Qimin Zhan

Qimin Zhan

UNVERIFIED PROFILE

Are you Qimin Zhan?   Register this Author

Register author
Qimin Zhan

Qimin Zhan

Publications by authors named "Qimin Zhan"

Are you Qimin Zhan?   Register this Author

100Publications

3096Reads

17Profile Views

Antitumor Effect of Periplocin in TRAIL-Resistant gastric cancer cells via upregulation of death receptor through activating ERK1/2-EGR1 pathway.

Mol Carcinog 2019 Jun 1;58(6):1033-1045. Epub 2019 Mar 1.

Research Centre, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, China.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/mc.22991
Publisher Site
http://dx.doi.org/10.1002/mc.22991DOI Listing
June 2019

Corrigendum to "A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma" [EBioMedicine 41 (2019) 244-255].

EBioMedicine 2019 05 14;43:650. Epub 2019 May 14.

Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing 100142, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558293PMC
May 2019

The diacylglycerol kinase α (DGKα)/Akt/NF-κB feedforward loop promotes esophageal squamous cell carcinoma (ESCC) progression via FAK-dependent and FAK-independent manner.

Oncogene 2019 04 7;38(14):2533-2550. Epub 2018 Dec 7.

Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, 100142, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-018-0604-6DOI Listing
April 2019

Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation.

Mol Oncol 2019 04 1;13(4):959-977. Epub 2019 Mar 1.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/1878-0261.12466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441895PMC
April 2019

Regulation of OLC1 protein expression by the anaphase-promoting complex.

Oncol Lett 2019 Mar 2;17(3):2639-2646. Epub 2019 Jan 2.

State Key Laboratory of Molecular Oncology, Chinese Academy of Medical Sciences and Peking Union Medical College, Cancer Institute and Cancer Hospital, Beijing 100021, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ol.2019.9881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366124PMC
March 2019

A PLK1 kinase inhibitor enhances the chemosensitivity of cisplatin by inducing pyroptosis in oesophageal squamous cell carcinoma.

EBioMedicine 2019 Mar 12;41:244-255. Epub 2019 Mar 12.

Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing 100142, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2019.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442225PMC
March 2019

Molecular predictors of brain metastasis-related microRNAs in lung adenocarcinoma.

PLoS Genet 2019 02 1;15(2):e1007888. Epub 2019 Feb 1.

Department of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1007888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374053PMC
February 2019

Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer.

Theranostics 2019 20;9(5):1401-1416. Epub 2019 Feb 20.

State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://www.thno.org/v09p1401.htm
Publisher Site
http://dx.doi.org/10.7150/thno.30701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401504PMC
February 2019

Development of a metabolic pathway-based pseudo-targeted metabolomics method using liquid chromatography coupled with mass spectrometry.

Talanta 2019 Jan 11;192:160-168. Epub 2018 Sep 11.

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China; Centre for Bioimaging & Systems Biology, Minzu University of China, Beijing 100081, PR China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00399140183093
Publisher Site
http://dx.doi.org/10.1016/j.talanta.2018.09.021DOI Listing
January 2019

Flotillin1 promotes EMT of human small cell lung cancer via TGF-β signaling pathway.

Cancer Biol Med 2018 Nov;15(4):400-414

State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://www.cancerbiomed.org/index.php/cocr/article/view/1300
Publisher Site
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372910PMC
November 2018

Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan.

EMBO Rep 2018 10 20;19(10). Epub 2018 Aug 20.

Key Laboratory of Regenerative Medicine of Ministry of Education, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201745494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172461PMC
October 2018

MiR-423-5p in brain metastasis: potential role in diagnostics and molecular biology.

Cell Death Dis 2018 09 17;9(10):936. Epub 2018 Sep 17.

Department of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41419-018-0955-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141540PMC
September 2018

Cdk phosphorylation licenses Kif4A chromosome localization required for early mitotic progression.

J Mol Cell Biol 2018 08;10(4):358-370

State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jmcb/mjy033DOI Listing
August 2018

Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma.

BMC Cell Biol 2018 08 20;19(1):16. Epub 2018 Aug 20.

State Key Laboratory of Molecular Oncology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Cancer Center/Cancer Hospital, Beijing, 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12860-018-0167-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102840PMC
August 2018

The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment.

Mol Cancer 2018 08 21;17(1):125. Epub 2018 Aug 21.

Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12943-018-0871-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103855PMC
August 2018

Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.

