Ping Yue

Ping Yue

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Ping Yue

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Optimal dilation time for combined small endoscopic sphincterotomy and balloon dilation for common bile duct stones: a multicentre, single-blinded, randomised controlled trial.

Lancet Gastroenterol Hepatol 2019 Jun 16;4(6):425-434. Epub 2019 Apr 16.

Fifth Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, China; Hepatopancreatobiliary Surgery Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, Lanzhou, China; Key Laboratory of Biological Therapy and Regenerative Medicine Transformation Gansu Province, Lanzhou, China. Electronic address:

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http://dx.doi.org/10.1016/S2468-1253(19)30075-5DOI Listing
June 2019

Treatment of Diabetic Foot Gangrene Using the STAGE Principle: A Case Series.

Int J Low Extrem Wounds 2019 Apr 10:1534734619840584. Epub 2019 Apr 10.

1 Second Affiliated Hospital of Tianjin University of TCM, Tianjin, China.

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http://dx.doi.org/10.1177/1534734619840584DOI Listing
April 2019

The Growth and N Retention of Two Annual Desert Plants Varied Under Different Nitrogen Deposition Rates.

Front Plant Sci 2019 26;10:356. Epub 2019 Mar 26.

Key Laboratory of Plant-Soil Interactions of the Ministry of Education, Beijing Key Laboratory of Farmland Soil Pollution Prevention and Remediation, College of Resources and Environmental Sciences, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fpls.2019.00356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443888PMC
March 2019

Salinity Is a Key Determinant for Soil Microbial Communities in a Desert Ecosystem.

mSystems 2019 Jan-Feb;4(1). Epub 2019 Feb 12.

State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing, China.

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http://dx.doi.org/10.1128/mSystems.00225-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372838PMC
February 2019

Double pigtail stents healed acute pancreatitis resulting from afferent loop obstruction.

Turk J Gastroenterol 2018 11;29(6):705-707

Hepatopancreatobiliary Surgery Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, Lanzhou, China; The Fifth General Surgery Department, The First Hospital of Lanzhou University, Lanzhou, China.

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http://www.turkjgastroenterol.org/eng/makale/5413/310/Full-T
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http://dx.doi.org/10.5152/tjg.2018.17685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284688PMC
November 2018

Cancer cell specific fluorescent methionine protected gold nanoclusters for in-vitro cell imaging studies.

Talanta 2018 Oct 29;188:259-265. Epub 2018 May 29.

Department of Chemistry and Centre for Atomic Engineering of Advanced Materials, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei, Anhui 230601, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2018.05.079DOI Listing
October 2018

Emergent Endoscopic Retrograde Cholangiopancreatography with Placement of Biliary Double Stents to Salvage Endoscopic Retrograde Cholangiopancreatography-Induced Stapfer's Type II Perforation.

Chin Med J (Engl) 2018 10;131(19):2346-2348

The Fifth Department of General Surgery, The First Hospital of Lanzhou University; Key Laboratory of Biological Therapy and Regenerative Medicine Transformation Gansu Province, Lanzhou, Gansu 730000, China.

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http://dx.doi.org/10.4103/0366-6999.241798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166458PMC
October 2018

[Analysis of TCOF1 mutation in a Chinese patient with Treacher-Collins syndrome].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2018 Oct;35(5):683-685

Central Laboratory, Children's Hospital of Jiangxi Province, Nanchang, Jiangxi 330006, China.

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2018.05.014DOI Listing
October 2018

Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-κB decoy oligodeoxynucleotides.

Drug Des Devel Ther 2017 13;11:2997-3007. Epub 2017 Oct 13.

School of Clinical Laboratory Science, Guizhou Medical University, Guiyang, Guizhou.

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http://dx.doi.org/10.2147/DDDT.S145421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648311PMC
July 2018

In Situ Lysosomal Cysteine-Specific Targeting and Imaging during Dexamethasone-Induced Apoptosis.

