Publications by authors named "Qinghe Xing"

100Publications

Mutations disrupting neuritogenesis genes confer risk for cerebral palsy.

Nat Genet 2020 Oct 28;52(10):1046-1056. Epub 2020 Sep 28.

Pediatric Movement Disorders Program, Division of Pediatric Neurology, Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, AZ, USA.

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http://dx.doi.org/10.1038/s41588-020-0695-1DOI Listing
October 2020

Long non-coding RNA ESCCAL-1 promotes esophageal squamous cell carcinoma by down regulating the negative regulator of APOBEC3G.

Cancer Lett 2020 Nov 6;493:217-227. Epub 2020 Sep 6.

Translational Medical Center, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, 450007, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2020.09.001DOI Listing
November 2020

Risk and Association of HLA Alleles with Methimazole-Induced Cutaneous Adverse Reactions in Chinese Han Population.

J Invest Dermatol 2020 Jul 1. Epub 2020 Jul 1.

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2020.05.117DOI Listing
July 2020

HLA-A*02:01 allele is associated with tanshinone-induced cutaneous drug reactions in Chinese population.

Pharmacogenomics J 2020 06 3;20(3):408-414. Epub 2019 Dec 3.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Mingdao building, 131 Dong-an Rd., Xuihui District, Shanghai, China.

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http://dx.doi.org/10.1038/s41397-019-0121-1DOI Listing
June 2020

Autophagy-Related Gene 7 Polymorphisms and Cerebral Palsy in Chinese Infants.

Front Cell Neurosci 2019 5;13:494. Epub 2019 Nov 5.

Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

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http://dx.doi.org/10.3389/fncel.2019.00494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848160PMC
November 2019

Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis.

Biol Proced Online 2019 15;21:20. Epub 2019 Oct 15.

1Renji Hospital, Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200032 China.

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http://dx.doi.org/10.1186/s12575-019-0108-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794783PMC
October 2019

Role of microRNA-145 in protection against myocardial ischemia/reperfusion injury in mice by regulating expression of GZMK with the treatment of sevoflurane.

J Cell Physiol 2019 Mar 14. Epub 2019 Mar 14.

Institutes of Biomedical Sciences, Fudan University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.1002/jcp.28323DOI Listing
March 2019

De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.

Authors:
Katherine L Helbig Robert J Lauerer Jacqueline C Bahr Ivana A Souza Candace T Myers Betül Uysal Niklas Schwarz Maria A Gandini Sun Huang Boris Keren Cyril Mignot Alexandra Afenjar Thierry Billette de Villemeur Delphine Héron Caroline Nava Stéphanie Valence Julien Buratti Christina R Fagerberg Kristina P Soerensen Maria Kibaek Erik-Jan Kamsteeg David A Koolen Boudewijn Gunning H Jurgen Schelhaas Michael C Kruer Jordana Fox Somayeh Bakhtiari Randa Jarrar Sergio Padilla-Lopez Kristin Lindstrom Sheng Chih Jin Xue Zeng Kaya Bilguvar Antigone Papavasileiou Qinghe Xing Changlian Zhu Katja Boysen Filippo Vairo Brendan C Lanpher Eric W Klee Jan-Mendelt Tillema Eric T Payne Margot A Cousin Teresa M Kruisselbrink Myra J Wick Joshua Baker Eric Haan Nicholas Smith Azita Sadeghpour Erica E Davis Nicholas Katsanis Mark A Corbett Alastair H MacLennan Jozef Gecz Saskia Biskup Eva Goldmann Lance H Rodan Elizabeth Kichula Eric Segal Kelly E Jackson Alexander Asamoah David Dimmock Julie McCarrier Lorenzo D Botto Francis Filloux Tatiana Tvrdik Gregory D Cascino Sherry Klingerman Catherine Neumann Raymond Wang Jessie C Jacobsen Melinda A Nolan Russell G Snell Klaus Lehnert Lynette G Sadleir Britt-Marie Anderlid Malin Kvarnung Renzo Guerrini Michael J Friez Michael J Lyons Jennifer Leonhard Gabriel Kringlen Kari Casas Christelle M El Achkar Lacey A Smith Alexander Rotenberg Annapurna Poduri Alba Sanchis-Juan Keren J Carss Julia Rankin Adam Zeman F Lucy Raymond Moira Blyth Bronwyn Kerr Karla Ruiz Jill Urquhart Imelda Hughes Siddharth Banka Ulrike B S Hedrich Ingrid E Scheffer Ingo Helbig Gerald W Zamponi Holger Lerche Heather C Mefford

Am J Hum Genet 2019 Mar;104(3):562

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http://dx.doi.org/10.1016/j.ajhg.2019.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407522PMC
March 2019

De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias.

