Pratik Pandharipande

Pratik Pandharipande

UNVERIFIED PROFILE

Are you Pratik Pandharipande?   Register this Author

Register author
Pratik Pandharipande

Pratik Pandharipande

Publications by authors named "Pratik Pandharipande"

Are you Pratik Pandharipande?   Register this Author

100Publications

2873Reads

36Profile Views

Association of Hypoactive and Hyperactive Delirium With Cognitive Function After Critical Illness.

Crit Care Med 2020 Jun;48(6):e480-e488

Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center and the Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000004313DOI Listing
June 2020

Association of neuronal repair biomarkers with delirium among survivors of critical illness.

J Crit Care 2020 Apr 16;56:94-99. Epub 2019 Dec 16.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcrc.2019.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080575PMC
April 2020

A Brief Informant Screening Instrument for Dementia in the ICU: The Diagnostic Accuracy of the AD8 in Critically Ill Adults Suspected of Having Pre-Existing Dementia.

Dement Geriatr Cogn Disord 2019 7;48(5-6):241-249. Epub 2020 Apr 7.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000490379DOI Listing
April 2020

Statistical analysis plan for the Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients with Acute Respiratory Failure trial.

Crit Care Resusc 2020 Mar;22(1):63-71

Critical Illness, Brain Dysfunction, and Survivorship Center, Vanderbilt University Medical Center, Nashville, TN, USA.

View Article

Download full-text PDF

Source
March 2020

Worse Than Death: Survey of Public Perceptions of Disability Outcomes After Hypothetical Traumatic Brain Injury.

Ann Surg 2020 Jan 14. Epub 2020 Jan 14.

Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SLA.0000000000003389DOI Listing
January 2020

Special Considerations for the Aging Brain and Perioperative Neurocognitive Dysfunction.

Anesthesiol Clin 2019 Sep 17;37(3):521-536. Epub 2019 Jun 17.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University School of Medicine, 1211 21st Avenue South, 422 MAB, Nashville, TN 37212, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anclin.2019.04.010DOI Listing
September 2019

In Response.

Anesth Analg 2019 08;129(2):e60

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0000000000003855DOI Listing
August 2019

In the ICU - delirium post cardiac arrest.

Curr Opin Crit Care 2019 06;25(3):218-225

Division of Critical Care Medicine, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MCC.0000000000000615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902119PMC
June 2019

Melatonin in Critical Care.

Crit Care Clin 2019 Apr 30;35(2):329-340. Epub 2019 Jan 30.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University Medical Center, 1211 21st Avenue South, Medical Arts Building, Suite 422, Nashville, TN 37212, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07490704183077
Publisher Site
http://dx.doi.org/10.1016/j.ccc.2018.11.008DOI Listing
April 2019

Long-term Cognitive and Functional Impairments After Critical Illness.

Anesth Analg 2019 04;128(4):772-780

From the Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0000000000004066DOI Listing
April 2019

Delirium Monitoring: Yes or No? That Is The Question.

Am J Crit Care 2019 03;28(2):127-135

Annachiara Marra is an anesthesiologist, Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, and Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy. Katarzyna Kotfis is an assistant professor, Department of Anesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University, Szczecin, Poland. Annmarie Hosie is a postdoctoral research fellow, IMPACCT-Improving Palliative, Aged and Chronic Care through Clinical Research and Translation, Faculty of Health, University of Technology Sydney, Ultimo, Australia. Alasdair M. J. MacLullich is a professor, Edinburgh Delirium Research Group, Geriatric Medicine Unit, University of Edinburgh, Edinburgh, Scotland. Pratik P. Pandharipande is a professor, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and Critical Illness, Brain Dysfunction and Survivorship (CIBS) Center, Vanderbilt University Medical Center. E. Wesley Ely is a professor, Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Center for Health Services Research, Department of Medicine, and Center for Quality Aging, Vanderbilt University Medical Center, and associate director for research, Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, and CIBS Center, Vanderbilt University Medical Center. Brenda T. Pun is an advanced practice nurse, CIBS Center, Vanderbilt University Medical Center.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4037/ajcc2019874DOI Listing
March 2019

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness.

N Engl J Med 2018 12 22;379(26):2506-2516. Epub 2018 Oct 22.