Biomed Pharmacother 2018 Jun 24;102:502-509. Epub 2018 Mar 24.

Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, NO. 52, Beijing 100142, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biopha.2018.03.106DOI Listing
June 2018

Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation.

J Genet Genomics 2017 12 16;44(12):557-565. Epub 2017 Oct 16.

State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jgg.2017.09.008DOI Listing
December 2017

Downregulation of β-arrestin 1 suppresses glioblastoma cell malignant progression vis inhibition of Src signaling.

Exp Cell Res 2017 08 22;357(1):51-58. Epub 2017 Apr 22.

Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00144827173025
Publisher Site
http://dx.doi.org/10.1016/j.yexcr.2017.04.023DOI Listing
August 2017

Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.

Epigenetics 2017 07 5;12(7):575-583. Epub 2017 Jul 5.

a Department of Gastroenterology & Hepatology , Chinese PLA General Hospital , Beijing , China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15592294.2017.1341027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687330PMC
July 2017

Downregulation of miR-503 Promotes ESCC Cell Proliferation, Migration, and Invasion by Targeting Cyclin D1.

Genomics Proteomics Bioinformatics 2017 06 9;15(3):208-217. Epub 2017 Jun 9.

State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gpb.2017.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487524PMC
June 2017

Long noncoding RNA HULC modulates the phosphorylation of YB-1 through serving as a scaffold of extracellular signal-regulated kinase and YB-1 to enhance hepatocarcinogenesis.

Hepatology 2017 05 22;65(5):1612-1627. Epub 2017 Mar 22.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.29010DOI Listing
May 2017

Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations.

Nat Commun 2017 05 26;8:15290. Epub 2017 May 26.

Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms15290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477513PMC
May 2017

Autoreactive T Cells and Chronic Fungal Infection Drive Esophageal Carcinogenesis.

Cell Host Microbe 2017 Apr;21(4):478-493.e7

Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chom.2017.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868740PMC
April 2017

The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells.

Oncotarget 2017 Feb;8(8):13240-13252

Key Laboratory of Molecular and Cellular Systems Biology, Tianjin Normal University, Tianjin 300387, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.14658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355092PMC
February 2017

miR-503-3p promotes epithelial-mesenchymal transition in breast cancer by directly targeting SMAD2 and E-cadherin.

J Genet Genomics 2017 02 1;44(2):75-84. Epub 2016 Nov 1.

State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jgg.2016.10.005DOI Listing
February 2017

Corrigendum to "KDM4C, a H3K9me3 histone demethylase, is involved in the maintenance of human ESCC-initiating cells by epigenetically enhancing SOX2 expression" [Neoplasia 18 (2016) 594-609].

Neoplasia 2016 12;18(12):810

Henan Key Laboratory of Cancer Epigenetics, Cancer Institute, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neo.2016.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156518PMC
December 2016

Kindlin-2 interacts with β-catenin and YB-1 to enhance EGFR transcription during glioma progression.

Oncotarget 2016 Nov;7(46):74872-74885

State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/12439
Publisher Site
http://dx.doi.org/10.18632/oncotarget.12439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342708PMC
November 2016

Silencing NKD2 by Promoter Region Hypermethylation Promotes Esophageal Cancer Progression by Activating Wnt Signaling.

J Thorac Oncol 2016 11 30;11(11):1912-1926. Epub 2016 Jun 30.

Department of Gastroenterology and Hepatology, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtho.2016.06.015DOI Listing
November 2016

GADD45A inhibits autophagy by regulating the interaction between BECN1 and PIK3C3.

Autophagy 2015 ;11(12):2247-58

a State Key Laboratory of Molecular Oncology; Cancer Institute and Hospital; Chinese Academy of Medical Sciences & Peking Union Medical College ; Beijing , China.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/15548627.2015.1
Publisher Site
http://dx.doi.org/10.1080/15548627.2015.1112484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835191PMC
October 2016

Global metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and staging.

Sci Rep 2016 10 11;6:35010. Epub 2016 Oct 11.

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100050, P. R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep35010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057114PMC
October 2016

KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression.

Neoplasia 2016 10 19;18(10):594-609. Epub 2016 Sep 19.

Henan Key Laboratory of Cancer Epigenetics, Cancer Institute, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neo.2016.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035342PMC
October 2016

Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling.

