Qianjin Lu

Qianjin Lu

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Clinical significance and immunobiology of IL-21 in autoimmunity.

J Autoimmun 2019 May 14;99:1-14. Epub 2019 Feb 14.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2019.01.013DOI Listing
May 2019

Therapeutic advances in the treatment of SLE.

Int Immunopharmacol 2019 Apr 16;72:218-223. Epub 2019 Apr 16.

Department of Dermatology, The Second Xiangya Hospital of Central South University, Hunan Key Laboratory of Medical Epigenomics, 139 Middle Renmin Road, Changsha, Hunan 410011, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15675769193047
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http://dx.doi.org/10.1016/j.intimp.2019.03.010DOI Listing
April 2019

Elevated histone H3 acetylation is associated with genes involved in T lymphocyte activation and glutamate decarboxylase antibody production in patients with type 1 diabetes.

J Diabetes Investig 2019 Jan 26;10(1):51-61. Epub 2018 Jun 26.

Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1111/jdi.12867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319479PMC
January 2019

The Therapeutic and Pathogenic Role of Autophagy in Autoimmune Diseases.

Front Immunol 2018 31;9:1512. Epub 2018 Jul 31.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.3389/fimmu.2018.01512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080611PMC
January 2019

The Aberrant Epigenetic Modifications in the Pathogenesis of Psoriasis.

J Investig Dermatol Symp Proc 2018 Dec;19(2):S81-S82

Department of Dermatology, The Second Xiangya Hospital of Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.jisp.2018.09.007DOI Listing
December 2018

Epigenetics as biomarkers in autoimmune diseases.

Clin Immunol 2018 Nov 21;196:34-39. Epub 2018 Mar 21.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.03.011DOI Listing
November 2018

All-Trans Retinoic Acid Induces CD4+CD25+FOXP3+ Regulatory T Cells by Increasing FOXP3 Demethylation in Systemic Sclerosis CD4+ T Cells.

J Immunol Res 2018 30;2018:8658156. Epub 2018 Apr 30.

Department of Dermatology, Second Xiangya Hospital, Central South University, 139 Ren-Min Road, Changsha 410011, China.

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http://dx.doi.org/10.1155/2018/8658156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952589PMC
October 2018

Overexpression of Wilms' tumor 1 in skin lesions of psoriasis is associated with abnormal proliferation and apoptosis of keratinocytes.

Mol Med Rep 2018 Oct 16;18(4):3973-3982. Epub 2018 Aug 16.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China.

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http://dx.doi.org/10.3892/mmr.2018.9391DOI Listing
October 2018

Molecular Control of Follicular Helper T cell Development and Differentiation.

Front Immunol 2018 25;9:2470. Epub 2018 Oct 25.

Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02470
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http://dx.doi.org/10.3389/fimmu.2018.02470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209674PMC
October 2018

Crosstalk between metabolism and epigenetic modifications in autoimmune diseases: a comprehensive overview.

Cell Mol Life Sci 2018 Sep 4;75(18):3353-3369. Epub 2018 Jul 4.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, No. 139 Renmin Middle Rd, Changsha, 410011, Hunan, China.

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http://dx.doi.org/10.1007/s00018-018-2864-2DOI Listing
September 2018

Pathogenic role of tissue-resident memory T cells in autoimmune diseases.

Autoimmun Rev 2018 Sep 10;17(9):906-911. Epub 2018 Jul 10.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2018.03.014DOI Listing
September 2018

A comprehensive review of immune-mediated dermatopathology in systemic lupus erythematosus.

J Autoimmun 2018 Sep 11;93:1-15. Epub 2018 Jul 11.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2018.07.007DOI Listing
September 2018

A rare case report for dermatomyofibroma in nasion.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Sep;43(9):1037-1040

Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.

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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.09.017DOI Listing
September 2018

Dysregulation of microRNAs in autoimmune diseases: Pathogenesis, biomarkers and potential therapeutic targets.