From the Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh (T.D.G.); the Pulmonary, Critical Care, and Sleep Medicine Division, Department of Medicine, Ohio State University Wexner Medical Center, Columbus (M.C.E.), and the Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic Foundation, Cleveland (R.D.H.) - both in Ohio; the Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill (S.S.C.), the Section on Critical Care, Department of Anesthesiology, Wake Forest Baptist Health, Winston-Salem (D.L.B.), and Cone Health System, Greensboro (D.J.F.) - all in North Carolina; the Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington School of Medicine, Seattle (C.L.H.); the Department of Anesthesiology, University of Maryland School of Medicine, Baltimore (P.R.); the Division of Critical Care Medicine, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, New York (M.N.G.); the Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, Denver Health Medical Center, Denver (I.S.D.); the Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California at San Diego, San Diego (A.M., R.L.O.); the Division of Pulmonary, Critical Care, Sleep, and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis (B.K.); the Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT (M.A.P.); the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor (R.C.H.); the Division of Pulmonary, Critical Care, and Occupational Medicine, Department of Medicine, University of Iowa Hospitals and Clinics, Iowa City (G.A.S.); , and the Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia (W.D.S.); the Center for Clinical Effectiveness, Baylor Scott and White Health, Dallas (A.L.M.); and the Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center (J.L.T., R.C., B.T.P., C.S., L.M.B., J.C.J., P.P.P., N.E.B., C.G.H., M.B.P., J.L.S., G.R.B., R.S.D., E.W.E.), the Center for Health Services Research (R.C., J.C.J., C.S., N.E.B., R.S.D., E.W.E.), the Center for Quality Aging (N.E.B., E.W.E.), the Division of Allergy, Pulmonary, and Critical Care Medicine (J.C.J., C.S., N.E.B., G.R.B., E.W.E.), the Division of General Internal Medicine and Public Health (R.S.D.), Department of Medicine, the Department of Biostatistics (J.L.T., R.C.), the Department of Psychiatry (J.C.J.), the Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology (P.P.P., C.G.H.), the Division of Trauma and Surgical Critical Care, Department of Surgery (M.B.P.), and the Department of Pharmaceutical Services (J.L.S.), Vanderbilt University School of Medicine, Vanderbilt University School of Nursing (L.M.B.), and the Anesthesia Service (P.P.P., C.G.H.), Research Service (J.C.J.), Surgical Service (M.B.P.), and Geriatric Research, Education, and Clinical Center Service (R.S.D., E.W.E.), Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System - all in Nashville.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1808217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364999PMC
December 2018

Antimicrobial exposure and the risk of delirium in critically ill patients.

Crit Care 2018 12 12;22(1):337. Epub 2018 Dec 12.

Critical Illness, Brain dysfunction, Survivorship (CIBS) Center, 2525 West End Avenue, Nashville, TN, 37232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13054-018-2262-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291937PMC
December 2018

Delirium Monitoring in Neurocritically Ill Patients: A Systematic Review.

Crit Care Med 2018 11;46(11):1832-1841

Critical Illness, Brain dysfunction, and ICU Survivorship (CIBS) Center, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000003349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185789PMC
November 2018

Co-Occurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness.

Crit Care Med 2018 09;46(9):1393-1401

Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000003218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095801PMC
September 2018

Acute Brain Dysfunction: Development and Validation of a Daily Prediction Model.

Chest 2018 08 24;154(2):293-301. Epub 2018 Mar 24.

Department of Medicine, Division of General Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, TN; Geriatric Research, Education and Clinical Center (GRECC) of the VA Tennessee Valley Healthcare System, Nashville, TN; Center for Health Services Research, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN; Center for Quality Aging, Vanderbilt University Medical Center, Nashville, TN. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chest.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113630PMC
August 2018

Light Sedation Is the Goal: Making the Evidence Heavier.

Crit Care Med 2018 06;46(6):1003-1004

School of Pharmacy, Northeastern University; and Division of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, MA Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000003142DOI Listing
June 2018

A Call for Electronic Health Record-based Data Sharing for Clinical Trials in Critical Care.

J Med Syst 2018 May 25;42(7):115. Epub 2018 May 25.

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10916-018-0984-8
Publisher Site
http://dx.doi.org/10.1007/s10916-018-0984-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138868PMC
May 2018

Postoperative delirium.

Presse Med 2018 Apr 19;47(4 Pt 2):e53-e64. Epub 2018 Apr 19.

Vanderbilt University Medical Center, department of anesthesiology, Nashville, TN, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lpm.2018.03.012DOI Listing
April 2018

Systematic review of prediction models for delirium in the older adult inpatient.

BMJ Open 2018 04 28;8(4):e019223. Epub 2018 Apr 28.

Department of Anesthesiology, University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2017-019223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931306PMC
April 2018

Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study.

Lancet Respir Med 2018 03;6(3):213-222

ICU Delirium and Cognitive Impairment Study Group at the Vanderbilt University School of Medicine, Nashville, Tennessee, USA; Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Center for Quality Aging, Vanderbilt University School of Medicine, Nashville, TN, USA; Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(18)30062-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709878PMC
March 2018

Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability.

Intensive Care Med 2018 03 9;44(3):345-355. Epub 2018 Mar 9.

Department of Critical Care Medicine and Clinical Research, Investigation and Systems Modeling of Acute Illnesses Center, University of Pittsburgh, Pittsburgh, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00134-018-5120-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870884PMC
March 2018

Tracheostomy risk factors and outcomes after severe traumatic brain injury.

