Publications by authors named "Qingguo Xu"

43Publications

Association between donor/recipient MTRR gene polymorphisms and the risk of new-onset neurological complications after liver transplantation.

J Neuroimmunol 2020 Nov 7;350:577438. Epub 2020 Nov 7.

The Affiliated Hospital of Qingdao University, Qingdao, CN 266003, China. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2020.577438DOI Listing
November 2020

Neutrophil Extracellular Traps Increase Airway Mucus Viscoelasticity and Slow Mucus Particle Transit.

Am J Respir Cell Mol Biol 2020 Oct 23. Epub 2020 Oct 23.

Virginia Commonwealth University, 6889, Department of Pharmaceutics, Richmond, Virginia, United States.

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http://dx.doi.org/10.1165/rcmb.2020-0168OCDOI Listing
October 2020

3D engineering for optic neuropathy treatment.

Drug Discov Today 2020 Oct 7. Epub 2020 Oct 7.

Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA 23298, USA; Ophthalmology, Center for Pharmaceutical Engineering, Massey Cancer Center, and Institute for Structural Biology, Drug Discovery & Development (ISB3D), Virginia Commonwealth University, Richmond, VA 23298, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2020.09.034DOI Listing
October 2020

Sunitinib malate-loaded biodegradable microspheres for the prevention of corneal neovascularization in rats.

J Control Release 2020 Nov 18;327:456-466. Epub 2020 Aug 18.

Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Departments of Pharmaceutics, Virginia Commonwealth University, Richmond, VA 23298, USA; Department of Ophthalmology, Massey Cancer Center, Center for Pharmaceutical Engineering, Institute for Structural Biology, Drug Discovery & Development, Virginia Commonwealth University, Richmond, VA 23298, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2020.08.019DOI Listing
November 2020

Dry powder aerosol containing muco-inert particles for excipient enhanced growth pulmonary drug delivery.

Nanomedicine 2020 10 3;29:102262. Epub 2020 Jul 3.

Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA, USA; Department of Ophthalmology, Massey Cancer Center, Center for Pharmaceutical Engineering, and Institute for Structural Biology, Drug Discovery & Development (ISB3D), Virginia Commonwealth University, Richmond, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2020.102262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508849PMC
October 2020

Evaluation of co-delivery of colistin and ciprofloxacin in liposomes using an in vitro human lung epithelial cell model.

Int J Pharm 2019 Oct 12;569:118616. Epub 2019 Aug 12.

Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2019.118616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739157PMC
October 2019

Presence of Posterior Staphyloma in Congenital Cataract Children.

Curr Eye Res 2019 12 5;44(12):1319-1324. Epub 2019 Jul 5.

Department of Ophthalmology, Eye Institute of Eye and Ear, Nose, and Throat Hospital of Fudan University, Shanghai, China.

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http://dx.doi.org/10.1080/02713683.2019.1637437DOI Listing
December 2019

Therapeutic implications of nanomedicine for ocular drug delivery.

Drug Discov Today 2019 08 15;24(8):1524-1538. Epub 2019 May 15.

Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA; Center for Pharmaceutical Engineering and Sciences, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA; Department of Ophthalmology, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA; Massey Cancer Center, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2019.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717514PMC
August 2019

Fenofibrate-Loaded Biodegradable Nanoparticles for the Treatment of Experimental Diabetic Retinopathy and Neovascular Age-Related Macular Degeneration.

Mol Pharm 2019 05 26;16(5):1958-1970. Epub 2019 Mar 26.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center , Sun Yat-sen University , Guangzhou , Guangdong 510060 , China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b01319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502649PMC
May 2019

Upregulated KPNA2 promotes hepatocellular carcinoma progression and indicates prognostic significance across human cancer types.

Acta Biochim Biophys Sin (Shanghai) 2019 Mar;51(3):285-292

Third Department of Hepatic Surgery, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, China.

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http://dx.doi.org/10.1093/abbs/gmz003DOI Listing
March 2019

Controlled release of dexamethasone sodium phosphate with biodegradable nanoparticles for preventing experimental corneal neovascularization.

Nanomedicine 2019 04 21;17:119-123. Epub 2019 Jan 21.

Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Center for Nanomedicine, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA, USA; Department of Ophthalmology, and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520116PMC
April 2019

Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis.

J Control Release 2019 02 17;296:68-80. Epub 2019 Jan 17.

Department of Ophthalmology, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Center for Nanomedicine, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21231, USA; Departments of Oncology, Neurosurgery, and Pharmacology & Molecular Sciences, The Johns Hopkins University, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2019.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476551PMC
February 2019

Spatial Patterns and Drivers of Microbial Taxa in a Karst Broadleaf Forest.

