Publications by authors named "Qiuming Gao"

40 Publications

Efficacy and safety of a self-developed home-based enhanced knee flexion exercise program compared with standard supervised physiotherapy to improve mobility and quality of life after total knee arthroplasty: a randomized control study.

J Orthop Surg Res 2021 Jun 14;16(1):382. Epub 2021 Jun 14.

Department of Orthopedics, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Yanchang Rd, Shanghai, 200072, People's Republic of China.

Background: This randomized controlled study compared standard supervised physiotherapy (SPT) with a self-developed, home-based, enhanced knee flexion exercise program involving a low stool (KFEH) in patients who underwent total knee arthroplasty (TKA).

Methods: Patients were recruited from July 2014 to December 2015 and randomly assigned to one of two groups: KFEH (n = 60) and SPT (n = 59). Outcomes (joint function) were evaluated according to the Knee Society Score (KSS), visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, and range of motion (ROM) assessment at selected time points (preoperatively; 1 week; 1, 3, and 6 months; and 1 year after surgery).

Results: Pain and functional improvement were observed in both groups. Non-inferiority of KFEH was evident 12 months postoperatively; however, patients in the KFEH group exhibited better ROM at 1 month (P < 0.01). Absolute WOMAC and KSS scores were slightly better in the KFEH group, although the difference was not statistically significant. There was no difference in VAS scores and complication rates between the two groups. Additionally, the home program would save patient time and decrease the economic burden associated with in-hospital SPT.

Conclusion: Considering rehabilitation and economic efficiency as well as the COVID pandemic, a home-based enhanced knee flexion exercise program for TKA rehabilitation is recommended.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13018-021-02516-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202539PMC
June 2021

Total hip arthroplasty with femoral osteotomy and modular prosthesis for proximal femoral deformity.

J Orthop Surg Res 2019 Aug 29;14(1):282. Epub 2019 Aug 29.

Department of Geriatrics Center, Xijing Hospital of Air Force Military Medical University, Xi'an, 710032, China.

Background: Severe anatomical abnormalities exist in proximal femoral deformities (PFDs). Total hip arthroplasty (THA) is associated with drawbacks such as high surgical complexity, long operation time, requirement for high surgical skills, high incidences of postoperative complications, and poor efficacy.

Objective: This study aimed to investigate the short-term efficacy of THA with femoral osteotomy and modular prosthesis implantation for femoral fixation and reconstruction in patients with PFD.

Methods: A total of 15 patients (15 hips) with rotational PFD treated with THA with femoral osteotomy and modular prosthesis between August 2012 and September 2014 were included. There were 10 male (10 hips) and 5 female (5 hips) patients. Preoperative limb shortening, intraoperative osteotomy length, and postoperative limb length were recorded. The Harris hip score was adopted for assessing the clinical results. Postoperative radiography was performed to observe the prosthesis position, as well as the presence or absence of abnormalities such as osteolysis, loosening, and subsidence of the prosthesis.

Results: All 15 patients were followed up postoperatively, with a mean follow-up duration of 62.5 (range 20-85) months. The postoperative limb-length discrepancy (1.0 ± 0.5 cm) was significantly less than the preoperative discrepancy (3.2 ± 1.2 cm) (t = - 2.501, P = 0.002). The Harris hip score significantly improved from a mean of 47.2 ± 9.9 points preoperatively to 89.7 ± 3.9 points during the last follow-up visit (t = 21.31, P = 0.001). Immediate postoperative radiographs showed restoration of limb alignment after femoral osteotomy, excellent initial press-fit fixation of the S-ROM prosthesis, and good canal filling. According to Engh's criteria, all 15 hips were graded as ingrown bones. No infection, prosthesis loosening, periprosthetic fracture, or other complications occurred.

Conclusion: In patients with femoral deformities treated with THA, precise osteotomy, good coaptation of the osteotomy surfaces, and correct choice of modular S-ROM prostheses for femoral reconstruction and fixation remain the key factors for surgical success.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13018-019-1336-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716892PMC
August 2019

A Large-Sized Reduced Graphene Oxide with Low Charge-Transfer Resistance as a High-Performance Electrode for a Nonflammable High-Temperature Stable Ionic-Liquid-Based Supercapacitor.

ChemSusChem 2018 Dec 7;11(23):4026-4032. Epub 2018 Nov 7.

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry, Beihang University, Beijing, 100191, People's Republic of China.

Large-sized reduced graphene oxide prepared was prepared by combined microwave intermittent heating and an extraction process (e.g., 900 W for 10 min (MRG-900-10)) with a lateral size of several micrometers and a thickness of 4-6 monosheets . The MRG-900-10 has a high C/O molar ratio (5.89) and a sp C content of 69.0 %, which leads to a fast electronic transmission in the sample. In addition, MRG-900-10 possesses a large specific surface area of 568.2 m  g , which increases the contact surface area between the active material and the electrolyte, thus enhancing the electron and ion transport in the interfaces when used as the electrode material in supercapacitors. MRG-900-10 possesses a low charge-transfer resistance (≈0.36 Ω). Used as the electrode material for a supercapacitor in 6 m KOH aqueous electrolyte, MRG-900-10 produces a high specific capacity of 327.6 F g at the current density of 0.5 A g . A specific capacity of 248.3 F g was obtained at a high current density of 100 A g , which indicated its high-rate ability. The initial capacity of 92 % can be maintained after 40 000 cycles at 5 A g , which indicated its high cycling stability. As for the MRG-900-10 symmetric supercapacitors, the energy densities of 11.0 and 36.2 Wh kg were obtained in 6 m KOH aqueous and 1 m tetraethylammonium tetrafluoroborate ([TEA]BF )/acetonitrile (ACN) electrolytes, respectively. Importantly, a high energy density of 68.6 Wh kg was achieved in the nonflammable ionic liquid 1-ethyl-3-methylimidazolium bis(trifluoromethane)sulfonimide ([EMIM][TFSI])/ACN (80 vol % [EMIM][TFSI]), and the supercapacitor was effective from room temperature to 100 °C.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1002/cssc.201801968DOI Listing
December 2018

Ilizarov technique for treatment of distal radius deformity and bone defect after trauma

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 10;32(10):1275-1280

Department of Orthopaedic Trauma, Lanzhou General Hospital of Lanzhou Military District, Lanzhou Gansu, 730050, P.R.China.