Authors:
Katherine L Helbig Robert J Lauerer Jacqueline C Bahr Ivana A Souza Candace T Myers Betül Uysal Niklas Schwarz Maria A Gandini Sun Huang Boris Keren Cyril Mignot Alexandra Afenjar Thierry Billette de Villemeur Delphine Héron Caroline Nava Stéphanie Valence Julien Buratti Christina R Fagerberg Kristina P Soerensen Maria Kibaek Erik-Jan Kamsteeg David A Koolen Boudewijn Gunning H Jurgen Schelhaas Michael C Kruer Jordana Fox Somayeh Bakhtiari Randa Jarrar Sergio Padilla-Lopez Kristin Lindstrom Sheng Chih Jin Xue Zeng Kaya Bilguvar Antigone Papavasileiou Qinghe Xing Changlian Zhu Katja Boysen Filippo Vairo Brendan C Lanpher Eric W Klee Jan-Mendelt Tillema Eric T Payne Margot A Cousin Teresa M Kruisselbrink Myra J Wick Joshua Baker Eric Haan Nicholas Smith Azita Sadeghpour Erica E Davis Nicholas Katsanis Mark A Corbett Alastair H MacLennan Jozef Gecz Saskia Biskup Eva Goldmann Lance H Rodan Elizabeth Kichula Eric Segal Kelly E Jackson Alexander Asamoah David Dimmock Julie McCarrier Lorenzo D Botto Francis Filloux Tatiana Tvrdik Gregory D Cascino Sherry Klingerman Catherine Neumann Raymond Wang Jessie C Jacobsen Melinda A Nolan Russell G Snell Klaus Lehnert Lynette G Sadleir Britt-Marie Anderlid Malin Kvarnung Renzo Guerrini Michael J Friez Michael J Lyons Jennifer Leonhard Gabriel Kringlen Kari Casas Christelle M El Achkar Lacey A Smith Alexander Rotenberg Annapurna Poduri Alba Sanchis-Juan Keren J Carss Julia Rankin Adam Zeman F Lucy Raymond Moira Blyth Bronwyn Kerr Karla Ruiz Jill Urquhart Imelda Hughes Siddharth Banka Ulrike B S Hedrich Ingrid E Scheffer Ingo Helbig Gerald W Zamponi Holger Lerche Heather C Mefford

Am J Hum Genet 2018 11 18;103(5):666-678. Epub 2018 Oct 18.

Division of Genetic Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183031
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http://dx.doi.org/10.1016/j.ajhg.2018.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216110PMC
November 2018

HLA-C*12:02 is strongly associated with Xuesaitong-induced cutaneous adverse drug reactions.

Pharmacogenomics J 2019 06 20;19(3):277-285. Epub 2018 Sep 20.

Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

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http://dx.doi.org/10.1038/s41397-018-0051-3DOI Listing
June 2019

Variants of the OLIG2 Gene are Associated with Cerebral Palsy in Chinese Han Infants with Hypoxic-Ischemic Encephalopathy.

Neuromolecular Med 2019 03 3;21(1):75-84. Epub 2018 Sep 3.

Institute of Biomedical Science and Children's Hospital, Fudan University, Shanghai, 201102, China.

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http://dx.doi.org/10.1007/s12017-018-8510-1DOI Listing
March 2019

Association of NOS1 gene polymorphisms with cerebral palsy in a Han Chinese population: a case-control study.

BMC Med Genomics 2018 Jun 25;11(1):56. Epub 2018 Jun 25.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Wanyuan Road 399, Minhang District, Shanghai, 201102, China.