Brain Inj 2016 14;30(13-14):1642-1647. Epub 2016 Oct 14.

a Departments of Surgery and Neurosurgery, Division of Trauma & Surgical Critical Care , Vanderbilt University Medical Center , Nashville , TN , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02699052.2016.1199915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358996PMC
January 2018

ICU sedation with dexmedetomidine after severe traumatic brain injury.

Brain Inj 2016 26;30(10):1266-70. Epub 2016 Jul 26.

a Departments of Surgery and Neurosurgery , Division of Trauma & Surgical Critical Care.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02699052.2016.1187289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5160042PMC
December 2017

Intensive Care Unit Delirium and Intensive Care Unit-Related Posttraumatic Stress Disorder.

Surg Clin North Am 2017 Dec 5;97(6):1215-1235. Epub 2017 Oct 5.

Division of Trauma, Surgical Critical Care, and Emergency General Surgery, Department of Surgery, Section of Surgical Sciences, Center for Health Services Research, Vanderbilt Brain Institute, Vanderbilt University Medical Center, 1211 21st Avenue South, Medical Arts Building, Suite 404, Nashville, TN 37212, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.suc.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747308PMC
December 2017

Creation and Execution of a Novel Anesthesia Perioperative Care Service at a Veterans Affairs Hospital.

Anesth Analg 2017 11;125(5):1526-1531

From the *Department of Anesthesiology, Pain Management & Perioperative Medicine, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee; †Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee; ‡Department of Anesthesiology, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee; §Department of Orthopaedic Surgery, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee; ‖Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee; ¶Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee; #Department of Urology, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee; and **Department of Surgery, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0000000000001930DOI Listing
November 2017

Worldwide Survey of the "Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment" (ABCDEF) Bundle.

Crit Care Med 2017 Nov;45(11):e1111-e1122

1Department of Rehabilitation, Ancelle Hospital, Cremona, Italy. 2Geriatric Research Group, Brescia, Italy. 3Department of Anesthesia, Critical Care and Emergency, SpedaliCivili University Hospital, Brescia, Italy. 4Division of Pulmonary and Critical Care and Health Services Research, Vanderbilt University and VA Geriatric Research Education Clinical Center (GRECC), Nashville, TN. 5Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Mumbai, India. 6Department of Critical Care, D'or Institute for Research and Education and Post-Graduate Program Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. 7Addis Hiwot General Hospital, Addis Ababa, Ethiopia. 8Medical Intensive Care Unit, Hôpital Saint-Louis, ECSTRA team, Biostatistics and clinical epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cité, CRESS), INSERM, Paris Diderot Sorbonne University, Paris, France. 9School of Medicine and Surgery, University of Milano-Bicocca, Milano Geriatric Clinic, San Gerardo University Hospital, Monza, Italy. 10Department of Anaesthesia and Intensive Care, Medical Centre, Hungarian Defence Force, Budapest, Hungary. 11Interdepartmental Division of Critical Care Medicine and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada. 12University Health Network, Toronto, ON, Canada. 13CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh and UPMC Health System, Pittsburgh, PA. 14International Research Project Humanizing Intensive Care (Proyecto HU-CI), Intensive Care Unit, Hospital Universitario de Torrejón, Madrid. Spain. 15Department of Emergency and Critical Care Medicine, Tokai University, School of Medicine, Kanagawa, Japan. 16Department of Pulmonary and Critical Care Medicine Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. 17General Hospital Novo mesto, Novo mesto, Slovenia. 18Department of Anaesthesia, Intensive Care and Acute Poisioning, Pomeranian Medical University, Szczecin, Poland. 19Aga Khan University Hospital, Nairobi, Kenya. 20Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine Vanderbilt University Medical Center, Nashville, TN. 21Siriraj Hospital, Bangkok, Thailand. 22Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing, China. 23Department of Intensive Care Medicine Raymond Poincaré Hospital, Paris, France. 24School of Clinical Sciences, Faculty of Medicine, Monash University & Medical Center, Melbourne, VIC, Australia. 25University New South Wales, Clinical School of Medicine, NSW, Australia. 26Department of Medicine, McGill University, Montreal, QC, Canada. 27Regroupement de Soins Critiques Respiratoires, Réseau de Santé Respiratoire FRQS, Montreal, QC, Canada. 28Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. 29Krembil Neuroscience Centre, University Health Network, Toronto, ON, Canada. 30Department of Intensive Care Medicine, Brain Center Rudolf Magnus, Utrecht University, University Medical Center Utrecht, The Netherlands. 31Department of Neurocritical Care, University College London Hospitals, UCLH/UCL National Institute for Health Research Biomedical Research Centre, London, United Kingdom. 32Acute & General Medicine, Yamaguchi Graduate School of Medicine, Yamaguchi, Japan. 33Department of Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy. 34Department of Anesthesia, Critical Care and Emergency, Spedali Civili University Hospital, Brescia, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000002640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640479PMC
November 2017

Delirium and Catatonia in Critically Ill Patients: The Delirium and Catatonia Prospective Cohort Investigation.