Cancer Lett 2018 Aug 20;428:90-103. Epub 2018 Apr 20.

Department of Dermatology, The Second Xiangya Hospital of Central South University, Hunan Key Laboratory of Medical Epigenomics, 139 Middle Renmin Road, Changsha, Hunan, 410011, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.04.016DOI Listing
August 2018

Epigenetic regulation in B-cell maturation and its dysregulation in autoimmunity.

Cell Mol Immunol 2018 Jul 29;15(7):676-684. Epub 2018 Jan 29.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, 410011, Changsha, Hunan, China.

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http://dx.doi.org/10.1038/cmi.2017.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123482PMC
July 2018

STAT3-mediated epigenetic silencing of FOXP3 in LADA T cells is regulated through HDAC5 and DNMT1.

Clin Immunol 2018 Jun 6;191:116-125. Epub 2017 Dec 6.

Institute of Metabolism and Endocrinology, The Second Xiangya Hospital and the Diabetes Center, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, Central South University, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.12.001DOI Listing
June 2018

Genetic and epigenetic influences on the loss of tolerance in autoimmunity.

Cell Mol Immunol 2018 Jun 5;15(6):575-585. Epub 2018 Mar 5.

Department of Dermatology, The Second Xiangya Hospital of Central South University, 139 Middle Renmin Road, 410011, Changsha, Hunan, China.

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http://dx.doi.org/10.1038/cmi.2017.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079019PMC
June 2018

MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation.

J Clin Invest 2018 Jun 14;128(6):2551-2568. Epub 2018 May 14.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1172/JCI97426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983326PMC
June 2018

Down-regulation of MBD4 contributes to hypomethylation and overexpression of CD70 in CD4 T cells in systemic lupus erythematosus.

Clin Epigenetics 2017 22;9:104. Epub 2017 Sep 22.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011 China.

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http://dx.doi.org/10.1186/s13148-017-0405-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610447PMC
May 2018

Translating epigenetics into clinic: focus on lupus.

Clin Epigenetics 2017 2;9:78. Epub 2017 Aug 2.

Department of Dermatology, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, Hunan 410011 China.

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http://dx.doi.org/10.1186/s13148-017-0378-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541721PMC
April 2018

Risk of adverse events from different drugs for SLE: a systematic review and network meta-analysis.

Lupus Sci Med 2018 9;5(1):e000253. Epub 2018 Mar 9.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.1136/lupus-2017-000253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890859PMC
March 2018

IL-6/STAT3 pathway induced deficiency of RFX1 contributes to Th17-dependent autoimmune diseases via epigenetic regulation.

Nat Commun 2018 02 8;9(1):583. Epub 2018 Feb 8.

Department of Dermatology, The Second Xiangya Hospital of Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, 410011, China.

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http://dx.doi.org/10.1038/s41467-018-02890-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805701PMC
February 2018

Regulatory effects of Nr4a2 on Th2 cells from patients with pemphigus vulgaris.

Oncotarget 2018 Feb 1;9(13):11258-11267. Epub 2018 Feb 1.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.

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http://dx.doi.org/10.18632/oncotarget.24371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834247PMC
February 2018

Anti-N-methyl-d-aspartate receptor encephalitis in children of Central South China: Clinical features, treatment, influencing factors, and outcomes.

J Neuroimmunol 2017 11 11;312:59-65. Epub 2017 Sep 11.

Department of Pediatrics, Xiangya Hospital, Central South University, Changsha, China; Hunan Intellectual and Developmental Disabilities Research Center, China. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2017.09.005DOI Listing
November 2017

[A case report of subcutaneous panniculitis-like T cell lymphoma with fever and erythema on the body as the initial symptoms].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2017 Nov;42(11):1348-1352

Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.

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http://dx.doi.org/10.11817/j.issn.1672-7347.2017.11.017DOI Listing
November 2017

The epigenetic mechanism for discordance of autoimmunity in monozygotic twins.

