Publications by authors named "Qianqian Ding"

19 Publications

  • Page 1 of 1

Comment on the article entitled "Iron deficiency for prognosis in acute coronary syndrome - A systematic review and meta-analysis".

Authors:
Qianqian Ding

Int J Cardiol 2021 Aug 13;336:32. Epub 2021 May 13.

Emergency Department, YiWu Central Hospital, Zhejiang 322000, China. Electronic address:

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2021.05.022DOI Listing
August 2021

TRPC7 regulates the electrophysiological functions of embryonic stem cell-derived cardiomyocytes.

Stem Cell Res Ther 2021 May 3;12(1):262. Epub 2021 May 3.

School of Life Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.

Background: Biological pacemakers consisting of pluripotent stem cell-derived cardiomyocytes are potentially useful for treating bradycardia. However, tachyarrhythmia caused by derived cardiomyocytes themselves is one of main barriers hampering their clinical translation. An in-depth understanding of the mechanisms underlying the spontaneous action potential (a.k.a. automaticity) might provide potential approaches to solve this problem. The aim of this project is to study the role of canonical transient receptor potential isoform 7 (TRPC7) channels in regulating the automaticity of embryonic stem cell-derived cardiomyocytes (ESC-CMs).

Methods And Results: By Western blotting, the expression of TRPC7 was found to be increased during the differentiation of mouse ESC-CMs (mESC-CMs). Adenovirus-mediated TRPC7 knockdown decreased while overexpression increased the frequency of Ca transients (CaTs), local Ca releases (LCRs), and action potentials (APs) as detected by confocal microscopy and whole-cell patch-clamping. TRPC7 was found to be positively associated with the activity of ryanodine receptor 2 (RyR2), sarco/endoplasmic reticulum Ca-ATPase (SERCA), and sodium-calcium exchanger (NCX) but not hyperpolarization-activated, cyclic nucleotide-gated channel (HCN), and inositol trisphosphate receptor (IP3R). Knockdown or overexpression of TRPC7 did not alter the expression of HCN4, Cav1.3, Cav3.1, Cav3.2, IP3R1, RyR2, and SERCA but positively regulated the phosphorylation of RyR2 at S2814 and phospholamban (PLN) at T17. Moreover, the positive regulation of APs by TRPC7 was Ca-dependent, as overexpression of N-terminus of TRPC7 (dominant negative of TRPC7) which diminished the Ca permeability of TRPC7 decreased the AP frequency.

Conclusions: TRPC7 regulates the automaticity of mESC-CMs through two mechanisms. On the one hand, TRPC7 positively regulates the intracellular Ca clock through the regulation of activities of both RyR2 and SERCA; on the other hand, TRPC7 also positively regulates the membrane clock via its influence on NCX activity. Altogether, our study reveals that TRPC7 is a potential drug target to manipulate the action potential firing rate of pluripotent stem cell-derived cardiomyocyte-based biological pacemakers to prevent tachyarrhythmia, a condition that might be encountered after transplantation.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13287-021-02308-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091699PMC
May 2021

A commentary on "Economic evaluation of programs against COVID-19: A systematic review".

Int J Surg 2021 03 10;87:105890. Epub 2021 Feb 10.

Department of Infectious Diseases, YiWu Central Hospital, Zhejiang, 322000, China. Electronic address:

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijsu.2021.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872853PMC
March 2021

Quantitative and Sensitive SERS Platform with Analyte Enrichment and Filtration Function.

Nano Lett 2020 10 3;20(10):7304-7312. Epub 2020 Sep 3.

Institute for Composites Science Innovation, School of Materials Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, China.