Objective: To investigate the effectiveness on the distal radius deformity and bone defect after trauma by using Ilizarov external fixator.

Methods: The clinical data of 9 patients of post-traumatic distal radius deformity with bone defect treated by Ilizarov technique between January 2012 and December 2016 were retrospectively analyzed. There were 7 males and 2 females with an average age of 25.6 years (range, 11-46 years). Of the 9 cases, 4 were radial baseball hand deformity with large bone defect, 4 were short deformity of distal radius, 1 was distal radius deformity with radial deflection and pronation deformity, all with distal dislocation of the distant radial-ulnar joint. The time from injury to operation was 6 months to 6.2 years (mean, 1.5 years). The bone defect was 1.4-6.8 cm (mean, 3.6 cm). After complete debridement, the forearm was fixed with Ilizarov external fixator. At 7 days after operation, bone transport or bone lengthening was performed at the rate of 0.8-1 mm/d, 4 times a day, the deformity was slowly corrected and the bone defect was repaired. According to the loss of palmar tilt angle and ulnar tilt angle measured before operation, the position of distal radial articular surface was gradually adjusted in the course of moving or prolonging, so as to restore palmar tilt angle and ulnar tilt angle as far as possible.

Results: All wounds healed by first intention and no leakage or rupture occurred. All the 9 patients were followed up 15-36 months (mean, 23 months). All the radius defects healed and the distal deformity was corrected, the healing time was 92.4-138.6 days (mean, 104.7 days); the external fixation index was 32.6-51.1 days/cm (mean, 40.2 days/cm). After 2 months of external fixator removal, the wrist joint flexion was (42.6±3.1)°, the wrist dorsum extension was (48.5±4.7)°, the palm inclination angle was (11.5±1.3)°, and the ulnar deviation angle was (21.2±3.7)°; the elbow flexion was (128.2±6.4)°, the elbow extension was (3.2±2.1)°, the forearm pronation was (71.5±4.3)°, and the forearm rotation was (38.2±6.5)°; the wrist and elbow joint extension and forearm rotation were significantly improved when compared with preoperative values ( <0.05). At last follow-up, wrist function was assessed according to Gartland-Werley standard, the results were excellent in 3 cases, good in 5 cases, and fair in 1 case. Four cases had pinhole infection, and were cured after anti inflammatory dressing change or replacement of needles; 3 cases did not heal at the bone junction, and were healed after bone grafting; 4 cases deviated from the radial force line, and the deformity was corrected after adjusting the needle.

Conclusion: Ilizarov technique can correct deformity and reconstruct bone defect of the post-traumatic distal radius simultaneously, so it is a good method to treat this kind of disease.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.7507/1002-1892.201804088DOI Listing
October 2018

Masquelet induced membrane technique for treatment of rat chronic osteomyelitis.

Exp Ther Med 2018 Oct 6;16(4):3060-3064. Epub 2018 Aug 6.

Department of Traumatic Orthopedics, Lanzhou General Hospital of CPLA, Lanzhou, Gansu 730050, P.R. China.

The application value of Masquelet induced membrane technique for the treatment of rat chronic osteomyelitis was explored. A total of 180 male Sprague-Dawley (SD) rats were randomly divided into sham operation group (control group), chronic osteomyelitis model group (model group) and Masquelet induced membrane therapy + chronic osteomyelitis model group (observation group); 60 rats in each group. A rat model of traumatic osteomyelitis was established using a modified blunt trauma method in model and observation group. All rats in observation group were treated with membrane induction technology while in the control group they were not. Postoperative complications, bone healing time and functional status of the affected limbs were recorded. After surgery, no obvious perioperative complications occurred in most of the rats, except that 5 rats experienced partial necrosis at the edge of the flap, and 3 experienced superficial infection around the incision site in the ilium. Primary bone healing was achieved in 50 rats with an average healing time of 15 weeks. Among them, 38 rats restored weight-bearing function after 20 weeks. Seven rats experienced infection after surgery, but complete bone healing was achieved after treatment with induced membrane technique again. Following treatment with induced membrane technique, the rat body weight, body temperature and the number of bacteria in the wound decreased over time. In conclusion, Masquelet induced membrane technique is effective for the treatment of large bone defects in rats after traumatic osteomyelitis. This technique significantly shortens the treatment cycle. The surgical procedure is simple, and the incidence of postoperative complications is low.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.3892/etm.2018.6573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125828PMC
October 2018

[Effectiveness of wide fascial and doubly vascularized pedicle posterior cnemis flap in repair of soft tissue defect of forefoot].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 09;32(9):1192-1195

Orthopaedic Trauma of Orthopaedic Center, Lanzhou General Hospital of Chinese PLA, Lanzhou Gansu, 730050, P.R.China.