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http://dx.doi.org/10.1186/s12920-018-0374-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019815PMC
June 2018

Combined Analysis of Gene Polymorphisms and Protein Expression in Children With Cerebral Palsy.

Front Neurol 2018 22;9:182. Epub 2018 Mar 22.

Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

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http://dx.doi.org/10.3389/fneur.2018.00182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874289PMC
March 2018

A Variant of the Autophagy-Related 5 Gene Is Associated with Child Cerebral Palsy.

Front Cell Neurosci 2017 18;11:407. Epub 2017 Dec 18.

Institute of Biomedical Science and Children's Hospital, and Key Laboratory of Reproduction Regulation of the National Population and Family Planning Commission (NPFPC), Shanghai Institute of Planned Parenthood Research (SIPPR), IRD, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3389/fncel.2017.00407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741640PMC
December 2017

The DNA methylation status of genes encoding Matrix metalloproteinases and tissue inhibitors of Matrix metalloproteinases in endometriosis.

Mol Reprod Dev 2018 01 21;85(1):17-25. Epub 2017 Dec 21.

Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1002/mrd.22931DOI Listing
January 2018

Clinical, Viral and Genetic Characteristics of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) in Shanghai, China.

Acta Derm Venereol 2018 Apr;98(4):401-405

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.

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http://dx.doi.org/10.2340/00015555-2867DOI Listing
April 2018

Dynamic Editome of Zebrafish under Aminoglycosides Treatment and Its Potential Involvement in Ototoxicity.

Front Pharmacol 2017 22;8:854. Epub 2017 Nov 22.

Institutes of Biomedical Sciences and Children's Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.3389/fphar.2017.00854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702851PMC
November 2017

SPRINT: an SNP-free toolkit for identifying RNA editing sites.

Bioinformatics 2017 Nov;33(22):3538-3548

State Key Laboratory of Genetic Engineering and Collaborative Innovation Center for Genetics and Development.

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http://dx.doi.org/10.1093/bioinformatics/btx473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870768PMC
November 2017

p53 regulates ERK1/2/CREB cascade via a novel SASH1/MAP2K2 crosstalk to induce hyperpigmentation.

J Cell Mol Med 2017 10 6;21(10):2465-2480. Epub 2017 Apr 6.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1111/jcmm.13168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618682PMC
October 2017

Detection of Turner syndrome using X-chromosome inactivation specific differentially methylated CpG sites: A pilot study.

Clin Chim Acta 2017 May 8;468:174-179. Epub 2017 Mar 8.

Children Hospital of Fudan University, Shanghai, China; Shanghai Key Laboratory of Prevention and Intervention of Birth Defects, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2017.03.008DOI Listing
May 2017

HLA-A*02 alleles are associated with tetanus antitoxin-induced exanthematous drug eruptions in Chinese patients.

Pharmacogenet Genomics 2016 Dec;26(12):538-546

aInstitutes of Biomedical Sciences bDepartment of Dermatology, Huashan Hospital cChildren's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai dDepartment of Pharmacology, School of Medicine, Zhengzhou University, Zhengzhou, China.

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http://dx.doi.org/10.1097/FPC.0000000000000248DOI Listing
December 2016

A FBN1 mutation association with different phenotypes of Marfan syndrome in a Chinese family.

Clin Chim Acta 2016 Sep 25;460:102-6. Epub 2016 Jun 25.

Department of Cardiology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2016.06.031DOI Listing
September 2016

Regulation of cytochrome P450 3A4 by small vault RNAb derived from the non-coding vault RNA1 of multidrug resistance-linked vault particle.

Mol Med Rep 2016 Jul 9;14(1):387-93. Epub 2016 May 9.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China.

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http://dx.doi.org/10.3892/mmr.2016.5228DOI Listing
July 2016

Association Between Osteopontin Gene Polymorphisms and Cerebral Palsy in a Chinese Population.

Neuromolecular Med 2016 Jun 25;18(2):232-8. Epub 2016 Apr 25.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai, 200032, People's Republic of China.

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http://dx.doi.org/10.1007/s12017-016-8397-7DOI Listing
June 2016

Mutations in TUBB8 and Human Oocyte Meiotic Arrest.