Surface-enhanced Raman scattering (SERS) technique with naturally born analyte identification capability can achieve ultrahigh sensitivity. However, the sensitivity and quantification capability of SERS are assumed to be mutually exclusive. Here, we prohibit the formation of the ultrasensitive SERS sites to achieve a high quantification capability through separating the gold (Au) nanorods from approaching each other with thick metal organic framework (MOF) shells. The sensitivity decrease caused by the absence of the ultrasensitive SERS sites is compensated by the analyte enrichment function of a slippery surface. The porous MOF shell around the Au nanorod only allows analytes smaller than the pore size to approach the Au nanorods and contribute to the SERS spectrum within the complex sample, greatly enhancing the analyte identification capability. Overall, we have demonstrated an integrated SERS platform with analyte enrichment and analyte filtration function, realizing sensitive, quantitative, and size selective analyte identification in complex environments.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.nanolett.0c02683DOI Listing
October 2020

PinX1t, a Novel PinX1 Transcript Variant, Positively Regulates Cardiogenesis of Embryonic Stem Cells.

J Am Heart Assoc 2020 03 11;9(6):e010240. Epub 2020 Mar 11.

School of Life Sciences The Chinese University of Hong Kong Hong Kong SAR.

Background Pin2/TRF1-interacting protein, PinX1, was previously identified as a tumor suppressor. Here, we discovered a novel transcript variant of mPinX1 (mouse PinX1), mPinX1t (mouse PinX1t), in embryonic stem cells (ESCs). The aims of this investigation were (1) to detect the presence of mPinX1 and mPinX1t in ESCs and their differentiation derivatives; (2) to investigate the role of mPinX1 and mPinX1t on regulating the characteristics of undifferentiated ESCs and the cardiac differentiation of ESCs; (3) to elucidate the molecular mechanisms of how mPinX1 and mPinX1t regulate the cardiac differentiation of ESCs. Methods and Results By 5' rapid amplification of cDNA ends, 3' rapid amplification of cDNA ends, and polysome fractionation followed by reverse transcription-polymerase chain reaction, mPinX1t transcript was confirmed to be an intact mRNA that is actively translated. Western blot confirmed the existence of mPinX1t protein. Overexpression or knockdown of mPinX1 (both decreased mPinX1t expression) both decreased while overexpression of mPinX1t increased the cardiac differentiation of ESCs. Although both mPinX1 and mPinX1t proteins were found to bind to cardiac transcription factor mRNAs, only mPinX1t protein but not mPinX1 protein was found to bind to nucleoporin 133 protein, a nuclear pore complex component. In addition, mPinX1t-containing cells were found to have a higher cytosol-to-nucleus ratio of cardiac transcription factor mRNAs when compared with that in the control cells. Our data suggested that mPinX1t may positively regulate cardiac differentiation by enhancing export of cardiac transcription factor mRNAs through interacting with nucleoporin 133. Conclusions We discovered a novel transcript variant of mPinX1, the mPinX1t, which positively regulates the cardiac differentiation of ESCs.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1161/JAHA.118.010240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335523PMC
March 2020

In situ-generated [email protected] nanoparticle anchored s-doped carbon nanotubes as dual electrocatalysts for oxygen reduction reaction and hydrogen evolution reaction.

Nanotechnology 2020 Mar 9;31(13):135401. Epub 2019 Dec 9.

Department of Precision Manufacturing Engineering Suzhou Vocational Institute of industrial Technology, Suzhou 215104, People's Republic of China.

Developing low cost and highly robust electrocatalysts for oxygen evolution reaction, hydrogen evolution reaction (HER), and oxygen reduction reaction (ORR) is of great importance for the efficient conversion of sustainable energy sources. Herein, we report a facile pyrolysis strategy for the controllable synthesis of [email protected]/S-CNTs with [email protected] nanoparticles anchored on sulfur-doped carbon nanotubes (CNTs). The obtained [email protected]/S-CNT electrocatalyst exhibits excellent dual-functional catalytic activities under an alkaline condition, an ORR performance with an onset potential of -30 mV, and a half-wave potential of -150 mV (versus Ag/AgCl) while the overpotential for the HER is -1.16 V (versus Ag/AgCl) at a current density of 10 mA cm. It was found that the incorporation of sulfur can regulate the electronic structure of CNTs to accelerate the electron transfer performance and generate new catalytic sites, thus contributing to greatly enhancing both the activity and stability of the catalytic process. This work provides a promising way for the rational design of efficient and robust catalysts for sustainable energy conversion.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1088/1361-6528/ab6007DOI Listing
March 2020

Bioinspired Brochosomes as Broadband and Omnidirectional Surface-Enhanced Raman Scattering Substrates.

