Publications by authors named "Poornima Mahavadi"

30Publications

Defective BACH1/HO-1 regulatory circuits in cystic fibrosis bronchial epithelial cells.

J Cyst Fibros 2020 Jun 11. Epub 2020 Jun 11.

Department of Internal Medicine, Justus-Liebig University, Giessen, Germany; University of Giessen and Marburg Lung Center (UGMLC), Member of the German Centre for Lung Research (DZL), Giessen, Germany; Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany.

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http://dx.doi.org/10.1016/j.jcf.2020.05.006DOI Listing
June 2020

Hermansky-Pudlak syndrome type 2 manifests with fibrosing lung disease early in childhood.

Orphanet J Rare Dis 2018 03 27;13(1):42. Epub 2018 Mar 27.

Ludwig-Maximilians University, Dr von Haunersches Kinderspital, German Center for Lung Research (DZL), Lindwurmstr. 4, 80337, Munich, Germany.

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http://dx.doi.org/10.1186/s13023-018-0780-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870397PMC
March 2018

Resistance to apoptosis and autophagy leads to enhanced survival in Sertoli cells.

Mol Hum Reprod 2017 06;23(6):370-380

Department of Anatomy and Cell Biology, Justus-Liebig University, Aulweg 123, Giessen 35392, Germany.

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http://dx.doi.org/10.1093/molehr/gax022DOI Listing
June 2017

Regulation of macroautophagy in amiodarone-induced pulmonary fibrosis.

J Pathol Clin Res 2015 Oct 3;1(4):252-63. Epub 2015 Jun 3.

Department of Internal MedicineJustus-Liebig-UniversityGiessenGermany; Universities of Giessen and Marburg Lung Center (UGMLC), German Center for Lung Research (DZL)GiessenGermany; Member of the European IPF Network; Lung Clinic Waldhof-ElgershausenGreifensteinGermany.

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http://dx.doi.org/10.1002/cjp2.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939895PMC
October 2015

MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.

Am J Physiol Lung Cell Mol Physiol 2016 Mar 30;310(6):L519-31. Epub 2015 Dec 30.

Department of Internal Medicine, Justus-Liebig University, Giessen, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Centre for Lung Research (DZL), Giessen, Germany;

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http://dx.doi.org/10.1152/ajplung.00213.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888554PMC
March 2016

A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation.

J Cyst Fibros 2016 05 30;15(3):325-31. Epub 2015 Oct 30.

Department of Pulmonary Medicine, Philipps-University Marburg, Baldingerstrasse 1, Marburg 35043, Germany; Asklepios Fachkliniken München-Gauting, Gauting, Germany; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jcf.2015.10.008DOI Listing
May 2016

Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis.

Thorax 2015 Nov 10;70(11):1022-32. Epub 2015 Sep 10.

Department of Internal Medicine, Justus-Liebig-University Giessen, Giessen, Germany Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Excellence Cluster Cardio-Pulmonary System (ECCPS), Giessen, Germany Agaplesion Lung Clinic Waldhof Elgershausen, Greifenstein, Germany European IPF Network and European IPF Registry.

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http://dx.doi.org/10.1136/thoraxjnl-2014-206411DOI Listing
November 2015

Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model.

Am J Physiol Lung Cell Mol Physiol 2015 Jul 8;309(1):L63-75. Epub 2015 May 8.

Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Hannover, Germany; Member of the German Center for Lung Research (DZL), Germany;

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http://dx.doi.org/10.1152/ajplung.00279.2014DOI Listing
July 2015

Impaired TLR4 and HIF expression in cystic fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro.

Am J Physiol Lung Cell Mol Physiol 2014 Nov 19;307(10):L791-9. Epub 2014 Sep 19.

Department of Medicine, Pulmonary Critical Care Philipps University, Marburg, Germany; Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany; Member of the German Center for Lung Research (DZL); Pneumology, Asklepios Fachkliniken München-Gauting, Germany; Comprehensive Pneumology Center (CPC), Helmholtz Zentrum, Munich, Germany

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http://dx.doi.org/10.1152/ajplung.00167.2014DOI Listing
November 2014

Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis.

Toxicol Sci 2014 Nov 27;142(1):285-97. Epub 2014 Aug 27.

Department of Internal Medicine, Justus-Liebig-University Giessen, Germany Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany Member of the European IPF Network Lung Clinic Waldhof-Elgershausen, Greifenstein, Germany.

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http://dx.doi.org/10.1093/toxsci/kfu177DOI Listing
November 2014

Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis.

Eur Respir Rev 2012 Jun;21(124):152-60

Universities of Giessen and Marburg Lung Center, Dept of Internal Medicine II, German Center for Lung Research, Germany.

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http://err.ersjournals.com/content/errev/21/124/152.full.pdf
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http://err.ersjournals.com/cgi/doi/10.1183/09059180.00001012
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http://dx.doi.org/10.1183/09059180.00001012DOI Listing
June 2012

Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia.

Am J Respir Crit Care Med 2010 Jul 8;182(2):207-19. Epub 2010 Apr 8.

Department of Internal Medicine II, University of Giessen Lung Center (UGLC), Klinikstrasse 36, 35392 Giessen, Germany.

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http://dx.doi.org/10.1164/rccm.200909-1414OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913235PMC
July 2010