Anal Chem 2018 06 18;90(11):7018-7024. Epub 2018 May 18.

Department of Chemistry , Portland State University , Portland , Oregon 97201 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b01406DOI Listing
June 2018

A mitochondria-targeted ratiometric two-photon fluorescent probe for detecting intracellular cysteine and homocysteine.

Talanta 2018 Feb 30;178:24-30. Epub 2017 Aug 30.

School of Chemistry and Chemical Engineering & Center for Atomic Engineering of Advanced Materials & AnHui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei 230601, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.talanta.2017.08.085DOI Listing
February 2018

Unusual self-healing of a traumatic pancreatic fistula that persisted for 16 months.

Turk J Gastroenterol 2018 01;29(1):138-139

Department of Hepatopancreatobiliary Surgery, Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, Gansu, China; Department of The Fifth General Surgery, The First Hospital of Lanzhou University, Gansu, China.

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http://dx.doi.org/10.5152/tjg.2018.17424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322626PMC
January 2018

Impacts of water and nitrogen addition on nitrogen recovery in Haloxylon ammodendron dominated desert ecosystems.

Sci Total Environ 2017 Dec 9;601-602:1280-1288. Epub 2017 Jun 9.

Key Laboratory of Plant-Soil Interactions of MOE, Beijing Key Laboratory of Farmland Soil Pollution Prevention and Remediation, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China. Electronic address:

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http://dx.doi.org/10.1016/j.scitotenv.2017.05.202DOI Listing
December 2017

Identification and Comparison of Differentiation-Related Proteins in Hepatocellular Carcinoma Tissues by Proteomics.

Technol Cancer Res Treat 2017 12 25;16(6):1092-1101. Epub 2017 Sep 25.

1 Special Minimally Invasive Surgery, The First Clinical Medical College of Lanzhou University, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.

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http://dx.doi.org/10.1177/1533034617732426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762076PMC
December 2017

TPZ, a bright centrosymmetric two-photon scaffold for bioimaging.

Chem Commun (Camb) 2017 Oct;53(79):10938-10941

Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

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http://dx.doi.org/10.1039/c7cc06031aDOI Listing
October 2017

Inhibition of p70S6K does not mimic the enhancement of Akt phosphorylation by rapamycin.

Heliyon 2017 Aug 8;3(8):e00378. Epub 2017 Aug 8.

Departments of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24058440173067
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http://dx.doi.org/10.1016/j.heliyon.2017.e00378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552102PMC
August 2017

Re: Forceps-related endoscopic transpapillary biliary biopsy programmes, reply: endoscopic biopsy techniques for proximal biliary strictures.

Turk J Gastroenterol 2017 05 15;28(3):225-226. Epub 2017 Mar 15.

Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, China; Hepatopancreatobiliary Surgery Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, Lanzhou, China.

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http://dx.doi.org/10.5152/tjg.2017.0204012DOI Listing
May 2017

DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion.

Cell Commun Signal 2017 05 8;15(1):18. Epub 2017 May 8.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, 1365-C Clifton Road, Clinical Building C3088, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1186/s12964-017-0174-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422905PMC
May 2017

Accurate biopsy of bile duct without destroying duodenal papilla.

Turk J Gastroenterol 2017 Jan 23;28(1):67-68. Epub 2016 Dec 23.

Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, China; 2Hepatopancreatobiliary Surgery Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, Lanzhou, China.

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http://dx.doi.org/10.5152/tjg.2016.0411DOI Listing
January 2017

Narrow band imaging helps identify the ectopic opening of the common bile duct during endoscopic retrograde cholangiopancreatography.

Turk J Gastroenterol 2017 01 23;28(1):69-70. Epub 2016 Dec 23.

Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, China; Hepatopancreatobiliary Surgery Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, Lanzhou, China.

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http://dx.doi.org/10.5152/tjg.2016.0582DOI Listing
January 2017

Di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis through activating the Ras/Akt/TRHr pathway and inducing hepatic enzymes.