N Engl J Med 2016 Jan;374(3):223-32

From the State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, MOE Key Laboratory of Contemporary Anthropology, and Collaborative Innovation Center of Genetics and Development, School of Life Sciences, Fudan University (R.F., Q.S., Y.X., R.Q., X.W., H.W., Q.L., Q.X., L.J., L.H., L.W.), Shanghai Ji Ai Genetics and IVF Institute, Obstetrics and Gynecology Hospital, Fudan University (X.S., M.Y., J.C.), Department of Otolaryngology, Eye and ENT Hospital, Fudan University (L.G.), Department of Integrative Medicine and Neurobiology, State Key Laboratory of Medical Neurobiology, and Shanghai Medical College, Fudan University (Y.F.), the Reproductive Medicine Center, Shanghai Ninth Hospital, Shanghai Jiao Tong University (Y.K., Z.Y., S.Z., B.L.), Shanghai Institute of Planned Parenthood Research (Z.S., M.L., H.S.), and Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University (L.H.), Shanghai, Reproductive Medicine Center, Shaanxi Maternal and Child Care Service Center, Shaanxi (J.S.), and Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing (R.C.) - all in China; the Department of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York (G.T., N.J.C.); the Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago (A.L., Y. Fukuda, M.L.G.); the Department of Physiology-Endocrinology, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden (R.S.); the Department of Genetics, Development and Cell Biology, Iowa State University, Ames (M.L.G.); and the Life Sciences Division, Lawrence Berkeley National Laboratory (R.Z., E.N.), the Molecular and Cell Biology Department (E.N.), and the Howard Hughes Medical Institute (E.N.), University of California Berkeley, Berkeley.

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http://dx.doi.org/10.1056/NEJMoa1510791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767273PMC
January 2016

HLADR: a database system for enhancing the discovery of biomarkers for predicting human leukocyte antigen-mediated idiosyncratic adverse drug reactions.

Biomark Med 2015 26;9(11):1079-93. Epub 2015 Oct 26.

Center for Pharmacogenomics & State Key Laboratory of Genetic Engineering, School of Life Sciences & School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China.

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http://dx.doi.org/10.2217/bmm.15.98DOI Listing
August 2016

Hsa-miR-27a is involved in the regulation of CYP3A4 expression in human livers from Chinese Han population.

Pharmacogenomics 2015 31;16(12):1379-86. Epub 2015 Jul 31.

Shanghai Genome Pilot Institutes for Genomics & Human Health, Shanghai 200030, PR China.

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http://dx.doi.org/10.2217/pgs.15.82DOI Listing
June 2016

Loci with genome-wide associations with schizophrenia in the Han Chinese population.

Br J Psychiatry 2015 Dec 23;207(6):490-4. Epub 2015 Jul 23.

Zhiqiang Li, PhD, Children's Hospital, Fudan University, Shanghai and Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai; Yuqian Xiang, PhD, Children's Hospital, Fudan University, Shanghai; Jianhua Chen, PhD, Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai; Qiaoli Li, PhD, Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai; Jiawei Shen, PhD, Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai; Yun Liu, PhD, Institutes of Biomedical Sciences, Fudan University, Shanghai; Wenjin Li, PhD, Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai; Qinghe Xing, PhD, Institutes of Biomedical Sciences, Fudan University, Shanghai; Qingzhong Wang, PhD, Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai; Lei Wang, PhD, Institutes of Biomedical Sciences, Fudan University, Shanghai; Guoyin Feng, Shanghai Institute of Mental Health, Shanghai; Lin He, PhD, Children's Hospital, Fudan University, Shanghai and Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai; Xinzhi Zhao, PhD, Children's Hospital, Fudan University, Shanghai; Yongyong Shi, PhD, Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, People's Republic of China

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http://dx.doi.org/10.1192/bjp.bp.114.150490DOI Listing
December 2015

Experimental validation of candidate schizophrenia gene CALN1 as a target for microRNA-137.

Neurosci Lett 2015 Aug 7;602:110-4. Epub 2015 Jul 7.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043940153002
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http://dx.doi.org/10.1016/j.neulet.2015.07.001DOI Listing
August 2015

Research on Susceptible Genes and Immunological Pathogenesis of Cutaneous Adverse Drug Reactions in Chinese Hans.

