Publications by authors named "Prajwal Gurung"

50Publications

Acute IL-4 Governs Pathogenic T Cell Responses during Infection.

Immunohorizons 2020 Sep 18;4(9):546-560. Epub 2020 Sep 18.

Iowa Inflammation Program, University of Iowa, Iowa City, IA 52242;

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http://dx.doi.org/10.4049/immunohorizons.2000076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640617PMC
September 2020

Reconciling protective and pathogenic roles of the NLRP3 inflammasome in leishmaniasis.

Immunol Rev 2020 Sep 20;297(1):53-66. Epub 2020 Jun 20.

Inflammation Program, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1111/imr.12886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643606PMC
September 2020

Neutro"feels" lethal toxin.

J Leukoc Biol 2020 May 13. Epub 2020 May 13.

Inflammation Program, Infectious Diseases Division, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1002/JLB.4CE0320-101RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665983PMC
May 2020

Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.

Cell Mol Immunol 2020 Mar 19. Epub 2020 Mar 19.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41423-020-0398-7DOI Listing
March 2020

Recent Advances in Lipopolysaccharide Recognition Systems.

Int J Mol Sci 2020 Jan 7;21(2). Epub 2020 Jan 7.

Inflammation Program, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.3390/ijms21020379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013859PMC
January 2020

Leishmania major degrades murine CXCL1 - An immune evasion strategy.

PLoS Negl Trop Dis 2019 07 1;13(7):e0007533. Epub 2019 Jul 1.

Inflammation Program, University of Iowa, Iowa City, IA, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0007533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625741PMC
July 2019

Loss of RHBDF2 results in an early-onset spontaneous murine colitis.

J Leukoc Biol 2019 04 29;105(4):767-781. Epub 2019 Jan 29.

Inflammation Program, Roy J. and Lucille A. Carver College of Medicine University of Iowa, Iowa City, Iowa, USA.

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http://doi.wiley.com/10.1002/JLB.4A0718-283RR
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http://dx.doi.org/10.1002/JLB.4A0718-283RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585405PMC
April 2019

Allergic asthma: RIPK2 takes the lead.

J Leukoc Biol 2018 09 14;104(3):441-443. Epub 2018 Aug 14.

Inflammation Program, Infectious Diseases Division, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1002/JLB.3CE0718-293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223626PMC
September 2018

Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.

J Immunol 2018 09 6;201(6):1639-1644. Epub 2018 Aug 6.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and

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http://dx.doi.org/10.4049/jimmunol.1800760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483079PMC
September 2018

Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice.

Cell Death Differ 2019 03 23;26(4):741-750. Epub 2018 Jul 23.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41418-018-0159-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460383PMC
March 2019

ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.

J Clin Invest 2018 05 9;128(5):2042-2047. Epub 2018 Apr 9.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1172/JCI98446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919885PMC
May 2018

An update on cell intrinsic negative regulators of the NLRP3 inflammasome.

J Leukoc Biol 2018 Jan 26. Epub 2018 Jan 26.

Inflammation Program, University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1002/JLB.3MIR0917-350RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202258PMC
January 2018

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.

Immunity 2017 04 11;46(4):635-648. Epub 2017 Apr 11.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501252PMC
April 2017

Distinct role of IL-1β in instigating disease in Sharpin mice.

Sci Rep 2016 11 28;6:36634. Epub 2016 Nov 28.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/srep36634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125001PMC
November 2016

Autoinflammatory Skin Disorders: The Inflammasomme in Focus.

Trends Mol Med 2016 07 3;22(7):545-564. Epub 2016 Jun 3.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2016.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925313PMC
July 2016

Microbiota and caspase-1/caspase-8 regulate IL-1β-mediated bone disease.

Gut Microbes 2016 07 5;7(4):334-341. Epub 2016 May 5.

a Department of Immunology , St. Jude Children's Research Hospital , Memphis , TN , USA.

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https://www.tandfonline.com/doi/full/10.1080/19490976.2016.1
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http://dx.doi.org/10.1080/19490976.2016.1182289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988461PMC
July 2016

NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β-mediated osteomyelitis.

