Mr Prince Adoba, Bachelor's degree - Kwame Nkrumah University of Science and Technology - Mr

Mr Prince Adoba

Bachelor's degree

Kwame Nkrumah University of Science and Technology

Mr

Cape Coast, Central | Ghana

Main Specialties: Biology

Additional Specialties: Biomedical Research

ORCID logohttps://orcid.org/0000-0002-8291-1371

Mr Prince Adoba, Bachelor's degree - Kwame Nkrumah University of Science and Technology - Mr

Mr Prince Adoba

Bachelor's degree

Introduction

Primary Affiliation: Kwame Nkrumah University of Science and Technology - Cape Coast, Central , Ghana

Specialties:

Additional Specialties:

Education

Sep 2016
Kwame Nkrumah University of Science and Technology
Chemical Pathology
Molecular Medicine

Experience

Aug 2015
Trauma and Specialist Hospital
Medical Laboratory Scientist
Laboratory

Publications

15Publications

128Reads

84Profile Views

7PubMed Central Citations

High Iodine Deficiency among Pregnant Women in Periurban Ghana: A Hospital-Based Longitudinal Study.

J Nutr Metab 2018 3;2018:9706805. Epub 2018 Jun 3.

Department of Medical Laboratory Science, University of Cape Coast, Cape Coast, Ghana.

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http://dx.doi.org/10.1155/2018/9706805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008623PMC
June 2018
19 Reads

Knowledge Level and Determinants of Neonatal Jaundice: A Cross-Sectional Study in the Effutu Municipality of Ghana.

Int J Pediatr 2018 1;2018:3901505. Epub 2018 Mar 1.

Department of Chemical Pathology, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.

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http://dx.doi.org/10.1155/2018/3901505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852853PMC
March 2018
4 Reads

Chronic kidney disease stages among diabetes patients in the Cape Coast Metropolis.

Saudi J Kidney Dis Transpl 2016 Nov-Dec;27(6):1231-1238

Department of Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

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http://dx.doi.org/10.4103/1319-2442.194658DOI Listing
August 2017
5 Reads

Chronic kidney disease stages among diabetes patients in the Cape Coast Metropolis

Ephraim RK, Arthur E, Owiredu W, Adoba P, Agbodzakey H, Eghan BA. Chronic kidney disease stages amon

Saudi J Kidney Dis Transpl

Diabetes patients worldwide are at a high risk of chronic kidney disease (CKD) which affects their quality of life and increases the risk of early death. This study used the new kidney disease improving global outcomes (KDIGO) guidelines to establish the prevalence and also identify the factors associated with CKD among diabetes patients in the Cape Coast Metropolis. Two hundred (200) diabetes patients were randomly recruited from the diabetic clinic of the Cape Coast Teaching Hospital from January to April 2014. Blood and urine samples were collected for the estimation of serum creatinine and urine protein, respectively. The estimated glomerular filtration rate (eGFR) was calculated using the chronic kidney disease epidemiology collaboration (CKD-EPI) equation; the 2012 KDIGO guidelines was used to assess CKD. Based on these guidelines, 37% of our participants had CKD. Sixteen percent (16%) of the participants had Stage 1 CKD and 17% had an eGFR <60 mL/min/1.73 m 2 . Albuminuria was higher among female diabetic patients compared to males (69.2% vs. 30.8%, P = 0.017). CKD was present in participants on oral hypoglycemic agents (OHAs) alone or both OHA and insulin. Duration of diabetes, systolic blood pressure, older age, and use of OHA were associated with CKD (P <0.05).

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November 2016
5 Reads

Normal Non-HDL Cholesterol, Low Total Cholesterol, and HDL Cholesterol Levels in Sickle Cell Disease Patients in the Steady State: A Case-Control Study of Tema Metropolis

Journal of Lipids, vol. 2016, Article ID 7650530, 5 pages, 2016. doi:10.1155/2016/7650530

Journal of Lipids

Background. Abnormal lipid homeostasis in sickle cell disease (SCD) is characterized by defects in plasma and erythrocyte lipids and may increase the risk of cardiovascular disease. This study assessed the lipid profile and non-HDL cholesterol level of SCD patients. Methods. A hospital-based cross-sectional study was conducted in 50 SCD patients, in the steady state, aged 8–28 years, attending the SCD clinic, and 50 healthy volunteers between the ages of 8–38 years. Serum lipids were determined by enzymatic methods and non-HDL cholesterol calculated by this formula: non-HDL-C = TC-HDL-C. Results. Total cholesterol (TC) () and high-density lipoprotein cholesterol (HDL-C) () were significantly decreased in cases compared to controls. The levels of non-HDL-C, low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) were similar among the participants. The levels of decrease in TC and HDL were associated with whether a patient was SCD-SS or SCD-SC. Systolic blood pressure and diastolic blood pressure were each significantly associated with increased VLDL [SBP, , OR: 0.74 (CI: 0.6–0.93); DBP, , OR: 1.45 (CI: 1.05–2.0)]. Conclusion. Dyslipidemia is common among participants in this study. It was more pronounced in the SCD-SS than in SCD-SC. This dyslipidemia was associated with high VLDL as well as increased SBP and DBP.

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November 2016
6 Reads

Assessment of the RIFLE criteria for the diagnosis of Acute Kidney Injury; a retrospective study in South-Western Ghana.

BMC Nephrol 2016 07 26;17(1):99. Epub 2016 Jul 26.

Department of Medical Laboratory Technology, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.