J Investig Dermatol Symp Proc 2015 Jul;17(1):29-31

Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1038/jidsymp.2015.6DOI Listing
July 2015

Prenatal nutritional deficiency reprogrammed postnatal gene expression in mammal brains: implications for schizophrenia.

Int J Neuropsychopharmacol 2014 Oct 31;18(4). Epub 2014 Oct 31.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai, China (Drs Xu, Zhou, T. Wang, Xiang, Xing, Liu, L. Wang, Li, L. He and X. Zhao); Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China (Drs Xu, G. He, Zhou, T. Wang, Xiang, Q. Zhao, Xing, Liu, L.Wang, Li, L. He and X. Zhao); Center for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Shanghai, China (Dr Xu); Cancer Epigenetics and Gene Therapy Program, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, China (Dr Zhu); Department of Mental Health, University of Aberdeen, Scotland (Dr St Clair).

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http://dx.doi.org/10.1093/ijnp/pyu054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360220PMC
October 2014

Association of dopamine receptor D1 (DRD1) polymorphisms with risperidone treatment response in Chinese schizophrenia patients.

Neurosci Lett 2015 Jan 29;584:178-83. Epub 2014 Aug 29.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, People's Republic of China; Shanghai Genomepilot Institutes, Shanghai, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2014.08.041DOI Listing
January 2015

DNA methylome profiling of maternal peripheral blood and placentas reveal potential fetal DNA markers for non-invasive prenatal testing.

Mol Hum Reprod 2014 Sep 4;20(9):875-84. Epub 2014 Jul 4.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China

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https://academic.oup.com/molehr/article-lookup/doi/10.1093/m
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http://dx.doi.org/10.1093/molehr/gau048DOI Listing
September 2014

Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42.

Hum Mol Genet 2014 Dec 2;23(23):6201-11. Epub 2014 Jul 2.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200032, PR China, Institutes of Biomedical Sciences, Fudan University, No 138 Yixueyuan Road, Shanghai 200032, PR China,

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http://dx.doi.org/10.1093/hmg/ddu340DOI Listing
December 2014

The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy.

J Neuroinflammation 2014 Jun 6;11:100. Epub 2014 Jun 6.

Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, 7 Kangfu Street, 450052 Zhengzhou, China.

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http://dx.doi.org/10.1186/1742-2094-11-100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060844PMC
June 2014

Association between ε2/3/4, promoter polymorphism (-491A/T, -427T/C, and -219T/G) at the apolipoprotein E gene, and mental retardation in children from an iodine deficiency area, China.

Biomed Res Int 2014 25;2014:236702. Epub 2014 Mar 25.

Bio-X Institute, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, China ; Institute for Neuropsychiatric Science and Metabonomics, Changning Mental Health Center, Shanghai 200335, China ; Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of Chinese Academy Sciences, Shanghai 200031, China.

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http://www.hindawi.com/journals/bmri/2014/236702/
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http://dx.doi.org/10.1155/2014/236702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984859PMC
January 2015

The association of apolipoprotein E gene polymorphisms with cerebral palsy in Chinese infants.

Mol Genet Genomics 2014 Jun 13;289(3):411-6. Epub 2014 Feb 13.

Department of Pediatrics, the Third Affiliated Hospital of Zhengzhou University, Kangfuqian Street 7, Zhengzhou, 450052, People's Republic of China.

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http://dx.doi.org/10.1007/s00438-014-0818-4DOI Listing
June 2014

Quantitative methylation level of the EPHX1 promoter in peripheral blood DNA is associated with polycystic ovary syndrome.

PLoS One 2014 5;9(2):e88013. Epub 2014 Feb 5.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China ; Institutes of Biomedical Science, Fudan University, Shanghai, China ; Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088013PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914883PMC
November 2014

A pharmacogenetic study of risperidone on chemokine (C-C motif) ligand 2 (CCL2) in Chinese Han schizophrenia patients.

Prog Neuropsychopharmacol Biol Psychiatry 2014 Jun 2;51:153-8. Epub 2014 Feb 2.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2014.01.017DOI Listing
June 2014

Promoter methylation assay of SASH1 gene in breast cancer.

J BUON 2013 Oct-Dec;18(4):891-8

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai.

