Prem Pais

Prem Pais

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Impact of blood pressure lowering, cholesterol lowering and their combination in Asians and non-Asians in those without cardiovascular disease: an analysis of the HOPE 3 study.

Eur J Prev Cardiol 2019 May 11;26(7):681-697. Epub 2018 Dec 11.

2 Population Health Research Institute, McMaster University and Hamilton Health Sciences, Canada.

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http://dx.doi.org/10.1177/2047487318819019DOI Listing
May 2019

Treadmill stress tests should not be part of "routine health check package".

Authors:
Prem Pais

Indian Heart J 2018 Nov - Dec;70(6):934-936. Epub 2018 Oct 12.

Professor St. John's Research Institute, Consultant Physician, Manipal Hospital Bengaluru, India. Electronic address:

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http://dx.doi.org/10.1016/j.ihj.2018.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306354PMC
January 2019

Technique of blood pressure measurement.

Authors:
Prem Pais

Natl Med J India 1990 Nov-Dec;3(6):294-296

St John's Medical College Hospital, Bangalore 560034, India.

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June 2018

Anti-Inflammatory Therapy With Canakinumab for the Prevention and Management of Diabetes.

J Am Coll Cardiol 2018 05 12;71(21):2392-2401. Epub 2018 Mar 12.

Center for Cardiovascular Disease Prevention, Harvard Medical School, Boston, Massachusetts; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2018.03.002DOI Listing
May 2018

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.

N Engl J Med 2017 09 27;377(12):1119-1131. Epub 2017 Aug 27.

From the Center for Cardiovascular Disease Prevention (P.M.R., B.M.E., J.G.M., R.J.G.) and the Cardiovascular Division (P.M.R., B.M.E., P.L.), Brigham and Women's Hospital, Harvard Medical School, Boston; Novartis, East Hanover, NJ, and Basel, Switzerland (T.T., W.H.C.); Baylor College of Medicine, Houston (C.B.); Federal University of São Paulo (F.F.) and the Heart Institute (InCor), University of São Paulo Medical School (J.N.), São Paulo, and Faculdade Evangelica de Medicina do Parana, Curitiba (P.R.F.R.) - all in Brazil; Deutsches Herzzentrum München, Technische Universität München, German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, Munich (W.K.), and the Department of Cardiology and Berlin-Brandenburg Center for Regenerative Therapies, Charité Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin (S.D.A.) - both in Germany; Academic Medical Center of the University of Amsterdam, Amsterdam (J.J.P.K.), Alkmaar Medical Center, Alkmaar (J.H.C.), and VieCuri Medical Center for Northern Limburg, Venlo (R.P.T.T.) - all in the Netherlands; Manipal Hospital, St. John's Research Institute, Bangalore, India (P.P.); Pavol Jozef Safarik University, Kosice, Slovakia (D.P.); McGill University, Montreal (J.G.); First Faculty of Medicine and Thomayer Hospital, Prague, Czech Republic (R.C.); Cordoba Hospital, Cordoba, Argentina (A.L.); University of Szeged, Szeged, Hungary (T.F.); City Hospital No. 64, Medical Institute RUDN University, Moscow (Z.K.); Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania (L.V.-S.); University of East Anglia, Norwich Medical School, Norwich, United Kingdom (M.F.); Tohoku University Hospital, Sendai (H.S.), and National Cerebral and Cardiovascular Center, Osaka (H.O.) - both in Japan; and Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden (M.D.).

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http://dx.doi.org/10.1056/NEJMoa1707914DOI Listing
September 2017

Commercial conflict of interest and medical publication: What should the practising physician do about it?

Authors:
Prem Pais

Indian J Med Ethics 2016 Oct-Dec;1(4):227-228. Epub 2016 Sep 14.

Professor, St John's Research Institute, Division of Clinical Research and Training, and Consultant Physician, Manipal Hospital, Bangalore, India,.

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http://dx.doi.org/10.20529/IJME.2016.066DOI Listing
August 2017

Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease.

N Engl J Med 2016 May 2;374(21):2032-43. Epub 2016 Apr 2.