Objective: To investigate the effectiveness of wide fascial and doubly vascularized pedicle posterior cnemis flap in repair of the soft tissue defect of forefoot.

Methods: Between March 2011 and March 2017, 18 cases with severe soft tissue defects of forefeet were repaired with the wide fascial and doubly vascularized pedicle posterior cnemis flaps. There were 13 males and 5 females with an average age of 33 years (range, 11-49 years). Of 18 cases, the defects were caused by trauma in 16 cases with an average disease duration of 15 hours (range, 3-72 hours), by infection after correction of spastic clubfoot in 1 case, and by infection after open fracture fixation in 1 case. The defects were on the planta of forefoot in 11 cases and on the dorsum of forefoot in 7 cases. The size of soft tissue defects ranged from 6 cm×4 cm to 15 cm×9 cm. All defects combined with the bone, joint, and tendon exposures and 4 defects combined with fractures. The size of flaps ranged from 8 cm×5 cm to 17 cm×10 cm. All wounds of donor sites were repaired by skin grafting.

Results: The operation time was 100-190 minutes (mean, 140 minutes). Seventeen flaps survived and wounds healed by first intention. One flap had partial necrosis and cured after dressing change. Seventeen cases were followed up 5-24 months (mean, 16 months). Both the color and texture of the flaps were satisfactory. But the pedicles of flaps were swollen. The functions of foot and ankle returned to normal.

Conclusion: The wide fascial and doubly vascularized pedicle posterior cnemis flap has reliable blood supply and sufficient venous reflux to ensure its survive, which can be used to repair severe soft tissue defect of forefoot.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.7507/1002-1892.201803111DOI Listing
September 2018

Uniform small-sized MoS from novel solution-based microwave-assisted method with exceptional reversible lithium storage properties.

Nanoscale 2018 Aug;10(32):15222-15228

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, Beijing Advanced Innovation Center for Biomedical Engineering, School of Chemistry, Beihang University, Beijing 100191, P. R. China.

Currently, MoS2 is being investigated as a lithium-ion battery (LIB) anode material because of its high theoretical capacity. However, its significantly low electrochemical activity and cyclic stability limit its utilization. Nevertheless, small-sized MoS2 possibly overcomes these issues. Herein, small-sized MoS2 with uniform particle sizes of about 20-30 nm was prepared via a novel solution-based microwave-assisted precursor pyrolysis method. The resultant MW-MoS2 sample has a high surface area of 96.9 m2 g-1 and large pore volume (0.38 cm3 g-1) with pore size distribution mainly in the meso/macropore scale, which are beneficial for electrolyte storage and low charge carrier conductive resistances. The large pore surface area and volume of the small-sized MoS2 can also ease the volume expansion during the charging and discharging process. As an LIB anode, the MW-MoS2 material exhibits an amazingly large specific capacity of 1355 mA h g-1 at a low current density of 0.5 A g-1. At a high current density of 10 A g-1, a specific capacity of 435 mA h g-1 is obtained, demonstrating its excellent rate capability. Furthermore, a large discharge capacity of 544 mA h g-1 is maintained after 500 cycles at 5 A g-1, indicating its fascinatingly high cyclic stability.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1039/c8nr02833hDOI Listing
August 2018

[Treatment of femur re-fracture with occult infection by using non-contact locking plate under deep fascia].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 01;32(1):25-30

Department of Orthopaedic Trauma, Lanzhou General Hospital of Lanzhou Military District, Lanzhou Gansu, 730050, P.R.China.

Objective: To investigate the effectiveness on the re-fracture of the femur with occult infection by using non-contact locking plate which was placed under the deep fascia.

Methods: Clinical data of 12 cases of occult infective re-fracture after femoral fracture operation were retrospectively analysed between January 2010 and December 2014. There were 8 males and 4 females with an age of 28-69 years (mean, 42.8 years). Femur re-fractured in 5 cases after 3 days to 4 weeks (mean, 10.6 days) of removal of internal fixation, including 4 cases of plate fixation and 1 case of intramedullary nail fixation; femur in 7 cases re-fractured because of breakage of internal fixator after 7-16 months (mean, 9.3 months) of internal fixation, including 5 cases of plate fixation and 2 cases of intramedullary nail fixation. The tissues near the fracture were collected for bacteria culturing and pathological examining. All the patients were treated by debriding the site of the fracture, bridging with the non-contact locking plate, and transplanting with granulated cancellous bone autograft. Intravenous infusion of antibiotics were used for 2-3 weeks after operation and oral administration for 4 weeks. The X-ray films were taken regularly and the function of the knees were evaluated by the Hospital for Special Surgery (HSS) score system.

Results: The results of bacteria culturing were positive in 8 patients and negative in 4 patients, and the pathological results of all the patients were confirmed to be chronic bone infection. All the fractures healed with no signs of exudation and ulceration of the incisions. The 12 patients were followed up 18-36 months (mean, 29.6 months). The fracture healed well and no re-fracture occurred. The fracture healing time was 14-22 weeks (mean, 18 weeks). At last follow-up, the function of the knee joint was excellent in 9 cases and good in 3 cases according to HSS score system.

Conclusion: The treatment of re-fractures after femur fracture operation needs to determine whether there is an occult infection, and non-contact locking plate placed under the deep fascia is an effective way for the re-fracture.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.7507/1002-1892.201707107DOI Listing
January 2018

Binary Hierarchical Porous Graphene/Pyrolytic Carbon Nanocomposite Matrix Loaded with Sulfur as a High-Performance Li-S Battery Cathode.

ACS Appl Mater Interfaces 2018 Jun 25;10(22):18726-18733. Epub 2018 May 25.