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March 2014

A possible new mechanism in the pathophysiology of polycystic ovary syndrome (PCOS): the discovery that leukocyte telomere length is strongly associated with PCOS.

J Clin Endocrinol Metab 2014 Feb 3;99(2):E234-40. Epub 2013 Dec 3.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology (Q.L., R.F., Y.X., H.W., Q.S., L.J., L.W.), School of Life Sciences, Fudan University, Shanghai, 200032, China; Institutes of Biomedical Sciences (Q.L., R.F., Y.X., H.W., Q.S., Q.X., X.Z., L.H., L.W.), Fudan University, Shanghai, 200032, China; Bio-X Center (L.H.), Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, 200032, China; and NPFPC Laboratory of Contraception and Devices, Shanghai Institute of Planned Parenthood Research (J.D.), Shanghai 200032, China.

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http://dx.doi.org/10.1210/jc.2013-3685DOI Listing
February 2014

The association between GAD1 gene polymorphisms and cerebral palsy in Chinese infants.

Tsitol Genet 2013 Sep-Oct;47(5):22-7

Children's Hospital of Fudan University, Shanghai, China.

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December 2013

Genetic association study of adaptor protein complex 4 with cerebral palsy in a Han Chinese population.

Mol Biol Rep 2013 Nov 25;40(11):6459-67. Epub 2013 Sep 25.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, 130 Dongan Road, Shanghai, 200032, China,

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http://dx.doi.org/10.1007/s11033-013-2761-6DOI Listing
November 2013

Identification of microRNAs in human follicular fluid: characterization of microRNAs that govern steroidogenesis in vitro and are associated with polycystic ovary syndrome in vivo.

J Clin Endocrinol Metab 2013 Jul 10;98(7):3068-79. Epub 2013 May 10.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1210/jc.2013-1715DOI Listing
July 2013

Pharmacogenomics can improve antipsychotic treatment in schizophrenia.

Front Med 2013 Jun 21;7(2):180-90. Epub 2013 Apr 21.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1007/s11684-013-0249-3DOI Listing
June 2013

Histamine H4 receptor polymorphism: a potential predictor of risperidone efficacy.

J Clin Psychopharmacol 2013 Apr;33(2):221-5

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, PR China.

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http://dx.doi.org/10.1097/JCP.0b013e318283963bDOI Listing
April 2013

Association of Interleukin 6 gene polymorphisms with genetic susceptibilities to spastic tetraplegia in males: a case-control study.

Cytokine 2013 Mar 13;61(3):826-30. Epub 2013 Feb 13.

Children's Hospital and Institute of Biomedical Science, Fudan University, Shanghai 201102, China.

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http://dx.doi.org/10.1016/j.cyto.2013.01.011DOI Listing
March 2013

Identification and functional study of a new missense mutation in the motor head domain of myosin VIIA in a family with autosomal dominant hearing impairment (DFNA11).

PLoS One 2013 29;8(1):e55178. Epub 2013 Jan 29.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055178PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558421PMC
July 2013

SASH1 regulates melanocyte transepithelial migration through a novel Gαs-SASH1-IQGAP1-E-Cadherin dependent pathway.

Cell Signal 2013 Jun 16;25(6):1526-38. Epub 2013 Jan 16.

Child Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1016/j.cellsig.2012.12.025DOI Listing
June 2013

Common genetic variation in CYP1B1 is associated with concentrations of T₄, FT₃ and FT₄ in the sera of polycystic ovary syndrome patients.

Mol Biol Rep 2013 Apr 3;40(4):3315-20. Epub 2013 Jan 3.

Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.

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http://link.springer.com/10.1007/s11033-012-2406-1
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http://dx.doi.org/10.1007/s11033-012-2406-1DOI Listing
April 2013

Quantitative analysis of follistatin (FST) promoter methylation in peripheral blood of patients with polycystic ovary syndrome.

Reprod Biomed Online 2013 Feb 23;26(2):157-63. Epub 2012 Oct 23.

State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.rbmo.2012.10.011DOI Listing
February 2013

Promoter hypomethylation of TIMP3 is associated with pre-eclampsia in a Chinese population.