Crit Care Med 2017 Nov;45(11):1837-1844

1Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN. 2Veteran's Affairs Tennessee Valley Healthcare System, Geriatrics, Research, Education and Clinical Center (GRECC), Nashville, TN. 3Division of General Internal Medicine and Public Health, Department of Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN. 4Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN. 5Department of Critical Care Medicine, Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, University of Pittsburgh School of Medicine, Pittsburgh, PA. 6Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN. 7Department of Psychiatry, Penn State Medical School, Hershey Medical Center, Hershey, PA. 8Department of Psychiatry, Beth Israel Deaconess Hospital-Plymouth, Plymouth, MA. 9Division of Pulmonary and Critical Care, Department of Medicine, and the Institute for Medicine and Public Health, the Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000002642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678952PMC
November 2017

Persistence of Delirium after Cessation of Sedatives and Analgesics and Impact on Clinical Outcomes in Critically Ill Patients.

Pharmacotherapy 2017 Nov 17;37(11):1357-1365. Epub 2017 Oct 17.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/phar.2021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681431PMC
November 2017

Subsyndromal Delirium and Institutionalization Among Patients With Critical Illness.

Am J Crit Care 2017 Nov;26(6):447-455

Nathan E. Brummel is an assistant professor and E. Wesley Ely is a professor, Department of Medicine, Center for Quality Aging and the Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee. Dr Ely is also the associate director for research for the Geriatric Research, Education, and Clinical Center Service (GRECC), Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee. Leanne M. Boehm is a postdoctoral fellow, Vanderbilt University School of Nursing, a quality scholar, GRECC, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, and a research nurse, Department of Medicine, Center for Health Services Research, Vanderbilt University Medical Center. Timothy D. Girard is an associate professor, Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Pratik P. Pandharipande is a professor and Christopher G. Hughes is an associate professor, Department of Anesthesiology, Vanderbilt University Medical Center. James C. Jackson is a research associate professor, Department of Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, and Mayur B. Patel is an assistant professor, Department of Surgery, Vanderbilt University Medical Center. Jin H. Han is an associate professor, Department of Emergency Medicine and Center for Quality Aging, Vanderbilt University Medical Center. Eduard E. Vasilevskis is a staff physician, GRECC, Department of Veterans Affairs Medical Center, VA Tennessee Valley Healthcare System, and an assistant professor, Department of Medicine and Center for Health Services Research, Vanderbilt University Medical Center. Jennifer L. Thompson is a biostatistician and Rameela Chandrasekhar is an assistant professor, Department of Biostatistics, Vanderbilt University School of Medicine. Gordon R. Bernard is associate vice-chancellor for research and a professor, Department of Medicine, Vanderbilt University Medical Center. Robert S. Dittus is director, GRECC, Department of Veterans Affairs Medical Center, VA Tennessee Valley Healthcare System, and a professor, Department of Medicine, Vanderbilt University Medical Center.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4037/ajcc2017263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831547PMC
November 2017

Delirium and Benzodiazepines Associated With Prolonged ICU Stay in Critically Ill Infants and Young Children.

Crit Care Med 2017 Sep;45(9):1427-1435

1Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN. 2Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN. 3Department of Psychiatry, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY. 4Department of Pediatrics, University of South Carolina School of Medicine Greenville, Greenville, SC. 5Department of Psychiatry, Children's Hospital of Philadelphia, Philadelphia, PA. 6Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN. 7Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN. 8Department of Internal Medicine, Center for Health Services Research, Vanderbilt University Medical Center, Nashville, TN. 9Tennessee Valley Veterans Administration (VA) Geriatric Research Education Clinical Center (GRECC), Nashville, TN. 10Department of Psychiatry, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000002515DOI Listing
September 2017

Humanizing the Treatment of Hyperactive Delirium in the Last Days of Life.

JAMA 2017 09;318(11):1014-1015

Division of Allergy and Pulmonary Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2017.11466DOI Listing
September 2017

Perceptions of Workload Burden and Adherence to ABCDE Bundle Among Intensive Care Providers.

Am J Crit Care 2017 Jul;26(4):e38-e47

Leanne M. Boehm is a postdoctoral fellow, Vanderbilt University School of Nursing, a quality scholar, VA Tennessee Valley Healthcare System, Geriatric Research, Education and Clinical Center (GRECC), and a research nurse, Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of biostatistics, School of Nursing and School of Medicine, Vanderbilt University. Eduard E. Vasilevskis is a staff physician, VA Tennessee Valley Healthcare System, GRECC and an assistant professor of medicine, Center for Health Services Research, Vanderbilt University. Nancy Wells is a research professor, Vanderbilt University School of Nursing and Vanderbilt University Medical Center, Nashville, Tennessee. Pratik Pandharipande is a professor of anesthesiology and surgery, Vanderbilt University School of Medicine and a staff physician, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System. E. Wesley Ely is associate director, VA Tennessee Valley Healthcare System, GRECC, and a professor, Department of Medicine and Center for Health Services Research, Vanderbilt University. Lorraine C. Mion is a research professor and interim director of the Center of Excellence in Critical and Complex Care, The Ohio State University School of Nursing, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4037/ajcc2017544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714508PMC
July 2017

Delirium After Transcatheter Aortic Valve Replacement.

