Dr. Qiang Chen, PhD - Arizona State University - Professor

Dr. Qiang Chen

PhD

Arizona State University

Professor

United States

Dr. Qiang Chen, PhD - Arizona State University - Professor

Dr. Qiang Chen

PhD

Introduction

Primary Affiliation: Arizona State University - United States

Publications

26Publications

488Reads

-Profile Views

666PubMed Central Citations

Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus.

PLoS One 2014 27;9(3):e93541. Epub 2014 Mar 27.

The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America; College of Technology and Innovation, Arizona State University, Mesa, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093541PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968140PMC
May 2015
13 Reads
13 Citations
3.234 Impact Factor

Plant-made biologics.

Biomed Res Int 2014 2;2014:418064. Epub 2014 Jun 2.

Department of Biological Systems Engineering, Virginia Tech, Blacksburg, Virginia, VA 24061, USA.

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http://dx.doi.org/10.1155/2014/418064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060392PMC
February 2015
11 Reads
1 Citation

A plant-produced antigen elicits potent immune responses against West Nile virus in mice.

Biomed Res Int 2014 3;2014:952865. Epub 2014 Apr 3.

The Biodesign Institute, Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287, USA ; School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1155/2014/952865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996298PMC
January 2015
15 Reads
11 Citations

Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants.

Plant Biotechnol J 2014 Oct 29;12(8):1098-107. Epub 2014 Jun 29.

The Biodesign Institute, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1111/pbi.12217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175135PMC
October 2014
21 Reads
16 Citations
5.752 Impact Factor

Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins.

J Vis Exp 2013 Jul 23(77). Epub 2013 Jul 23.

The College of Technology and Innovation, Center for Infectious Disease and Vaccinology, The Biodesign Institute, Arizona State University, Arizona, USA.

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http://dx.doi.org/10.3791/50521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846102PMC
July 2013
37 Reads
39 Citations

Plant-derived virus-like particles as vaccines.

Hum Vaccin Immunother 2013 Jan 20;9(1):26-49. Epub 2012 Sep 20.

Center for Infectious Diseases and Vaccinology, Biodesign Institute at Arizona State University, Tempe, AZ USA.

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http://dx.doi.org/10.4161/hv.22218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667944PMC
January 2013
14 Reads
20 Citations
2.131 Impact Factor

A novel system for rapid and cost-effective production of detection and diagnostic reagents of West Nile virus in plants.

J Biomed Biotechnol 2012 4;2012:106783. Epub 2011 Dec 4.

The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1155/2012/106783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236498PMC
May 2012
9 Reads
15 Citations
3.170 Impact Factor

Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations.

Plant Cell Rep 2012 Mar 2;31(3):573-84. Epub 2011 Dec 2.

The Center for Infectious Diseases and Vaccinology, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1007/s00299-011-1196-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278561PMC
March 2012
5 Reads
26 Citations
3.071 Impact Factor

Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce.

Plant Biotechnol J 2012 Jan 26;10(1):95-104. Epub 2011 Aug 26.

The Biodesign Institute and College of Technology and Innovation, Arizona State University, Tempe, AZ, USA.

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http://dx.doi.org/10.1111/j.1467-7652.2011.00649.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232331PMC
January 2012
14 Reads
28 Citations
5.752 Impact Factor

A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge.

Proc Natl Acad Sci U S A 2011 Dec 5;108(51):20695-700. Epub 2011 Dec 5.

Center of Infectious Disease and Vaccinology, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1073/pnas.1117715108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251076PMC
December 2011
23 Reads
23 Citations
9.810 Impact Factor

Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana.

Plant Biotechnol J 2011 Sep 1;9(7):807-16. Epub 2011 Feb 1.

Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1111/j.1467-7652.2011.00593.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022790PMC
September 2011
8 Reads
29 Citations
5.752 Impact Factor

Geminiviral vectors based on bean yellow dwarf virus for production of vaccine antigens and monoclonal antibodies in plants.

Hum Vaccin 2011 Mar 1;7(3):331-8. Epub 2011 Mar 1.

The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, AZ, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166492PMC
http://dx.doi.org/10.4161/hv.7.3.14262DOI Listing
March 2011
45 Reads
31 Citations
3.643 Impact Factor

High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system.

