Pixu Liu

Pixu Liu

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Pixu Liu

Pixu Liu

Publications by authors named "Pixu Liu"

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Targeting the EphB4 receptor tyrosine kinase sensitizes HER2-positive breast cancer cells to Lapatinib.

Cancer Lett 2020 Apr 29;475:53-64. Epub 2020 Jan 29.

Cancer Institute, Department of Oncology, Department of Thoracic Surgery, The Second Hospital of Dalian Medical University, Dalian Key Laboratory of Molecular Targeted Cancer Therapy, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2020.01.032DOI Listing
April 2020

Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer.

Redox Biol 2019 06 20;24:101225. Epub 2019 May 20.

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, Liaoning, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317193021
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http://dx.doi.org/10.1016/j.redox.2019.101225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536746PMC
June 2019

Author Correction: Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling.

Cell Death Dis 2019 Jun 24;10(7):501. Epub 2019 Jun 24.

Cancer Institute, Department of Acute Abdomen Surgery, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, 116044, China.

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http://dx.doi.org/10.1038/s41419-019-1692-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591411PMC
June 2019

Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation.

Oncol Rep 2019 May 14;41(5):2667-2678. Epub 2019 Mar 14.

Institute of Cancer Stem Cell, Dalian Medical University, Dalian, Liaoning 116044, P.R. China.

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http://dx.doi.org/10.3892/or.2019.7067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448098PMC
May 2019

MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer.

EBioMedicine 2019 May 18;43:225-237. Epub 2019 Mar 18.

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.03.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557734PMC
May 2019

Inhibition of BTF3 sensitizes luminal breast cancer cells to PI3Kα inhibition through the transcriptional regulation of ERα.

Cancer Lett 2019 01 10;440-441:54-63. Epub 2018 Oct 10.

Cancer Institute, The Second Hospital of Dalian Medical University, Dalian Key Laboratory of Molecular Targeted Cancer Therapy, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, Liaoning, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.09.030DOI Listing
January 2019

Patient-derived xenograft mouse models: A high fidelity tool for individualized medicine.

Oncol Lett 2019 Jan 16;17(1):3-10. Epub 2018 Oct 16.

Department of Acute Abdomen Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning 116023, P.R. China.

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http://dx.doi.org/10.3892/ol.2018.9583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313209PMC
January 2019

Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.

Cell Physiol Biochem 2018 5;47(6):2261-2277. Epub 2018 Jul 5.

Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.1159/000491537DOI Listing
August 2018

Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling.

Cell Death Dis 2018 07 24;9(8):809. Epub 2018 Jul 24.

Cancer Institute, Department of Acute Abdomen Surgery, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, 116044, China.

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http://www.nature.com/articles/s41419-018-0849-6
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http://dx.doi.org/10.1038/s41419-018-0849-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057974PMC
July 2018

Clinical significance of detecting CSF-derived tumor cells in breast cancer patients with leptomeningeal metastasis.

Oncotarget 2018 Jan 21;9(2):2705-2714. Epub 2017 Dec 21.

The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.18632/oncotarget.23597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788671PMC
January 2018

Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo.

Biomed Pharmacother 2017 Nov 18;95:18-24. Epub 2017 Aug 18.

Department of Biotechnology, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2017.08.045DOI Listing
November 2017

Reviewing the Management of Obstructive Left Colon Cancer: Assessing the Feasibility of the One-stage Resection and Anastomosis After Intraoperative Colonic Irrigation.

Clin Colorectal Cancer 2017 06 18;16(2):e89-e103. Epub 2017 Jan 18.

Department of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2016.12.001DOI Listing
June 2017

Combined inhibition of PI3K and PARP is effective in the treatment of ovarian cancer cells with wild-type PIK3CA genes.

Gynecol Oncol 2016 09 15;142(3):548-56. Epub 2016 Jul 15.

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.07.092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551048PMC
September 2016

Splenic abscess owing to cancer at the splenic flexure: A case report and comprehensive review.

