Poul H Sorensen

Poul H Sorensen

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Poul H Sorensen

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A Standardized and Reproducible Proteomics Protocol for Bottom-Up Quantitative Analysis of Protein Samples Using SP3 and Mass Spectrometry.

Methods Mol Biol 2019 ;1959:65-87

Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/978-1-4939-9164-8_5DOI Listing
July 2019

Methods for Identifying Patients with Tropomyosin Receptor Kinase (TRK) Fusion Cancer.

Pathol Oncol Res 2019 Jun 29. Epub 2019 Jun 29.

British Columbia Cancer Agency, Provincial Health Services Authority, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s12253-019-00685-2DOI Listing
June 2019

Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation.

Commun Biol 2019 3;2:165. Epub 2019 May 3.

1Department of Molecular Oncology, BC Cancer, part of the Provincial Health Services Authority, 675 West 10th Avenue, Vancouver, BC V5Z 1L3 Canada.

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http://dx.doi.org/10.1038/s42003-019-0391-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499833PMC
May 2019

Stress-induced tunneling nanotubes support treatment adaptation in prostate cancer.

Sci Rep 2019 May 24;9(1):7826. Epub 2019 May 24.

The Vancouver Prostate Centre, Department of Urological Sciences, University of British Columbia, 2775 Laurel Street, Vancouver, British Columbia, V6H 3Z6, Canada.

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http://www.nature.com/articles/s41598-019-44346-5
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http://dx.doi.org/10.1038/s41598-019-44346-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534589PMC
May 2019

Translational control in brain pathologies: biological significance and therapeutic opportunities.

Acta Neuropathol 2019 Apr 9;137(4):535-555. Epub 2019 Feb 9.

Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, V5Z 1L3, Canada.

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http://dx.doi.org/10.1007/s00401-019-01971-8DOI Listing
April 2019

RawTools: Rapid and Dynamic Interrogation of Orbitrap Data Files for Mass Spectrometer System Management.

J Proteome Res 2019 02 3;18(2):700-708. Epub 2018 Dec 3.

Canada's Michael Smith Genome Sciences Centre , British Columbia Cancer Agency , Vancouver , British Columbia V5Z 1L3 , Canada.

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http://dx.doi.org/10.1021/acs.jproteome.8b00721DOI Listing
February 2019

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments.

Nat Protoc 2019 01;14(1):68-85

Division Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://www.nature.com/articles/s41596-018-0082-x
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http://dx.doi.org/10.1038/s41596-018-0082-xDOI Listing
January 2019

HACE1 is a potential tumor suppressor in osteosarcoma.

Cell Death Dis 2019 01 8;10(1):21. Epub 2019 Jan 8.

Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1038/s41419-018-1276-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325116PMC
January 2019

Ewing sarcoma.

Nat Rev Dis Primers 2018 07 5;4(1). Epub 2018 Jul 5.

German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41572-018-0003-xDOI Listing
July 2018

Translational control of aberrant stress responses as a hallmark of cancer.

J Pathol 2018 04 20;244(5):650-666. Epub 2018 Feb 20.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1002/path.5030DOI Listing
April 2018

Novel identification of STAT1 as a crucial mediator of ETV6-NTRK3-induced tumorigenesis.

Oncogene 2018 04 2;37(17):2270-2284. Epub 2018 Feb 2.

Precision Medicine Research Center, Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Gyeonggi-do, 16229, Republic of Korea.

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http://dx.doi.org/10.1038/s41388-017-0102-2DOI Listing
April 2018

Extending the Compatibility of the SP3 Paramagnetic Bead Processing Approach for Proteomics.

J Proteome Res 2018 04 27;17(4):1730-1740. Epub 2018 Mar 27.

Canada's Michael Smith Genome Sciences Centre , British Columbia Cancer Agency , Vancouver , British Columbia V5Z 1L3 , Canada.

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http://dx.doi.org/10.1021/acs.jproteome.7b00913DOI Listing
April 2018

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Nat Commun 2018 04 30;9(1):1734. Epub 2018 Apr 30.

Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA.

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http://dx.doi.org/10.1038/s41467-018-04092-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928080PMC
April 2018

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay.

J Vis Exp 2018 03 12(133). Epub 2018 Mar 12.

BC Cancer Agency, Provincial Health Services Authority; Department of Pathology and Laboratory Medicine, University of British Columbia;

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http://dx.doi.org/10.3791/56332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931694PMC
March 2018

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.

Cell 2018 02;172(5):1050-1062.e14

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346737PMC
February 2018

The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.

Mol Oncol 2017 09 21;11(9):1288-1301. Epub 2017 Aug 21.