Sci Rep 2017 01 9;7:40153. Epub 2017 Jan 9.

Key Lab of Birth Defects and Reproductive Health of National Health and Family Planning Commission, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing 400020, P.R. China.

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http://dx.doi.org/10.1038/srep40153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220292PMC
January 2017

Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.

Cancer Lett 2016 10 19;380(2):494-504. Epub 2016 Jul 19.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. Electronic address:

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http://search.proquest.com/openview/96fc37bbd6ea5af450a03f13
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http://dx.doi.org/10.1016/j.canlet.2016.07.021DOI Listing
October 2016

Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition.

J Biol Chem 2016 Oct 30;291(41):21694-21702. Epub 2016 Aug 30.

the Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322

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http://dx.doi.org/10.1074/jbc.M116.738302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076838PMC
October 2016

A five-year study of the impact of nitrogen addition on methane uptake in alpine grassland.

Sci Rep 2016 08 30;6:32064. Epub 2016 Aug 30.

College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.1038/srep32064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004186PMC
August 2016

[Effect of Warm-needle-moxibustion on Behavior Reactions and TNF-α and MMP-3 Contents in Knee Cartilage of Rabbits with Knee Osteoarthritis].

Zhen Ci Yan Jiu 2016 Jun;41(3):235-9

School of Acu-moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, Chin.

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June 2016

The immunosuppression role of alpha-fetoprotein in human hepatocellular carcinoma.

Discov Med 2016 06;21(118):489-94

Storr Liver Centre, the Westmead Institute for Medical Research, Department of Medicine, The University of Sydney at Westmead Hospital, Westmead, NSW 2145, Australia.

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June 2016

Paradoxical activation of MEK/ERK signaling induced by B-Raf inhibition enhances DR5 expression and DR5 activation-induced apoptosis in Ras-mutant cancer cells.

Sci Rep 2016 05 25;6:26803. Epub 2016 May 25.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1038/srep26803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879700PMC
May 2016

Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling.

Oncotarget 2015 Dec;6(38):41324-38

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.

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http://www.oncotarget.com/fulltext/5847
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http://dx.doi.org/10.18632/oncotarget.5847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747408PMC
December 2015

Role of Helicobacter pylori in gastric cancer: advances and controversies.

Discov Med 2015 Nov;20(111):285-93

Storr Liver Centre, Westmead Millennium Institute for Medical Research, Department of Medicine, The University of Sydney at Westmead Hospital, NSW 2145, Australia.

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November 2015

The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition.

Oncotarget 2015 Oct;6(33):34669-79

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.18632/oncotarget.5785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741481PMC
October 2015

Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.

Cancer Lett 2015 Aug 29;364(1):70-8. Epub 2015 Apr 29.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835150030
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http://dx.doi.org/10.1016/j.canlet.2015.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450809PMC
August 2015

mTOR Complex 2 Stabilizes Mcl-1 Protein by Suppressing Its Glycogen Synthase Kinase 3-Dependent and SCF-FBXW7-Mediated Degradation.

Mol Cell Biol 2015 Jul 27;35(13):2344-55. Epub 2015 Apr 27.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, USA

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http://dx.doi.org/10.1128/MCB.01525-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456440PMC
July 2015

Response of alpine grassland to elevated nitrogen deposition and water supply in China.

Oecologia 2015 Jan 19;177(1):65-72. Epub 2014 Nov 19.

Key Laboratory of Biogeography and Bioresource in Arid Land, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, China.

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http://dx.doi.org/10.1007/s00442-014-3122-4DOI Listing
January 2015

Maintaining glycogen synthase kinase-3 activity is critical for mTOR kinase inhibitors to inhibit cancer cell growth.

Cancer Res 2014 May 13;74(9):2555-68. Epub 2014 Mar 13.

Authors' Affiliations: Departments of Hematology and Medical Oncology and Pathology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029841PMC
May 2014

The PI3 kinase inhibitor NVP-BKM120 induces GSK3/FBXW7-dependent Mcl-1 degradation, contributing to induction of apoptosis and enhancement of TRAIL-induced apoptosis.