J Phys Chem Lett 2019 Nov 10;10(21):6484-6491. Epub 2019 Oct 10.

Institute for Composites Science Innovation, School of Materials Science and Engineering , Zhejiang University , Hangzhou 310027 , China.

Surface-enhanced Raman scattering (SERS) substrates capable of working under laser excitation in a broad wavelength range are highly desirable in diverse application fields. Here, we demonstrate that the bioinspired Ag brochosomes, hollow microscale particles with submicroscale pits, have broadband and omnidirectional SERS performance. The SERS performance of the Ag brochosomes under near-infrared laser excitation makes them promising for applications in biosensing fields, such as the sensitive detection of bacteria and bovine hemoglobin protein. Additionally, the SERS intensity was insensitive to the incident angle of the laser beam, resulting from the spherical structure of the Ag brochosomes. The omnidirectional SERS performance makes the Ag brochosomes have application potential for in-the-field analysis using a hand-held Raman spectrometer for which it is difficult to accurately control the laser beam normal to the SERS substrates. Overall, the broadband and omnidirectional brochosome SERS substrates will find applications in diverse fields, particularly in biomedicine and in-the-field analysis.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jpclett.9b02380DOI Listing
November 2019

ALIX increases protein content and protective function of iPSC-derived exosomes.

J Mol Med (Berl) 2019 06 3;97(6):829-844. Epub 2019 Apr 3.

Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, 130 Dong-An Road, Building 7, Room 214, Shanghai, 200032, China.

Nature of exosome-secreting cells determines exosome content and function. ALIX, involved in exosome biogenesis, promotes cell degeneration. Here, ALIX was knocked out (iPSC-ALIX) and overexpressed (iPSC-ALIX) in induced pluripotent stem cells (iPSCs) using CRISPR-Cas9 and lentiviral transduction, respectively, and the secreted exosomes were analyzed. Exosomes from iPSC-ALIX (exosome-KO), iPSC-ALIX (exosome-over), and their corresponding controls contained 176, 529, 431, and 351 proteins, respectively. Exosome-over showed increased protein levels, while exosome-KO contained fewer protein types without differing in total protein content. ALIX knockout did not affect exosome uptake by endothelial cells. Exosome-over more effectively promoted cell viability than exosome-GFP, in a dose-dependent manner. All exosomes were protective for endothelial cells injured by hydrogen peroxide or cisplatin, as demonstrated by promotion of cell viability, horizontal migration, angiogenic sprouting from aortic rings, and formation of capillary-like structures, inhibition of apoptosis, and maintenance of permeability of endothelial monolayer, although exosome-over and exosome-KO had stronger and weaker effects, respectively. SNX2 was important for ALIX-mediated exosomal function. Beneficial functions of the exosomes were independent of experimental models, targeted cell types, causes of injury, exosome-producing iPSC passages, clones of ALIX knockout, and transfection batches of ALIX overexpression. Thus, we present a novel strategy to manipulate iPSCs for production of exosomes with beneficial ALIX-regulated protein composition for varied exosome functions. KEY MESSAGES: ALIX knockout and overexpression regulate protein profile in iPSC-derived exosome. ALIX knockout decreases therapeutic function of iPSC-derived exosomes. ALIX overexpression increases therapeutic function of iPSC-derived exosomes. Manipulating iPSCs can produce exosomes with more beneficial protein content.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-019-01767-zDOI Listing
June 2019

Water soluble and insoluble components of PM and their functional cardiotoxicities on neonatal rat cardiomyocytes in vitro.