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http://dx.doi.org/10.1186/s12882-016-0318-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962492PMC
July 2016
5 Reads
1 Citation
1.520 Impact Factor

Prevalence of chronic kidney disease among the high risk population in South-Western Ghana; a cross sectional study.

Can J Kidney Health Dis 2015 3;2:40. Epub 2015 Nov 3.

Department of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

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http://dx.doi.org/10.1186/s40697-015-0076-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630826PMC
November 2015
12 Reads
1 Citation

High prevalence of hepatitis B and poor knowledge on hepatitis B and C viral infections among barbers: a cross-sectional study of the Obuasi municipality, Ghana.

BMC Public Health 2015 Oct 11;15:1041. Epub 2015 Oct 11.

Department of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

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http://dx.doi.org/10.1186/s12889-015-2389-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601136PMC
October 2015
18 Reads
1 Citation
2.264 Impact Factor

Chronic kidney disease is common in sickle cell disease: a cross-sectional study in the Tema Metropolis, Ghana.

BMC Nephrol 2015 May 29;16:75. Epub 2015 May 29.

Medical Laboratory Division, Department of Medical Laboratory Technology, UCC, Cape Coast, Ghana.

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http://dx.doi.org/10.1186/s12882-015-0072-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448314PMC
May 2015
30 Reads
4 Citations
1.520 Impact Factor

Chronic kidney disease is common in sickle cell disease: a cross-sectional study in the Tema Metropolis, Ghana

BMC Nephrology 2015, 16:75

BMC Nephrology

Background Renal involvement in sickle cell disease (SCD) contributes significantly to morbidity and mortality. The aim of this study was to determine the prevalence of chronic kidney disease (CKD) amongst SCD patients, and how basic clinical variables differ across haemoglobin genotypes. Methods A hospital-based cross-sectional study conducted from December 2013 to May 2014 at the Sickle cell clinic of the Tema General Hospital. One hundred and ninety-four (194) participants with SCD, receiving medical care at the outpatient sickle cell clinic were enrolled onto the study. A structured questionnaire was administered to obtain information on demography, clinical history, blood pressure and anthropometry. Blood and urine samples were taken for serum creatinine and proteinuria determination respectively. The estimated GFR (eGFR) was calculated using the CKD-EPI and Schwartz equations. CKD was defined according to the Kidney Disease Improving Global Outcomes (KDIGO) guidelines. Analysis was performed using GraphPad prism and P <0.05 was considered statistically significant. Results CKD was present in 39.2 % of participants. Using KDIGO guidelines, 40.8 % of the HbSS participants had stage 1 CKD and none had stage 2 CKD. In addition, 30.8 % of the HbSC participants had stage 1 CKD and 3.8 % had stage 2 CKD. There was a trend of increasing age across CKD stages and stage 2 CKD participants were oldest (P < 0.001). Conclusion Results from the current study suggest that CKD is common amongst SCD patients and prevalence and intensity increases with age. Proteinuria and CKD was more common in HbSS genotype than in HbSC genotype.

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May 2015
3 Reads

Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study.

Niger Med J 2014 Nov;55(6):504-7

Department of Laboratory Technology, Medical Laboratory Division, University of Cape Coast, Cape Coast, Ghana.

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http://dx.doi.org/10.4103/0300-1652.144709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262849PMC
November 2014
3 Reads

Seroprevalence of Hepatitis B and C Viral Infections among Type 2 Diabetics: A Cross-sectional Study in the Cape Coast Metropolis

Ann Med Health Sci Res. 2014 Sep;4(5):719-22

Annals of Medical and Health Science Research

BACKGROUND: Type 2 diabetes comes with various complications and this may be compounded by morbidities of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. AIMS: This study examined the prevalence of HBV and HCV infectionst among type 2 diabetics as well as its associated factors. This randomized cross-sectional study was conducted at the Diabetic Clinic of the Central Regional Hospital, Cape Coast between December 2012 and April 2013. SUBJECTS AND METHODS: A well-structured questionnaire was used to recruit 110 type 2 diabetics. Venous blood samples were collected for the estimation of blood glucose and to screen for HBV and HCV infections. Data analysis was carried out using SPSS Version 17.0. Descriptive analysis was performed and results expressed as means (SD) and n (%). P < 0.05 was considered significant. RESULTS: Prevalence of HBV in type 2 diabetics was 5.5% (6/110). No type 2 diabetic was positive for HCV. The prevalence of HBV infection in the type 2 diabetes mellitus (T2DM) participants was higher (5.5% [6/110]) than that of HCV (0/110). A total of 69.1% (76/110) T2DM patients had poor glycemic control. Mean waist and hip circumference was higher among HBV-negative T2DM participants (99.3; 106.9) than HBV-positive participants (87.2; 101.8). CONCLUSIONS: The seroprevalence of HBV was higher than that of HCV in T2DM patients. T2DM patients would require necessary preventive measures like prophylaxis, to reduce the risk of HBV infection and its ramifications.

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September 2014
5 Reads

Top co-authors

Hope Agbodzakey
Hope Agbodzakey

Medical Laboratory Division

6
Patrick Adu
Patrick Adu

University of Cape Coast

4
Samuel Asamoah Sakyi
Samuel Asamoah Sakyi

School of Medical Science

3
Samuel A Sakyi
Samuel A Sakyi

School of Medical Sciences

2
Stephen Kyei Boadu
Stephen Kyei Boadu

University of Cape Coast

1