J Autoimmun 2017 Sep 12;83:43-50. Epub 2017 Apr 12.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.04.003DOI Listing
September 2017

Induction and maintenance of regulatory T cells by transcription factors and epigenetic modifications.

J Autoimmun 2017 Sep 11;83:113-121. Epub 2017 Jul 11.

Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.07.002DOI Listing
September 2017

DNA methylation/hydroxymethylation in melanoma.

Oncotarget 2017 Sep 30;8(44):78163-78173. Epub 2017 May 30.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China.

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http://dx.doi.org/10.18632/oncotarget.18293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652847PMC
September 2017

Critical role of environmental factors in the pathogenesis of psoriasis.

J Dermatol 2017 Aug 27;44(8):863-872. Epub 2017 Mar 27.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, Second Xiangya Hospital of Central South University, Changsha, China.

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http://dx.doi.org/10.1111/1346-8138.13806DOI Listing
August 2017

Effectiveness and Safety of Different Once-Daily Doses of Adrenocorticotropic Hormone for Infantile Spasms.

Paediatr Drugs 2017 Aug;19(4):357-365

Department of Pediatrics, Xiangya Hospital, Central South University, Xiangya Road 87, Changsha, Hunan, China.

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http://dx.doi.org/10.1007/s40272-017-0225-5DOI Listing
August 2017

Novel biomarkers for systemic lupus erythematosus.

Biomark Med 2017 Aug 3;11(8):677-686. Epub 2017 Aug 3.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.

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http://dx.doi.org/10.2217/bmm-2016-0379DOI Listing
August 2017

Epigenetics of CD4+ T cells in autoimmune diseases.

Curr Opin Rheumatol 2017 07;29(4):361-368

aDepartment of Dermatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China bDivision of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, Davis, California, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000393DOI Listing
July 2017

The role of basic leucine zipper transcription factor E4BP4 in the immune system and immune-mediated diseases.

Clin Immunol 2017 07 30;180:5-10. Epub 2017 Mar 30.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, No. 139, Renmin Road, Changsha 410011, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.03.013DOI Listing
July 2017

Histone demethylase JMJD3 regulates CD11a expression through changes in histone H3K27 tri-methylation levels in CD4+ T cells of patients with systemic lupus erythematosus.

Oncotarget 2017 Jul;8(30):48938-48947

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China.

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http://dx.doi.org/10.18632/oncotarget.16894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564738PMC
July 2017

[A case of nasal NK/T-cell lymphoma].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2017 Jul;42(7):860-864

Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha 410011, China.

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http://dx.doi.org/10.11817/j.issn.1672-7347.2017.07.020DOI Listing
July 2017

Epigenetic Alterations in Cellular Immunity: New Insights into Autoimmune Diseases.

Cell Physiol Biochem 2017 8;41(2):645-660. Epub 2017 Feb 8.

Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1159/000457944DOI Listing
June 2017

Epigenetic Variability of CD4+CD25+ Tregs Contributes to the Pathogenesis of Autoimmune Diseases.

Clin Rev Allergy Immunol 2017 Apr;52(2):260-272

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, China.

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http://dx.doi.org/10.1007/s12016-016-8590-3DOI Listing
April 2017

Beyond Genetics: What Causes Type 1 Diabetes.

Clin Rev Allergy Immunol 2017 Apr;52(2):273-286

Diabetes Center, 2nd Xiangya Hospital, and Institute of Metabolism and Endocrinology, Key Laboratory of Diabetes Immunology, Ministry of Education, Central South University, 139 Renmin Middle Rd, Changsha, Hunan, 410011, China.

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http://dx.doi.org/10.1007/s12016-016-8592-1DOI Listing
April 2017

Organ-specific biomarkers in lupus.

Autoimmun Rev 2017 Apr 14;16(4):391-397. Epub 2017 Feb 14.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2017.02.011DOI Listing
April 2017

The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis.