Ecotoxicol Environ Saf 2019 Jan 2;168:378-387. Epub 2018 Nov 2.

Institute of Environmental Health and Pollution Control, School of Environmental Science and Engineering, Guangdong University of Technology, Guangzhou, Guangdong, China; State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong, China. Electronic address:

A growing number of epidemiological surveys show that PM is an important promoter for the cardiovascular dysfunction induced by atmospheric pollution. PM is a complex mixture of solid and liquid airborne particles and its components determine the health risk of PMto a great extent. However, the individual cardiotoxicities of different PM fractions are still unclear, especially in the cellular level. Here we used the neonatal rat cardiomyocytes (NRCMs) to evaluate the cardiac toxicity of PM exposure. The cytotoxicities of Total-PM, water soluble components of PM (WS-PM) and water insoluble components of PM (WIS-PM), which include the cell viability, cell membrane damage, reactive oxygen species (ROS) generation, were examined with NRCMs in vitro. The results indicated that Total-PM or WIS-PM exposure significantly decreased the cell viability, induced the cell membrane damage and increased the ROS level in NRCMs at concentrations above 50 µg/mL. However, WS-PM exposure could induce the cytotoxicity on NRCMs until the concentration of WS-PM was raised to a higher concentration (75 µg/mL). Furthermore, the DNA damage was detected in NRCMs after 48 h of exposure with Total-PM, WS-PM or WIS-PM (75 µg/mL) and the adverse effects on mitochondrial function and action potentials of NRCMs were detected only both in the Total-PM and WIS-PM treatment group. In summary, our project not only estimates the risk of PM on cardiac cells but also reveal that Total-PM and WIS-PM exposure were predominantly associated with the functional cardiotoxicities in NRCMs.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ecoenv.2018.10.107DOI Listing
January 2019

Circumventing silver oxidation induced performance degradation of silver surface-enhanced Raman scattering substrates.

Nanotechnology 2018 Oct 27;29(41):414001. Epub 2018 Jul 27.

Institute for Composites Science Innovation, School of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, People's Republic of China.

Surface-enhanced Raman scattering (SERS) has been recognized as a promising sensing technique in biomedical/biosensing applications and analytical chemistry. Silver (Ag) nanostructures have the strongest SERS enhancement, but suffer from severe enhancement degradation induced by oxidation. Here, we introduce electrochemical reduction of silver oxide to produce Ag SERS substrates on request to partially circumvent the SERS enhancement degradation problem of Ag SERS substrates. Silver oxide nanostructures were first prepared in pure silver citrate aqueous solutions with controllable morphologies depending on the electrodeposition parameters. The transition process from silver oxide to Ag was investigated by density functional theory calculations. Based on the understanding of the transition mechanism, heating treatment, applying reducing agent, and electrochemical reduction were adopted to transform silver oxide to Ag. Notably, no organic agents were introduced neither in the electrodeposition of silver oxide nor electrochemical transformation of silver oxide to Ag. The electrochemical reduction strategy could produce Ag SERS substrates with a 'clean' surface with outstanding SERS performance in a simple as well as cost and time effective manner. Ag SERS substrates can be used in biomedical/biosensing fields. The approach through electrochemical reduction of silver oxide to generate Ag SERS substrate may push forward practical application process of Ag SERS substrates.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1088/1361-6528/aad678DOI Listing
October 2018

Terminal Molecular Isomer-Effect on Supramolecular Self-Assembly System Based on Naphthalimide Derivative and Its Sensing Application for Mercury(II) and Iron(III) Ions.

Langmuir 2018 06 18;34(25):7404-7415. Epub 2018 Jun 18.

