Prahlad T Ram

Prahlad T Ram

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Prahlad T Ram

Prahlad T Ram

Publications by authors named "Prahlad T Ram"

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40Publications

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Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.

Cell Metab 2016 11;24(5):685-700

Laboratory for Systems Biology of Human Diseases, Rice University, Houston, TX 77005, USA; Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77005, USA; Department of Bioengineering, Rice University, Houston, TX 77005, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.10.011DOI Listing
November 2016

Mapping network motif tunability and robustness in the design of synthetic signaling circuits.

PLoS One 2014 18;9(3):e91743. Epub 2014 Mar 18.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091743PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958390PMC
December 2014

Cancer Systems Biology: a peek into the future of patient care?

Nat Rev Clin Oncol 2014 Mar 4;11(3):167-76. Epub 2014 Feb 4.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1484, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/nrclinonc.2014.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321721PMC
March 2014

Platelet-derived growth factor receptor alpha (PDGFRα) targeting and relevant biomarkers in ovarian carcinoma.

Gynecol Oncol 2014 Jan 29;132(1):166-75. Epub 2013 Oct 29.

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Center for RNA Interference and Non-Coding RNA, University of Texas, Houston, TX, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2013.10.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946949PMC
January 2014

Network Motifs in JNK Signaling.

Genes Cancer 2013 Sep;4(9-10):409-13

Department of Systems Biology, UT MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1177/1947601913507577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863341PMC
September 2013

NetWalker: a contextual network analysis tool for functional genomics.

BMC Genomics 2012 Jun 25;13:282. Epub 2012 Jun 25.

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1186/1471-2164-13-282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439272PMC
June 2012

Bioinformatics and systems biology.

Mol Oncol 2012 Apr 17;6(2):147-54. Epub 2012 Feb 17.

Department of Systems Biology, Institute for Personalized Cancer Therapy, The University of Texas, MD Anderson Cancer Center, Houston, TX 77054, USA.

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http://dx.doi.org/10.1016/j.molonc.2012.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345061PMC
April 2012

Patterns of human gene expression variance show strong associations with signaling network hierarchy.

BMC Syst Biol 2010 Nov 12;4:154. Epub 2010 Nov 12.

Department of Systems Biology, The University of Texas MD Anderson Cancer Center, 7435 Fannin St, Houston, TX 77054, USA.

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http://dx.doi.org/10.1186/1752-0509-4-154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992512PMC
November 2010

Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis.

Cancer Res 2010 Sep 19;70(17):6704-14. Epub 2010 Jul 19.

Department of Systems Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932856PMC
September 2010

Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data.

PLoS Comput Biol 2010 Aug 19;6(8). Epub 2010 Aug 19.

Department of Systems Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1000889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924243PMC
August 2010

Rapidly exploring structural and dynamic properties of signaling networks using PathwayOracle.

BMC Syst Biol 2008 Aug 19;2:76. Epub 2008 Aug 19.

Department of Computer Science, Rice University, Houston, Texas, USA.

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http://dx.doi.org/10.1186/1752-0509-2-76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527501PMC
August 2008

Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R.

FASEB J 2008 May 2;22(5):1393-403. Epub 2008 Jan 2.

Department of Systems Biology, UT M.D. Anderson Cancer Center, 7435 Fannin St., Houston, TX 77054, USA.

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http://dx.doi.org/10.1096/fj.07-9100comDOI Listing
May 2008

The signaling petri net-based simulator: a non-parametric strategy for characterizing the dynamics of cell-specific signaling networks.

PLoS Comput Biol 2008 Feb 29;4(2):e1000005. Epub 2008 Feb 29.

Department of Computer Science, Rice University, Houston, Texas, USA

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http://dx.doi.org/10.1371/journal.pcbi.1000005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265486PMC
February 2008

An androgen-IL-6-Stat3 autocrine loop re-routes EGF signal in prostate cancer cells.

Mol Cell Endocrinol 2007 May 17;270(1-2):50-6. Epub 2007 Feb 17.

Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1016/j.mce.2007.02.006DOI Listing
May 2007

Hypothesis generation in signaling networks.

J Comput Biol 2006 Nov;13(9):1546-57

Department of Computer Science, Rice University, Houston, Texas 77005, USA.

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http://dx.doi.org/10.1089/cmb.2006.13.1546DOI Listing
November 2006

Exploiting the PI3K/AKT pathway for cancer drug discovery.

Nat Rev Drug Discov 2005 Dec;4(12):988-1004

Department of Molecular Therapeutics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/nrd1902DOI Listing
December 2005

The G alpha(o/i)-coupled cannabinoid receptor-mediated neurite outgrowth involves Rap regulation of Src and Stat3.

J Biol Chem 2005 Sep 26;280(39):33426-34. Epub 2005 Jul 26.

Department of Pharmacology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1074/jbc.M502812200DOI Listing
September 2005

Quantitative information management for the biochemical computation of cellular networks.

Sci STKE 2004 Aug 24;2004(248):pl11. Epub 2004 Aug 24.

Department of Physiology and Biophysics and Institute for Computational Biomedicine, Weill Medical College of Cornell University, New York, NY, 10021, USA.

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http://dx.doi.org/10.1126/stke.2482004pl11DOI Listing
August 2004

MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network.

Science 2002 Aug;297(5583):1018-23

National Center for Biological Sciences, Bangalore 560065 India.

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http://dx.doi.org/10.1126/science.1068873DOI Listing
August 2002

G protein pathways.

Science 2002 May;296(5573):1636-9

Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1126/science.1071550DOI Listing
May 2002

Overexpression of tightly regulated proteins: protein phosphatase 2A overexpression in NIH 3T3 cells.

Authors:
Prahlad T Ram

Methods Enzymol 2002 ;345:551-5

Department of Pharmacology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)45046-xDOI Listing
April 2002