Am J Crit Care 2017 Jul;26(4):e58-e64

Jennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4037/ajcc2017474DOI Listing
July 2017

Surgery and Anesthesia Exposure Is Not a Risk Factor for Cognitive Impairment After Major Noncardiac Surgery and Critical Illness.

Ann Surg 2017 06;265(6):1126-1133

*Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine and Center for Health Services Research, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee †Section of Surgical Sciences, Departments of Surgery, Neurosurgery and Hearing and Speech Sciences, Division of Trauma and, Surgical Critical Care, and Emergency General Surgery, Vanderbilt Brain Institute, Center for Health Services Research, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee ‡Department of Medicine, Division of Pulmonary and Critical Care Medicine and Center for Health Services Research, Vanderbilt University Medical Center, Research Service, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee §Department of Medicine, Division of Pulmonary and Critical Care Medicine and Center for Health Services Research, Vanderbilt University Medical Center, Geriatric Research, Education and Clinical Center Service, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee ¶Department of Surgery, Radiology, and Radiological Sciences, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee ||Department of Medicine, Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee **Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee ††Department of Medicine, Division of Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee ‡‡Section of Surgical Sciences, Department of Surgery, Division of Trauma and Surgical Critical Care, and Emergency General Surgery, Vanderbilt University Medical Center, Nashville, Tennessee §§Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Utah School of Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah ¶¶George E. Wahlen Department of Veterans Affairs Medical Center, Veterans Administration Salt Lake City Health Care System, Salt Lake City, Utah ||||Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Seattle Division, Veterans Affairs Puget Sound Health Care System, Seattle, Washington ***Clinical Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, the Netherlands †††Departments of Anesthesiology and Surgery, Division of Anesthesiology Critical Care Medicine, Vanderbilt University Medical Center, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SLA.0000000000001885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856253PMC
June 2017

Acute Kidney Injury as a Risk Factor for Delirium and Coma during Critical Illness.

Am J Respir Crit Care Med 2017 06;195(12):1597-1607

12 Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201603-0476OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476907PMC
June 2017

Daily Lowest Hemoglobin and Risk of Organ Dysfunctions in Critically Ill Patients.

Crit Care Med 2017 May;45(5):e479-e484

1Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN. 2Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000002288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398896PMC
May 2017

Organizational Domains and Variation in Attitudes of Intensive Care Providers Toward the ABCDE Bundle.

Am J Crit Care 2017 May;26(3):e18-e28

Leanne M. Boehm is a postdoctoral fellow, Vanderbilt University School of Nursing, a quality scholar, VA Tennessee Valley Healthcare System, Geriatric Research, Education and Clinical Center (GRECC), and a research nurse, Department of Medicine, Center for Health Services Research, Vanderbilt University, Nashville, Tennessee. Eduard E. Vasilevskis is a staff physician, VA Tennessee Valley Healthcare System, GRECC and an assistant professor of medicine, Center for Health Services Research, Vanderbilt University. Mary S. Dietrich is a professor of biostatistics, School of Nursing and School of Medicine, Vanderbilt University. Nancy Wells is a research professor, Vanderbilt University School of Nursing and Vanderbilt University Medical Center, Nashville, Tennessee. E. Wesley Ely is associate director, VA Tennessee Valley Healthcare System, GRECC, and a professor, Department of Medicine and Center for Health Services Research, Vanderbilt University. Pratik Pandharipande is a professor of anesthesiology and surgery, Vanderbilt University School of Medicine and a staff physician, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System. Lorraine C. Mion is a research professor and interim director of the Center of Excellence in Critical and Complex Care, The Ohio State University School of Nursing, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4037/ajcc2017297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693381PMC
May 2017

The ABCDEF Bundle in Critical Care.

Crit Care Clin 2017 Apr;33(2):225-243

Division of Trauma, Surgical Critical Care, and Emergency General Surgery, Section of Surgical Sciences, Department of Surgery, Center for Health Services Research, Vanderbilt University Medical Center, 1211 21st Avenue South, Medical Arts Building, Suite 404, Nashville, TN 37212, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccc.2016.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351776PMC
April 2017

Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 1 Efficacy: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations.