Laboratory for Functional Genomics and Transplantation Biology, Children's Cancer Research Center and Department of Pediatrics, Klinikum rechts der Isar, Technische Universität München, Comprehensive Cancer Center Munich (CCCM), German Translational Cancer Research Consortium (DKTK), Munich, Germany.

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http://dx.doi.org/10.1002/1878-0261.12057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579336PMC
September 2017

eEF2K protects MYCN-amplified cells from starvation.

Cell Cycle 2017 09 2;16(18):1633-1634. Epub 2017 Aug 2.

a Department of Molecular Oncology , British Columbia Cancer Research Centre , Vancouver , BC , Canada.

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http://dx.doi.org/10.1080/15384101.2017.1355180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602424PMC
September 2017

Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.

Sci Rep 2017 03 20;7:44779. Epub 2017 Mar 20.

Inserm, U1065, C3M, Team Bacterial Toxins in Host-Pathogens Interactions France, Equipe labellisée la ligue contre le cancer, Nice 06204, France.

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http://dx.doi.org/10.1038/srep44779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357957PMC
March 2017

eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.

Acta Neuropathol 2017 01 17;133(1):101-119. Epub 2016 Oct 17.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1007/s00401-016-1634-1DOI Listing
January 2017

miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma.

Carcinogenesis 2016 09 4;37(9):858-869. Epub 2016 Aug 4.

The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area , Shantou University Medical College , Shantou , Guangdong 515041 , China.

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http://carcin.oxfordjournals.org/content/early/2016/08/19/ca
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http://dx.doi.org/10.1093/carcin/bgw079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008252PMC
September 2016

Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine.

Sci Rep 2016 09 8;6:32606. Epub 2016 Sep 8.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V5Z 1L3 Canada.

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http://dx.doi.org/10.1038/srep32606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015067PMC
September 2016

An Aqueous Extract of Marine Microalgae Exhibits Antimetastatic Activity through Preferential Killing of Suspended Cancer Cells and Anticolony Forming Activity.

Evid Based Complement Alternat Med 2016 31;2016:9730654. Epub 2016 Aug 31.

Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada; Department of Experimental Therapeutics, British Columbia Cancer Research Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1155/2016/9730654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021869PMC
September 2016

ETV6-NTRK3 Is Expressed in a Subset of ALK-Negative Inflammatory Myofibroblastic Tumors.

Am J Surg Pathol 2016 08;40(8):1051-61

*Department of Pathology, Vancouver General Hospital §Genome Sciences Center ∥British Columbia Cancer Agency ¶British Columbia Children's Hospital #Department of Pathology, University of British Columbia, Vancouver, BC **Department of Pathology, Royal Alexandra Hospital, Edmonton, AB, Canada †Department of Pathology, King Abdulaziz Medical City, Riyadh, Saudi Arabia ‡Department of Pathology, Kuwait University, Kuwait.

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http://dx.doi.org/10.1097/PAS.0000000000000677DOI Listing
August 2016

Twenty Years on: What Do We Really Know about Ewing Sarcoma and What Is the Path Forward?

Crit Rev Oncog 2015 ;20(3-4):155-71

Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671490PMC
June 2016

Stress-mediated translational control in cancer cells.

Biochim Biophys Acta 2015 Jul 10;1849(7):845-60. Epub 2014 Nov 10.

Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia V5Z 1L4, Canada; Department of Pathology, University of British Columbia, Vancouver, British Columbia V6T 2B5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2014.11.002DOI Listing
July 2015

Direct intracerebral delivery of a miR-33 antisense oligonucleotide into mouse brain increases brain ABCA1 expression. [Corrected].

Neurosci Lett 2015 Jun 6;598:66-72. Epub 2015 May 6.

Centre for Molecular Medicine and Therapeutics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043940150035
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http://dx.doi.org/10.1016/j.neulet.2015.05.007DOI Listing
June 2015

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis.

Cancer Cell 2015 May;27(5):682-97

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 2B5, Canada; Department of Molecular Oncology, British Columbia Cancer Research Center, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.04.003DOI Listing
May 2015

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1.

J Cell Biol 2015 Mar 23;208(7):913-29. Epub 2015 Mar 23.

Department of Pathology and Laboratory Medicine and Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada Department of Pathology and Laboratory Medicine and Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia V5Z 1L3, Canada

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http://dx.doi.org/10.1083/jcb.201411047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384734PMC
March 2015

Epigenetic reprogramming and re-differentiation of a Ewing sarcoma cell line.

Front Cell Dev Biol 2015 9;3:15. Epub 2015 Mar 9.

Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University Baltimore, MD, USA ; Ron Matricaria Institute of Molecular Medicine, Phoenix Children's Hospital, University of Arizona Phoenix, AZ, USA.