College of Chemistry and Chemical Engineering and Henan Province Key laboratory of Utilization of Non-metallic Mineral in the South of Henan, Institute for Conservation and Utilization of Agro-bioresources in Dabie Mountains , Xinyang Normal University , Xinyang 464000 , China.

A series of naphthalimide derivative gelators (G-o, G-m, and G-p) with three molecular isomers as their terminal groups were designed and synthesized. Only G-m and G-p could form stable organogels in some solvents including methanol, acetonitrile, n-hexane, toluene, ethanol, DMSO, DMF, and mixed solvents of acetonitrile/HO (1/1, v/v). The different self-assembly structures were obtained from the self-assembly process of G-o, G-m, and G-p such as structures like a Chinese chestnut formed by irregular micrometer pieces, microbelts, and microbelt structures mingled with the bird's nest structures which exhibited different surface hydrophobicity with water contact angles of 121-139° due to their different intermolecular noncovalent interactions. To our surprise, G-p acetonitrile solution emitted 492 nm light with a red-shift of 72 nm compared with that emitted from G-o and G-m acetonitrile solution under 350 nm light excitation. Three gelators showed different detection abilities toward metal ions. G-o did not have any ability for sensitive and selective detection toward any ion. In contrast, G-m and G-p could sensitively and selectively detect Hg and Fe. The detection limits for Fe and Hg by G-m were 4.76 × 10 M and 7.01 × 10 M with the corresponding association constants ( K) of 1.64 × 10 and 3.79 × 10 M, respectively. The detection limits for Fe and Hg by G-p were 3.26 × 10 and 1.77 × 10 M with the corresponding K of 1.44 × 10 and 1.99 × 10 M, respectively. More interestingly, the back-titration of SCN could distinguish Hg from Fe. At the same time, xerogels G-m and G-p also exhibited responsiveness toward Fe and Hg through fluorescence changes. The photophysical properties, gel formation, hierarchical structures, surface wettability, and their function in this self-assembly system could be tuned through the molecular isomer effect. This work provides a new research paradigm for molecular isomer tuned supramolecular self-assembly materials from noncovalent interaction to molecular function.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.langmuir.8b00991DOI Listing
June 2018

Protective effects of human induced pluripotent stem cell-derived exosomes on high glucose-induced injury in human endothelial cells.

Exp Ther Med 2018 Jun 13;15(6):4791-4797. Epub 2018 Apr 13.

Department of Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, P.R. China.

Exosomes are a family of extracellular vesicles that are secreted from almost all types of cells and are associated with cell-to-cell communication. The present study was performed to investigate the effects of human induced pluripotent stem cell-derived exosomes (hiPSC-exo) on cell viability, capillary-like structure formation and senescence in endothelial cells exposed to high glucose. Exosomes were isolated from the conditional medium of hiPSCs and confirmed by transmission electron microscopy, nanoparticle tracking analysis and western blot analysis using Alix and cluster of differentiation-63 as markers. hiPSC-exo were labeled with PKH26 for tracking, and it was determined that spherical exosomes, with a typical cup-shape, were absorbed by human umbilical vascular endothelial cells (HUVECs). Cultured HUVECs were treated with high glucose (33 mM) with or without hiPSC-exo (20 µg/ml) for 48 h, and cell viability, capillary tube formation and senescence were assessed. When exposed to high glucose, viability and tube formation in HUVECs was significantly reduced (P<0.0001), whereas the proportion of senescent cells was higher compared with that in control HUVECs (P<0.0001). Furthermore, hiPSC-exo restored cell viability and capillary-like structure formation, and reduced senescence in HUVECs exposed to high glucose (P<0.0001). However, hiPSC-exo had minimal effects on normal HUVECs. These findings suggest that stem cell-derived exosomes are able to promote cell proliferation, enhance capillary-like structure formation and reduce senescence in endothelial cells exposed to high glucose.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.3892/etm.2018.6059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958753PMC
June 2018

Effects of ulinastatin combined with mechanical ventilation on oxygen metabolism, inflammation and stress response and antioxidant capacity of ARDS.