Anesth Analg 2017 03;124(3):821-830

From the *Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York; †Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York; ‡Department of Anesthesiology, Tufts School of Medicine, Boston, Massachusetts; §Department of Pediatrics, Southern Illinois University School of Medicine, Springfield, Illinois; ‖Department of Pediatrics, St John's Children's Hospital, Springfield, Illinois; ¶Department of Anesthesia, Harvard Medical School, Boston, Massachusetts; #Department of Anesthesiology, Boston Children's Hospital, Boston, Massachusetts; **Department of Anesthesia, University of Iowa, Iowa City; ††Pediatric Gastroenterology, University of Massachusetts Medical Center, University of Massachusetts Medical School, Worcester, Massachusetts; ‡‡Department of Anesthesiology, Harvard Medical School, Boston Children's Hospital, Boston, Massachusetts; §§Department of Emergency Medicine, University of Minnesota Medical School, Minneapolis, Minnesota; ‖‖Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, Minnesota; ¶¶Department of Gastroenterology and Hepatology, Cleveland Clinic Lerner College of Medicine of Case Western University, Cleveland, Ohio; ##Pediatric Critical Care, Kosair Children's Hospital, University of Louisville School of Medicine, Louisville, Kentucky; ***Section for Professional Standards, American Society of Anesthesiologists Children's Hospital Colorado, University of Colorado School of Medicine, Denver, Colorado; †††Department of Anesthesiology, Hôpital Armand Trousseau, Paris, France; ‡‡‡Department of Pharmacology and Foundational Sciences, East Carolina University, Greenville, North Carolina; §§§Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York; ‖‖‖Division of Anesthesiology and CCM, Hadassah University Hospital, The Hebrew University of Jerusalem School of Medicine, Jerusalem, Israel; ¶¶¶Annovation BioPharma, Cambridge, Massachusetts; ###Department of Anesthesiology, University of Hong Kong, Hong Kong, China; ****Department of Anesthesiology, Women and Children's Hospital of Buffalo, SUNY at Buffalo, Buffalo, New York; ††††Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, Virginia; ‡‡‡‡Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee; §§§§Analgesic Concepts LLC, Arlington, Virginia; ‖‖‖‖Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts; ¶¶¶¶Department of Critical Care Medicine and Neuroscience Institute, Maine Medical Center, Portland, Maine; ####Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, North Carolina; *****Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington; †††††Department of Anesthesiology & Critical Care Medicine, Josie Robertson Surgery Center, Memorial Sloan Kettering Cancer Center, New York, New York; and ‡‡‡‡‡Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1213/ANE.0000000000001566DOI Listing
March 2017

Are you Ernest Shackleton the polar explorer? Refining the criteria for delirium and brain dysfunction in sepsis.

J Intensive Care 2017 7;5:23. Epub 2017 Mar 7.

Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.

View Article

Download full-text PDF

Source
http://jintensivecare.biomedcentral.com/articles/10.1186/s40
Publisher Site
http://dx.doi.org/10.1186/s40560-017-0218-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341444PMC
March 2017

Intraoperative cerebral oxygenation, oxidative injury, and delirium following cardiac surgery.

Free Radic Biol Med 2017 02 27;103:192-198. Epub 2016 Dec 27.

Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA; Division of Cardiothoracic Anesthesiology, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2016.12.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258679PMC
February 2017

Intensive Care Unit Delirium: A Review of Diagnosis, Prevention, and Treatment.

Anesthesiology 2016 12;125(6):1229-1241

From the Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ALN.0000000000001378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119532PMC
December 2016

The evolving approach to sedation in ventilated patients: a real world perspective.

Ann Transl Med 2016 Dec;4(24):494

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/atm.2016.12.56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233542PMC
December 2016

Employment Outcomes After Critical Illness: An Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychological Dysfunction in ICU Survivors Cohort.

Crit Care Med 2016 Nov;44(11):2003-2009

1Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 2Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 3Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 4Department of Psychiatry, Vanderbilt Medical Center, Nashville, TN. 5Department of Health Policy, Vanderbilt University School of Medicine, Nashville, TN. 6Center for Quality of Aging, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 7Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 8Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN. 9Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069078PMC
http://dx.doi.org/10.1097/CCM.0000000000001849DOI Listing
November 2016

Antipsychotic prescribing patterns during and after critical illness: a prospective cohort study.

Crit Care 2016 11 24;20(1):378. Epub 2016 Nov 24.

Clinical Research, Investigation, and Systems Modeling of Acute illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA, 15261, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13054-016-1557-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122157PMC
November 2016

Endothelial Activation and Blood-Brain Barrier Injury as Risk Factors for Delirium in Critically Ill Patients.

Crit Care Med 2016 09;44(9):e809-17

1Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN.2Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.3Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Health Care System, Nashville, TN.4Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.5Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.6Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN.7Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Health Care System, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000001739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987204PMC
September 2016

The impact of lymphopenia on delirium in ICU patients.

PLoS One 2015 20;10(5):e0126216. Epub 2015 May 20.