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http://journal.frontiersin.org/Article/10.3389/fcell.2015.00
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http://dx.doi.org/10.3389/fcell.2015.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353378PMC
March 2015

How does oncogene transformation render tumor cells hypersensitive to nutrient deprivation?

Bioessays 2014 Nov 22;36(11):1082-90. Epub 2014 Sep 22.

Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada; Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/bies.201400085DOI Listing
November 2014

ChildSeq-RNA: A next-generation sequencing-based diagnostic assay to identify known fusion transcripts in childhood sarcomas.

J Mol Diagn 2014 May 8;16(3):361-70. Epub 2014 Feb 8.

Department of Molecular Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15251578140000
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http://dx.doi.org/10.1016/j.jmoldx.2014.01.002DOI Listing
May 2014

DrugPath: a database for academic investigators to match oncology molecular targets with drugs in development.

Cancer Chemother Pharmacol 2014 May 25;73(5):1089-93. Epub 2014 Mar 25.

Cancer Center and Departments of Cell Biology and Biochemistry, Pediatrics, and Internal Medicine, School of Medicine, Texas Tech University Health Sciences Center, 3601 4th St, STOP 9445, Lubbock, TX, 79430, USA.

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http://link.springer.com/10.1007/s00280-014-2433-9
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http://dx.doi.org/10.1007/s00280-014-2433-9DOI Listing
May 2014

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.

Nat Commun 2014 Mar 11;5:3430. Epub 2014 Mar 11.

1] University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7 [2] Heart and Stroke/Richard Lewar Centre of Excellent for Cardiovascular Research, University of Toronto and Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada M5G 2C4 [3] Department of Physiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [4] Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1038/ncomms4430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959209PMC
March 2014

Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation.

Cancer Res 2014 Feb 12;74(3):829-39. Epub 2013 Dec 12.

Authors' Affiliations: Department of Cancer Biology; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania; Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China; and Department of Molecular Oncology, British Columbia Cancer Research Center, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933065PMC
February 2014

[Surviving nutrient deprivation by restraining translation elongation: biological function of the eEF2 kinase].

Med Sci (Paris) 2013 Nov 20;29(11):951-3. Epub 2013 Nov 20.

Département d'oncologie moléculaire, Centre de recherche contre le cancer de Colombie Britannique et département de pathologie, Université de Colombie Britannique, 675 West 10th avenue, V5Z1L3 Vancouver, Canada.

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http://dx.doi.org/10.1051/medsci/20132911007DOI Listing
November 2013

Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation.

J Biol Chem 2013 Sep 24;288(39):27940-50. Epub 2013 Jun 24.

From the Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 2B5, Canada.

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http://dx.doi.org/10.1074/jbc.M113.475301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784708PMC
September 2013

TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis.

Apoptosis 2013 Mar;18(3):324-36

Department of Cell Biology, University of Geneva, Sciences III, 30 quai Ernest Ansermet, 1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1007/s10495-012-0782-6DOI Listing
March 2013

Expression and stability of hypoxia inducible factor 1α in osteosarcoma.

Pediatr Blood Cancer 2012 Dec 27;59(7):1215-22. Epub 2012 Apr 27.

Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://doi.wiley.com/10.1002/pbc.24191
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http://dx.doi.org/10.1002/pbc.24191DOI Listing
December 2012

IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors.

Sci Signal 2012 Dec 18;5(255):ra92. Epub 2012 Dec 18.

Biological Sciences Platform, Sunnybrook Research Institute and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M4N 3M5, Canada.

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http://dx.doi.org/10.1126/scisignal.2003184DOI Listing
December 2012

On translational regulation and EMT.

Semin Cancer Biol 2012 Oct 23;22(5-6):437-45. Epub 2012 Apr 23.

Institute of Protein Research, Pushchino, Moscow Region 142290, Russian Federation.

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http://dx.doi.org/10.1016/j.semcancer.2012.04.007DOI Listing
October 2012

Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study.

J Pathol 2012 Sep 2;228(1):119-30. Epub 2012 Jul 2.

Department of Pathology, Northwestern University Feinberg School of Medicine and the Robert H Lurie Comprehensive Cancer Center, Chicago, IL, USA.

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http://dx.doi.org/10.1002/path.4010DOI Listing
September 2012

LEDGF (p75) promotes DNA-end resection and homologous recombination.

Nat Struct Mol Biol 2012 Aug 8;19(8):803-10. Epub 2012 Jul 8.