From the Population Health Research Institute, Hamilton Health Sciences (S.Y., E.L., J.B., R.M., J.P., H.J.), Department of Medicine (S.Y., E.L., R.M.), School of Rehabilitation Science (J.B.), Department of Clinical Epidemiology and Biostatistics (J.P.), McMaster University, Hamilton, ON, Li Ka Shing Knowledge Institute and Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.), and Institut Universitaire de Cardiologie et Pneumologie de Québec, Université Laval, Quebec, QC (G.D.) - all in Canada; St. John's Research Institute (P.P., D.X.), and St. John's Medical College (D.X.), Bangalore, India; Fundacion Oftalmológica de Santander and Instituto Masira, Medical School, Universidad de Santander, Bucaramanga (P.L.-J.), and Universidad del Norte, Barranquilla (J.L.A.) - both in Colombia; Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z., L.L.); Dante Pazzanese Institute of Cardiology (A.A.) and HCor-Heart Hospital (L.S.P.), Sao Paulo; Institute of Cardiology, Kiev, Ukraine (A.P.); Hungarian Institute of Cardiology, Semmelweis University, Budapest, Hungary (M.K., K. Keltai); Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, University of Cape Town, Soweto Cardiovascular Research Group, Cape Town, South Africa (K.S.); Institute of Clinical Cardiology in the Russian Cardiology Research Complex, Moscow (I.C.); the Department of Cardiology, Academic Medical Center, Amsterdam (R.J.G.P.); the Department of Medical Sciences, Cardiology, Clinical Research Center, Uppsala University, Uppsala, Sweden (C.H.); Universiti Teknologi Majlis Amansh Rakyat, Selayang, and University College Sedaya International University, Kuala Lumpur (K.Y.) - both in Malaysia; Lady Davis Carmel Medical Center, Ruth and Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel (B.S.L.); University Hospital Motol, Prague, Czech Repu

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http://dx.doi.org/10.1056/NEJMoa1600177DOI Listing
May 2016

Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease.

N Engl J Med 2016 May 2;374(21):2021-31. Epub 2016 Apr 2.

From the Population Health Research Institute, Hamilton Health Sciences (S.Y., J.B., R.M., J.P., H.J., P.G., E.L.), Departments of Medicine (S.Y., R.M., E.L.) and Clinical Epidemiology and Biostatistics (J.P.), and School of Rehabilitation Science (J.B.), McMaster University, Hamilton, ON, Institut Universitaire de Cardiologie et Pneumologie de Québec, Université Laval, Quebec, QC (G.D.), and Li Ka Shing Knowledge Institute and Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.) - all in Canada; Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z., L.L.); St. John's Medical College (D.X.) and St. John's Research Institute (D.X., P.P.), Bangalore, India; Fundacion Oftalmológica de Santander and Instituto Masira, Medical School, Universidad de Santander, Bucaramanga (P.L.-J.), and University of Quindio, Armenia (G.S.-V.) - both in Colombia; College of Medicine, University of the Philippines, Manila (A.D.); Dante Pazzanese Institute of Cardiology (A.A.) and HCor-Heart Hospital (L.S.P.), São Paulo; Institute of Cardiology, Kiev, Ukraine (A.P.); Hungarian Institute of Cardiology, Semmelweis University, Budapest (K. Keltai, M.K.); Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, University of Cape Town, Soweto Cardiovascular Research Group, Cape Town, South Africa (K.S.); Department of Cardiology, Academic Medical Center, Amsterdam (R.J.G.P); Department of Medical Sciences, Cardiology, Clinical Research Center, Uppsala University, Uppsala, Sweden (C.H.); Institute of Clinical Cardiology in the Russian Cardiology Research Complex, Moscow (I.C.); Universiti Teknologi Majlis Amansh Rakyat, Selayang, and University College Sedaya International University, Kuala Lumpur - both in Malaysia (K.Y.); Lady Davis Carmel Medical Center, Ruth and Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa (B.S.L.); Universi

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http://dx.doi.org/10.1056/NEJMoa1600176DOI Listing
May 2016

Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease.

N Engl J Med 2016 May 2;374(21):2009-20. Epub 2016 Apr 2.

