLAS Discov 2020 Dec 13;25(10):1197-1213. Epub 2020 Sep 13.

Novel Human Genetics Research Unit, GlaxoSmithKline, Collegeville, PA, USA.

View Article and Find Full Text PDF
December 2020

Strategies for controlling CRISPR/Cas9 off-target effects and biological variations in mammalian genome editing experiments.

J Biotechnol 2018 Oct 22;284:91-101. Epub 2018 Aug 22.

Target Sciences, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA. Electronic address:

View Article and Find Full Text PDF
October 2018

Applications of CRISPR genome editing technology in drug target identification and validation.

Expert Opin Drug Discov 2017 Jun 23;12(6):541-552. Epub 2017 Apr 23.

b Target Sciences, GlaxoSmithKline R&D , Stevenage , UK.

View Article and Find Full Text PDF
June 2017

A Luciferase Reporter Gene System for High-Throughput Screening of γ-Globin Gene Activators.

Methods Mol Biol 2016 ;1439:207-26

Department of Biological Sciences, Platform Technology and Science, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA, USA.

View Article and Find Full Text PDF
December 2017

Gene Expression in Mammalian Cells Using BacMam, a Modified Baculovirus System.

Methods Mol Biol 2016 ;1350:95-116

Platform Technology and Science, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, PA, 19426, USA.

View Article and Find Full Text PDF
October 2016

A High-Content Imaging Screen for Cellular Regulators of β-Catenin Protein Abundance.

J Biomol Screen 2016 Mar 9;21(3):260-8. Epub 2015 Dec 9.

R&D Platform Technology Sciences, GlaxoSmithKine, Upper Providence, Collegeville, PA, USA.

View Article and Find Full Text PDF
March 2016

Co-expression for intracellular processing in microbial protein production.

Authors:
Quinn Lu Juan C Aon

Biotechnol Lett 2014 Mar 16;36(3):427-41. Epub 2013 Oct 16.

Department of Biological Reagents & Assay Development, Platform Technology & Science, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, PA, 19426, USA,

View Article and Find Full Text PDF
March 2014

Development of a cell-based high throughput luciferase enzyme fragment complementation assay to identify nuclear-factor-e2-related transcription factor 2 activators.

Assay Drug Dev Technol 2012 Dec 10;10(6):514-24. Epub 2012 May 10.

Department of Biological Reagents and Assay Development, Platform Technology and Science, GlaxoSmithKline Pharmaceuticals, Collegeville, Pennsylvania 19426, USA.

View Article and Find Full Text PDF
December 2012

Production of protein complexes via co-expression.

Protein Expr Purif 2011 Jan 6;75(1):1-14. Epub 2010 Aug 6.

Biological Reagents & Assay Development, Platform Technology & Science, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA.

View Article and Find Full Text PDF
January 2011

Development of a high throughput cell-based assay for soluble epoxide hydrolase using BacMam technology.

Mol Biotechnol 2010 Jul;45(3):207-17

Biological Reagents and Assay Development, Molecular Discovery Research, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, PA 19426, USA.

View Article and Find Full Text PDF
July 2010

Viral-mediated gene delivery for cell-based assays in drug discovery.

Expert Opin Drug Discov 2009 Mar;4(3):243-56

Molecular Discovery Research, GlaxoSmithKline R&D, UE0433, 709 Swedeland Road, King of Prussia, PA 19406, USA +1 610 270 7602 ; +1 610 270 7359 ;

View Article and Find Full Text PDF
March 2009