Cell Mol Immunol 2017 Mar 21;14(3):276-284. Epub 2015 Sep 21.

Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA 95616, USA.

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http://dx.doi.org/10.1038/cmi.2015.86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360882PMC
March 2017

Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity.

Autoimmunity 2017 Mar 21;50(2):71-81. Epub 2017 Feb 21.

a Department of Dermatology , Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics , Changsha , China and.

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http://dx.doi.org/10.1080/08916934.2017.1284821DOI Listing
March 2017

Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials.

Hum Immunol 2017 Feb 28;78(2):120-128. Epub 2016 Dec 28.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.humimm.2016.12.010DOI Listing
February 2017

Aberrant Epigenetic Regulation in the Pathogenesis of Systemic Lupus Erythematosus and Its Implication in Precision Medicine.

Cytogenet Genome Res 2016 9;149(3):141-155. Epub 2016 Sep 9.

Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, PR China.

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http://dx.doi.org/10.1159/000448793DOI Listing
January 2017

The Genetics and Epigenetics of Atopic Dermatitis-Filaggrin and Other Polymorphisms.

Clin Rev Allergy Immunol 2016 Dec;51(3):315-328

Hunan Key Laboratory of Medical Epigenomics & Department of Dermatology, The Second Xiangya Hospital, Central South University, 139 Renmin Middle Rd, Changsha, Hunan, 410011, China.

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http://dx.doi.org/10.1007/s12016-015-8508-5DOI Listing
December 2016

The expression of Bcl-6 in circulating follicular helper-like T cells positively correlates with the disease activity in systemic lupus erythematosus.

Clin Immunol 2016 Dec 3;173:161-170. Epub 2016 Nov 3.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.10.017DOI Listing
December 2016

Distinct epigenomes in CD4 T cells of newborns, middle-ages and centenarians.

Sci Rep 2016 12 5;6:38411. Epub 2016 Dec 5.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha 410011, PR. China.

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http://dx.doi.org/10.1038/srep38411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137168PMC
December 2016

Dysregulation of Cell Death and Its Epigenetic Mechanisms in Systemic Lupus Erythematosus.

Molecules 2016 Dec 27;22(1). Epub 2016 Dec 27.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha 410011, China.

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http://dx.doi.org/10.3390/molecules22010030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155917PMC
December 2016

Induced Regulatory T Cells: Their Development, Stability, and Applications.

Trends Immunol 2016 11 9;37(11):803-811. Epub 2016 Sep 9.

Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.it.2016.08.012DOI Listing
November 2016

The important roles of type I interferon and interferon-inducible genes in systemic lupus erythematosus.

Int Immunopharmacol 2016 Nov 18;40:542-549. Epub 2016 Oct 18.

Department of Dermatology, Second Xiangya Hospital of Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2016.10.012DOI Listing
November 2016

The critical role of epigenetics in systemic lupus erythematosus and autoimmunity.

J Autoimmun 2016 11 6;74:118-138. Epub 2016 Jul 6.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.06.020DOI Listing
November 2016

Recent advances of exosomes in immune modulation and autoimmune diseases.

Autoimmunity 2016 09 3;49(6):357-365. Epub 2016 Jun 3.

b Department of Dermatology , Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics , Changsha , P.R. China , and.

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http://dx.doi.org/10.1080/08916934.2016.1191477DOI Listing
September 2016

Histone Posttranslational Modifications of CD4⁺ T Cell in Autoimmune Diseases.

Int J Mol Sci 2016 Sep 22;17(10). Epub 2016 Sep 22.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha 410011, China.

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http://dx.doi.org/10.3390/ijms17101547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085618PMC
September 2016

Transcription factor RFX1 is ubiquitinated by E3 ligase STUB1 in systemic lupus erythematosus.

Clin Immunol 2016 08 6;169:1-7. Epub 2016 Jun 6.