Cancer Lett 2013 Sep 2;338(2):229-38. Epub 2013 Apr 2.

Department of Respiration, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, PR China.

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http://dx.doi.org/10.1016/j.canlet.2013.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750077PMC
September 2013

Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.

J Biol Chem 2013 May 27;288(19):13215-24. Epub 2013 Mar 27.

Departments of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://www.jbc.org/content/288/19/13215.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M113.463679
Publisher Site
http://dx.doi.org/10.1074/jbc.M113.463679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650361PMC
May 2013

[Characteristics of evapotranspiration and crop coefficient of agroecosystems in semi-arid area of Loess Plateau, Northwest China].

Ying Yong Sheng Tai Xue Bao 2013 May;24(5):1209-14

Gansu Province Key Laboratory of Arid Climatic Change and Reducing Disaster/China Meteorological Administration Key Open Laboratory of Arid Climatic Change and Disaster Reduction, Institute of Arid Meteorology, China Meteorological Administration, Lanzhou 730020, China.

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May 2013

mTOR complex 2 is involved in regulation of Cbl-dependent c-FLIP degradation and sensitivity of TRAIL-induced apoptosis.

Cancer Res 2013 Mar 14;73(6):1946-57. Epub 2013 Jan 14.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-3710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602308PMC
March 2013

The combination of RAD001 and NVP-BKM120 synergistically inhibits the growth of lung cancer in vitro and in vivo.

Cancer Lett 2012 Dec 7;325(2):139-46. Epub 2012 Jul 7.

Department of Respiration, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Shaanxi, PR China.

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http://dx.doi.org/10.1016/j.canlet.2012.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433638PMC
December 2012

The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition.

Cancer Prev Res (Phila) 2012 Apr 16;5(4):612-20. Epub 2012 Feb 16.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://cancerpreventionresearch.aacrjournals.org/cgi/doi/10.
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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324640PMC
April 2012

Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer.

Cancer Biol Ther 2012 Mar 1;13(5):272-80. Epub 2012 Mar 1.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.

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http://dx.doi.org/10.4161/cbt.18923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679095PMC
March 2012

Development and validation of a test dose strategy for once-daily i.v. busulfan: importance of fixed infusion rate dosing.

Biol Blood Marrow Transplant 2012 Feb 27;18(2):295-301. Epub 2011 Jul 27.

Alberta Blood and Marrow Transplant Program, Foothills Hospital, and Tom Baker Cancer Centre, 1331-29th Street N.W., Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.bbmt.2011.07.015DOI Listing
February 2012

Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling.

J Biol Chem 2012 Jan 7;287(1):257-67. Epub 2011 Nov 7.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1074/jbc.M111.304006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249076PMC
January 2012

The NEDD8-activating enzyme inhibitor, MLN4924, cooperates with TRAIL to augment apoptosis through facilitating c-FLIP degradation in head and neck cancer cells.

Mol Cancer Ther 2011 Dec 13;10(12):2415-25. Epub 2011 Sep 13.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, 1365-C Clifton Road NE, C3088, Atlanta, GA 30322, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-11
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http://dx.doi.org/10.1158/1535-7163.MCT-11-0401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237891PMC
December 2011

The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo.

PLoS One 2011 14;6(6):e20899. Epub 2011 Jun 14.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020899PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114848PMC
October 2011

Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3.

Cancer Res 2011 Oct 25;71(19):6270-81. Epub 2011 Aug 25.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-0838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185138PMC
October 2011

Randomized clinical trial of single-incision versus conventional laparoscopic cholecystectomy: short-term operative outcomes.

Surg Laparosc Endosc Percutan Tech 2011 Oct;21(5):311-3

TianJin Medical University, TianJin NanKai Hospital, TianJin, China.

