Dr Pratik Tripathi, MD, PhD - Tongji Hospital, Tongji Medical College, - Dr.

Dr Pratik Tripathi

MD, PhD

Tongji Hospital, Tongji Medical College,

Dr.

Wuhan, Hubei | China

Main Specialties: Abdominal Radiology, Cardiothoracic Radiology, Gastroenterology, Muscoskeletal Radiology, Nuclear Medicine, Nuclear Radiology, Radiology-Diagnostic

Additional Specialties: Abdominal Radiology

ORCID logohttps://orcid.org/0000-0002-4291-2118

Dr Pratik Tripathi, MD, PhD - Tongji Hospital, Tongji Medical College, - Dr.

Dr Pratik Tripathi

MD, PhD

Introduction

Primary Affiliation: Tongji Hospital, Tongji Medical College, - Wuhan, Hubei , China

Specialties:

Additional Specialties:

Research Interests:

Education

Sep 2018
Tongji Medical College, HUST
PhD in Radiology and Nuclear Medicine
Sep 2014
Fudan University
MD in Radiology and Nuclear Medicine
Sep 2009
Fudan University
MBBS

Experience

Jan 2018
Tongji Medical College, HUST
PhD
Jul 2017
Hanyang Hospital, Wuhan University of Science and Technology
Clinical Rotation
Feb 2015
Zhongshan Hospital, Fudan University
Residency
Jun 2013
Zhongshan Hospital, Fudan University
Medical Internship

Publications

3Publications

31Reads

35Profile Views

76PubMed Central Citations

Clinical feasibility assessment of T3 sub-stage in rectal cancer using MRI

Iran J Radiol. 2018 Mar 10;15(2)

Iranian Journal of Radiology

Abstract

Background: MRI predicted distance of mesorectal extension (mrDME) in rectal cancer is one of the independent risk factors forrecurrence and poor overall survival. In T3 rectal cancer, if no lymph node or distant metastasis is seen, the selection of optimumtreatment is based on the distance of mesorectal extension. Therefore, it is very crucial to investigate the reproducibility of DME inT3 rectal cancer.

Objectives: To investigate the reproducibility of the distance of mesorectal extension by tumor invasion in T3 stage rectal cancerby evaluating sub-stages T3a, T3b T3c and T3d individually versus T3a, T3b (T3ab) and T3c, T3d (T3cd) combined together using MRI.

Patients and Methods: From July 2014 to December 2015, 188 patients with surgically and histologically confirmed T3 rectal cancerwho underwent preoperative MRI were enrolled into this study. Two blinded radiologists evaluated the maximum distance ofmesorectal extension (mrDME) in T2 weighted image in MRI. The study population was sub classified into T3a (< 1 mm), T3b (1 - 5mm), T3c (5 - 15 mm) and T3d (> 15 mm) according to the distance of mesorectal extension by tumor invasion. The inter-observerand intra-observer agreements were then assessed using kappa (k) coefficient of agreement and intraclass correlation coefficient(ICC).

Results: Difference in the value of inter-/intra-observer kappa, and inter-/intra-observer ICC between the two groups was very distinct.In the individual group (T3a, T3b, T3c and T3d), the inter-observer and intra-observer (k) for the mrDME was 0.700 and 0.718respectively; the inter-observer and intra-observer ICC was 0.772 and 0.786 respectively. In the combined group (T3ab and T3cd), theinter-observer and intra-observer kappa (k) for the mrDME was 0.819 and 0.883 respectively; the inter-observer and intra-observerICC was 0.829 and 0.796 respectively.

Conclusion: There was a distinct increase in the kappa and ICC value in the combined group compared with the individual group.This high reproducibility result suggested that it is more reliable to measure T3ab and T3cd combined together than individually.This finding can play a crucial role in the management of rectal cancer and clinical decision making for non-expert radiologists innon-academic setting.

Keywords: Rectal Cancer, T3 Sub-Staging, Reproducibility Test, MRI, Distance of Mesorectal Extension, mrDME

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March 2018

Impact Factor 0.500

92 Reads

Clinical value of MRI-detected extramural venous invasion in rectal cancer.

J Dig Dis 2017 Jan;18(1):2-12

Department of Radiology, Zhongshan Hospital and Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai Institute of Medical Imaging, Shanghai, China.

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Source
http://doi.wiley.com/10.1111/1751-2980.12439
Publisher Site
http://dx.doi.org/10.1111/1751-2980.12439DOI Listing
January 2017
16 Reads
3 Citations
1.924 Impact Factor

High expression of lncRNA MALAT1 suggests a biomarker of poor prognosis in colorectal cancer.

Int J Clin Exp Pathol 2014 15;7(6):3174-81. Epub 2014 May 15.

Department of Colorectal Surgery, Fudan University Shanghai Cancer Center Shanghai 200032, China ; Department of Oncology, Shanghai Medical College, Fudan University Shanghai 200032, China.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097248PMC
May 2015
15 Reads
73 Citations
1.783 Impact Factor

Top co-authors

Ye Xu
Ye Xu

Fudan University Shanghai Cancer Center

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Wei-Lie Gu
Wei-Lie Gu

Fudan University

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Guo-Xiang Cai
Guo-Xiang Cai

Fudan University

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San-jun Cai
San-jun Cai

Fudan University

1
Xin-xiang Li
Xin-xiang Li

The Second Military Medical University

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Yu-wei Wang
Yu-wei Wang

Peking University School of Stomatology

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Meng Su Zeng
Meng Su Zeng

Zhongshan Hospital

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Hong-Tu Zheng
Hong-Tu Zheng

Fudan University

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De-Bing Shi
De-Bing Shi

Fudan University

1