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, Beijing Advanced Innovation Center for Biomedical Engineering, School of Chemistry , Beihang University , Beijing 100191 , P. R. China.

A N,O-codoped hierarchical porous nanocomposite consisting of binary reduced graphene oxide and pyrolytic carbon (rGO/PC) from chitosan is fabricated. The optimized rGO/PC possesses micropores with size distribution concentrated around 1.1 nm and plenty of meso/macropores. The Brunauer-Emmett-Teller specific surface area is 480.8 m g, and it possesses impressively large pore volume of 2.14 cm g. On the basis of the synergistic effects of the following main factors: (i) the confined space effect in the hierarchical porous binary carbonaceous matrix; (ii) the anchor effects by strong chemical bonds with codoped N and O atoms; and (iii) the good flexibility and conductivity of rGO, the rGO/PC/S holding 75 wt % S exhibits high performance as Li-S battery cathode. Specific capacity of 1625 mA h g can be delivered at 0.1 C (1 C = 1675 mA g), whereas 848 mA h g can be maintained after 300 cycles at 1 C. Even at high rate of 5 C, 412 mA h g can be restrained after 1000 cycles.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsami.8b03806DOI Listing
June 2018

[Effect of exogenous L-arginie on survival of extended dorsal perforator flaps in rats].

Zhejiang Da Xue Xue Bao Yi Xue Ban 2017 May;46(6):656-661

Orthopedic Center, Lanzhou General Hospital of PLA, Lanzhou 730050, China.

Objective: To investigate the effect of exogenous L-Arg on the survival of extended perforator flap in rats. Methods: Sixteen male Sprague Dawley rats were randomly divided into L-Arg group (n=8) and control group(n=8). The extended dorsal three-vascular territory perforator flaps were made in rats. L-Arg (400 mg·kg-1·d-1) was injected intraperitoneally in L-Arg group 1d before operation, immediately and 1-7 d after operation, while the same volume of saline was injected intraperitoneally in control group at the same time points. The appearance and distribution of blood vessels were observed, and the flap survival areas were measured 7d after operation. The tissue samples were harvested from choke zone Ⅱ for histological study and the expression of vascular endothelial growth factor (VEGF) was detected by immunohistochemistry and Western blot, respectively. Results: After 7d, the clearer vascular structure and more new vessels in choke zone Ⅱ were observed in L-Arg group. The survival rate of flap in L-Arg group was (88.42±4.19)%, which was significantly higher than that in control group[(76.52±5.37)%, t=3.707, P<0.01]. The microvessel density and caliber of choke zone Ⅱ in L-Arg group was (29.47±5.28)/mm2 and(47.27±5.32)μm, which were significantly higher than those in control group (t=2.694 and 2.389, P<0.05 or P<0.01). The immunohistochemistry and Western blot showed that the expression of VEGF in choke zone Ⅱ of L-Arg group was significantly higher than that in control group (t=9.428 and -3.054,P<0.05 or P<0.01). Conclusion: Exogenous L-Arg can increase the survival rate of extended dorsal perforator skin flap through promoting vascularization and dilatation of vessels in choke zone Ⅱ in rats.
View Article and Find Full Text PDF

Download full-text PDF

Source
May 2017

Ultrahigh Oxygen Reduction Reaction Electrocatalytic Activity and Stability over Hierarchical Nanoporous N-doped Carbon.

Sci Rep 2018 02 12;8(1):2863. Epub 2018 Feb 12.

Institute of Polymer Chemistry and Physics of College of Chemistry, BNU Lab of Environmentally Friendly and Functional Polymer Materials, Beijing Normal University, Beijing, 100875, P. R. China.

Hierarchical nanoporous N-doped carbon ZNC-1000 was prepared by facile pyrolysis of well-designed nanosized ZIF-8 precursor with optimized reaction temperature and time. It possesses large surface areas leading to sufficient exposed electrochemical active sites. Meanwhile, its moderate graphitization degree and suitable nanosized hierarchical porosity distributions would lead to the sufficient interaction between O and the electrocatalyst surface which would benefit the transports of electrons and the electrolyte ions for ORR. As an electrocatalyst for oxygen reduction reaction, the ZNC-1000 presents a better catalytic property than the commercial Pt/C with 6/1 mV positive shifts for onset/half-wave potentials and 1.567 mA cm larger for limiting current density respectively. The stability of ZNC-1000 is also much better than that of Pt/C with negative shifts of 0/-2 mV (vs 5/31 mV) for onset/half-wave potentials and 6.0% vs 29.2% loss of limiting current density after 5000 cycles of accelerated durability test, as well as the relative current of 87.5% vs 40.2% retention after 30,000 s continuous chronoamperometric operation.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-21213-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809453PMC
February 2018

Upregulation of long noncoding RNA Xist promotes proliferation of osteosarcoma by epigenetic silencing of P21.

Oncotarget 2017 Nov 8;8(60):101406-101417. Epub 2017 Sep 8.

Department of Orthopedics, Shanghai Tenth People's Hospital, Tong Ji University School of Medicine, Shanghai 200072, People's Republic of China.

Recent studies show that lncRNAs involve in the initiation and progression of various cancers including osteosarcoma (OS). IncRNA Xist has been verified as an oncogene in several human cancers, and its abnormal expression was closely associated with tumor initiation and progression. Nevertheless, the role of Xist in OS remains unclear. Here, we revealed the Xist expression level was up-regulated in OS tissues and discovered that Xist knockdown significantly repressed OS cell proliferation. Additionally, mechanistic analysis revealed that Xist can repress P21 expression to regulate OS cell cycle and proliferation by binding to EZH2. Taking all into account, Xist may function in promoting OS cell proliferation and may potentially serve as a novel biomarker and therapeutic target for OS.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.20738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731884PMC
November 2017

Unusual Mesoporous Carbonaceous Matrix Loading with Sulfur as the Cathode of Lithium Sulfur Battery with Exceptionally Stable High Rate Performance.