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http://dx.doi.org/10.1097/SLE.0b013e31822cfacdDOI Listing
October 2011

[Effects of climate warming on oil flax growth and water use efficiency in semi-arid region of Loess Plateau, Northwest China].

Ying Yong Sheng Tai Xue Bao 2011 Oct;22(10):2635-42

Gansu Province Key Laboratory of Arid Climate Change and Reducing Disaster/China Meteorological Administration Key Laboratory of Arid Climate Change and Reducing Disaster, Lanzhou Institute of Arid Meteorology, China Meteorological Administration, Lanzhou 730020, China.

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October 2011

Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy.

Cancer Biol Ther 2011 Sep 15;12(6):549-55. Epub 2011 Sep 15.

Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.

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http://dx.doi.org/10.4161/cbt.12.6.16397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218593PMC
September 2011

Retinoic acid enhances TRAIL-induced apoptosis in cancer cells by upregulating TRAIL receptor 1 expression.

Cancer Res 2011 Aug 17;71(15):5245-54. Epub 2011 Jun 17.

Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151668PMC
August 2011

ERK/ribosomal S6 kinase (RSK) signaling positively regulates death receptor 5 expression through co-activation of CHOP and Elk1.

J Biol Chem 2010 Dec 2;285(53):41310-9. Epub 2010 Nov 2.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1074/jbc.M110.153775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009856PMC
December 2010

c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL.

Mol Cancer 2010 Dec 20;9:315. Epub 2010 Dec 20.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1186/1476-4598-9-315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018404PMC
December 2010

Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.

Neoplasia 2010 Oct;12(10):848-55

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA 30322, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950334PMC
http://dx.doi.org/10.1593/neo.10704DOI Listing
October 2010

Proteasome inhibitor PS-341 (bortezomib) induces calpain-dependent IkappaB(alpha) degradation.

J Biol Chem 2010 May 24;285(21):16096-104. Epub 2010 Mar 24.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia 30322, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.072694
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http://dx.doi.org/10.1074/jbc.M109.072694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871478PMC
May 2010

The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.

Neoplasia 2010 Apr;12(4):346-56

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA 30322, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847742PMC
http://dx.doi.org/10.1593/neo.10144DOI Listing
April 2010

c-FLIP degradation mediates sensitization of pancreatic cancer cells to TRAIL-induced apoptosis by the histone deacetylase inhibitor LBH589.

PLoS One 2010 Apr 28;5(4):e10376. Epub 2010 Apr 28.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010376PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860986PMC
April 2010

Dissecting the roles of DR4, DR5 and c-FLIP in the regulation of geranylgeranyltransferase I inhibition-mediated augmentation of TRAIL-induced apoptosis.

Mol Cancer 2010 Jan 29;9:23. Epub 2010 Jan 29.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, Georgia, USA.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-9-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824632PMC
January 2010

Celecoxib antagonizes perifosine's anticancer activity involving a cyclooxygenase-2-dependent mechanism.

Mol Cancer Ther 2009 Sep 15;8(9):2575-85. Epub 2009 Sep 15.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-09-0390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755226PMC
September 2009

Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy.

Cancer Biol Ther 2008 Dec 8;7(12):1952-8. Epub 2008 Dec 8.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762753PMC
http://dx.doi.org/10.4161/cbt.7.12.6944DOI Listing
December 2008

Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cells.

Mol Cancer Ther 2008 Nov;7(11):3556-65

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, 1365-C Clifton Road Northeast, Atlanta, GA 30322, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-08
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http://dx.doi.org/10.1158/1535-7163.MCT-08-0648DOI Listing
November 2008

Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation.

Cancer Res 2008 Sep;68(18):7409-18

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562339PMC
September 2008

Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activation.

Cancer Res 2008 Sep;68(18):7484-92

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597446PMC
September 2008

CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells.

Cancer Res 2008 Jul;68(13):5335-44

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6209DOI Listing
July 2008

The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.

Mol Cancer Ther 2008 Jul;7(7):2212-23

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-2409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756752PMC
July 2008

c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.