Exp Ther Med 2018 Jun 30;15(6):4665-4670. Epub 2018 Mar 30.

Department of Emergency, Yiwu Central Hospital, Yiwu, Zhejiang 322000, P.R. China.

Acute respiratory distress syndrome (ARDS) is a disease that seriously threatens human life and health. The aim of the study was to investigate the effects of ulinastatin combined with mechanical ventilation on oxygen metabolism, inflammation and stress response, as well as the antioxidant capacity of ARDS. Eighty patients with ARDS treated in Yiwu Central Hospital from January, 2015 to December, 2016 were enrolled in the present study and divided into the observation (n=40) and control (n=40) groups, using a random number table. The control group was treated with mechanical ventilation, while the observation group, based on treatment of the control group, was treated with ulinastatin for 14 consecutive days as one course of treatment. The changes in the relevant indexes of oxygen metabolism, lung function, time of ventilator treatment, total hospital stay, and St. George's Respiratory Questionnaire (SGRQ) score of the two groups after intervention were compared, and the changes in inflammatory cytokine levels, dopamine receptor-related hormone levels, superoxide dismutase (SOD), malondialdehyde (MDA) and total antioxidant capacity of the two groups before intervention and at 1 and 4 weeks after intervention were compared. After intervention, the arterial blood lactate in the observation group was significantly lower than that in the control group (P<0.05), the oxygen uptake rate was significantly higher than that in the control group (P<0.05) and the arterial oxygen content was significantly higher than that in the control group (P<0.05). In the lung function indexes, the FEV and FEV/FVC levels in the observation group were smaller than those in the control group (P<0.05), the duration of ventilator treatment was significantly shorter than that in the control group (P<0.05), and the hospital stay was significantly less than that in the control group (P<0.05). Prior to intervention, SGRQ scores in the two groups were not statistically significant (P>0.05). At 1 and 4 weeks after intervention, the SGRQ scores of the observation group were significantly increased to those of the control group (P<0.05). The tumor levels of necrosis factor-α (TNF-α), interleukin-6 (IL-6) and CRP were significantly lower than those of the control group (P<0.05). The levels of adrenaline and norepinephrine were significantly lower than those of the control group (P<0.05). The levels of MDA, SOD and the total antioxidant capacity were significantly increased to those of control group (P<0.05). The application of ulinastatin combined with mechanical ventilation in ARDS patients is of great significance in improving the oxygen delivery-consumption balance of body, increasing the lung function, reducing the inflammatory and stress response, and improving the antioxidant capacity.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.3892/etm.2018.6012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952097PMC
June 2018

Strong Blue Emissive Supramolecular Self-Assembly System Based on Naphthalimide Derivatives and Its Ability of Detection and Removal of 2,4,6-Trinitrophenol.

Langmuir 2017 08 27;33(31):7788-7798. Epub 2017 Jul 27.

Department of Chemistry and Collaborative Innovation Center of Energy Materials, Fudan University , Shanghai 200433, China.

Two simple and novel gelators (G-P with pyridine and G-B with benzene) with different C-4 substitution groups on naphthalimide derivatives have been designed and characterized. Two gelators could form organogels in some solvents or mixed solvents. The self-assembly processes of G-P in a mixed solvent of acetonitrile/HO (1/1, v/v) and G-B in acetonitrile were studied by means of electron microscopy and spectroscopy. The organogel of G-P in the mixed solvent of acetonitrile/HO (1/1, v/v) formed an intertwined fiber network, and its emission spectrum had an obvious blue shift compared with that of solution. By contrast, the organogel of G-B in acetonitrile formed a straight fiber, and its emission had an obvious red shift compared with that of solution. G-P and G-B were employed in detecting nitroaromatic compounds because of their electron-rich property. G-P is more sensitive and selective toward 2,4,6-trinitrophenol (TNP) compared with G-B. The sensing mechanisms were investigated by H NMR spectroscopic experiments and theoretical calculations. From these experimental results, it is proposed that electron transfer occurs from the electron-rich G-P molecule to the electron-deficient TNP because of the possibility of complex formation between G-P and TNP. The G-P molecule could detect TNP in water, organic solvent media, as well as using test strips. It is worth mentioning that the organogel G-P can not only detect TNP but also remove TNP from the solution into the organogel system.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.langmuir.7b01927DOI Listing
August 2017