ACS Appl Mater Interfaces 2017 Aug 17;9(34):28366-28376. Epub 2017 Aug 17.

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry, Beihang University , Beijing 100191, People's Republic of China.

Unusual three-dimensional mesoporous carbon/reduced graphene oxide (MP-C/rGO) matrix possessing graphene nanolayer pore walls built up by three to five graphene monosheets and some carbon particles with the sizes of about 5 nm located between the graphene nanolayers was prepared by facile freeze-drying and then carbonization of the poly(vinyl alcohol) and graphene oxide mixture. The mesoporous carbonaceous MP-C/rGO sample has a high specific surface area of 661.6 m g, large specific pore volume of 1.54 m g, and focused pore size distribution of 2-10 nm. About 64 wt % sulfur could be held in the pores of the MP-C/rGO matrix. As the cathode of a Li-S battery, the MP-C/rGO/S composite showed excellent electrochemical property including a high initial specific capacity of 919 mA h g at 1 C with the capacity retention ratio of 63.3% and the Coulombic efficiency above 90% after 500 cycles. Meanwhile, the initial specific capacity of 602 mA h g at 5 C and remaining capacity of 391 mA h g after 500 cycles with an outstanding Coulombic efficiency of 97% indicate its exceptionally stable rate performance.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsami.7b05825DOI Listing
August 2017

[Operative versus non-operative treatment for three- or four-part proximal humeral fractures in elderly patients: a meta-analysis of randomized controlled trials].

Zhejiang Da Xue Xue Bao Yi Xue Ban 2016 May;45(6):641-647

Orthopaedic Trauma of Orthopaedics Center, Lanzhou General Hospital of PLA, Lanzhou 730050, China.

To evaluate the efficacy of operative and non-operative treatment for three- or four-part proximal humeral fractures in elderly patients by meta-analysis. The literature search was performed in Cochrance Library, Medline, Embase, SinoMed, CNKI, Wanfang data and CQVIP databases for operative and non-operative treatment of three- or four-part proximal humeral fractures in elderly patients, and searches of conference proceedings were also conducted. The data were extracted and a meta-analysis was performed using RevMan 5.3. The outcome measures included Constants score, pain and incidence rates of AVN, reoperation, osteoarthritis, nonunion. Six randomized controlled trials involving 264 patients were included in the meta-analysis. The differences of Constant scores (=0.47, 95% :-4.35-5.28, =0.85), incidence of ANV (=0.56, 95% :0.25-1.24, =0.15), incidence of osteoarthritis (=0.56, 95% :0.19-1.68, =0.30), incidence of nonunion (=0.43, 95% :0.13-1.43, =0.17) between operative group and non-operative group were not statistically significant. Operative treatment was better in pain score (=1.01, 95% :0.12-1.19, =0.03) and had statistically significant higher reoperative rate (=3.97, 95% :1.45-10.92, =0.007). No evidence support that there is difference in Constant score and incidence rate of ANV, osteoarthritis, nonunion between operative and non-operative treatment for three- or four-part proximal humeral fractures in elderly patients. More high quality randomized controlled trials are required to determine which treatment is more efficient.
View Article and Find Full Text PDF

Download full-text PDF

Source
May 2016

[One-stage bone grafting combined with non-contact plate technique for treatment of post-traumatic femoral osteomyelitis and bone defects].

Zhejiang Da Xue Xue Bao Yi Xue Ban 2016 May;45(6):631-635

Orthopaedic Trauma of Orthopaedics Center, Lanzhou General Hospital of PLA, Lanzhou 730050, China.

Eight patients with femoral osteomyelitis were admitted in Lanzhou General Hospital of PLA between July 2012 and July 2015. During the operation the femur was fixed with non-contact locking plate after thorough debridement. Iliac morselized cancellous bones without cortical bone were filled in the bone defect after debridement. The locking plates were placed in the lateral subcutaneous interface superficial to the vastus lateralis muscle. Drainage tubes were routinely placed postoperatively. The surgery was completed successfully in all patients, and the average operation time was (130±10) min (120-150 min). Intravenous antibiotics were administrated for 2 weeks and followed by 4 week-oral antibiotics after the operation in all 8 cases. Drainage tubes remained in situ about 8 days. All patients were followed up for 12-48 months, with an average of (19±7) months. Postoperative X-ray examination showed bone union in 7 cases with an average healing time of (16±5) weeks. One patient failed with relapsed infection, and was later treated with Ilizarov apparatus after secondary debridement. No plate and screw fracture, loose and fixation failure were observed in all 8 cases.
View Article and Find Full Text PDF

Download full-text PDF

Source
May 2016

Low content Pt nanoparticles anchored on N-doped reduced graphene oxide with high and stable electrocatalytic activity for oxygen reduction reaction.

Sci Rep 2017 02 24;7:43352. Epub 2017 Feb 24.

Institute of Polymer Chemistry and Physics of College of Chemistry, BNU Lab of Environmentally Friendly and Functional Polymer Materials, Beijing Normal University, Beijing 100875, P.R. China.