From the Population Health Research Institute, Hamilton Health Sciences (E.M.L., J.B., R.M., J.P., J.W., H.J., S.Y.), the Department of Medicine (E.M.L., R.M., S.Y.), the School of Rehabilitation Science (J.B.), and the Department of Clinical Epidemiology and Biostatistics (J.P.), McMaster University, Hamilton, ON, Li Ka Shing Knowledge Institute and Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.), and Institut Universitaire de Cardiologie et Pneumologie de Québec, Université Laval, Quebec, QC (G.D.) - all in Canada; Fundacion Oftalmológica de Santander and Instituto Masira, Medical School, Universidad de Santander, Bucaramanga (P.L.-J.), and University of Caldas and Institución Prestadora de Salud Internistas de Caldas, Manizales (D.I.M.S.) - both in Colombia; Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.Z., L.L.); St. John's Research Institute (P.P., D.X.) and St. John's Medical College (D.X.), Bangalore, India; Instituto Cardiovascular de Rosario, Rosario, Argentina (R.D.); Hatter Institute for Cardiovascular Research in Africa, Department of Medicine, University of Cape Town, Soweto Cardiovascular Research Group, Cape Town, South Africa (K.S.); College of Medicine, University of the Philippines, Manila (A.D.); Dante Pazzanese Institute of Cardiology (A.A.) and HCor-Heart Hospital (L.S.P.) - both in São Paulo; Hungarian Institute of Cardiology, Semmelweis University, Budapest, Hungary (K. Keltai, M.K.); Institute of Clinical Cardiology in the Russian Cardiology Research Complex, Moscow (I.C.); the Department of Cardiology, Academic Medical Center, Amsterdam (R.J.G.P.); the Department of Medical Sciences, Cardiology, Clinical Research Center, Uppsala University, Uppsala, Sweden (C.H.); Universiti Teknologi Majlis Amansh Rakyat, Selayang, and University College Sedaya International University, Kuala Lumpur (K.Y.) - both in Malaysia; Lady Davis Ca

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http://dx.doi.org/10.1056/NEJMoa1600175DOI Listing
May 2016

High sensitivity C-reactive protein (hsCRP) & cardiovascular disease: An Indian perspective.

Indian J Med Res 2015 Sep;142(3):261-8

Division of Clinical Research & Training, St. John's Research Institute, St. John's National Academy of Health Sciences, Bengaluru, India.

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http://dx.doi.org/10.4103/0971-5916.166582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669860PMC
September 2015

Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial.

Circulation 2015 Aug 23;132(8):624-32. Epub 2015 Jun 23.

From Research Division, Dante Pazzanese Institute of Cardiology, São Paulo, Brazil (A.A.); Duke Clinical Research Institute, Duke Medicine, Durham, NC (R.D.L., P.J.S., C.B.G., J.H.A.); Universidad de La Frontera, Temuco, Chile (F.L.); Mayo Clinic College of Medicine, Rochester, MN (B.J.G.); Bristol-Myers Squibb, Princeton, NJ (M.H.); St. John's Medical College & Research Institute, Bangalore, India (P.P.); Ankara University School of Medicine, Turkey (C.E.); ECLA Estudios Cardiológicos Latinoamérica, Rosario, Argentina (R.D.); INECO Neurociencias Oroño, Rosario, Santa Fe, Argentina (M.C.B.); Cardiovascular Center Aalst, OLV Hospital, Aalst, Belgium (J.B.); G. d'Annunzio University, Chieti, Italy and Fondazione Toscana G. Monasterio, Pisa, Italy (R.D.C.); Tokai University School of Medicine, Isehara, Japan (S.G.); National Institute of Cardiology, Warsaw, Poland (W.R.); and Fu Wai Hospital, Beijing, China (J.Z.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.014807DOI Listing
August 2015

Reducing Premature Cardiovascular Mortality By 2025: The World Heart Federation Roadmap.

Glob Heart 2015 Jun;10(2):97-8

PHRI, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.gheart.2015.04.002DOI Listing
June 2015

Adapting the World Heart Federation Roadmaps at the National Level: Next Steps and Conclusions.

Glob Heart 2015 Jun;10(2):135-6

PHRI, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.gheart.2015.04.004DOI Listing
June 2015

Patterns of alcohol consumption and myocardial infarction risk: observations from 52 countries in the INTERHEART case-control study.

Circulation 2014 Jul 13;130(5):390-8. Epub 2014 Jun 13.

From the Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada (D.P.L., A.S., K.K.T., S.R., S.S.A., S.Y.); London School of Hygiene and Tropical Medicine, London, UK (M.M.); St. John's Medical College, Bangalore, India (P.P.); and Fu Wai Hospital, Beijing, China (L.L.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.113.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.007627DOI Listing
July 2014

Variations in cause and management of atrial fibrillation in a prospective registry of 15,400 emergency department patients in 46 countries: the RE-LY Atrial Fibrillation Registry.

Circulation 2014 Apr 24;129(15):1568-76. Epub 2014 Jan 24.

Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden (J.O., L.W.); Population Health Research Institute, Hamilton, Ontario, Canada (J.S.H., C.A.M., A.G., J.N., S.J.C., S.Y.); Jefferson Medical College, Wynnewood, PA, and Cardiovascular Research Foundation, New York, NY (M.E.); Department of Medicine, University of Cape Town, Cape Town, South Africa (P.C.); Instituto Dante Pazzanesse de Cardiologia, Sao Paulo, Brazil (A.A.); St. John's Medical College, Bangalore, India (P.P., A.S.); Cardiovascular Institute and Fuwai Hospital, Beijing, China (J.Z., L.L.); University Hospital Motol, Prague, Czech Republic (P.J.); Eduardo Mondlane University, Maputo, Mozambique (A.D.); Boehringer-Ingelheim, Ridgefield, CT (P.A.R.); Semmelweis University, Budapest, Hungary (K.K.); Thoraxcenter, University of Groningen, University Medical Center Groningen, the Netherlands (I.C.V.G.); Dubai Hospital, Dubai Health Authority, Dubai, United Arab Emirates (A.F.Y.); and Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Japan (E.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005451DOI Listing
April 2014

P2Y12 inhibitors in acute coronary syndromes: which and when?

Authors:
Prem Pais

Natl Med J India 2013 Mar-Apr;26(2):84-90

Department of Medicine, Clinical Trials Division, St John's Medical College, Bengaluru 5600334, Karnataka, India,

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December 2013

Physicians and their conscience.

Authors:
Prem Pais

Natl Med J India 2012 Jan-Feb;25(1):54-5

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August 2012

Heart failure in India: an area of darkness.

Natl Med J India 2011 Jan-Feb;24(1):53

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July 2011

The Cochrane Library Oversight Committee.

Cochrane Database Syst Rev 2011 Feb 16(8):ED000021. Epub 2011 Feb 16.

Cochrane Library Oversight Committee.

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http://dx.doi.org/10.1002/14651858.ED000021DOI Listing
February 2011

The polypill in the prevention of cardiovascular diseases: key concepts, current status, challenges, and future directions.

Circulation 2010 Nov;122(20):2078-88

Population Health Research Institute, Hamilton Health Sciences, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.109.873232DOI Listing
November 2010

Clinical judgement & evidence-based medicine: time for reconciliation.

Indian J Med Res 2010 Nov;132:623-6

Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028959PMC
November 2010

Polypharmacotherapy for primary prevention of cardiovascular disease.

Indian Heart J 2008 Mar-Apr;60(2 Suppl B):B29-33

Population Health Research Institute, Department of Medicine, McMaster University, Hamilton, Canada.

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May 2009

Rosiglitazone and cardiovascular disease-recent controversy.

Authors:
Prem Pais

Indian Heart J 2008 May-Jun;60(3):241-4

Clinical Trials Division, St. John's Medical College, Bangalore, India.

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March 2009

The need to test the theories behind the Polypill: rationale behind the Indian Polycap Study.

Nat Clin Pract Cardiovasc Med 2009 Feb 23;6(2):96-7. Epub 2008 Dec 23.

Department of Pharmacology, St John's Medical College, Bangalore, India.

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http://dx.doi.org/10.1038/ncpcardio1438DOI Listing
February 2009

Perspectives on the management of coronary artery disease in India.

Heart 2007 Nov;93(11):1334-8

Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1136/hrt.2007.131193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2016940PMC
November 2007

Preventing ischaemic heart disease in developing countries.

Authors:
Prem Pais

Evid Based Cardiovasc Med 2006 Jun 24;10(2):85-8. Epub 2006 May 24.

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http://dx.doi.org/10.1016/j.ebcm.2006.04.050DOI Listing
June 2006

Correlation of regional cardiovascular disease mortality in India with lifestyle and nutritional factors.

Int J Cardiol 2006 Apr 22;108(3):291-300. Epub 2005 Jun 22.

Department of Medicine, Monilek Hospital and Research Centre, Jawahar Nagar, Jaipur 302004, India.

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http://dx.doi.org/10.1016/j.ijcard.2005.05.044DOI Listing
April 2006

Early intervention and prevention of myocardial infarction.

Authors:
Prem S Pais

J Hypertens Suppl 2006 Apr;24(2):S25-30

St John's Medical College, Bangalore, India.

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http://dx.doi.org/10.1097/01.hjh.0000220100.50272.b0DOI Listing
April 2006

Effects of reviparin, a low-molecular-weight heparin, on mortality, reinfarction, and strokes in patients with acute myocardial infarction presenting with ST-segment elevation.

JAMA 2005 Jan;293(4):427-35

Population Health Research Institute, Hamilton Health Sciences, Hamilton General Hospital and McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1001/jama.293.4.427DOI Listing
January 2005

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study.

Lancet 2004 Sep 11-17;364(9438):937-52

Population Health Research Institute, Hamilton General Hospital, 237 Barton Street East, Hamilton, Ontario, Canada L8L 2X2.

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http://dx.doi.org/10.1016/S0140-6736(04)17018-9DOI Listing
September 2004