A dual response organogel system based on an iridium complex and a Eu(iii) hybrid for volatile acid and organic amine vapors.

Soft Matter 2017 May;13(20):3802-3811

College of Chemistry and Chemical Engineering & Henan Province Key laboratory of Utilization of Non-metallic Mineral in the South of Henan, Institute for Conservation and Utilization of Agro-bioresources in Dabie Mountains, Xinyang Normal University, Xinyang 464000, China.

A thiophene-based hybrid organogel system consisting of complex iridium (Ir) and EuCl·6HO was designed and synthesized to realize dual responses to volatile acids and organic amine vapors. The photophysical properties and self-assembly of compound 1 and the hybrid organogel were also studied. Compound 1 could gelate some organic solvents and self-assemble into 3D nanofibers in the gels. The stable hybrid organogel 1-Ir-Eu could be obtained after addition of complex Ir and EuCl·6HO. FTIR spectral results showed that the hydrogen bond still remained even upon addition of complex Ir, EuCl·6HO, NaOH and CFCOOH to organogel 1. Interestingly, the emission properties of the hybrid organogel 1-Ir-Eu could undergo interconversion between cyan light and red light via addition of NaOH and CFCOOH. The emission properties of xerogel film 1-Ir-Eu obtained in the presence of NaOH could also undergo fast and reversible transition in response to volatile acids such as CFCOOH, formic acid, acetic acid, propionic acid and organic amine vapors such as ammonium hydroxide, EtN, tripropylamine, and ethylenediamine. The emission spectral change of Ir-Eu in the organogel or xerogel in the presence of base and acid demonstrated the formation of a new complex between complex Ir and EuCl·6HO. This dual-response process could be repeated many times. Contact angle experiment results further showed the morphology and internal components of the xerogel film surface in the process of response to gaseous CFCOOH and EtN. This work provides a method for producing multifunctional supramolecular materials for sensing volatile acids and organic amine vapors.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1039/c7sm00714kDOI Listing
May 2017

Regulation gel formation, hierarchical structures and surface wettability via isomeride effect in supramolecular organogel system.

J Colloid Interface Sci 2017 05 25;494:170-177. Epub 2017 Jan 25.

College of Chemistry and Chemical Engineering & Henan Province Key Laboratory of Utilization of Non-metallic Mineral in the South of Henan, Institute for Conservation and Utilization of Agro-Bioresources in Dabie Mountains, Xinyang Normal University, Xinyang 464000, China.

A new serial of gelators with two cholesteryl groups based on o-phenylenediamine, m-phenylenediamine and p-phenylenediamine were synthesized, and their organogelation ability was evaluated. We found that G-o could form gels in DMF, DMSO and ethyl acetate, G-m and G-p could only gel DMF and 1,4-dioxane. The organogels were thoroughly characterized using various microscopic techniques including field-emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), UV-Vis spectrum, FT-IR spectrum and contact angle. The gelation ability, morphology, self-assembly mode and materials surface wettability all could be tuned via isomeride effect in self-assembly system. Interestingly, superhydrophobic surface was formed via the self-assembly of compound G-p in 1,4-dioxane and exhibited very high adsorption capacity for water. This gel system provided new method for modulation self-assembly process in supramolecular field.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcis.2017.01.080DOI Listing
May 2017

Ultrafast Dynamics of Plasmon-Exciton Interaction of Ag Nanowire- Graphene Hybrids for Surface Catalytic Reactions.