A novel kind of Pt/N-rGO hybrid possessing of low content 5.31 wt.% Pt anchored on the surface of nitrogen doped reduced graphene oxide (N-rGO) evenly was prepared. The Pt has uniformed 2.8 nm diameter and exposed (111) crystal planes; meanwhile, the N works as the bridge between Pt and rGO with the Pt-N and N-C chemical bonds in Pt/N-rGO. The Pt/N-rGO material has a very high electrocatalytic activity in oxygen reduction reaction with the mass catalytic activity more than 1.5 times of the commercial Pt/C due to the synergistic catalytic effect of both N-doped carbon matrix and Pt nanoparticles. Moreover, the Pt/N-rGO exhibits an excellent stability with hardly loss (only 0.4%) after accelerated durability tests of 5000 cycles based on the stable Pt-N-C chemical bonds in Pt/N-rGO, which can prevent the detachment, dissolution, migration and aggregation of Pt nanoparticles on the matrix during the long-term cycling.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep43352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324168PMC
February 2017

Unique 1D Co3O4 crystallized nanofibers with (220) oriented facets as high-performance lithium ion battery anode material.

Sci Rep 2016 05 24;6:26460. Epub 2016 May 24.

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, Beijing 100191, P. R. China.

A novel one-step hydrothermal and calcination strategy was developed to synthesize the unique 1D oriented Co3O4 crystal nanofibers with (220) facets on the carbon matrix derived from the natural, abundant and low cost wool fibers acting as both carbon precursor and template reagent. The resultant [email protected] nanocomposite exhibited very high specific capacity and favorable high-rate capability when used as anode material of lithium ion battery. The high reversible Li(+) ion storage capacity of 986 mAh g(-1) was obtained at 100 mA g(-1) after 150 cycles, higher than the theoretical capacity of Co3O4 (890 mAh g(-1)). Even at the higher current density of 1 A g(-1), the electrode could still deliver a remarkable discharge capacity of 720 mAh g(-1) over 150 cycles.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep26460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877706PMC
May 2016

Biomass-Derived Porous Carbon with Micropores and Small Mesopores for High-Performance Lithium-Sulfur Batteries.

Chemistry 2016 Mar 2;22(10):3239-3244. Epub 2016 Feb 2.

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, Beijing, 100191, P. R. China.

Biomass-derived porous carbon BPC-700, incorporating micropores and small mesopores, was prepared through pyrolysis of banana peel followed by activation with KOH. A high specific BET surface area (2741 m  g ), large specific pore volume (1.23 cm  g ), and well-controlled pore size distribution (0.6-5.0 nm) were obtained and up to 65 wt % sulfur content could be loaded into the pores of the BPC-700 sample. When the resultant C/S composite, BPC-700-S65, was used as the cathode of a Li-S battery, a large initial discharge capacity (ca. 1200 mAh g ) was obtained, indicating a good sulfur utilization rate. An excellent discharge capacity (590 mAh g ) was also achieved for BPC-700-S65 at the high current rate of 4 C (12.72 mA cm ), showing its extremely high rate capability. A reversible capacity of about 570 mAh g was achieved for BPC-700-S65 after 500 cycles at 1 C (3.18 mA cm ), indicating an outstanding cycling stability.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.201504672DOI Listing
March 2016

One-dimensional porous nanofibers of Co3O4 on the carbon matrix from human hair with superior lithium ion storage performance.

Sci Rep 2015 Jul 23;5:12382. Epub 2015 Jul 23.

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, Beijing 100191, P. R. China.

One-dimensional (1D) hierarchical porous nanofibers of Co3O4 possessing of (220) facets on the carbon matrix from human hair ([email protected]) with 20-30 nm in width and 3-5 μm in length are prepared by a facile solvothermal and calcination approach. The well crystallized small Co3O4 particles with the diameter of about 8-12 nm were closely aggregated together in the nanofibers. Electrochemical analyses show that the first discharge capacity of [email protected] electrode is 1368 mAh g(-1) at the current density of 0.1 A g(-1) based on the total mass of composite. A high reversible capacity of 916 mAh g (-1) was obtained over 100 cycles at 0.1 A g(-1), presenting a good cycling stability. When cycled at a high current density of 1 and 2 A g(-1), the specific capacity of 659 and 573 mAh g(-1) could be still achieved, respectively, indicating a superior power capability.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep12382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511864PMC
July 2015

Preparing two-dimensional microporous carbon from Pistachio nutshell with high areal capacitance as supercapacitor materials.

Sci Rep 2014 Jul 2;4:5545. Epub 2014 Jul 2.

Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, Beijing 100191, P. R. China.

Two-dimensional (2D) porous carbon AC-SPN-3 possessing of amazing high micropore volume ratio of 83% and large surface area of about 1069 m(2) g(-1) is high-yield obtained by pyrolysis of natural waste Pistachio nutshells with KOH activation. The AC-SPN-3 has a curved 2D lamellar morphology with the thickness of each slice about 200 nm. The porous carbon is consists of highly interconnected uniform pores with the median pore diameter of about 0.76 nm, which could potentially improve the performance by maximizing the electrode surface area accessible to the typical electrolyte ions (such as TEA(+), diameter = ~0.68 nm). Electrochemical analyses show that AC-SPN-3 has significantly large areal capacitance of 29.3/20.1 μF cm(-2) and high energy density of 10/39 Wh kg(-1) at power of 52/286 kW kg(-1) in 6 M KOH aqueous electrolyte and 1 M TEABF4 in EC-DEC (1:1) organic electrolyte system, respectively.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep05545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078435PMC
July 2014

[DESIGN AND APPLICATION OF ANTEROLATERAL THIGH FREE FLAP WITH OBLIQUE BRANCH].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2014 Jul;28(7):865-8

Objective: To investigate the feasibility of the anterolateral thigh free flap with the oblique branch in reconstructing the soft tissue defects of lower extremity.