Cancer Biol Ther 2007 Oct 19;6(10):1614-20. Epub 2007 Jul 19.

Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.4161/cbt.6.10.4763DOI Listing
October 2007

The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.

Mol Cancer Ther 2007 Jul 29;6(7):2029-38. Epub 2007 Jun 29.

Winship Cancer Institute, Emory University School of Medicine, 1365-C Clifton Road Northeast, C3088, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0004DOI Listing
July 2007

The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells.

J Biol Chem 2007 Jun 9;282(26):18800-9. Epub 2007 May 9.

Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M611438200
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June 2007

The farnesyltransferase inhibitor R115777 up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer cells.

Cancer Res 2007 May;67(10):4973-80

Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4044DOI Listing
May 2007

PPARgamma ligands enhance TRAIL-induced apoptosis through DR5 upregulation and c-FLIP downregulation in human lung cancer cells.

Cancer Biol Ther 2007 Jan;6(1):99-106

Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.4161/cbt.6.1.3555DOI Listing
January 2007

Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.

Cancer Res 2006 Dec;66(23):11115-9

Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-06-2471DOI Listing
December 2006

A novel DNMT3B subfamily, DeltaDNMT3B, is the predominant form of DNMT3B in non-small cell lung cancer.

Int J Oncol 2006 Jul;29(1):201-7

Molecular Biology Laboratory, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, 77030, USA.

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July 2006

Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).

Cancer Biol Ther 2006 May 2;5(5):492-7. Epub 2006 May 2.

Department of Hematology and Oncology, Winship Cancer Institute, Emory University of School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.4161/cbt.5.5.2565DOI Listing
May 2006

Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells.

Clin Cancer Res 2006 Jan;12(1):273-80

Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0503DOI Listing
January 2006

Decoy receptor 2 (DcR2) is a p53 target gene and regulates chemosensitivity.

Cancer Res 2005 Oct;65(20):9169-75

Department of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0939DOI Listing
October 2005

Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

Cancer Res 2005 Aug;65(16):7052-8

Department of Hematology and Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0917DOI Listing
August 2005

Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4HPR at clinically relevant concentrations.

Cancer Biol Ther 2005 Apr 21;4(4):407-13. Epub 2005 Apr 21.

Department of Thoracic, Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.4161/cbt.4.4.1618DOI Listing
April 2005

Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.

J Natl Cancer Inst 2004 Dec;96(23):1769-80

Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1093/jnci/djh322DOI Listing
December 2004

p53 upregulates death receptor 4 expression through an intronic p53 binding site.

Cancer Res 2004 Aug;64(15):5078-83

Winship Cancer Institute, Emory University School of Medicine, 1365-C Clifton Road, Clinical Building C-3088, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-1195DOI Listing
August 2004

Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 nef in cells of the immune system.

Am J Pathol 2002 Jul;161(1):321-35

Laboratory of Molecular Biology, Clinical Research Institute of Montreal, Montreal, Quebec, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850688PMC
http://dx.doi.org/10.1016/S0002-9440(10)64184-3DOI Listing
July 2002

Effect of AT(1) receptor blockade on cardiac apoptosis in angiotensin II-induced hypertension.

Am J Physiol Heart Circ Physiol 2002 May;282(5):H1635-41

Multidisciplinary Research Group on Hypertension, Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada H2W 1R7.

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http://dx.doi.org/10.1152/ajpheart.00984.2001DOI Listing
May 2002

Evidence that the human death receptor 4 is regulated by activator protein 1.

Oncogene 2002 May;21(20):3121-9

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://www.nature.com/articles/1205430
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http://dx.doi.org/10.1038/sj.onc.1205430DOI Listing
May 2002

The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells.

Cancer Res 2002 Apr;62(8):2430-6

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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April 2002

Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.

Mol Cancer Ther 2002 Jan;1(3):177-84

Department of Thoracic/Head and Neck Medical Oncology, Box 432, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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January 2002