Mol Hum Reprod 2013 Mar 19;19(3):153-9. Epub 2012 Nov 19.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai, China.

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http://dx.doi.org/10.1093/molehr/gas054DOI Listing
March 2013

The role of the TOB1 gene in growth suppression of hepatocellular carcinoma.

Oncol Lett 2012 Nov 16;4(5):981-987. Epub 2012 Aug 16.

Institutes of Biomedical Sciences and Children's Hospital, Fudan University, Shanghai 200032; ; School of Life Sciences, Nantong University, Nantong 226019, P.R. China.

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http://dx.doi.org/10.3892/ol.2012.864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499594PMC
November 2012

Effects of SASH1 on melanoma cell proliferation and apoptosis in vitro.

Mol Med Rep 2012 Dec 26;6(6):1243-8. Epub 2012 Sep 26.

Children's Hospital, Institute of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China.

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http://dx.doi.org/10.3892/mmr.2012.1099DOI Listing
December 2012

Dynamic network of transcription and pathway crosstalk to reveal molecular mechanism of MGd-treated human lung cancer cells.

PLoS One 2012 31;7(5):e31984. Epub 2012 May 31.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031984PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365074PMC
October 2012

Lack of support for association between the copy number variants in the FCGR locus and schizophrenia: a case control study.

Neurosci Lett 2012 Aug 1;522(2):85-91. Epub 2012 May 1.

Children's Hospital and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China.

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http://dx.doi.org/10.1016/j.neulet.2012.04.037DOI Listing
August 2012

Analysis of JAG1 gene variant in Chinese patients with Alagille syndrome.

Gene 2012 May 2;499(1):191-3. Epub 2012 Mar 2.

Children's Hospital of Fudan University, Shanghai, China; Institute of Biomedical Sciences, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.gene.2012.02.038DOI Listing
May 2012

Association of leukocyte telomere length with type 2 diabetes in mainland Chinese populations.

J Clin Endocrinol Metab 2012 Apr 8;97(4):1371-4. Epub 2012 Feb 8.

Institutes of Biomedical Sciences, Fudan University, Shanghai, 303 Mingdao Building, 138 Yixueyuan Road, Shanghai 200032, People's Republic of China.

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http://dx.doi.org/10.1210/jc.2011-1562DOI Listing
April 2012

Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action.

J Proteome Res 2011 Dec 8;10(12):5433-43. Epub 2011 Nov 8.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, China.

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http://dx.doi.org/10.1021/pr2006796DOI Listing
December 2011

A pharmacogenetic study of risperidone on histamine H3 receptor gene (HRH3) in Chinese Han schizophrenia patients.

J Psychopharmacol 2012 Jun 7;26(6):813-8. Epub 2011 Jun 7.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1177/0269881111405358DOI Listing
June 2012

A novel mutation of the PTCH1 gene activates the Shh/Gli signaling pathway in a Chinese family with nevoid basal cell carcinoma syndrome.

Biochem Biophys Res Commun 2011 Jun 13;409(2):166-70. Epub 2011 Apr 13.

Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1100621
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http://dx.doi.org/10.1016/j.bbrc.2011.04.047DOI Listing
June 2011

Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population.

J Lipid Res 2011 Feb 12;52(2):354-60. Epub 2010 Dec 12.

Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China.

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http://dx.doi.org/10.1194/jlr.P007476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023556PMC
February 2011

A systematic genetic polymorphism analysis of the CYP2C9 gene in four different geographical Han populations in mainland China.

Genomics 2011 May 29;97(5):277-81. Epub 2010 Nov 29.

Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, China.

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http://dx.doi.org/10.1016/j.ygeno.2010.11.004DOI Listing
May 2011

Promoter hypomethylation of COMT in human placenta is not associated with the development of pre-eclampsia.

Mol Hum Reprod 2011 Mar 3;17(3):199-206. Epub 2010 Nov 3.

Institute of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.

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https://academic.oup.com/molehr/article-lookup/doi/10.1093/m
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http://dx.doi.org/10.1093/molehr/gaq092DOI Listing
March 2011

Methylenetetrahydrofolate reductase gene polymorphisms and cerebral palsy in Chinese infants.

J Hum Genet 2011 Jan 21;56(1):17-21. Epub 2010 Oct 21.