Methods: Between June 2009 and February 2013, 12 patients (including 7 males and 5 females) with soft tissue defects of lower extremity were treated with the anterolateral thigh free flap with the oblique branch, aged from 8 to 42 years (median, 32 years). The locations of soft tissue defect were the dorsum of the foot in 5 cases, the ankle and foot in 4 cases, the lower leg in 2 cases, and the distal foot in 1 case. All defects were associated with exposure of tendon and bone. The size of the wound was from 15 cm x 7 cm to 27 cm x 12 cm. The interval of injury and operation was 1 to 7 days (mean, 3.7 days). The anterolateral thigh flap was pedicled with only the oblique branch in 7 patients, and with the both descending branch and oblique branch in 5 patients, and the size of flap was from 17 cm x 9 cm to 30 cm x 15 cm. The donor sites were repaired by suture in 3 patients, and by skin graft in 9 patients.

Results: Distal skin flap necrosis occurred in 1 case, and was cured after dressing change and skin graft. The other flaps survived, and the donor site healed primarily. The follow-up time was from 10 months to 2 years (mean, 18 months). Thinning operation was performed in 3 cases, and the other flaps recovered pain and warm sensation with good appearance.

Conclusion: It is a safe and effective method to reconstruct soft tissue defects of the lower extremity with the anterolateral thigh flap pedicled with the oblique branch.
View Article and Find Full Text PDF

Download full-text PDF

Source
July 2014

Constructing free standing metal organic framework MIL-53 membrane based on anodized aluminum oxide precursor.

Sci Rep 2014 May 13;4:4947. Epub 2014 May 13.

1] Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, Beijing 100191, P. R. China [2] Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.

Metal organic framework (MOF) materials have attracted great attention due to their well-ordered and controllable pores possessing of prominent potentials for gas molecule sorption and separation performances. Organizing the MOF crystals to a continuous membrane with a certain scale will better exhibit their prominent potentials. Reports in recent years concentrate on well grown MOF membranes on specific substrates. Free standing MOF membranes could have more important applications since they are independent from the substrates. However, the method to prepare such a membrane has been a great challenge because good mechanical properties and stabilities are highly required. Here, we demonstrate a novel and facile technique for preparing the free standing membrane with a size as large as centimeter scale. The substrate we use proved itself not only a good skeleton but also an excellent precursor to fulfill the reaction. This kind of membrane owns a strong mechanical strength, based on the fact that it is much thinner than the composite membranes grown on substrates and it could exhibit good property of gas separation.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep04947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018608PMC
May 2014

Facile approach to prepare nickel cobaltite nanowire materials for supercapacitors.

Small 2011 Sep 11;7(17):2454-9. Epub 2011 Jul 11.

State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road Shanghai 200050, P.R. China.

Excellent electrochemical performance results from the coexistence of nickel and cobalt ions, with mesoporous characteristics and nanocrystal structure. Nickel cobalt nanowire is prepared by hydrothermal and thermal decomposition processes. High capacitance of 722 F g(-1) can be obtained at 1 A g(-1) in 6 M KOH, with a capacitance retention ratio of ca. 79% at 20 A g(-1) .
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1002/smll.201100534DOI Listing
September 2011

Enhanced hydrogen storage capacity of nanosized copper loaded active carbons treated under CO2.

J Nanosci Nanotechnol 2010 Nov;10(11):7648-53

The State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Graduate School, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.

A kind of composites with nanosized Cu loaded on activated active carbons was prepared. The materials were characterized by X-ray diffraction (XRD) patterns, transmission electron microscope (TEM) and nitrogen adsorption. The highest surface area of 2746 m2/g was obtained for the optimized activated active carbon. TEM image and size distribution analyses show that the ball-like Cu(0) particles are dispersed homogeneously in the composites with diameters of 10-30 nm. The electrochemical hydrogen storage properties were determined and an optimized discharge capacity of 605.5 mAh/g was gotten, which corresponds to 2.24 wt% of hydrogen uptake capacity.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1166/jnn.2010.2766DOI Listing
November 2010

Fe-substituted titanate nanosheets intercalated with hemoglobin for direct electrochemistry.

Biosens Bioelectron 2009 Dec 1;25(4):948-51. Epub 2009 Sep 1.

Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, People's Repblic of China.

Fe-substituted titania nanosheets (FTNS) are used as support matrixes for hemoglobin (Hb) immobilization and protein electrode fabrication to study the direct electron transfer between the redox centers of proteins and the electrode. X-ray diffraction (XRD) and high-resolution transmission electron microscope (HRTEM) reveal that the Hb-FTNS composite has an ordered layered structure with a monolayer arrangement in the interlayers. The native structure of the intercalated Hb is maintained, as indicated by the ultraviolet-visible (UV-vis) and Fourier-transform infrared (FTIR) spectroscopy. The Hb-FTNS modified electrode shows a fast direct electron transfer for the Hb Fe(III)/Fe(II) redox couple and exhibits good electrocatalytic properties for the reduction of H(2)O(2). The sensitivity of Hb-FTNS modified electrode for the reduction of H(2)O(2) is 156mAM(-1)cm(-2) in the linear range of 2-65 microM, which is 18 times higher than that of Hb-titania nanosheets modified electrode (8.54mAM(-1)cm(-2)), suggesting that the Fe doping maybe an efficient method to improve the electrochemical performance of TNS for biosensors, biofuel cells and bioelectronics applications.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bios.2009.08.040DOI Listing
December 2009

Immobilization of hemoglobin at the galleries of layered lepidocrocite-related potassium lithium titanate.