Oncotarget 2016 Aug;7(34):55555-55571

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.10864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342436PMC
August 2016

MicroRNA-548j functions as a metastasis promoter in human breast cancer by targeting Tensin1.

Mol Oncol 2016 06 23;10(6):838-49. Epub 2016 Feb 23.

State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Collaborative Innovation Center for Cancer Medicine, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molonc.2016.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423174PMC
June 2016

Bioinformatic exploration of MTA1-regulated gene networks in colon cancer.

Front Med 2016 Jun 6;10(2):178-82. Epub 2016 Apr 6.

Cancer Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, State Key Laboratory of Molecular Oncology, Beijing, 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11684-016-0442-2DOI Listing
June 2016

A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer.

Sci Rep 2016 06 17;6:28083. Epub 2016 Jun 17.

State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep28083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911576PMC
June 2016

Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling.

Oncotarget 2016 Apr;7(14):17957-69

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing 100853, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.7647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951263PMC
April 2016

Methylation of ZNF331 Promotes Cell Invasion and Migration in Human Esophageal Cancer.

Curr Protein Pept Sci 2015 ;16(4):322-8

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing, China.

View Article

Download full-text PDF

Source
January 2016

Enhanced Expression of miR-425 Promotes Esophageal Squamous Cell Carcinoma Tumorigenesis by Targeting SMAD2.

J Genet Genomics 2015 Nov 9;42(11):601-611. Epub 2015 Oct 9.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jgg.2015.09.010DOI Listing
November 2015

BRCA1 regulates transforming growth factor-β (TGF-β1) signaling through Gadd45a by enhancing the protein stability of Smad4.

Mol Oncol 2015 Oct 14;9(8):1655-66. Epub 2015 May 14.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molonc.2015.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528796PMC
October 2015

Feed-Forward Reciprocal Activation of PAFR and STAT3 Regulates Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer.

Cancer Res 2015 Oct 10;75(19):4198-210. Epub 2015 Sep 10.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/content/early/2015/09/17/0
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-15-1062DOI Listing
October 2015

Accessing Genetic Information with Liquid Biopsies.

Trends Genet 2015 Oct;31(10):564-575

Oncology, Illumina, Inc., 5200 Illumina Way, San Diego, CA 92122, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tig.2015.06.001DOI Listing
October 2015

Epigenetic changes and functional study of HOXA11 in human gastric cancer.

Epigenomics 2015 15;7(2):201-13. Epub 2015 Jan 15.

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.14.92DOI Listing
September 2015

Dasatinib enhances cisplatin sensitivity in human esophageal squamous cell carcinoma (ESCC) cells via suppression of PI3K/AKT and Stat3 pathways.

Arch Biochem Biophys 2015 Jun 2;575:38-45. Epub 2015 Apr 2.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100191, China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00039861140039
Publisher Site
http://dx.doi.org/10.1016/j.abb.2014.11.008DOI Listing
June 2015

Nicotine activates YAP1 through nAChRs mediated signaling in esophageal squamous cell cancer (ESCC).

PLoS One 2014 12;9(3):e90836. Epub 2014 Mar 12.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090836PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951250PMC
May 2015

Epigenetic silencing BCL6B induced colorectal cancer proliferation and metastasis by inhibiting P53 signaling.

Am J Cancer Res 2015 15;5(2):651-62. Epub 2015 Jan 15.

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital #28 Fuxing Road, Beijing 100853, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396025PMC
May 2015

Receptor interactive protein kinase 3 promotes Cisplatin-triggered necrosis in apoptosis-resistant esophageal squamous cell carcinoma cells.

PLoS One 2014 24;9(6):e100127. Epub 2014 Jun 24.

State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Center of Basic Medical Sciences, Navy General Hospital, Beijing, China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100127PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069059PMC
March 2015

Overexpression of OLC1 promotes tumorigenesis of human esophageal squamous cell carcinoma.

PLoS One 2014 7;9(3):e90958. Epub 2014 Mar 7.

State Key Laboratory of Molecular Oncology, Cancer Institute & Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090958PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946619PMC
February 2015

MTA1 downregulation inhibits malignant potential in a small cell lung cancer cell line.

Oncol Rep 2015 Feb 12;33(2):885-92. Epub 2014 Dec 12.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing 100021, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/or.2014.3671DOI Listing
February 2015

Joining forces to drive biomedical translation.