Front Microbiol 2018 26;9:1691. Epub 2018 Jul 26.

Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China.

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https://www.frontiersin.org/article/10.3389/fmicb.2018.01691
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http://dx.doi.org/10.3389/fmicb.2018.01691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070632PMC
July 2018

Differential physiological and metabolic response to low temperature in two zoysiagrass genotypes native to high and low latitude.

PLoS One 2018 11;13(6):e0198885. Epub 2018 Jun 11.

Department of Pratacultural Sciences, College of Agronomy, Hunan Agricultural University, Changsha, Hunan, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198885PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995380PMC
January 2019

Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility.

Eur J Pharm Sci 2018 Jun 21;118:124-133. Epub 2018 Mar 21.

Buchanan Ocular Therapeutics Unit, Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09280987183013
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http://dx.doi.org/10.1016/j.ejps.2018.03.023DOI Listing
June 2018

Ti self-doped mesoporous black TiO/graphene assemblies for unpredicted-high solar-driven photocatalytic hydrogen evolution.

J Colloid Interface Sci 2017 Nov 30;505:1031-1038. Epub 2017 Jun 30.

Department of Epidemiology and Biostatistics, Harbin Medical University, Harbin 150086, People's Republic of China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219797173076
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http://dx.doi.org/10.1016/j.jcis.2017.06.097DOI Listing
November 2017

Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina.

Proc Natl Acad Sci U S A 2017 05 17;114(18):E3719-E3728. Epub 2017 Apr 17.

Wilmer Eye Institute; Johns Hopkins School of Medicine, Baltimore, MD 21231;

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http://dx.doi.org/10.1073/pnas.1617721114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422825PMC
May 2017

Development of Absorbable, Antibiotic-Eluting Sutures for Ophthalmic Surgery.

Transl Vis Sci Technol 2017 Jan 3;6(1). Epub 2017 Jan 3.

Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1167/tvst.6.1.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225995PMC
January 2017

GRAIN INCOMPLETE FILLING 2 regulates grain filling and starch synthesis during rice caryopsis development.

J Integr Plant Biol 2017 Feb;59(2):134-153

State Key Laboratory of Rice Biology, Key Laboratory of Rice Biology and Breeding of Ministry of Agriculture, China National Rice Research Institute, Hangzhou 310006, China.

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http://dx.doi.org/10.1111/jipb.12510DOI Listing
February 2017

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.

Proc Natl Acad Sci U S A 2016 09 24;113(36):E5328-36. Epub 2016 Aug 24.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

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http://dx.doi.org/10.1073/pnas.1611406113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018752PMC
September 2016

The Prediction of Clinical Outcome in Hepatocellular Carcinoma Based on a Six-Gene Metastasis Signature.

Clin Cancer Res 2017 Jan 22;23(1):289-297. Epub 2016 Jul 22.

The Third Department of Hepatic Surgery, Eastern Hepatobiliary Hospital, Second Military Medical University, Shanghai, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0395DOI Listing
January 2017

Nanoparticles coated with high molecular weight PEG penetrate mucus and provide uniform vaginal and colorectal distribution in vivo.

Nanomedicine (Lond) 2016 06 12;11(11):1337-43. Epub 2016 May 12.

Center for Nanomedicine, Johns Hopkins University School of Medicine, 400 N. Broadway, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.2217/nnm-2016-0047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897967PMC
June 2016

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery.

Adv Drug Deliv Rev 2016 Apr 9;99(Pt A):28-51. Epub 2015 Oct 9.

The Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2015.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798869PMC
April 2016

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo.

ACS Nano 2015 Sep 31;9(9):9217-27. Epub 2015 Aug 31.

Department of Ophthalmology, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine , Baltimore, Maryland 21231, United States.

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http://pubs.acs.org/doi/10.1021/acsnano.5b03876
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http://dx.doi.org/10.1021/acsnano.5b03876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890729PMC
September 2015

Exogenous glycinebetaine alleviates the detrimental effect of Cd stress on perennial ryegrass.

Ecotoxicology 2015 Aug 2;24(6):1330-40. Epub 2015 Jul 2.

College of Agriculture, Hunan Agricultural University, Changsha, 410128, Hunan, People's Republic of China.

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http://dx.doi.org/10.1007/s10646-015-1508-7DOI Listing
August 2015

Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats.

J Control Release 2015 Mar 8;201:32-40. Epub 2015 Jan 8.

Department of Ophthalmology, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Center for Nanomedicine, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037178PMC
March 2015

Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides.

