Publications by authors named "Pooneh Mokarram"

50Publications

The ER Stress/UPR Axis in Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.

Life (Basel) 2020 Dec 22;11(1). Epub 2020 Dec 22.

Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.

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December 2020

Design and characterization of a recombinant immunotoxin for targeted therapy of breast cancer cells: In vitro and in silico analyses.

Life Sci 2021 Jan 7;265:118866. Epub 2020 Dec 7.

Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

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January 2021

Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells.

Cells 2020 10 22;9(11). Epub 2020 Oct 22.

Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.

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October 2020

Rapid and Cost-Effective RNA Extraction of Rat Pancreatic Tissue.

J Vis Exp 2020 09 19(163). Epub 2020 Sep 19.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences; Autophagy Research Center, School of Medicine, Shiraz University of Medical Sciences;

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September 2020

Mechanisms Targeting the Unfolded Protein Response in Asthma.

Am J Respir Cell Mol Biol 2021 Jan;64(1):29-38

Lung Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, School of Medicine, University of California, Davis, Davis, California; and.

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January 2021

Vitamin D Receptor Gene Polymorphisms and the Risk of Metabolic Syndrome (MetS): A Meta-Analysis.

Endocr Metab Immune Disord Drug Targets 2020 Aug 4. Epub 2020 Aug 4.

Department of immunology, school of public health, Tehran university of medical sciences, Tehran. Iran.

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August 2020

The effects of 17 Beta-Estradiol primed mesenchymal stem cells on the biology of co-cultured neutrophil.

Int Immunopharmacol 2020 Jul 15;84:106602. Epub 2020 May 15.

Autophagy Research Center, Department of Biochemistry, Shiraz University of Medical Sciences, Shiraz, Iran.

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July 2020

Altered ARID1A expression in colorectal cancer.

BMC Cancer 2020 Apr 25;20(1):350. Epub 2020 Apr 25.

Cancer Center and Department of Medicine, Howard University, College of Medicine, 2041 Georgia Avenue, N.W., Washington, D.C., 20060, USA.

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April 2020

The role of radiation induced oxidative stress as a regulator of radio-adaptive responses.

Int J Radiat Biol 2020 05 7;96(5):561-576. Epub 2020 Feb 7.

Department of Medical Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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May 2020

KRAS mutation and abnormal expression of Cripto-1 as two potential candidate biomarkers for detection of colorectal cancer development.

J Cell Biochem 2020 Apr 6;121(4):2901-2908. Epub 2019 Nov 6.

Colorectal Cancer Research Center, Department of Biochemistry, Shiraz University of Medical Sciences, Shiraz, Iran.

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April 2020

Two Simple Methods for Optimizing the Production of "Difficult-to-Express" GnRH-DFF40 Chimeric Protein.

Adv Pharm Bull 2019 Aug 1;9(3):423-431. Epub 2019 Aug 1.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran.

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August 2019

The protective effect of Stevia rebaudiana Bertoni on serum hormone levels, key steroidogenesis enzymes, and testicular damage in testes of diabetic rats.

Acta Histochem 2019 Oct 13;121(7):833-840. Epub 2019 Aug 13.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

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October 2019

Betulin and its derivatives as novel compounds with different pharmacological effects.

Biotechnol Adv 2020 Jan - Feb;38:107409. Epub 2019 Jun 18.

Department of Human Anatomy and Cell Science, Rady College of Medicine, Max Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada; Biology of Breathing Theme, Children Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, Canada; Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran; Research Institute of Oncology and Hematology, CancerCare Manitoba, University of Manitoba, Winnipeg, Canada. Electronic address:

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February 2020

BDNF Val66Met genetic variation and its plasma level in patients with morbid obesity: A case-control study.

Gene 2019 Jul 17;705:51-54. Epub 2019 Apr 17.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

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July 2019

Altered miR-21, miRNA-148a Expression in Relation to KRAS Mutation Status as Indicator of Adenoma-Carcinoma Transitional Pattern in Colorectal Adenoma and Carcinoma Lesions.

Biochem Genet 2019 Dec 17;57(6):767-780. Epub 2019 Apr 17.

Colorectal Cancer Research Center and Department of Biochemistry, Shiraz University of Medical Sciences, P.O Box 1167, Shiraz, Iran.

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December 2019

Autophagy and cancer research in Iran.

Autophagy 2019 11 23;15(11):2039-2042. Epub 2019 Apr 23.