Department of Dermatology and Epigenetic Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.06.003DOI Listing
August 2016

The key culprit in the pathogenesis of systemic lupus erythematosus: Aberrant DNA methylation.

Autoimmun Rev 2016 Jul 10;15(7):684-9. Epub 2016 Mar 10.

Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, Second Xiangya Hospital, Central South UniversityChangsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2016.03.002DOI Listing
July 2016

Integrated analysis of mRNA, microRNA and protein in systemic lupus erythematosus-specific induced pluripotent stem cells from urine.

BMC Genomics 2016 07 11;17:488. Epub 2016 Jul 11.

Clinical Medical Research Center, The Second Clinical Medical College of Jinan University (Shenzhen People's Hospital), Shenzhen, Guangdong, 518020, People's Republic of China.

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http://dx.doi.org/10.1186/s12864-016-2809-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940874PMC
July 2016

Characters, functions and clinical perspectives of long non-coding RNAs.

Mol Genet Genomics 2016 Jun 17;291(3):1013-33. Epub 2016 Feb 17.

Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, The Second Xiangya Hospital, Central South University, #139 Renmin Middle Road, Changsha, 410011, Hunan, China.

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http://dx.doi.org/10.1007/s00438-016-1179-yDOI Listing
June 2016

Critical Link Between Epigenetics and Transcription Factors in the Induction of Autoimmunity: a Comprehensive Review.

Clin Rev Allergy Immunol 2016 Jun;50(3):333-44

Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1007/s12016-016-8534-yDOI Listing
June 2016

Roles of transcription factors and epigenetic modifications in differentiation and maintenance of regulatory T cells.

Microbes Infect 2016 Jun 9;18(6):378-386. Epub 2016 Mar 9.

Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2016.02.004DOI Listing
June 2016

The Inflammatory Response in Psoriasis: a Comprehensive Review.

Clin Rev Allergy Immunol 2016 Jun;50(3):377-89

Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1007/s12016-016-8535-xDOI Listing
June 2016

The Bach Family of Transcription Factors: A Comprehensive Review.

Clin Rev Allergy Immunol 2016 Jun;50(3):345-56

Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1007/s12016-016-8538-7DOI Listing
June 2016

High salt promotes autoimmunity by TET2-induced DNA demethylation and driving the differentiation of Tfh cells.

Sci Rep 2016 06 21;6:28065. Epub 2016 Jun 21.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

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http://dx.doi.org/10.1038/srep28065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914849PMC
June 2016

Interleukin-17 in systemic lupus erythematosus: A comprehensive review.

Autoimmunity 2015 20;48(6):353-61. Epub 2015 Apr 20.

a Department of Dermatology , Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics , Changsha , China .

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http://dx.doi.org/10.3109/08916934.2015.1037441DOI Listing
May 2016

Extracellular vesicle microRNAs: biomarker discovery in various diseases based on RT-qPCR.

Authors:
Ying Liu Qianjin Lu

Biomark Med 2015 ;9(8):791-805

Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, Second Xiangya Hospital, Central South University, #139 Renmin Middle Rd, Changsha, Hunan 410011, PR China.

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http://dx.doi.org/10.2217/BMM.15.45DOI Listing
May 2016

Some like it hot: The emerging role of spicy food (capsaicin) in autoimmune diseases.

Autoimmun Rev 2016 May 23;15(5):451-6. Epub 2016 Jan 23.

Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S15689972163000
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http://dx.doi.org/10.1016/j.autrev.2016.01.009DOI Listing
May 2016

Increased 5-hydroxymethylcytosine in CD4(+) T cells in systemic lupus erythematosus.

J Autoimmun 2016 May 13;69:64-73. Epub 2016 Mar 13.

Department of Dermatology, The Second Xiangya Hospital of Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.03.001DOI Listing
May 2016

Eosinophilic Skin Diseases: A Comprehensive Review.

Clin Rev Allergy Immunol 2016 Apr;50(2):189-213

Department of Dermatology, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan, 410011, China.