Sci Rep 2016 09 7;6:32724. Epub 2016 Sep 7.

Department of Applied Physics, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, People's Republic of China.

Using the ultrafast pump-probe transient absorption spectroscopy, the femtosecond-resolved plasmon-exciton interaction of graphene-Ag nanowire hybrids is experimentally investigated, in the VIS-NIR region. The plasmonic lifetime of Ag nanowire is about 150 ± 7 femtosecond (fs). For a single layer of graphene, the fast dynamic process at 275 ± 77 fs is due to the excitation of graphene excitons, and the slow process at 1.4 ± 0.3 picosecond (ps) is due to the plasmonic hot electron interaction with phonons of graphene. For the graphene-Ag nanowire hybrids, the time scale of the plasmon-induced hot electron transferring to graphene is 534 ± 108 fs, and the metal plasmon enhanced graphene plasmon is about 3.2 ± 0.8 ps in the VIS region. The graphene-Ag nanowire hybrids can be used for plasmon-driven chemical reactions. This graphene-mediated surface-enhanced Raman scattering substrate significantly increases the probability and efficiency of surface catalytic reactions co-driven by graphene-Ag nanowire hybridization, in comparison with reactions individually driven by monolayer graphene or single Ag nanowire. This implies that the graphene-Ag nanowire hybrids can not only lead to a significant accumulation of high-density hot electrons, but also significantly increase the plasmon-to-electron conversion efficiency, due to strong plasmon-exciton coupling.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep32724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013321PMC
September 2016

Effect of aqueous and ambient atmospheric environments on plasmon-driven selective reduction reactions.

Sci Rep 2015 Jun 1;5:10269. Epub 2015 Jun 1.

Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, People's Republic of China.

We successfully realised plasmon-driven selective reduction reactions of 2-amino-5-nitrobenzenethiol (2A-5-NBT) to 3,3'-dimercapto-4,4'-diaminoazobenzene , an azobenzene derivative, using surface-enhanced Raman scattering (SERS) spectroscopy, and supported by the theoretical calculations. The SERS spectra demonstrated that two 5-nitro groups of 2A-5-NBTs were selectively reduced to the -N=N- chemical bond of 3,3'-dimercapto-4,4'-diaminoazobenzene, whereas the 2-amine group of 2A-5-NBT remained unchanged. Our experimental results revealed that aqueous environments were preferable to ambient atmospheric environments for this selective reduction reaction. The product is very stable in aqueous environments. However, in ambient atmosphere environments, the product is not stable and can revert back to 2A-5-NBT, where the -N=N- chemical bond can be broken by plasmon scissors. The plasmon-induced catalytic reactions in aqueous environments could be used for the efficient synthesis of aromatic azobenzene derivative compounds, which are valuable chemicals that are widely used in the chemical industry as dyes, food additives and drugs.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep10269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450751PMC
June 2015

Sea-urchin-like [email protected]@Ag particles: an efficient SERS substrate for detection of organic pollutants.

Nanoscale 2013 Jul 22;5(13):5887-95. Epub 2013 May 22.

Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei 230031, PR China.

Ag-coated sea-urchin-like [email protected] core-shell particles can be synthesized by a facile one-step solvothermal method, followed by deposition of high-density Ag nanoparticles onto the carbon surface through an in situ growth process, respectively. The as-synthesized Ag-coated [email protected] particles can be used as a surface-enhanced Raman scattering (SERS) substrate holding reproducible properties under an external magnetic force. The magnetic function of the particles allows concentrating the composite particles into small spatial regions, which can be exploited to decrease the amount of material per analysis while improving its SERS detection limit. In contrast to the traditional SERS substrates, the present [email protected]@Ag particles hold the advantages of enrichment of organic pollutants for improving SERS detection limit and recycled utilization.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1039/c3nr01273eDOI Listing
July 2013