Sci Transl Med 2015 Feb;7(275):275ed1

Tim Z. Shi, Hong Liang, and Xiaokun Liang are the Executive Director, Project Manager, and Educator, respectively, at the GlobalMD Organization, Beijing Office, Beijing, China.Qimin Zhan is Vice President and Professor at the Chinese Academy of Medical Sciences, State Key Laboratory of Molecular Oncology Cancer Institute, Cancer Hospital Peking Union Medical College, Beijing, China.Kerong Dai is Director and Professor at Bone and Joint Research Center, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.Barbara M. Alving is Professor at University of Maryland, School of Public Health, College Park, Maryland, USA.Depei Liu is Professor at Chinese Academy of Medical Sciences, Institute of Basic Medical Sciences, Beijing, China.Jianping Dai is Vice Chairman of the Chinese Medical Association and Professor at Beijing Capital Medical University, Beijing Tiantan Hospital, Beijing, China.Anantha Shekhar is Senior Vice Dean at University of Indiana, Institute of Clinical and Translational Sciences, Indianapolis, IN, USA.Xiaobing Fu is Director and Professor at Chinese PLA General Hospital, Institute of Basic Medical Sciences, Beijing, China. Corresponding author. E-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.aaa2363DOI Listing
February 2015

A microRNA signature predicts survival in early stage small-cell lung cancer treated with surgery and adjuvant chemotherapy.

PLoS One 2014 17;9(3):e91388. Epub 2014 Mar 17.

Department of Radiation Oncology, Cancer Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091388PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956664PMC
January 2015

MTA1 regulates higher-order chromatin structure and histone H1-chromatin interaction in-vivo.

Mol Oncol 2015 Jan 27;9(1):218-35. Epub 2014 Aug 27.

State Key Laboratory of Molecular Oncology, Cancer Institute/Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molonc.2014.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528677PMC
January 2015

Aurora-A enhances malignant development of esophageal squamous cell carcinoma (ESCC) by phosphorylating β-catenin.

Mol Oncol 2015 Jan 27;9(1):249-59. Epub 2014 Aug 27.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.17 Panjiayuan South Road, Chaoyang District, Beijing 10021, PR China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molonc.2014.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528673PMC
January 2015

Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxel.

Genes Cancer 2015 Jan;6(1-2):38-48

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362483PMC
January 2015

Enriched CD44(+)/CD24(-) population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC).

Cancer Lett 2014 Oct 14;353(2):153-9. Epub 2014 Aug 14.

Department of Medical Oncology, Cancer Hospital/Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2014.06.022DOI Listing
October 2014

TRAP1 shows clinical significance and promotes cellular migration and invasion through STAT3/MMP2 pathway in human esophageal squamous cell cancer.

J Genet Genomics 2014 Oct 3;41(10):529-37. Epub 2014 Sep 3.

State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jgg.2014.08.004DOI Listing
October 2014

Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations.

Authors:
Chen Wu Zhaoming Wang Xin Song Xiao-Shan Feng Christian C Abnet Jie He Nan Hu Xian-Bo Zuo Wen Tan Qimin Zhan Zhibin Hu Zhonghu He Weihua Jia Yifeng Zhou Kai Yu Xiao-Ou Shu Jian-Min Yuan Wei Zheng Xue-Ke Zhao She-Gan Gao Zhi-Qing Yuan Fu-You Zhou Zong-Min Fan Ji-Li Cui Hong-Li Lin Xue-Na Han Bei Li Xi Chen Sanford M Dawsey Linda Liao Maxwell P Lee Ti Ding You-Lin Qiao Zhihua Liu Yu Liu Dianke Yu Jiang Chang Lixuan Wei Yu-Tang Gao Woon-Puay Koh Yong-Bing Xiang Ze-Zhong Tang Jin-Hu Fan Jing-Jing Han Sheng-Li Zhou Peng Zhang Dong-Yun Zhang Yuan Yuan Ying Huang Chunling Liu Kan Zhai Yan Qiao Guangfu Jin Chuanhai Guo Jianhua Fu Xiaoping Miao Changdong Lu Haijun Yang Chaoyu Wang William A Wheeler Mitchell Gail Meredith Yeager Jeff Yuenger Er-Tao Guo Ai-Li Li Wei Zhang Xue-Min Li Liang-Dan Sun Bao-Gen Ma Yan Li Sa Tang Xiu-Qing Peng Jing Liu Amy Hutchinson Kevin Jacobs Carol Giffen Laurie Burdette Joseph F Fraumeni Hongbing Shen Yang Ke Yixin Zeng Tangchun Wu Peter Kraft Charles C Chung Margaret A Tucker Zhi-Chao Hou Ya-Li Liu Yan-Long Hu Yu Liu Li Wang Guo Yuan Li-Sha Chen Xiao Liu Teng Ma Hui Meng Li Sun Xin-Min Li Xiu-Min Li Jian-Wei Ku Ying-Fa Zhou Liu-Qin Yang Zhou Wang Yin Li Qirenwang Qige Wen-Jun Yang Guang-Yan Lei Long-Qi Chen En-Min Li Ling Yuan Wen-Bin Yue Ran Wang Lu-Wen Wang Xue-Ping Fan Fang-Heng Zhu Wei-Xing Zhao Yi-Min Mao Mei Zhang Guo-Lan Xing Ji-Lin Li Min Han Jing-Li Ren Bin Liu Shu-Wei Ren Qing-Peng Kong Feng Li Ilyar Sheyhidin Wu Wei Yan-Rui Zhang Chang-Wei Feng Jin Wang Yu-Hua Yang Hong-Zhang Hao Qi-De Bao Bao-Chi Liu Ai-Qun Wu Dong Xie Wan-Cai Yang Liang Wang Xiao-Hang Zhao Shu-Qing Chen Jun-Yan Hong Xue-Jun Zhang Neal D Freedman Alisa M Goldstein Dongxin Lin Philip R Taylor Li-Dong Wang Stephen J Chanock