Autophagy Research Center, Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences , Shiraz , Iran.

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November 2019

Derivative of Stevioside; CPUK02; Restores ESR1 Gene Methylation in MDA-MB 231

Asian Pac J Cancer Prev 2018 Aug 24;19(8):2117-2123. Epub 2018 Aug 24.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Email:

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August 2018

A Comparison Between Cell, Protein and Peptide-Based Approaches for Selection of Nanobodies Against CD44 from a Synthetic Library.

Protein Pept Lett 2018 ;25(6):580-588

Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.

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July 2019

O6-Methyguanine-DNA Methyl Transferase (MGMT) Promoter Methylation in Serum DNA of Iranian Patients with Colorectal Cancer

Asian Pac J Cancer Prev 2018 May 26;19(5):1223-1227. Epub 2018 May 26.

Gastroenterohepatology Research Center, Nemazi Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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May 2018

IFN-γ and IL-2 Responses to Recombinant AlaDH against ESAT-6/CFP-10 Fusion Antigens in the Diagnosis of Latent versus Active Tuberculosis Infection.

Iran J Med Sci 2017 May;42(3):275-283

Recombinant Protein Laboratory, Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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May 2017

Novel biotechnology approaches in colorectal cancer diagnosis and therapy.

Biotechnol Lett 2017 Jun 25;39(6):785-803. Epub 2017 Feb 25.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, P.O Box 1167, Shiraz, Iran.

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June 2017

Induction of Epigenetic Alteration by CPUK02, An Ent- kaurenoid Derivative of Stevioside.

Avicenna J Med Biotechnol 2017 Jan-Mar;9(1):13-18

Drug Research Institute, China Pharmaceutical University, Jiangsu, China.

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January 2017

Epigenetic biomarkers in colorectal cancer: premises and prospects.

Biomarkers 2018 Mar 10;23(2):105-114. Epub 2016 Nov 10.

b Gasteroenterohepatology Research Center , Nemazee Hospital, School of Medicine, Shiraz University of Medical Sciences , Shiraz , Iran.

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March 2018

Interconnection of Estrogen/Testosterone Metabolism and Mevalonate Pathway in Breast and Prostate Cancers.

Curr Mol Pharmacol 2017 ;10(2):86-114

Department of Biotechnology, School of Advanced Medical Science and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran.

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July 2017

Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in Iranian Patients.

Asian Pac J Cancer Prev 2015 ;16(18):8247-52

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran E-mail :

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October 2016

DNMT3b -149C/T promoter variants and methylation of colorectal cancer-associated genes.

Cancer Biomark 2015 ;15(3):227-33

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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May 2016

Optimization of RNA extraction from rat pancreatic tissue.

Iran J Med Sci 2014 May;39(3):282-8

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; ; Gasteroenterohepatology Research Center, Nemazee Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; ; Faculty for Advanced Biomedical Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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May 2014

An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors.

PLoS One 2014 27;9(1):e82185. Epub 2014 Jan 27.

Department of Pathology, Medicine and Cancer Center, Howard University, College of Medicine, Washington, DC, United States of America.

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November 2014

Epigenetic and genetic analysis of WNT signaling pathway in sporadic colorectal cancer patients from Iran.

Mol Biol Rep 2012 May 30;39(5):6171-8. Epub 2011 Dec 30.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Zand Street, Shiraz, Iran.

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May 2012

Regulation of carcinoembryonic antigen release from colorectal cancer cells.

Mol Biol Rep 2012 Apr 2;39(4):3695-704. Epub 2011 Jul 2.

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Zand Street, Shiraz, Fars, Iran.

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April 2012

High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.

Pathol Oncol Res 2011 Dec 1;17(4):819-25. Epub 2011 Apr 1.

Department of Biochemistry, Shiraz University of Medical Sciences, School of Medicine, Zand Street, Shiraz, Fars, Iran.

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December 2011

Distinct high-profile methylated genes in colorectal cancer.

PLoS One 2009 Sep 11;4(9):e7012. Epub 2009 Sep 11.

Department of Internal Medicine and Gastroenterology Research Center, Shiraz, Iran University of Medical Sciences, Tehran, Iran.

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September 2009

Easy detection of 5,10-methylenetetrahydrofolate reductase 1298A/C genotype by mutagenically separated PCR assay.

Clin Chem Lab Med 2008 ;46(7):987-9

Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

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October 2008