Department of Pediatrics, Children's Hospital of Fudan University, Shanghai, PR China.

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http://dx.doi.org/10.1038/jhg.2010.127DOI Listing
January 2011

Pharacogenetic effects of dopamine transporter gene polymorphisms on response to chlorpromazine and clozapine and on extrapyramidal syndrome in schizophrenia.

Prog Neuropsychopharmacol Biol Psychiatry 2010 Aug 24;34(6):1026-32. Epub 2010 May 24.

Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders Ministry of Education, Shanghai Jiao Tong University, Shanghai 200030, PR China.

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http://dx.doi.org/10.1016/j.pnpbp.2010.05.017DOI Listing
August 2010

Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China.

Genomics 2010 Apr 25;95(4):224-9. Epub 2010 Jan 25.

Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1016/j.ygeno.2010.01.005DOI Listing
April 2010

A case-control association study between the CYP3A4 and CYP3A5 genes and schizophrenia in the Chinese Han population.

Prog Neuropsychopharmacol Biol Psychiatry 2009 Oct 8;33(7):1200-4. Epub 2009 Jul 8.

Bio-X Center, Shanghai JiaoTong University, Shanghai 200030, China.

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http://dx.doi.org/10.1016/j.pnpbp.2009.06.023DOI Listing
October 2009

SePreSA: a server for the prediction of populations susceptible to serious adverse drug reactions implementing the methodology of a chemical-protein interactome.

Nucleic Acids Res 2009 Jul 5;37(Web Server issue):W406-12. Epub 2009 May 5.

Bio-X Center, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, PR China.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkp312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703957PMC
July 2009

Association analysis of serotonin receptor 7 gene (HTR7) and risperidone response in Chinese schizophrenia patients.

Prog Neuropsychopharmacol Biol Psychiatry 2009 Apr 20;33(3):547-51. Epub 2009 Feb 20.

Bio-X Center, Shanghai Jiao Tong University, Shanghai 200030, PR China.

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http://linkinghub.elsevier.com/retrieve/pii/S027858460900050
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http://dx.doi.org/10.1016/j.pnpbp.2009.02.008DOI Listing
April 2009

Systematic polymorphism analysis of the CYP2D6 gene in four different geographical Han populations in mainland China.

Genomics 2008 Sep 15;92(3):152-8. Epub 2008 Jul 15.

Bio-X Life Science Research Center, Shanghai Jiao Tong University, Hao Ran Building, Shanghai 200030, China.

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http://dx.doi.org/10.1016/j.ygeno.2008.05.004DOI Listing
September 2008

Genetic polymorphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China.

Pharmacogenomics 2008 Jun;9(6):691-702

Bio-X Life Science Research Center, Shanghai Jiao Tong University, Hao Ran Building, Shanghai 200030, China.

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http://dx.doi.org/10.2217/14622416.9.6.691DOI Listing
June 2008

Dopamine transporter polymorphisms and risperidone response in Chinese schizophrenia patients: an association study.

Pharmacogenomics 2007 Oct;8(10):1337-45

Shanghai Jiao Tong University, Bio-X Center, Haoran Building, 1954 Huashan Road, Shanghai 200030, China.

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http://dx.doi.org/10.2217/14622416.8.10.1337DOI Listing
October 2007

Effects of the dopamine D3 receptor (DRD3) gene polymorphisms on risperidone response: a pharmacogenetic study.

Neuropsychopharmacology 2008 Jan 11;33(2):305-11. Epub 2007 Apr 11.

Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1038/sj.npp.1301418DOI Listing
January 2008

Systematic screening for polymorphisms in the CYP3A4 gene in the Chinese population.

Pharmacogenomics 2006 Sep;7(6):831-41

Bio-X Center, Shanghai JiaoTong University, 1954 Huashan Road, Shanghai 200030, China.

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http://dx.doi.org/10.2217/14622416.7.6.831DOI Listing
September 2006

A novel mutation of PAX3 in a Chinese family with Waardenburg syndrome.

Mol Vis 2006 Aug 28;12:1001-8. Epub 2006 Aug 28.

Bio-X Center, Shanghai Jiao Tong University, Shanghai, China.

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August 2006