Dr. Pradeepkiran Jangampalli Adi, PhD - Internal medicine/Texas Tech Health Sciences Center - Postdoc

Dr. Pradeepkiran Jangampalli Adi

PhD

Internal medicine/Texas Tech Health Sciences Center

Postdoc

Lubbock, TX | United States

Main Specialties: Biochemical Genetics, Biology, Endocrinology Diabetes & Metabolism, Neurology, Pharmacology

Additional Specialties: Bioinformatics

ORCID logohttps://orcid.org/0000-0003-4678-6443

Dr. Pradeepkiran Jangampalli Adi, PhD - Internal medicine/Texas Tech Health Sciences Center - Postdoc

Dr. Pradeepkiran Jangampalli Adi

PhD

Introduction

Currently works at the Department of Internal Medicine, Texas Tech University Health Sciences Center. Working on Alzheimer's Disease hyperphosphorylated Tau (p-Tau) interactions of AD neurons. Discovery of new lead molecules against the pathological targeted proteins in AD and other neurological disorders.

Primary Affiliation: Internal medicine/Texas Tech Health Sciences Center - Lubbock, TX , United States

Specialties:

Additional Specialties:

Research Interests:

Education

Jun 2016
Sri Venkateswara University
PhD
Jul 2007
Sri Venkateswara Institute of Medical Sciences
MSc

Experience

Oct 2016
Postdoctoral Research Associate
Sep 2014
The Research Fellowship in Sciences for meritorious students BSR

Publications

17Publications

614Reads

39Profile Views

12PubMed Central Citations

Protective Effects of BACE1 Inhibitory Ligand Molecules Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer's Disease.

Hum Mol Genet 2019 Oct 9. Epub 2019 Oct 9.

Internal Medicine Department, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, USA.

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http://dx.doi.org/10.1093/hmg/ddz227DOI Listing
October 2019
14 Reads
6.393 Impact Factor

Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer's Disease.

Cells 2019 03 19;8(3). Epub 2019 Mar 19.

Internal Medicine Department, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, USA.

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http://dx.doi.org/10.3390/cells8030260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468864PMC
March 2019
21 Reads

Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer's disease.

Drug Discov Today 2019 02 16;24(2):616-623. Epub 2018 Nov 16.

Garrison Institute on Aging, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA; Cell Biology & Biochemistry Department, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA; Pharmacology & Neuroscience Department, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA; Neurology Department, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA; Speech, Language and Hearing Sciences Departments, Texas Tech University Health Sciences Center, 3601 4th Street, MS 9424, Lubbock, TX 79430, USA; Garrison Institute on Aging, South West Campus, Texas Tech University Health Sciences Center, 6630 S. Quaker Suite E, MS 7495, Lubbock, TX 79413, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2018.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397090PMC
February 2019
32 Reads
6.691 Impact Factor

Conformational transition pathway of R308K mutant glucokinase in the presence of the glucokinase activator YNKGKA4.

FEBS Open Bio 2018 Aug 6;8(8):1202-1208. Epub 2018 Jul 6.

Garrison Institute on Aging Texas Tech University of Health Science Centre Lubbock TX USA.

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http://dx.doi.org/10.1002/2211-5463.12255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070654PMC
August 2018
17 Reads

Discovery of small molecules through pharmacophore modeling, docking and molecular dynamics simulation against Vivapain-3 (VP-3).

Heliyon 2018 May 8;4(5):e00612. Epub 2018 May 8.

Sri Venkateswara University, Tirupati, 517502, Andhra Pradesh, India.

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http://dx.doi.org/10.1016/j.heliyon.2018.e00612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944417PMC
May 2018
21 Reads

Multiplex quantification of Escherichia coli, Salmonella typhi and Vibrio cholera with three DNA targets in single reaction assay.

Microb Pathog 2017 Sep 9;110:50-55. Epub 2017 Jun 9.

Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati 517502, India.

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http://dx.doi.org/10.1016/j.micpath.2017.06.010DOI Listing
September 2017
57 Reads
2.000 Impact Factor

Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity.

Sci Rep 2017 03 27;7:45211. Epub 2017 Mar 27.

Division of Bioinformatics, Department of Zoology, Sri Venkateswara University, Tirupati, 517502, A.P., India.

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http://dx.doi.org/10.1038/srep45211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366925PMC
March 2017
22 Reads
5.080 Impact Factor

Modeling, molecular docking, probing catalytic binding mode of acetyl-CoA malate synthase G in 16M.

Biochem Biophys Rep 2016 Dec 22;8:192-199. Epub 2016 Aug 22.

Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati 517502, Andhra Pradesh, India.

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http://dx.doi.org/10.1016/j.bbrep.2016.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613768PMC
December 2016
19 Reads

Modeling, molecular dynamics, and docking assessment of transcription factor rho: a potential drug target in Brucella melitensis 16M.

Drug Des Devel Ther 2015 31;9:1897-912. Epub 2015 Mar 31.

Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati, India.

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http://dx.doi.org/10.2147/DDDT.S77020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386771PMC
September 2016
38 Reads
3 Citations
3.030 Impact Factor

Calcium, zinc and vitamin E ameliorate cadmium-induced renal oxidative damage in albino Wistar rats.

Toxicol Rep 2016 29;3:591-597. Epub 2016 Jul 29.

Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati - 517502, Andhra Pradesh, India.

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http://dx.doi.org/10.1016/j.toxrep.2016.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616016PMC
July 2016
17 Reads
1 Citation

Complete genome-wide screening and subtractive genomic approach revealed new virulence factors, potential drug targets against bio-war pathogen Brucella melitensis 16M.

Drug Des Devel Ther 2015 19;9:1691-706. Epub 2015 Mar 19.

Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati, India.

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http://dx.doi.org/10.2147/DDDT.S76948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371898PMC
May 2016
28 Reads
1 Citation
3.030 Impact Factor

CGMD: An integrated database of cancer genes and markers.

Sci Rep 2015 Jul 10;5:12035. Epub 2015 Jul 10.

Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati-517502, Andhra Pradesh, India.

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http://dx.doi.org/10.1038/srep12035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498195PMC
July 2015
158 Reads
1 Citation
5.080 Impact Factor

Comparison and correlation of Simple Sequence Repeats distribution in genomes of Brucella species.

Bioinformation 2011 26;6(5):179-82. Epub 2011 May 26.

Division of Animal Biotechnology, Department of Zoology, S. V. University, Tirupati-517502, Andhra Pradesh, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124796PMC
http://dx.doi.org/10.6026/97320630006179DOI Listing
July 2011
17 Reads
1 Citation

Top co-authors

Matcha Bhaskar
Matcha Bhaskar

Sri Venkateswara University

5
Arubala P Reddy
Arubala P Reddy

Oregon National Primate Research Center

5
Ramesh Kandimalla
Ramesh Kandimalla

Postgraduate Institute of Medical Education and Research

4
Maria Manczak
Maria Manczak

Garrison Institute on Aging

4
Bhaskar Matcha
Bhaskar Matcha

Sri Venkateswara University

3
Subodh Kumar
Subodh Kumar

Texas Tech University Health Sciences Center

3
Xiangling Yin
Xiangling Yin

Garrison Institute on Aging

3
Yellapu Nanda Kumar
Yellapu Nanda Kumar

Sri Venkateswara University

3