J Nanosci Nanotechnol 2009 Feb;9(2):1615-8

State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Graduate School, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China.

The exfoliated nanosheets from the layered potassium lithium titanate K0.8Ti1.73Li0.27O4 can be assembled with the hemoglobin through the electrostatic attraction under mild conditions. The immobilized enzyme has regularly layered structure based on the small angel X-ray diffraction. The preparation method is low cost and the maximum bounding capacity of enzyme is large. The enzyme activity study showed that the immobilized Hb retained enzyme-like peroxidase activity, and the activity increased along with the increase of the interlayer distances. Michaelis-Menten model methods were used to study the peroxidase activity.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1166/jnn.2009.c215DOI Listing
February 2009

In-situ Fourier transform infrared spectroscopy study on CO oxidation over Au/titanate and Au/titania nanocatalysts.

J Nanosci Nanotechnol 2009 Feb;9(2):1483-6

State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Graduate School, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, People's Republic of China.

Surface charge state and surface hydroxyl coverage of the catalyst support were reported to have great impact on the CO catalytic oxidation activity. Protonic layered titanate nanotubes are featured with cation-vacancy defects and full surface Ti-OH group coverage, whereas titania nanoparticles are featured with anion-vacancy defects and partly Ti-OH surface group coverage. In order to explore the influence on the activity from these differences, Fourier transform infrared spectra study of CO adsorption and oxidation over the Au/titanate and Au/titania catalysts is performed and the results indicate that (i) both Au/titanate and Au/titania have strong adsorption for CO molecules, and (ii) the Au/titania sample has a higher reactive activity for CO oxidation than the Au/titanate sample. This phenomenon is reasonably explained combining with a traditional strong metal-support interaction theory known in CO catalytic oxidation reactions.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1166/jnn.2009.c184DOI Listing
February 2009

High hydrogen storage capacity of porous carbons prepared by using activated carbon.

J Am Chem Soc 2009 May;131(20):7016-22

State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Graduate School, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050, People's Republic of China.

A kind of activated carbon with further carbon dioxide and potassium hydroxide activations for hydrogen storage was investigated. The carbon dioxide and potassium hydroxide activations have apparently different effects on the pore structures and textures of the activated carbon which closely associated with the hydrogen storage properties. The potassium hydroxide activation can remarkably donate microporosity to the frameworks of the activated carbon. One of the resultant porous carbons exhibited a high surface area of up to 3190 m(2) g(-1) and large gravimetric hydrogen uptake capacity of 7.08 wt % at 77 K and 20 bar, which is one of the largest data reported for the porous carbon materials. This result suggests that the porous carbon with large amounts of active sites, high surface area, and high micropore volume related to optimum pore size could achieve high gravimetric hydrogen storage.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1021/ja8083225DOI Listing
May 2009

A novel nanoscale catalyst system composed of nanosized Pd catalysts immobilized on Fe(3)O(4)@SiO(2)-PAMAM.

Nanotechnology 2008 Feb 31;19(7):075714. Epub 2008 Jan 31.

State Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050, People's Republic of China.

This study reports the syntheses of Fe(3)O(4)@SiO(2)-Gn-PAMAM-Pd(0) composites and their applications as magnetically recoverable catalysts for the hydrogenation of allyl alcohol. The controlled growth of polyamidoamine (PAMAM) dendrimers with different generations on Fe(3)O(4)@SiO(2) surfaces was monitored by FT-IR spectra. Subsequently, Pd nanoparticles with diameters of about 2.5 nm were stabilized homogeneously on the surface of Fe(3)O(4)@SiO(2)-Gn-PAMAM (n = 1-4), investigated by thermogravimetry (TG) and transmission electron microscopy (TEM) measurements. The Fe(3)O(4)@SiO(2)-Gn-PAMAM-Pd(0) have high catalytic activity for the hydrogenation of allyl alcohol and the rate of the reaction can be controlled by changing the generation of PAMAM. In particular, the composites made of superparamagnetic Fe(3)O(4) nanocrystals with diameters of about 10 nm are very suitable as catalyst supports for catalyst separation under a relatively low external magnetic field and catalyst re-dispersion after removing the external magnetic field.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1088/0957-4484/19/7/075714DOI Listing
February 2008

Hemoglobin niobate composite based biosensor for efficient determination of hydrogen peroxide in a broad pH range.

Authors:
Lu Gao Qiuming Gao

Biosens Bioelectron 2007 Feb 2;22(7):1454-60. Epub 2006 Aug 2.

State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Graduate School, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Rd., Shanghai 200050, PR China.

Inorganic layered niobates (HCa2Nb3O10) were used as immobilization matrices of hemoglobin (Hb) because of their tunable interlayer spaces, large surface areas and good biocompatibilities. A pair of well-defined, quasi-reversible cycle voltammertric peaks were obtained at the Hb-HCa2Nb3O10 modified pyrolytic graphite electrode, suggesting that the layered niobates facilitate the electron transfer between the proteins and the electrode. Hb-HCa2Nb3O10 modified electrode exhibited electrocatalytic response for monitoring H2O2 with a large linear detection range from 25 microM to 3.0 mM and a relatively high sensitivity of 172 microA mM-1 cm-2. Based on the stabilizing effect of the layered niobates, Hb-HCa2Nb3O10 modified electrode can detect H2O2 in strongly acidic and basic solutions with pH of 1-12, which greatly expands the application fields of biosensors.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bios.2006.06.022DOI Listing
February 2007
-->