Division of Allergy/Pulmonary/Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America; Veterans Affairs Tennessee Valley Geriatric Research, Education and Clinical Center (GRECC), Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126216PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439144PMC
April 2016

The Evolving Approach to Brain Dysfunction in Critically Ill Patients.

JAMA 2016 Apr;315(14):1455-6

Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2016.2708DOI Listing
April 2016

The Preschool Confusion Assessment Method for the ICU: Valid and Reliable Delirium Monitoring for Critically Ill Infants and Children.

Crit Care Med 2016 Mar;44(3):592-600

1Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN.2Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN.3Department of Psychiatry, New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.4Department of Psychiatry, Massachusetts General Hospital, Boston, MA.5Department of Psychiatry, Georgia Regents University, Augusta, GA.6Department of Psychiatry, Kalispell Regional Healthcare, Kalispell, MT.7Department of Psychiatry, Vanderbilt University Medical Center, Nashville, TN.8Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.9Department of Developmental Medicine, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN.10Department of Internal Medicine, Center for Health Services Research and Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, and the Tennessee Valley VA GRECC, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000001428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764386PMC
March 2016

Validity of a Modified Sequential Organ Failure Assessment Score Using the Richmond Agitation-Sedation Scale.

Crit Care Med 2016 Jan;44(1):138-46

1Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN.2Section of Hospital Medicine, Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.3Geriatric Research, Education, and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.4Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN.5Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.6Department of Urology, Vanderbilt University School of Medicine, Nashville, TN.7Department of Clinical Epidemiology and Biostatistics, Graduate School of Medicine, Osaka University, Osaka, Japan.8Advanced Medical Emergency and Critical Care Center, Yamaguchi University Hospital, Yamaguchi, Japan.9Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000001375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748963PMC
January 2016

Population Pharmacokinetics of Fentanyl in the Critically Ill.

Crit Care Med 2016 Jan;44(1):64-72

1Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.2Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.3Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.4Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN.5Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.6Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN.7Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN.8Aegis Sciences Corporation, Nashville, TN.9Center for Quality Aging, Vanderbilt University School of Medicine, Nashville, TN.10Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.11Division of Rheumatology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000001347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755937PMC
January 2016

Cognitive Dysfunction, Delirium, and Stroke in Cardiac Surgery Patients.

Semin Cardiothorac Vasc Anesth 2015 Dec;19(4):309-17

Vanderbilt University, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/1089253215570062
Publisher Site
http://dx.doi.org/10.1177/1089253215570062DOI Listing
December 2015

Intraoperative protective ventilation: too early to redefine management parameters?

BMJ 2015 Sep 30;351:h5126. Epub 2015 Sep 30.

Vanderbilt University Medical Center, Nashville, TN 37212, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmj.h5126DOI Listing
September 2015

What's new in post-ICU cognitive impairment?

Intensive Care Med 2015 Apr 27;41(4):708-11. Epub 2015 Jan 27.

Nashville VA Medical Center, Veterans Affairs (VA) Tennessee Valley Healthcare System, Nashville, TN, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00134-014-3632-xDOI Listing
April 2015

Risk factors for postoperative delirium.

Lancet Psychiatry 2014 Nov 5;1(6):404-6. Epub 2014 Nov 5.

Department of Anesthesiology, Division of Anesthesiology Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2215-0366(14)00012-1DOI Listing
November 2014

Burst suppression on processed electroencephalography as a predictor of postcoma delirium in mechanically ventilated ICU patients.

Crit Care Med 2014 Oct;42(10):2244-51

1Department of Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA. 2Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN. 3Center for Health Services Research, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN. 4Geriatric Research, Education, and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 5Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 6Division of Critical Care, Department of Anesthesia, Vanderbilt University Medical Center, Nashville, TN. 7Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000000522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493889PMC
October 2014

Statins and delirium during critical illness: a multicenter, prospective cohort study.

Crit Care Med 2014 Aug;42(8):1899-909

1Rehabilitation and Aged Care Unit, Hospital Ancelle, Cremona, Italy. 2Geriatric Research Group, Brescia, Italy. 3Center for Quality Aging, Vanderbilt University School of Medicine, Nashville, TN. 4Division of Critical Care, Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN. 5Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 6Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN. 7Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN. 8Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 9Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 10Department of Emergency Medicine, Vanderbilt University School of Medicine, Nashville, TN. 11Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 12Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN. 13Research Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 14Division of Neurology, Department of Medicine, Department of Anesthesiology, and Department of Neurobiology, Duke University Medical Center, Durham, NC.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000000398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103957PMC
August 2014

Only a small subset of sedation-related delirium is innocuous: we cannot let our guard down.

Am J Respir Crit Care Med 2014 Jun;189(11):1443-4

1 Vanderbilt University School of Medicine Nashville, Tennessee and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201403-0506LEDOI Listing
June 2014

Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study.

Lancet Respir Med 2014 May 7;2(5):369-79. Epub 2014 Apr 7.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, TN, USA; Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(14)70051-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107313PMC
May 2014

An international career development survey of critical care practitioners*.

