Polly Bingley

Polly Bingley

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Polly Bingley

Polly Bingley

Publications by authors named "Polly Bingley"

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Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Diabetologia 2016 12 3;59(12):2722-2726. Epub 2016 Sep 3.

Diabetes and Metabolism, School of Clinical Sciences, Southmead Hospital, Level 2 Learning and Research Building, Bristol, BS10 5NB, UK.

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http://dx.doi.org/10.1007/s00125-016-4087-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518060PMC
December 2016

The implications of autoantibodies to a single islet antigen in relatives with normal glucose tolerance: development of other autoantibodies and progression to type 1 diabetes.

Diabetologia 2016 Mar 16;59(3):542-9. Epub 2015 Dec 16.

Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

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http://dx.doi.org/10.1007/s00125-015-3830-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742489PMC
March 2016

Use of Dried Capillary Blood Sampling for Islet Autoantibody Screening in Relatives: A Feasibility Study.

Diabetes Technol Ther 2015 Dec 16;17(12):867-71. Epub 2015 Sep 16.

4 Division of Informatics and Biostatistics, University of South Florida , Tampa, Florida.

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http://www.liebertpub.com/doi/10.1089/dia.2015.0133
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http://dx.doi.org/10.1089/dia.2015.0133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677115PMC
December 2015

Attenuated humoral responses in HLA-A*24-positive individuals at risk of type 1 diabetes.

Diabetologia 2015 Oct 30;58(10):2284-7. Epub 2015 Jul 30.

Diabetes and Metabolism, School of Clinical Sciences, University of Bristol, Level 2 Learning and Research Building, Southmead Hospital, Bristol, BS10 5NB, UK.

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http://dx.doi.org/10.1007/s00125-015-3702-9DOI Listing
October 2015

Reactivity to N-Terminally Truncated GAD65(96-585) Identifies GAD Autoantibodies That Are More Closely Associated With Diabetes Progression in Relatives of Patients With Type 1 Diabetes.

Diabetes 2015 Sep 22;64(9):3247-52. Epub 2015 May 22.

Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Klinikum rechts der Isar, Technische Universität München, Neuherberg, Germany.

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http://dx.doi.org/10.2337/db14-1694DOI Listing
September 2015

Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial.

JAMA 2015 Apr;313(15):1541-9

Forschergruppe Diabetes e.V., Neuherberg, Germany4Institute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1001/jama.2015.2928DOI Listing
April 2015

Risk of pediatric celiac disease according to HLA haplotype and country.

N Engl J Med 2014 Jul;371(1):42-9

From the Digestive Health Institute, Children's Hospital Colorado (E.L.), and the Barbara Davis Center (E.L., M.J.R., G.S.E.), University of Colorado Denver, Aurora; the Pediatrics Epidemiology Center, University of South Florida, Tampa (H.-S.L.); the Diabetes and Celiac Disease Unit, Department of Clinical Sciences, Lund University, Malmo, Sweden (C.A.A., D.A.); Pacific Northwest Diabetes Research Institute, Seattle (W.A.H.); Dr. von Hauner Children's Hospital, Ludwig Maximilian University, Munich (S.K.), the Center for Regenerative Therapies Dresden, Technische Universitaet Dresden, Dresden (E.B.), and Forschergruppe Diabetes, Helmholz Zentrum München, Neuherberg (E.B.) - all in Germany; the School of Clinical Sciences, University of Bristol, Bristol, United Kingdom (P.J.B.); and the Department of Pediatrics, University of Turku, Turku University Hospital, Turku, Finland (V.S.).

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http://dx.doi.org/10.1056/NEJMoa1313977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163840PMC
July 2014

Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings.

Diabetes 2014 Mar 7;63(3):1041-7. Epub 2013 Nov 7.

Diabetes and Metabolism, School of Clinical Sciences, University of Bristol, Bristol, U.K.

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http://dx.doi.org/10.2337/db13-0994DOI Listing
March 2014

Islet autoantibody testing: an end to the trials and tribulations?

Diabetes 2013 Dec;62(12):4009-11

School of Clinical Sciences, University of Bristol, Bristol, U.K.

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http://dx.doi.org/10.2337/db13-1445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837043PMC
December 2013

Rising incidence of type 1 diabetes is associated with altered immunophenotype at diagnosis.

Diabetes 2012 Mar 7;61(3):683-6. Epub 2012 Feb 7.

School of Clinical Sciences, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.2337/db11-0962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282823PMC
March 2012

Diabetes Antibody Standardization Program: First evaluation of assays for autoantibodies to IA-2β.

Diabetes Care 2011 Nov 16;34(11):2410-2. Epub 2011 Sep 16.

Department of Medical Biochemistry and Molecular Biology, Research Group of Predictive Diagnostics,University ofGreifswald, Karlsburg, Germany.

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http://care.diabetesjournals.org/cgi/doi/10.2337/dc11-1161
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http://dx.doi.org/10.2337/dc11-1161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198291PMC
November 2011

Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct.