Nat Genet 2014 Sep 17;46(9):1001-1006. Epub 2014 Aug 17.

Division of Cancer Epidemiology and Genetics, National Cancer Institute (NCI), National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212832PMC
September 2014

The subcellular distribution and function of MTA1 in cancer differentiation.

Oncotarget 2014 Jul;5(13):5153-64

State Key Laboratory of Molecular Oncology; Cancer Institute/Hospital, Peking Union Medical College & ChineseAcademy of Medical Sciences, Beijing, China.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148129PMC
http://dx.doi.org/10.18632/oncotarget.2095DOI Listing
July 2014

[Effects of AS1411 on the apoptosis of taxol-resistant lung adenocarcinoma A549 cell].

Zhonghua Yi Xue Za Zhi 2014 May;94(18):1422-6

State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Email:

View Article

Download full-text PDF

Source
May 2014

Epigenetic silencing of RASSF10 promotes tumor growth in esophageal squamous cell carcinoma.

Discov Med 2014 Apr;17(94):169-78

Institute of Digestive Disease and the Second Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan 450014, China.

View Article

Download full-text PDF

Source
April 2014

Gadd45a regulates hematopoietic stem cell stress responses in mice.

Blood 2014 Feb 26;123(6):851-62. Epub 2013 Dec 26.

Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2013-05-504084DOI Listing
February 2014

Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer.

J Pathol 2013 Jun;230(2):194-204

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/path.4073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061565PMC
June 2013

DNA methylation-mediated repression of miR-886-3p predicts poor outcome of human small cell lung cancer.

Cancer Res 2013 Jun 16;73(11):3326-35. Epub 2013 Apr 16.

The State Key Laboratory of Molecular Oncology, Cancer Hospital and Cancer Institute, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/content/73/11/3326.full.pd
Web Search
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-12-3055DOI Listing
June 2013

Global and targeted metabolomics of esophageal squamous cell carcinoma discovers potential diagnostic and therapeutic biomarkers.

Mol Cell Proteomics 2013 May 8;12(5):1306-18. Epub 2013 Feb 8.

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M112.022830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650341PMC
May 2013

Assessment of data pre-processing methods for LC-MS/MS-based metabolomics of uterine cervix cancer.

Analyst 2013 May;138(9):2669-77

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c3an36818aDOI Listing
May 2013

Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway.

J Biol Chem 2013 Mar 17;288(9):6552-60. Epub 2013 Jan 17.

State Key Laboratory Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M112.418335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585088PMC
March 2013

Liquid chromatography-tandem mass spectrometry-based plasma metabonomics delineate the effect of metabolites' stability on reliability of potential biomarkers.

Anal Chem 2013 Mar 21;85(5):2606-10. Epub 2013 Feb 21.

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ac303576bDOI Listing
March 2013

Overexpression of cyclin B1 antagonizes chemotherapeutic-induced apoptosis through PTEN/Akt pathway in human esophageal squamous cell carcinoma cells.

