Publications by authors named "Pippa A Thomson"

39Publications

Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland.

Transl Psychiatry 2019 02 4;9(1):14. Epub 2019 Feb 4.

Medical Genetics Section, University of Edinburgh, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, Edinburgh, UK.

View Article and Find Full Text PDF
February 2019

A validation of the diathesis-stress model for depression in Generation Scotland.

Transl Psychiatry 2019 01 18;9(1):25. Epub 2019 Jan 18.

Medical Genetics Section, Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

View Article and Find Full Text PDF
January 2019

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.

PLoS One 2018 20;13(12):e0209160. Epub 2018 Dec 20.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

View Article and Find Full Text PDF
May 2019

Altered DNA methylation associated with a translocation linked to major mental illness.

NPJ Schizophr 2018 Mar 19;4(1). Epub 2018 Mar 19.

Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK.

View Article and Find Full Text PDF
March 2018

Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression.

EBioMedicine 2016 Dec 4;14:161-167. Epub 2016 Nov 4.

Division of Psychiatry, University of Edinburgh, Edinburgh, UK; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.

View Article and Find Full Text PDF
December 2016

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort.

Am J Med Genet B Neuropsychiatr Genet 2017 Apr 2;174(3):227-234. Epub 2016 Aug 2.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, United Kingdom.

View Article and Find Full Text PDF
April 2017

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder.

Biol Psychiatry 2017 02 2;81(4):336-346. Epub 2016 May 2.

Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom; Generation Scotland, University of Edinburgh, Edinburgh, United Kingdom.

View Article and Find Full Text PDF
February 2017

DISC1 genetics, biology and psychiatric illness.

Front Biol (Beijing) 2013 Feb;8(1):1-31

The Centre for Molecular Medicine at the Medical Research Council Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

View Article and Find Full Text PDF
February 2013

Developmental expression of orphan G protein-coupled receptor 50 in the mouse brain.

ACS Chem Neurosci 2012 Jun 15;3(6):459-72. Epub 2012 Apr 15.

Medical Genetics Section, University of Edinburgh, Institute of Genetics and Molecular Medicine, Molecular Medicine Centre, Crewe Road, Edinburgh EH2 4XU, United Kingdom.

View Article and Find Full Text PDF
June 2012

The DISC1 promoter: characterization and regulation by FOXP2.

Hum Mol Genet 2012 Jul 20;21(13):2862-72. Epub 2012 Mar 20.

Medical Genetics Section, Molecular Medicine Centre, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK.

View Article and Find Full Text PDF
July 2012

Alzheimer's disease risk factor complement receptor 1 is associated with depression.

Neurosci Lett 2012 Feb 8;510(1):6-9. Epub 2012 Jan 8.

Medical Genetics, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh, UK.

View Article and Find Full Text PDF
February 2012

PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1.

J Neurosci 2011 Jun;31(24):9043-54

Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.

View Article and Find Full Text PDF
June 2011

DISC1 and Huntington's disease--overlapping pathways of vulnerability to neurological disorder?

PLoS One 2011 Jan 26;6(1):e16263. Epub 2011 Jan 26.

Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom.

View Article and Find Full Text PDF
January 2011

DISC1 in schizophrenia: genetic mouse models and human genomic imaging.

Schizophr Bull 2011 Jan 13;37(1):14-20. Epub 2010 Dec 13.

Department of Psychiatry, The Royal Edinburgh Hospital, Morningside Terrace, Edinburgh EH10 5HF, UK.

View Article and Find Full Text PDF
January 2011

Association analysis of Neuregulin 1 candidate regions in schizophrenia and bipolar disorder.

Neurosci Lett 2010 Jun 7;478(1):9-13. Epub 2010 May 7.

Medical Genetics Section, Centre for Molecular Medicine and Institute of Genetics and Molecular Medicine, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK.

View Article and Find Full Text PDF
June 2010

GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth.

Mol Cell Neurosci 2009 Dec 21;42(4):363-71. Epub 2009 Aug 21.

Medical Genetics Section, University of Edinburgh, Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh EH42XU, UK.

View Article and Find Full Text PDF
December 2009

A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms.

Nat Neurosci 2006 Dec 29;9(12):1477-8. Epub 2006 Oct 29.

Division of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK.

View Article and Find Full Text PDF
December 2006

DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness.

Ann Med 2004 ;36(5):367-78

Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK.

View Article and Find Full Text PDF
March 2005