Publications by authors named "Piotr Sliz"

49Publications

International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium.

NPJ Digit Med 2020 19;3:109. Epub 2020 Aug 19.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA USA.

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August 2020

Virtual Screening for Ligand Discovery at the σ Receptor.

ACS Med Chem Lett 2020 Aug 27;11(8):1555-1561. Epub 2020 Jul 27.

Harvard Medical School, Department of Biological Chemistry and Molecular Pharmacology, Boston, Massachusetts 02115, United States.

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August 2020

RiboToolkit: an integrated platform for analysis and annotation of ribosome profiling data to decode mRNA translation at codon resolution.

Nucleic Acids Res 2020 07;48(W1):W218-W229

Stem Cell Program, Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA.

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July 2020

A nanobody targeting the LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7.

Proc Natl Acad Sci U S A 2020 03 14;117(9):4653-4663. Epub 2020 Feb 14.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;

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March 2020

In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.

ChemMedChem 2018 12 8;13(23):2479-2483. Epub 2018 Nov 8.

Department of Chemistry, Duke University, 124 Science Drive, Durham, NC, 27708, USA.

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December 2018

Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28.

Cell Rep 2018 06;23(10):3091-3101

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA. Electronic address:

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June 2018

Comparative analysis of LIN28-RNA binding sites identified at single nucleotide resolution.

RNA Biol 2017 12 9;14(12):1756-1765. Epub 2017 Oct 9.

a Department of Biological Chemistry and Molecular Pharmacology , Harvard Medical School , Boston , MA.

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December 2017

MightyScreen: An Open-Source Visualization Application for Screening Data Analysis.

SLAS Discov 2018 02 22;23(2):218-223. Epub 2017 Sep 22.

1 Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.

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February 2018

LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation.

Cell Rep 2017 03;18(11):2664-2675

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA. Electronic address:

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March 2017

Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis.

Proc Natl Acad Sci U S A 2017 03 21;114(10):E1848-E1856. Epub 2017 Feb 21.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;

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March 2017

Extension of research data repository system to support direct compute access to biomedical datasets: enhancing Dataverse to support large datasets.

Ann N Y Acad Sci 2017 01 10;1387(1):95-104. Epub 2016 Nov 10.

Department of Biochemistry and Molecular Pharmacology and SBGrid Initiative, Harvard Medical School, Boston, Massachusetts, and the Dataverse Project, Harvard University, Cambridge, Massachusetts.

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January 2017

Pulmonary Vasculopathy Associated with FIGF Gene Mutation.

Am J Pathol 2017 Jan 12;187(1):25-32. Epub 2016 Nov 12.

Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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January 2017

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency.

Cell Stem Cell 2016 07 16;19(1):66-80. Epub 2016 Jun 16.

Stem Cell Transplantation Program, Division of Pediatric Hematology Oncology, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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July 2016

Pinpointing RNA-Protein Cross-Links with Site-Specific Stable Isotope-Labeled Oligonucleotides.

J Am Chem Soc 2015 Dec 3;137(49):15378-81. Epub 2015 Dec 3.

Department of Molecular Biology and Center for Computational and Integrative Biology, Howard Hughes Medical Institute, Massachusetts General Hospital , Boston, Massachusetts 02114, United States.

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December 2015

A Biogenesis Step Upstream of Microprocessor Controls miR-17∼92 Expression.

Cell 2015 Aug 6;162(4):885-99. Epub 2015 Aug 6.

Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Boston, MA 02115, USA. Electronic address:

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August 2015