Pippa Thomson

Pippa Thomson

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Pippa Thomson

Pippa Thomson

Publications by authors named "Pippa Thomson"

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Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.

PLoS One 2018 20;13(12):e0209160. Epub 2018 Dec 20.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209160PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301766PMC
May 2019

Rediscovering the value of families for psychiatric genetics research.

Mol Psychiatry 2019 04 28;24(4):523-535. Epub 2018 Jun 28.

South Texas Diabetes and Obesity Institute, Department of Human Genetics, School of Medicine, University of Texas of the Rio Grande Valley, Brownsville, TX, USA.

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http://dx.doi.org/10.1038/s41380-018-0073-xDOI Listing
April 2019

Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

Transl Psychiatry 2019 02 4;9(1):14. Epub 2019 Feb 4.

Medical Genetics Section, University of Edinburgh, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41398-018-0360-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361928PMC
February 2019

A validation of the diathesis-stress model for depression in Generation Scotland.

Transl Psychiatry 2019 01 18;9(1):25. Epub 2019 Jan 18.

Medical Genetics Section, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41398-018-0356-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338746PMC
January 2019

Altered DNA methylation associated with a translocation linked to major mental illness.

NPJ Schizophr 2018 Mar 19;4(1). Epub 2018 Mar 19.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1038/s41537-018-0047-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859082PMC
March 2018

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort.

Am J Med Genet B Neuropsychiatr Genet 2017 Apr 2;174(3):227-234. Epub 2016 Aug 2.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.32478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363226PMC
April 2017

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder.

Biol Psychiatry 2017 02 2;81(4):336-346. Epub 2016 May 2.

Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom; Generation Scotland, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2016.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262437PMC
February 2017

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.

Biol Psychiatry 2017 02 24;81(4):325-335. Epub 2016 May 24.

Institute of Psychiatry, Psychology, and Neuroscience, King׳s College London, London. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2016.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5262436PMC
February 2017

Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression.

EBioMedicine 2016 Dec 4;14:161-167. Epub 2016 Nov 4.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.ebiom.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161419PMC
December 2016

Expression of DISC1-interactome members correlates with cognitive phenotypes related to schizophrenia.

PLoS One 2014 18;9(6):e99892. Epub 2014 Jun 18.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, Medical Genetics Section, Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099892PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062455PMC
July 2015

White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder.

Psychiatry Res 2013 Apr 4;206(2-3):223-31. Epub 2012 Dec 4.

Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1016/j.psychres.2012.11.002DOI Listing
April 2013

DISC1 genetics, biology and psychiatric illness.

Front Biol (Beijing) 2013 Feb;8(1):1-31

The Centre for Molecular Medicine at the Medical Research Council Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1007/s11515-012-1254-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580875PMC
February 2013

The DISC1 promoter: characterization and regulation by FOXP2.

Hum Mol Genet 2012 Jul 20;21(13):2862-72. Epub 2012 Mar 20.

Medical Genetics Section, Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1093/hmg/dds111DOI Listing
July 2012

Developmental expression of orphan G protein-coupled receptor 50 in the mouse brain.

ACS Chem Neurosci 2012 Jun 15;3(6):459-72. Epub 2012 Apr 15.

Medical Genetics Section, University of Edinburgh, Institute of Genetics and Molecular Medicine, Molecular Medicine Centre, Crewe Road, Edinburgh EH2 4XU, United Kingdom.

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http://pubs.acs.org/doi/10.1021/cn300008p
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http://dx.doi.org/10.1021/cn300008pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382458PMC
June 2012

Alzheimer's disease risk factor complement receptor 1 is associated with depression.

Neurosci Lett 2012 Feb 8;510(1):6-9. Epub 2012 Jan 8.

Medical Genetics, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.neulet.2011.12.059DOI Listing
February 2012

PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1.

J Neurosci 2011 Jun;31(24):9043-54

Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.

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http://dx.doi.org/10.1523/JNEUROSCI.5410-10.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610090PMC
June 2011

DISC1 in schizophrenia: genetic mouse models and human genomic imaging.

Schizophr Bull 2011 Jan 13;37(1):14-20. Epub 2010 Dec 13.

Department of Psychiatry, The Royal Edinburgh Hospital, Morningside Terrace, Edinburgh EH10 5HF, UK.

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https://academic.oup.com/schizophreniabulletin/article-looku
Publisher Site
http://dx.doi.org/10.1093/schbul/sbq135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004186PMC
January 2011

DISC1 and Huntington's disease--overlapping pathways of vulnerability to neurological disorder?

PLoS One 2011 Jan 26;6(1):e16263. Epub 2011 Jan 26.

Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016263PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027647PMC
January 2011

Association analysis of Neuregulin 1 candidate regions in schizophrenia and bipolar disorder.

Neurosci Lett 2010 Jun 7;478(1):9-13. Epub 2010 May 7.

Medical Genetics Section, Centre for Molecular Medicine and Institute of Genetics and Molecular Medicine, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1016/j.neulet.2010.04.056DOI Listing
June 2010

Association of GPR50, an X-linked orphan G protein-coupled receptor, and affective disorder in an independent sample of the Scottish population.

Neurosci Lett 2010 May 3;475(3):169-73. Epub 2010 Apr 3.

Division of Psychiatry, University of Edinburgh, Kennedy Tower, Royal Edinburgh Hospital, EH10 5HF, UK.

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http://dx.doi.org/10.1016/j.neulet.2010.03.072DOI Listing
May 2010

GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth.

Mol Cell Neurosci 2009 Dec 21;42(4):363-71. Epub 2009 Aug 21.

Medical Genetics Section, University of Edinburgh, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh EH42XU, UK.

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http://dx.doi.org/10.1016/j.mcn.2009.08.007DOI Listing
December 2009

Are some genetic risk factors common to schizophrenia, bipolar disorder and depression? Evidence from DISC1, GRIK4 and NRG1.

Neurotox Res 2007 Jan;11(1):73-83

Division of Psychiatry, The University of Edinburgh, Royal Edinburgh Hospital, Edinburgh EH10 5HF, UK.

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http://dx.doi.org/10.1007/bf03033484DOI Listing
January 2007

A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms.

Nat Neurosci 2006 Dec 29;9(12):1477-8. Epub 2006 Oct 29.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK.

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http://dx.doi.org/10.1038/nn1795DOI Listing
December 2006

Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.

Schizophr Bull 2006 Jul 12;32(3):409-16. Epub 2006 May 12.

Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland.

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http://dx.doi.org/10.1093/schbul/sbj079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632250PMC
July 2006

The genetics and biology of DISC1--an emerging role in psychosis and cognition.

Biol Psychiatry 2006 Jul;60(2):123-31

Medical Genetics Section, Molecular Medicine Centre, University of Edinburgh, Crewe Road South, Edinburgh.

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http://dx.doi.org/10.1016/j.biopsych.2006.04.008DOI Listing
July 2006

DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness.

Ann Med 2004 ;36(5):367-78

Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1080/07853890410033603DOI Listing
March 2005