Diabetes 2011 Oct 10;60(10):2635-44. Epub 2011 Aug 10.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetesand Inflammation Laboratory, Cambridge Institute for Medical Research, Departmentof Medical Genetics, University of Cambridge, Cambridge, U.K.

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http://dx.doi.org/10.2337/db11-0131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178284PMC
October 2011

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

PLoS Genet 2011 Aug 4;7(8):e1002216. Epub 2011 Aug 4.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150451PMC
August 2011

Anti-BSA antibodies are a major cause of non-specific binding in insulin autoantibody radiobinding assays.

J Immunol Methods 2010 Oct 9;362(1-2):199-203. Epub 2010 Sep 9.

School of Clinical Sciences, University of Bristol, Bristol, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00221759100026
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http://dx.doi.org/10.1016/j.jim.2010.09.009DOI Listing
October 2010

Clinical applications of diabetes antibody testing.

Authors:
Polly J Bingley

J Clin Endocrinol Metab 2010 Jan 29;95(1):25-33. Epub 2009 Oct 29.

Department of Clinical Science at North Bristol, Medical School Unit, Southmead Hospital, Bristol BS10 5NB, United Kingdom.

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http://jcem.publicaciones.saludcastillayleon.es/content/95/1
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http://www.kalbemed.com/Portals/6/komelibnew/2015/03/Clinica
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http://press.endocrine.org/doi/abs/10.1210/jc.2009-1365
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http://dx.doi.org/10.1210/jc.2009-1365DOI Listing
January 2010

Insulin resistance and progression to type 1 diabetes in the European Nicotinamide Diabetes Intervention Trial (ENDIT).

Diabetes Care 2008 Jan 24;31(1):146-50. Epub 2007 Oct 24.

Clinical Science at North Bristol, University of Bristol, UK.

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http://dx.doi.org/10.2337/dc07-0103DOI Listing
January 2008

Cerebellar ataxia, peripheral neuropathy, "gluten sensitivity" and anti-neuronal autoantibodies.

Clin Lab 2006 ;52(11-12):589-92

Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Bristol, UK.

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January 2007

Islet autoimmunity in children with Down's syndrome.

Diabetes 2006 Nov;55(11):3185-8

Medical School Unit, Southmead Hospital, Bristol BS10 5NB, UK.

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http://dx.doi.org/10.2337/db06-0856DOI Listing
November 2006

Is puberty an accelerator of type 1 diabetes in IL6-174CC females?

Diabetes 2005 Apr;54(4):1245-8

Department of Diabetes and Metabolism, Division of Medicine, University of Bristol, UK.

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http://dx.doi.org/10.2337/diabetes.54.4.1245DOI Listing
April 2005

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes.

Lancet 2004 Nov 6-12;364(9446):1699-700

Diabetes and Metabolism, Division of Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1016/S0140-6736(04)17357-1DOI Listing
November 2004

Validation of autoantibody assays in type 1 diabetes: workshop programme.

Autoimmunity 2004 Jun;37(4):257-60

Department of Clinical Science at North Bristol, University of Bristol, UK.

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http://dx.doi.org/10.1080/08916930410001710677DOI Listing
June 2004

Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics.

Diabetes 2004 Feb;53(2):384-92

Diabetes Research Institute and 3rd Medical Department, Hospital München-Schwabing, Munich, Germany.

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http://dx.doi.org/10.2337/diabetes.53.2.384DOI Listing
February 2004

Association of intercellular adhesion molecule-1 gene with type 1 diabetes.

Lancet 2003 Nov;362(9397):1723-4

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, CB2 2XY, Cambridge, UK.

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http://dx.doi.org/10.1016/S0140-6736(03)14847-7DOI Listing
November 2003

Diabetes Antibody Standardization Program: first assay proficiency evaluation.

Diabetes 2003 May;52(5):1128-36

Division of Medicine, Medical School Unit, University of Bristol, Southmead Hospital, Bristol BS10 5NB, U.K.

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http://dx.doi.org/10.2337/diabetes.52.5.1128DOI Listing
May 2003

Identifying hepatic nuclear factor 1alpha mutations in children and young adults with a clinical diagnosis of type 1 diabetes.

Diabetes Care 2003 Feb;26(2):333-7

Department of Diabetes and Metabolism, Division of Medicine, University of Bristol, UK.

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http://dx.doi.org/10.2337/diacare.26.2.333DOI Listing
February 2003

Predicting type 1 diabetes using autoantibodies: the latest results from the diabetes autoantibody standardization program.

Diabetes Technol Ther 2002 ;4(3):397-400

Centers for Disease Control and Prevention, Atlanta, GA 30341-3724, USA.

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http://dx.doi.org/10.1089/152091502760098537DOI Listing
January 2003

High familial risk and genetic susceptibility in early onset childhood diabetes.

Diabetes 2002 Jan;51(1):210-4

Department of Diabetes and Metabolism, Division of Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.2337/diabetes.51.1.210DOI Listing
January 2002