Biotechnol Bioeng 2010 May;106(1):9-17

The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona 85287-4501, USA.

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http://dx.doi.org/10.1002/bit.22652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905544PMC
May 2010
26 Reads
49 Citations
4.130 Impact Factor

Norwalk virus-like particles as vaccines.

Expert Rev Vaccines 2010 Mar;9(3):299-307

Center for Infectious Diseases and Vaccinology, Biodesign Institute at Arizona State University, Tempe, AZ 85287, USA and Dept of Basic Medical Sciences, The University of Arizona College of Medicine-Phoenix in Partnership with Arizona State University, Phoenix, AZ 85004, USA.

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http://dx.doi.org/10.1586/erv.09.163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862602PMC
March 2010
31 Reads
32 Citations
4.210 Impact Factor

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice.

Proc Natl Acad Sci U S A 2010 Feb 1;107(6):2419-24. Epub 2010 Feb 1.

The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1073/pnas.0914503107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823901PMC
February 2010
20 Reads
28 Citations
9.810 Impact Factor

A DNA replicon system for rapid high-level production of virus-like particles in plants.

Biotechnol Bioeng 2009 Jul;103(4):706-14

Biodesign Institute, School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1002/bit.22299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704498PMC
July 2009
8 Reads
48 Citations
4.130 Impact Factor

Viral vectors for production of recombinant proteins in plants.

J Cell Physiol 2008 Aug;216(2):366-77

UTS BIOTEC, Section of Genetics and Plant Genomics, ENEA CR Casaccia, Rome, Italy.

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http://dx.doi.org/10.1002/jcp.21423DOI Listing
August 2008
23 Reads
42 Citations
3.840 Impact Factor

An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles.

Vaccine 2008 Mar 15;26(15):1846-54. Epub 2008 Feb 15.

The Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, AZ 85287-5401, USA.

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http://dx.doi.org/10.1016/j.vaccine.2008.01.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744496PMC
March 2008
7 Reads
47 Citations
3.624 Impact Factor

Isolation and characterization of glutamine synthetase genes in Chlamydomonas reinhardtii.

Authors:
Q Chen C D Silflow

Plant Physiol 1996 Nov;112(3):987-96

Department of Genetics and Cell Biology, University of Minnesota, St. Paul 55108, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC158025PMC
http://dx.doi.org/10.1104/pp.112.3.987DOI Listing
November 1996
4 Reads
8 Citations
6.841 Impact Factor

A 21-kDa chloroplast heat shock protein assembles into high molecular weight complexes in vivo and in Organelle.

J Biol Chem 1994 May;269(18):13216-23

Department of Biochemistry, University of Arizona, Tucson 85721.

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May 1994
3 Reads
9 Citations
4.573 Impact Factor

Analysis of conserved domains identifies a unique structural feature of a chloroplast heat shock protein.

Authors:
Q Chen E Vierling

Mol Gen Genet 1991 Aug;228(1-2):328

Department of Biochemistry, University of Arizona, Tucson 85721.

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August 1991
5 Reads
1 Citation

Analysis of conserved domains identifies a unique structural feature of a chloroplast heat shock protein.

Authors:
Q Chen E Vierling

Mol Gen Genet 1991 May;226(3):425-31

Department of Biochemistry, University of Arizona, Tucson 85721.

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http://dx.doi.org/10.1007/bf00260655DOI Listing
May 1991
11 Reads
23 Citations

Accumulation, stability, and localization of a major chloroplast heat-shock protein.

J Cell Biol 1990 Jun;110(6):1873-83

Department of Biochemistry, University of Arizona, Tucson 85721.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116130PMC
http://dx.doi.org/10.1083/jcb.110.6.1873DOI Listing
June 1990
4 Reads
22 Citations
9.834 Impact Factor

The major low-molecular-weight heat shock protein in chloroplasts shows antigenic conservation among diverse higher plant species.

Mol Cell Biol 1989 Feb;9(2):461-8

Department of Biochemistry, University of Arizona, Tucson 85721.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC362621PMC
http://dx.doi.org/10.1128/mcb.9.2.461DOI Listing
February 1989
5 Reads
11 Citations
4.780 Impact Factor