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http://dx.doi.org/10.1007/s12016-015-8485-8DOI Listing
April 2016

The Eosinophil in Health and Disease: from Bench to Bedside and Back.

Clin Rev Allergy Immunol 2016 Apr;50(2):125-39

Hunan Key Laboratory of Medical Epigenomics & Department of Dermatology, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan, 410011, China.

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http://dx.doi.org/10.1007/s12016-015-8507-6DOI Listing
April 2016

Old lines tell new tales: Blaschko linear lupus erythematosis.

Autoimmun Rev 2016 Apr 9;15(4):291-306. Epub 2015 Dec 9.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2015.11.014DOI Listing
April 2016

CSTMP Exerts Anti-Inflammatory Effects on LPS-Induced Human Renal Proximal Tubular Epithelial Cells by Inhibiting TLR4-Mediated NF-κB Pathways.

Inflammation 2016 Apr;39(2):849-59

Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha, 410000, China.

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http://dx.doi.org/10.1007/s10753-016-0315-5DOI Listing
April 2016

A Player and Coordinator: The Versatile Roles of Eosinophils in the Immune System.

Transfus Med Hemother 2016 Mar 18;43(2):96-108. Epub 2016 Mar 18.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, China.

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http://dx.doi.org/10.1159/000445215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872051PMC
March 2016

CD24: from a Hematopoietic Differentiation Antigen to a Genetic Risk Factor for Multiple Autoimmune Diseases.

Clin Rev Allergy Immunol 2016 Feb;50(1):70-83

Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenetics, Central South University, #139 Renmin Middle Rd, Changsha, Hunan, 410011, People's Republic of China.

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http://dx.doi.org/10.1007/s12016-015-8470-2DOI Listing
February 2016

TET Family of Dioxygenases: Crucial Roles and Underlying Mechanisms.

Cytogenet Genome Res 2015 21;146(3):171-80. Epub 2015 Aug 21.

Department of Dermatology, Hunan Key Laboratory of Medical Epigenomics, Second Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.1159/000438853DOI Listing
January 2016

The role of icaritin in regulating Foxp3/IL17a balance in systemic lupus erythematosus and its effects on the treatment of MRL/lpr mice.

Clin Immunol 2016 Jan 18;162:74-83. Epub 2015 Nov 18.

Department of Dermatology and Epigenetic Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.11.006DOI Listing
January 2016

Genome-wide profiling of DNA methylation and gene expression in esophageal squamous cell carcinoma.

Oncotarget 2016 Jan;7(4):4507-21

Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.6607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826222PMC
January 2016

Overexpression of JMJD3 may contribute to demethylation of H3K27me3 in CD4+ T cells from patients with systemic sclerosis.

Clin Immunol 2015 Dec 17;161(2):396-9. Epub 2015 Mar 17.

Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.03.006DOI Listing
December 2015

Cutaneous nodules with positive autoantibodies: histoid leprosy.

Lancet 2015 Nov;386(10006):1915-6

Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(15)00678-9DOI Listing
November 2015

Epigenetic dynamics in immunity and autoimmunity.

Int J Biochem Cell Biol 2015 Oct 27;67:65-74. Epub 2015 May 27.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha 410011, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2015.05.022DOI Listing
October 2015

Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis.

Int J Biochem Cell Biol 2015 Oct 1;67:92-100. Epub 2015 Jun 1.

Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2015.05.023DOI Listing
October 2015

Primary cutaneous CD4+ small-to-medium-sized pleomorphic T-cell lymphoma: a rare case report of infant.

J Clin Pathol 2015 Oct 25;68(10):855-8. Epub 2015 Jun 25.

Department of Dermatology, Second Xiangya Hospital, Central South University; Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China.

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http://dx.doi.org/10.1136/jclinpath-2015-203113DOI Listing
October 2015

Peripheral whole blood FOXP3 TSDR methylation: a potential marker in severity assessment of autoimmune diseases and chronic infections.

