Poul H Jensen

Poul H Jensen

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Poul H Jensen

Poul H Jensen

Publications by authors named "Poul H Jensen"

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Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease.

Alzheimers Dement 2018 08 28;14(8):1052-1062. Epub 2018 Mar 28.

Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA; Department of Pathology, Peking University Health Science Centre and Third Hospital, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097943PMC
August 2018

Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation.

J Vis Exp 2018 05 3(135). Epub 2018 May 3.

DANDRITE - Danish Research Institute of Translational Neuroscience, Dept. of Biomedicine, Aarhus University;

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http://dx.doi.org/10.3791/57056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101095PMC
May 2018

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

Neurology 2018 01 13;90(2):74-82. Epub 2017 Dec 13.

From Muhammad Ali Parkinson Center (R.R.W.), Barrow Neurological Institute, Phoenix, AZ; Department of Neurology (F.K., G.K.W., W.P., K.S., N.S.), Medical University Innsbruck, Austria; National Institute of Neurological Disorders and Stroke (W.R.G., W.J.K.), NIH, Bethesda, MD; Department of Neurology (P.A.L.), Mayo Clinic, Rochester, MN; Brain and Mind Centre (G.H.), Sydney Medical School, the University of Sydney; UNSW Medicine & Neuroscience Research Australia (G.H.), Sydney; Queen Square Brain Bank (J.H.), UCL Institute of Neurology (N.P.Q.), London, UK; UPS, INSERM, and CHU de Toulouse (O.R.), University de Toulouse; Centre de Référence Maladie Rare contre l'AMS (O.R.), Centre d'Investigation Clinique CIC1436, Départments de Pharmacologie Clinique et de Neurosciences, NeuroToul/COEN Center of Excellence in Neurodegeneration, Toulouse, France; Department of Pathology & Laboratory Medicine (L.M.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Center for Neurosciences (D.E.), The Feinstein Institute for Medical Research, Manhasset, NY; The Multiple System Atrophy (MSA) Coalition, Inc. (P. B., J.B., P.F., L.K., C.L., C.R., S.S.), Charlotte, NC; Cleveland Clinic Lou Ruvo Center for Brain Health (J.L.C.), Las Vegas, NV; Medical Affairs (V.A.), Teva Pharmaceuticals, Frazer, PA; Department of Neurology (G.B.), David Geffen School of Medicine, Brain Research Institute, and Molecular Biology Institute, University of California at Los Angeles; Institute of Neurology (D.J.B.), University of Newcastle upon Tyne, UK; Van Andel Research Institute (P. Brundin), Center for Neurodegenerative Science, Grand Rapids, MI; Center for Neurological Restoration (H.F.), Cleveland Clinic, OH; Defeat MSA (P.F.); MSA Shoe Charity (P.F., C.R.), Saint Clair Shores, MI; Department of Neurology (R.F.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; Department of Neurodegenerative Diseases (T.G.), Hertie Institute of Clinical Brain Research, University of Tübingen; German Center for Neurodegenerative Diseases (DZNE) (T.G.), Tübingen, Germany; Lundbeck LLC (A.H.), Deerfield, IL; German Center for Neurodegenerative Diseases (DZNE) (G.U.H.), Munich; Department of Neurology (G.U.H.), Technical University of Munich, Germany; Neurogenomics Division (M.J.H.), The Translational Genomics Research Institute, Phoenix, AZ; Dandrite & Department of Biomedicine (P.H.J.), Aarhus University, Denmark; Quanterix (A.J.), Lexington, MA; Department of Neurology (U.J.K.), Columbia University Medical Center; Department of Neurology (H.K.), New York University School of Medicine, New York; Whitehead Institute for Biomedical Research (V.K.), Cambridge; Ann Romney Center for Neurologic Disease (V.K.), Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston; Harvard Stem Cell Institute (V.K.), Cambridge, MA; Department of Neurology (T.K.), University of Bonn; German Center for Neurodegenerative Diseases (DZNE) (T.K.), Bonn, Germany; Brain and Mind Centre (W.S.K.), Sydney Medical School, University of Sydney, Australia; Department of Neurology (P.L.), Henry Ford Hospital; Department of Neurology (P.L.), Wayne State University School of Medicine, Detroit, MI; Division of Neurosciences (E.M.), National Institute on Aging/NIH, Bethesda, MD; Centre de Référence Maladie Rare AMS (W.M.), Hôpital Pellegrin, CHU de Bordeaux; Université de Bordeaux (W.M.), Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux; Paris Saclay Institute of Neuroscience (R.M.), CNRS, Gif-sur-Yvette, France; Genentech Inc. (S.O.), South San Francisco; Cedars-Sinai Medical Center (S.P.), Los Angeles, CA; Department of Neurology (D.R.), Vanderbilt University Medical Center, Nashville, TN; MSA NJ (C.R.), Howell, NJ; Prothena Biosciences (D.S.), South San Francisco, CA; Division of Neurology (M.S.), Department of Medicine, The Ottawa Hospital, Canada; Department of Neurology (J.D.S.), Massachusetts General Hospital, Harvard Medical School, Boston, MA; Cure MSA Foundation (L.S.), Fremont, CA; Avid Radiopharmaceuticals (A.S.), Philadelphia, PA; Department of Neurological Sciences (G.T.S.), Rush University Medical Center, Chicago, IL; Department of Neurology (S.T.), Graduate School of Medicine, Tokyo University, Tokyo, Japan; and University of Washington (J.Z.), Seattle. W.R.G. is currently affiliated with Janssen Research and Development, Titusville, NJ.