Proc Natl Acad Sci U S A 2016 Apr 6;113(16):4452-7. Epub 2016 Apr 6.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105

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http://dx.doi.org/10.1073/pnas.1601636113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843439PMC
April 2016

Immune responses against protozoan parasites: a focus on the emerging role of Nod-like receptors.

Cell Mol Life Sci 2016 08 31;73(16):3035-51. Epub 2016 Mar 31.

Department of Immunology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105-2794, USA.

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http://dx.doi.org/10.1007/s00018-016-2212-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956549PMC
August 2016

NLRP12 in autoimmune diseases.

Oncotarget 2015 Aug;6(24):19950-1

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652971PMC
http://dx.doi.org/10.18632/oncotarget.4585DOI Listing
August 2015

Innate immunity against Leishmania infections.

Cell Microbiol 2015 Sep 11;17(9):1286-94. Epub 2015 Aug 11.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1111/cmi.12484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698274PMC
September 2015

A20 is a regulator of necroptosis.

Nat Immunol 2015 Jun;16(6):596-7

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/ni.3174DOI Listing
June 2015

Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection.

Cell Host Microbe 2015 Mar 19;17(3):357-368. Epub 2015 Feb 19.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359672PMC
March 2015

Cutting edge: SHARPIN is required for optimal NLRP3 inflammasome activation.

J Immunol 2015 Mar 30;194(5):2064-7. Epub 2015 Jan 30.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105;

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http://dx.doi.org/10.4049/jimmunol.1402951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340749PMC
March 2015

IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis.

Nat Commun 2015 Jan 21;6:6131. Epub 2015 Jan 21.

Department of Pathology, St Jude Children's Research Hospital, 262 Danny Thomas Pl., Memphis, Tennesse 38105, USA.

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http://dx.doi.org/10.1038/ncomms7131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302761PMC
January 2015

Mitochondria: diversity in the regulation of the NLRP3 inflammasome.

Trends Mol Med 2015 Mar 27;21(3):193-201. Epub 2014 Nov 27.

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2014.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352396PMC
March 2015

Novel roles for caspase-8 in IL-1β and inflammasome regulation.

Am J Pathol 2015 Jan 1;185(1):17-25. Epub 2014 Nov 1.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.08.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278239PMC
January 2015

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation.

Nat Commun 2014 ;5:3209

1] Department of Medical Protein Research, VIB, Ghent B-9000, Belgium [2] Department of Biochemistry, Ghent University, Ghent B-9000, Belgium [3].

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http://www.nature.com/articles/ncomms4209
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http://dx.doi.org/10.1038/ncomms4209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926011PMC
October 2015

Role of inflammasomes in host defense against Citrobacter rodentium infection.

J Biol Chem 2012 May 29;287(20):16955-64. Epub 2012 Mar 29.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1074/jbc.M112.358705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351318PMC
May 2012

Systemic immunological tolerance to ocular antigens is mediated by TRAIL-expressing CD8+ T cells.

J Immunol 2011 Jan 17;186(2):791-8. Epub 2010 Dec 17.

Department of Urology, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.4049/jimmunol.1002678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075597PMC
January 2011

TRAIL-expressing CD8+ T cells mediate tolerance following soluble peptide-induced peripheral T cell deletion.

J Leukoc Biol 2010 Dec 31;88(6):1217-25. Epub 2010 Aug 31.

Department of Urology, University of Iowa, Iowa City, Iowa 52242-1089, USA.

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http://dx.doi.org/10.1189/jlb.0610343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996898PMC
December 2010

Activation-induced CD154 expression abrogates tolerance induced by apoptotic cells.

J Immunol 2009 Nov 19;183(10):6114-23. Epub 2009 Oct 19.

Department of Urology, University of Iowa, Iowa City, IA 52242-1089, USA.

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http://dx.doi.org/10.4049/jimmunol.0901676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783861PMC
November 2009

Polyclonal and antigen-specific responses of T cells and T cell subsets.

Methods Mol Biol 2008 ;447:277-94

Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1007/978-1-59745-242-7_19DOI Listing
May 2008