Immunol Invest 2015 1;44(2):126-36. Epub 2014 Aug 1.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics , Changsha, Hunan , PR China .

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http://dx.doi.org/10.3109/08820139.2014.938165DOI Listing
September 2015

Increased expression of TLR2 in CD4(+) T cells from SLE patients enhances immune reactivity and promotes IL-17 expression through histone modifications.

Eur J Immunol 2015 Sep 26;45(9):2683-93. Epub 2015 Jun 26.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, P. R. China.

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http://dx.doi.org/10.1002/eji.201445219DOI Listing
September 2015

Lupus: The Immunological Impact of Altered DNA Methylation.

Authors:
Qianjin Lu

J Investig Dermatol Symp Proc 2015 Jul;17(1):26-8

Department of dermatology, The 2nd Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, People's Republic of China.

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http://dx.doi.org/10.1038/jidsymp.2015.4DOI Listing
July 2015

DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis.

Clin Epigenetics 2015 7;7:61. Epub 2015 Jul 7.

Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Suite 6510, Davis, CA 95616 USA.

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http://dx.doi.org/10.1186/s13148-015-0098-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491885PMC
July 2015

The effect of mycophenolic acid on epigenetic modifications in lupus CD4+T cells.

Clin Immunol 2015 May 17;158(1):67-76. Epub 2015 Mar 17.

Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.03.005DOI Listing
May 2015

The real culprit in systemic lupus erythematosus: abnormal epigenetic regulation.

Int J Mol Sci 2015 May 15;16(5):11013-33. Epub 2015 May 15.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha 410011, China.

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http://dx.doi.org/10.3390/ijms160511013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463688PMC
May 2015

The role of microRNA-1246 in the regulation of B cell activation and the pathogenesis of systemic lupus erythematosus.

Clin Epigenetics 2015 14;7:24. Epub 2015 Mar 14.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan 410011 China.

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http://dx.doi.org/10.1186/s13148-015-0063-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364674PMC
March 2015

The emerging role of circulating microRNAs as biomarkers in autoimmune diseases.

Autoimmunity 2014 Nov 23;47(7):419-29. Epub 2014 Jun 23.

Department of Dermatology, The 2nd Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics , Changsha , China .

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http://dx.doi.org/10.3109/08916934.2014.929667DOI Listing
November 2014

DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype.

J Autoimmun 2014 Nov 3;54:127-36. Epub 2014 Aug 3.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2014.07.002DOI Listing
November 2014

Epigenetics in the treatment of systemic lupus erythematosus: potential clinical application.

Clin Immunol 2014 Nov 16;155(1):79-90. Epub 2014 Sep 16.

Department of Dermatology and Epigenetic Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2014.09.002DOI Listing
November 2014

Hypomethylation and overexpression of ITGAL (CD11a) in CD4(+) T cells in systemic sclerosis.

Clin Epigenetics 2014 11;6(1):25. Epub 2014 Nov 11.

Department of Dermatology, Second Xiangya Hospital, Central South University, 139 Ren-Min Road, Changsha, 410011 China.

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http://dx.doi.org/10.1186/1868-7083-6-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237764PMC
November 2014

Rapidly progressing leg ulcer with fever in a woman with chronic diarrhea.

JAMA 2014 Nov;312(20):2158-9

Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China.

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http://dx.doi.org/10.1001/jama.2014.13007DOI Listing
November 2014

The mechanisms and applications of T cell vaccination for autoimmune diseases: a comprehensive review.

Clin Rev Allergy Immunol 2014 Oct;47(2):219-33

Hunan Key Laboratory of Medical Epigenetics, Department of Dermatology, Second Xiangya Hospital, Central South University, #139 Renmin Middle Rd, Changsha, 410011, Hunan, People's Republic of China.

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http://dx.doi.org/10.1007/s12016-014-8439-6DOI Listing
October 2014