Macromol Biosci 2015 Jan 4;15(1):52-62. Epub 2014 Dec 4.

Department of Bioengineering, University of Utah, 36 S. Wasatch Drive, 3100 SMBB, Salt Lake City, Utah, 84112, USA.

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http://dx.doi.org/10.1002/mabi.201400436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430332PMC
January 2015

Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI).

Nanomedicine 2015 Feb 15;11(2):401-5. Epub 2014 Nov 15.

Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15499634140055
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http://dx.doi.org/10.1016/j.nano.2014.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330119PMC
February 2015

Brain-penetrating nanoparticles improve paclitaxel efficacy in malignant glioma following local administration.

ACS Nano 2014 Oct 8;8(10):10655-64. Epub 2014 Oct 8.

Center for Nanomedicine at the Wilmer Eye Institute, ‡Department of Biomedical Engineering, ∥Department of Ophthalmology, #Deparments of Oncology, Pharmacology and Molecular Sciences, and Neurosurgery, Johns Hopkins University School of Medicine , Baltimore, Maryland 21231, United States.

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http://dx.doi.org/10.1021/nn504210gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212792PMC
October 2014

High correlation between thermotolerance and photosystem II activity in tall fescue.

Photosynth Res 2014 Dec 22;122(3):305-14. Epub 2014 Aug 22.

Key Laboratory of Plant Germplasm Enhancement and Speciality Agriculture, Wuhan Botanical Garden,, Chinese Academy of Science, Wuhan City, 430074, Hubei, People's Republic of China,

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http://dx.doi.org/10.1007/s11120-014-0035-3DOI Listing
December 2014

Characterization of a biodegradable coralline hydroxyapatite/calcium carbonate composite and its clinical implementation.

Biomed Mater 2013 Dec 28;8(6):065007. Epub 2013 Nov 28.

Department of Orthopaedic Surgery, Affiliated Hospital, Hainan Medical College, #33 Longhua Road, Haikou, Hainan Province, People's Republic of China.

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http://dx.doi.org/10.1088/1748-6041/8/6/065007DOI Listing
December 2013

Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus.

J Control Release 2013 Sep 7;170(2):279-86. Epub 2013 Jun 7.

The Center for Nanomedicine, The Johns Hopkins University School of Medicine, 400 N. Broadway, Baltimore 21231, USA.

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http://dx.doi.org/10.1016/j.jconrel.2013.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730524PMC
September 2013

Nanotechnology approaches for ocular drug delivery.

Middle East Afr J Ophthalmol 2013 Jan-Mar;20(1):26-37

Department of Ophthalmology, Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.4103/0974-9233.106384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617524PMC
January 2014

Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo.

J Control Release 2013 Apr 28;167(1):76-84. Epub 2013 Jan 28.

Department of Ophthalmology, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/j.jconrel.2013.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693951PMC
April 2013

Systematic assessment of microneedle injection into the mouse cornea.

Eur J Med Res 2012 Jun 20;17:19. Epub 2012 Jun 20.

The Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1186/2047-783X-17-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478193PMC
June 2012

Prolonged osteogenesis from human mesenchymal stem cells implanted in immunodeficient mice by using coralline hydroxyapatite incorporating rhBMP2 microspheres.

J Biomed Mater Res A 2010 Mar;92(4):1256-64

Botnar Research Centre, Institute of Musculoskeletal Sciences, Nuffield Department of Orthopaedic Surgery, University of Oxford, Oxford, UK.

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http://doi.wiley.com/10.1002/jbm.a.32453
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http://dx.doi.org/10.1002/jbm.a.32453DOI Listing
March 2010

Preparation and characterization of negatively charged poly(lactic-co-glycolic acid) microspheres.

J Pharm Sci 2009 Jul;98(7):2377-89

Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH, UK.

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http://dx.doi.org/10.1002/jps.21612DOI Listing
July 2009

Controlled release of amoxicillin from hydroxyapatite-coated poly(lactic-co-glycolic acid) microspheres.

J Control Release 2008 Apr 11;127(2):146-53. Epub 2008 Feb 11.

Department of Materials, University of Oxford, Parks Road, Oxford, OX1 3PH, United Kingdom.

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http://dx.doi.org/10.1016/j.jconrel.2008.01.017DOI Listing
April 2008

Encapsulation and release of a hydrophobic drug from hydroxyapatite coated liposomes.

Biomaterials 2007 Jun 16;28(16):2687-94. Epub 2007 Feb 16.

Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH, UK.

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http://dx.doi.org/10.1016/j.biomaterials.2007.02.007DOI Listing
June 2007