Medicine (Baltimore) 2016 Sep;95(38):e4941

aDepartment of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, P.R. China bThe First Affiliated Hospital Collaborative Innovation Center of Oncology-Institute of Cancer Stem Cell, Dalian Medical University, Dalian City, Liaoning Province, P.R. China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044920PMC
http://dx.doi.org/10.1097/MD.0000000000004941DOI Listing
September 2016

Saikosaponin-a Attenuates Oxidized LDL Uptake and Prompts Cholesterol Efflux in THP-1 Cells.

J Cardiovasc Pharmacol 2016 Jun;67(6):510-8

*Department of Cardiology, Institute of Heart and Vessel Diseases of Dalian Medical University, The Second Affiliated Hospital of Dalian Medical University, Dalian, China; †Department of Neurology, Xinhua Hospital Affiliated of Dalian University, Dalian, China; ‡Department of Cardiology, The First Affiliated Hospital of Nanhua University, Hengyang, China; and §Department of Cancer Center, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.

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http://dx.doi.org/10.1097/FJC.0000000000000373DOI Listing
June 2016

Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer.

Oncotarget 2016 Mar;7(11):13153-66

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.

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http://dx.doi.org/10.18632/oncotarget.7549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914348PMC
March 2016

Neuroleukin/Autocrine Motility Factor Receptor Pathway Promotes Proliferation of Articular Chondrocytes through Activation of AKT and Smad2/3.

Sci Rep 2015 Oct 13;5:15101. Epub 2015 Oct 13.

Department of Orthopaedics, First Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.

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http://dx.doi.org/10.1038/srep15101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602231PMC
October 2015

Sialyltransferase7A, a Klf4-responsive gene, promotes cardiomyocyte apoptosis during myocardial infarction.

Basic Res Cardiol 2015 May 10;110(3):28. Epub 2015 Apr 10.

Department of Physiology, Dalian Medical University, Dalian, People's Republic of China,

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http://dx.doi.org/10.1007/s00395-015-0484-7DOI Listing
May 2015

Chemopreventive effects of aspirin at a glance.

Biochim Biophys Acta 2015 Apr 2;1855(2):254-63. Epub 2015 Apr 2.

Cancer Institute, Second Affiliated Hospital, Dalian Medical University, Dalian, Liaoning, China; Institute of Cancer Stem Cell, Dalian Medical University, Dalian, Liaoning, China; Department of Cancer Biology, Dana-Farber Cancer Institute Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2015.03.007DOI Listing
April 2015

Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling.

Chem Biol Interact 2015 Feb 8;228:100-7. Epub 2014 Dec 8.

Department of Pathology, Dalian Medical University, Dalian 116044, PR China; The Key Laboratory of Tumor Stem Cell Research of Liaoning Province, Dalian Medical University, Dalian 116044, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.12.002DOI Listing
February 2015

A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 Is highly responsive to mTOR inhibition.

Cancer Res 2014 Jan 9;74(1):15-23. Epub 2013 Dec 9.

Authors' Affiliations: Department of Cancer Biology; Division of Women's Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of Biological Chemistry and Molecular Pharmacology and Systems Biology; Rodent Histopathology Core, DF/HCC, Harvard Medical School; Department of Surgery, Brigham and Women's Hospital; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston; Novartis Institutes for Biomedical Research, Cambridge, Massacheusetts; Department of System Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Novartis Institutes for Biomedical Research, Oncology Disease Area, Novartis Pharma AG, Basel, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982380PMC
January 2014

Targeting the phosphoinositide 3-kinase pathway in cancer.

Nat Rev Drug Discov 2009 Aug;8(8):627-44

Department of Cancer Biology, Dana-Farber Cancer Institute, Pathology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/nrd2926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142564PMC
August 2009

Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.

Nature 2008 Aug 25;454(7205):776-9. Epub 2008 Jun 25.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature07091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750091PMC
August 2008

An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2.

J Biol Chem 2005 Dec 4;280(48):39677-80. Epub 2005 Oct 4.

Pulmonary Division, Department of Pediatrics, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.C500287200DOI Listing
December 2005