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http://dx.doi.org/10.1212/WNL.0000000000004798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772155PMC
January 2018

Polo-like kinase 2 modulates α-synuclein protein levels by regulating its mRNA production.

Neurobiol Dis 2017 Oct 23;106:49-62. Epub 2017 Jun 23.

Aarhus University, DANDRITE - Danish Research Institute of Translational Neuroscience, Dept. of Biomedicine, Ole Worms Allé 3, DK-8000 Aarhus, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2017.06.014DOI Listing
October 2017

Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry.

Biochemistry 2013 Dec 11;52(51):9097-103. Epub 2013 Dec 11.

Department of Biochemistry and Molecular Biology, University of Southern Denmark , 5230 Odense M, Denmark.

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http://dx.doi.org/10.1021/bi4009193DOI Listing
December 2013

Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion.

J Neurochem 2013 Apr 15;125(2):314-27. Epub 2013 Jan 15.

Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, Faculty of Medicine, University of Tübingen, Germany.

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http://dx.doi.org/10.1111/jnc.12126DOI Listing
April 2013

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.

J Neurosci 2012 Mar;32(10):3301-5

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5368-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548448PMC
March 2012

Incipient intranuclear inclusion body disease in a 78-year-old woman.

Neuropathology 2011 Apr;31(2):188-93

Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2010.01150.xDOI Listing
April 2011

Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology.

Eur J Neurosci 2010 Aug;32(3):409-22

Brain Repair and Imaging in Neural Systems, Department of Experimental Medical Science, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1460-9568.2010.07284.xDOI Listing
August 2010

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

Brain 2009 Apr 20;132(Pt 4):1093-101. Epub 2009 Jan 20.

Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1093/brain/awn349DOI Listing
April 2009

P25alpha/Tubulin polymerization promoting protein expression by myelinating oligodendrocytes of the developing rat brain.

J Neurochem 2006 Oct 31;99(1):333-42. Epub 2006 Jul 31.

Institute of Medical Anatomy, University of Copenhagen, Copenhagen, Denmark.

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http://doi.wiley.com/10.1111/j.1471-4159.2006.04073.x
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http://dx.doi.org/10.1111/j.1471-4159.2006.04073.xDOI Listing
October 2006

Cellular parkin mutants are soluble under non-stress conditions.

Neuroreport 2006 Jul;17(11):1205-8

Institutes of Medical Biochemistry, University of Aarhus, Aarhus, Denmark.

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http://dx.doi.org/10.1097/01.wnr.0000230511.63220.e3DOI Listing
July 2006

Association of alpha-synuclein and mutants with lipid membranes: spin-label ESR and polarized IR.

Biochemistry 2006 Mar;45(10):3386-95

Max-Planck-Institut für biophysikalische Chemie, Abt. Spektroskopie, 37070 Göttingen, Germany.

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http://dx.doi.org/10.1021/bi052344dDOI Listing
March 2006

Oligodendrocytes within astrocytes ("emperipolesis") in the cerebral white matter in hepatic and hypoglycemic encephalopathy.

Neuropathology 2006 Feb;26(1):62-5

Department of Neuropathology, Institute of Brain Science, Hirosaki University School of Medicine, Hirosaki, Japan.

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February 2006

Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

Brain 2005 Nov 6;128(Pt 11):2654-64. Epub 2005 Jul 6.

Prince of Wales Medical Research Institute and the University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1093/brain/awh584DOI Listing
November 2005

p25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry.

Protein Sci 2005 Jun 9;14(6):1396-409. Epub 2005 May 9.

Dept. of Life Sciences, Aalborg University, Sohngaardsholmsvej 49, DK-9000 Aalborg, Denmark.

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http://dx.doi.org/10.1110/ps.041285605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253386PMC
June 2005

Proteasomal inhibition by alpha-synuclein filaments and oligomers.

J Biol Chem 2004 Mar 7;279(13):12924-34. Epub 2004 Jan 7.

Department of Medical Biochemistry, University of Aarhus, 8000 Aarhus-C, Denmark.

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http://dx.doi.org/10.1074/jbc.M306390200DOI Listing
March 2004

Absence of prostate apoptosis response-4 protein in substantia nigra of Parkinson's disease autopsies.

Acta Neuropathol 2004 Jan 17;107(1):23-6. Epub 2003 Sep 17.

Department of Medical Anatomy, section B, The Panum Institute, University of Copenhagen, 2200, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00401-003-0769-zDOI Listing
January 2004

Alpha-synuclein association with phosphatidylglycerol probed by lipid spin labels.

Biochemistry 2003 Nov;42(44):12919-26

Max-Planck-Institut für biophysikalische Chemie, Abt. Spektroskopie, 37070 Göttingen, Germany.

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http://dx.doi.org/10.1021/bi035048eDOI Listing
November 2003

Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease?

Proc Natl Acad Sci U S A 2002 Nov 1;99(23):15042-7. Epub 2002 Nov 1.

Department of Experimental Neurology, Max-Planck-Institute for Neurological Research, 50931 Cologne, Germany.

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http://dx.doi.org/10.1073/pnas.232588799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137541PMC
November 2002