Cancer Biol Ther 2013 Jan 31;14(1):45-55. Epub 2012 Oct 31.

State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.22627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566051PMC
January 2013

Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells.

J Cell Biochem 2012 Dec;113(12):3643-52

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.24228DOI Listing
December 2012

Inhibition of SOX17 by microRNA 141 and methylation activates the WNT signaling pathway in esophageal cancer.

J Mol Diagn 2012 Nov 21;14(6):577-85. Epub 2012 Aug 21.

Department of Gastroenterology & Hepatology, Chinese PLA General Hospital, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2012.06.004DOI Listing
November 2012

Long non-coding RNA gadd7 interacts with TDP-43 and regulates Cdk6 mRNA decay.

EMBO J 2012 Nov 26;31(23):4415-27. Epub 2012 Oct 26.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/emboj.2012.292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512391PMC
November 2012

CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer.

Cancer Biol Ther 2012 Oct 23;13(12):1152-7. Epub 2012 Aug 23.

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.21344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469472PMC
October 2012

Gadd45a inhibits cell migration and invasion by altering the global RNA expression.

Cancer Biol Ther 2012 Sep 24;13(11):1112-22. Epub 2012 Jul 24.

Cancer Research Institute, Xiangya School of Medicine, Central South University, Changsha, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.21186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461817PMC
September 2012

Novel MUC1 aptamer selectively delivers cytotoxic agent to cancer cells in vitro.

PLoS One 2012 22;7(2):e31970. Epub 2012 Feb 22.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031970PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284512PMC
August 2012

A feasibility study on gene therapy of pancreatic carcinoma with Ad-PUMA.

Cancer Biol Ther 2012 Jul 23;13(9):712-9. Epub 2012 May 23.

State Key Laboratory of Molecular Oncology, Cancer Institute/Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.20552DOI Listing
July 2012

Electric fields generated by synchronized oscillations of microtubules, centrosomes and chromosomes regulate the dynamics of mitosis and meiosis.

Authors:
Yue Zhao Qimin Zhan

Theor Biol Med Model 2012 Jul 2;9:26. Epub 2012 Jul 2.

State key laboratory of molecular oncology, Cancer Institute & Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College, Room 6107, No,17 Pan Jia Yuan Nan Li, Chao Yang District, Bei Jing, 100021, China.

View Article

Download full-text PDF

Source
http://tbiomed.biomedcentral.com/articles/10.1186/1742-4682-
Publisher Site
http://dx.doi.org/10.1186/1742-4682-9-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503562PMC
July 2012

Electric oscillation and coupling of chromatin regulate chromosome packaging and transcription in eukaryotic cells.

Authors:
Yue Zhao Qimin Zhan

Theor Biol Med Model 2012 Jul 3;9:27. Epub 2012 Jul 3.

State key laboratory of molecular oncology, Cancer Institute & Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100021, China.

View Article

Download full-text PDF

Source
http://tbiomed.biomedcentral.com/articles/10.1186/1742-4682-
Publisher Site
http://dx.doi.org/10.1186/1742-4682-9-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472328PMC
July 2012

Involvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53-dependent transcriptional regulation.

J Biol Chem 2012 May 26;287(21):17109-19. Epub 2012 Mar 26.

State Key Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.326975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366841PMC
May 2012

Methylation of TFPI-2 is an early event of esophageal carcinogenesis.

Epigenomics 2012 Apr;4(2):135-46

Department of Gastroenterology & Hepatology, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, Beijing 100853, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.12.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742137PMC
April 2012

IQGAP1 interacts with Aurora-A and enhances its stability and its role in cancer.

Biochem Biophys Res Commun 2012 Apr 29;421(1):64-9. Epub 2012 Mar 29.

State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 17 Pan Jia Yuan Nan Li, Beijing 100021, China.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0006291X120058
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2012.03.112DOI Listing
April 2012

Evaluation of ER-α, ER-Β1 and ER-Β2 expression and correlation with clinicopathologic factors in invasive luminal subtype breast cancers.

Clin Transl Oncol 2012 Mar;14(3):225-31

Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Yong An Road, Beijing 100050, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12094-012-0788-0DOI Listing
March 2012

Overexpression of centrosomal protein Nlp confers breast carcinoma resistance to paclitaxel.

Cancer Biol Ther 2012 Feb;13(3):156-63

Department of Medical Oncology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.13.3.18697DOI Listing
February 2012