Cell Death and Metabolism, Danish Cancer Society Research Center, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nsmb.2314DOI Listing
August 2012

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://is.muni.cz/repo/990835/nature11327.pdf
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http://www.nature.com/doifinder/10.1038/nature11327
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http://dx.doi.org/10.1038/nature11327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683624PMC
August 2012

Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy.

Expert Opin Ther Targets 2012 Jan 12;16(1):33-48. Epub 2012 Jan 12.

British Columbia Cancer Research Centre , Department of Molecular Oncology, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1517/14728222.2011.638626DOI Listing
January 2012

A possible role for long non-coding RNA in modulating signaling pathways.

Med Hypotheses 2011 Dec 7;77(6):962-5. Epub 2011 Sep 7.

Department of Molecular Oncology, BC Cancer Research Center, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.mehy.2011.08.020DOI Listing
December 2011

Clusterin is a critical downstream mediator of stress-induced YB-1 transactivation in prostate cancer.

Mol Cancer Res 2011 Dec 10;9(12):1755-66. Epub 2011 Oct 10.

The Vancouver Prostate Centre and Department of Urologic Sciences, University of British Columbia, Vancouver, BC V6H 3Z6, Canada.

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http://mcr.aacrjournals.org/content/early/2011/10/07/1541-77
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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-11
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http://dx.doi.org/10.1158/1541-7786.MCR-11-0379DOI Listing
December 2011

ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway.

Cancer Res 2011 Feb 9;71(3):1060-70. Epub 2010 Dec 9.

Department of Molecular Oncology, BC Cancer Research Center, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3096DOI Listing
February 2011

Ubiquitous expression of the monomeric red fluorescent protein mCherry in transgenic mice.

Genesis 2010 Dec 19;48(12):723-9. Epub 2010 Nov 19.

British Columbia Cancer Research Centre, Vancouver BC, V5Z 1L3, Canada.

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http://dx.doi.org/10.1002/dvg.20677DOI Listing
December 2010

Understanding micrometastatic disease and Anoikis resistance in ewing family of tumors and osteosarcoma.

Oncologist 2010 17;15(6):627-35. Epub 2010 May 17.

UCL Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, U.K.

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http://dx.doi.org/10.1634/theoncologist.2010-0093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227993PMC
October 2010

Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells.

Mol Cancer Ther 2010 May 27;9(5):1396-407. Epub 2010 Apr 27.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-0604DOI Listing
May 2010

Reduced proliferation and enhanced migration: two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1.

Cell Cycle 2009 Sep 16;8(18):2901-6. Epub 2009 Sep 16.

Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, CA.

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http://dx.doi.org/10.4161/cc.8.18.9537DOI Listing
September 2009

Sarcomas with spindle cell morphology.

Semin Oncol 2009 Aug;36(4):324-37

Department of Anatomic Pathology, IRCCS Foundation, Istituto Nazionale Tumori, Milan, Italy.

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http://dx.doi.org/10.1053/j.seminoncol.2009.06.007DOI Listing
August 2009

Small round cell sarcomas.

Semin Oncol 2009 Aug;36(4):338-46

Huntsman Cancer Institute, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2009.06.006DOI Listing
August 2009

Characterization of NKIP: a novel, Na+/K+-ATPase interacting protein mediates neural differentiation and apoptosis.

Exp Cell Res 2008 Feb 24;314(3):463-77. Epub 2007 Nov 24.

Department of Clinical Pharmacology, Section of Experimental Oncology/Molecular Pharmacology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.yexcr.2007.11.013DOI Listing
February 2008

Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV.

J Mol Diagn 2007 Sep 9;9(4):459-63. Epub 2007 Jul 9.

Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, 600 W. 10th Ave., Vancouver, BC, Canada, V5Z 4E6.

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http://dx.doi.org/10.2353/jmoldx.2007.070009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1975098PMC
September 2007

The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.

Nat Med 2007 Sep 12;13(9):1060-9. Epub 2007 Aug 12.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Dr. Bohrgasse 3, 1030 Vienna, Austria.

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http://dx.doi.org/10.1038/nm1621DOI Listing
September 2007

Cellular transformation and activation of the phosphoinositide-3-kinase-Akt cascade by the ETV6-NTRK3 chimeric tyrosine kinase requires c-Src.

Cancer Res 2007 Apr;67(7):3192-200

Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3526DOI Listing
April 2007

Y-box binding protein 1: providing a new angle on translational regulation.

Cell Cycle 2006 Jun 1;5(11):1143-7. Epub 2006 Jun 1.

Department of Pathology, Child and Family Research Institute, University of British Columbia, Canada.

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https://www.tandfonline.com/doi/full/10.4161/cc.5.11.2784
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http://dx.doi.org/10.4161/cc.5.11.2784DOI Listing
June 2006