Crit Care Med 2014 Apr;42(4):e300-3

1Veterans Affairs (VA) Tennessee Valley Healthcare System, Nashville VA Medical Center, Nashville, TN. 2Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN. 3Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA. 4Division of Critical Care, Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000000137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959251PMC
April 2014

Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation.

Crit Care Med 2014 Feb;42(2):369-77

1Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 2Center for Health Services Research, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 3Center for Quality of Aging, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 4Geriatric Research, Education and Clinical Center Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 5Department of Psychiatry, Vanderbilt Medical Center, Nashville, TN. 6Clinical Research Center of Excellence, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 7Division of Critical Care, Department of Anesthesiology, Vanderbilt School of Medicine, Nashville, TN. 8Anesthesia Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN. 9Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN. 10Institute for Medicine and Public Heath, Vanderbilt University School of Medicine, Nashville, TN. 11Department of Internal Medicine, Yale School of Medicine, New Haven, CT.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0b013e3182a645bdDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947028PMC
February 2014

Are we offtrack using propofol for sedation after traumatic brain injury?

Crit Care Med 2014 Jan;42(1):211-2

Department of Anesthesiology, University Hospital RWTH Aachen, Aachen, Germany Department of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, TN Department of Anaesthesia and Surgical Outcomes Research Centre, University College London Hospital; and Wellcome Department of Imaging Neuroscience, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://pdfs.journals.lww.com/ccmjournal/2014/01000/Are_We_Of
Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/CCM.0000000000000009DOI Listing
January 2014

Long-term cognitive impairment after critical illness.

N Engl J Med 2014 01;370(2):185-6

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1313886DOI Listing
January 2014

Neural and immune consequences of traumatic brain injury: does propofol reduce the impact?

Anesthesiology 2013 Dec;119(6):1241-3

*Department of Anaesthesia and Surgical Outcomes Research Centre, University College London Hospital and Wellcome Department of Imaging Neuroscience, University College London, London, United Kingdom. † Department of Anesthesiology, University Hospital RWTH Aachen, Aachen, Germany. ‡ Department of Anesthesiology, Division of Critical Care, Vanderbilt University Medical Center, Nashville, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ALN.0000000000000019DOI Listing
December 2013

Anesthesia for liver transplantation in United States academic centers: intraoperative practice.

J Clin Anesth 2013 Nov 30;25(7):542-50. Epub 2013 Aug 30.

Department of Anesthesiology, Tufts Medical Center and Tufts University School of Medicine, Boston, MA 02111, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinane.2013.04.017DOI Listing
November 2013

Daily sedation interruption versus targeted light sedation strategies in ICU patients.

Crit Care Med 2013 Sep;41(9 Suppl 1):S39-45

Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0b013e3182a168c5DOI Listing
September 2013

The pain, agitation, and delirium care bundle: synergistic benefits of implementing the 2013 Pain, Agitation, and Delirium Guidelines in an integrated and interdisciplinary fashion.

Crit Care Med 2013 Sep;41(9 Suppl 1):S99-115

Department of Anesthesia, Stanford University School of Medicine, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0b013e3182a16ff0DOI Listing
September 2013

Pediatric delirium: monitoring and management in the pediatric intensive care unit.

Pediatr Clin North Am 2013 Jun 19;60(3):741-60. Epub 2013 Mar 19.

Department of Anesthesiology, Division of Pediatric Anesthesiology, Vanderbilt University, Nashville, TN 37232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pcl.2013.02.010DOI Listing
June 2013

The authors reply.

Crit Care Med 2013 Jun;41(6):e101-2

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0b013e31828e8d95DOI Listing
June 2013

Pediatric critical care perceptions on analgesia, sedation, and delirium.

Semin Respir Crit Care Med 2013 Apr 28;34(2):244-61. Epub 2013 May 28.

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0033-1342987DOI Listing
April 2013

Association between endothelial dysfunction and acute brain dysfunction during critical illness.

Anesthesiology 2013 Mar;118(3):631-9

Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, 1211 21st Ave. South, 526 MAB, Nashville, Tennessee 37212, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ALN.0b013e31827bd193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580006PMC
March 2013

Sedation in the intensive care setting.

Clin Pharmacol 2012 25;4:53-63. Epub 2012 Oct 25.

Vanderbilt University School of Medicine, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/CPAA.S26582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508653PMC
December 2012

Pathophysiology of acute brain dysfunction: what's the cause of all this confusion?

Curr Opin Crit Care 2012 Oct;18(5):518-26

Vanderbilt University School of Medicine, Nashville, Tennessee 37212, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MCC.0b013e328357effaDOI Listing
October 2012

Future directions of delirium research and management.

Best Pract Res Clin Anaesthesiol 2012 Sep;26(3):395-405

Department of Anesthesiology, Division of Critical Care, Vanderbilt University School of Medicine, Nashville, TN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bpa.2012.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638881PMC
September 2012