Publications

2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl)acetamides as BACE1 inhibitors: Synthesis, biological evaluation and docking studies.
Eur J Med Chem 2017 Sep 10;137:462-475. Epub 2017 Jun 10.
Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Peking University Health Science Center, 38 Xueyuan Road, Beijing 100191, China. Electronic address:

Ground-to-satellite quantum teleportation.
Nature 2017 Sep 9;549(7670):70-73. Epub 2017 Aug 9.
Department of Modern Physics and Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei 230026, China.

Coupling between d-3-phosphoglycerate dehydrogenase and d-2-hydroxyglutarate dehydrogenase drives bacterial l-serine synthesis.
Proc Natl Acad Sci U S A 2017 Sep 21;114(36):E7574-E7582. Epub 2017 Aug 21.
State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China

Directing enzyme devolution for biosynthesis of alkanols and 1,n-alkanediols from natural polyhydroxy compounds.
Metab Eng 2017 Sep 16. Epub 2017 Sep 16.
State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China; Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, Shanghai 200237, People's Republic of China.

Genetic variants associated with the root system architecture of oilseed rape (Brassica napus L.) under contrasting phosphate supply.
DNA Res 2017 Aug;24(4):407-417
National Key Laboratory of Crop Genetic Improvement and National Centre of Plant Gene Research, Huazhong Agricultural University, Wuhan 430070, China.

Can Non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes?
J Clin Endocrinol Metab 2017 Aug;102(8):2873-2880
Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Miami School of Medicine, Miami, Florida 33136.

Impact of CYP2C19 Genotype and Liver Function on Voriconazole Pharmacokinetics in Renal Transplant Recipients.
Ther Drug Monit 2017 Aug;39(4):422-428
*Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha; †Department of Pharmacy, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai; ‡Department of Urological Organ Transplantation, the Second Xiangya Hospital of Central South University, Changsha; §Beijing Dryas Pharma-Tech Co. Ltd, Beijing, China; and ¶Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.

Drug resistance mutation profiles of the drug-naïve and first-line regimen-treated HIV-1-infected population of Suzhou, China.
Virol Sin 2017 Aug 7;32(4):271-279. Epub 2017 Aug 7.
Research Group of HIV-1 Molecular Epidemiology and Virology, The State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.

Regulation of enterovirus 2A protease-associated viral IRES activities by the cell's ERK signaling cascade: Implicating ERK as an efficiently antiviral target.
Antiviral Res 2017 Jul 27;143:13-21. Epub 2017 Mar 27.
Department of Microbiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China. Electronic address:


A rapid and easy protein N-terminal profiling strategy using (N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide (TMPP) labeling and StageTip.
Proteomics 2017 Jul 3;17(13-14). Epub 2017 Jul 3.
State Key Laboratory of Proteomics, National Center for Protein Sciences Beijing, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, P. R. China.


1,3-Propanediol production by a newly isolated strain, Clostridium perfringens GYL.
Bioresour Technol 2017 Jun 28;233:406-412. Epub 2017 Feb 28.
State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China; Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, Shanghai 200237, People's Republic of China.

Trilocular phenotype in Brassica juncea L. resulted from interruption of CLAVATA1 gene homologue (BjMc1) transcription.
Sci Rep 2017 Jun 14;7(1):3498. Epub 2017 Jun 14.
National Key Laboratory of Crop Genetic Improvement and National Engineering Research Center of Rapeseed, Huazhong Agricultural University, Wuhan, 430070, China.

Pharmacogenetic and case-control study on potassium channel related gene variants and genetic generalized epilepsy.
Medicine (Baltimore) 2017 Jun;96(26):e7321
aDepartment of Pharmacy, the Second Xiangya Hospital, Central South University, Institute of Clinical Pharmacy bDepartment of Neurosurgery, the Third Xiangya Hospital cDepartment of Pathology, the Affiliated Cancer Hospital of Xiangya School of Medicine dDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, P. R. China.

Coordination of metabolic pathways: Enhanced carbon conservation in 1,3-propanediol production by coupling with optically pure lactate biosynthesis.
Metab Eng 2017 May 7;41:102-114. Epub 2017 Apr 7.
State Key Laboratory of Microbial Metabolism, and School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China; Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, Shanghai 200237, People's Republic of China. Electronic address:

Clinical Significance of Dynamics of Programmed Death Ligand-1 Expression on Circulating CD14(+) Monocytes and CD19(+) B Cells with the Progression of Hepatitis B Virus Infection.
Viral Immunol 2017 Apr 22;30(3):224-231. Epub 2016 Dec 22.
1 Department of Biochemistry and Molecular Biology, School of Biology and Basic Medical Sciences, Soochow University , Suzhou, China .


Molecular characterization of a novel ssRNA ourmia-like virus from the rice blast fungus Magnaporthe oryzae.
Arch Virol 2017 Mar 17;162(3):891-895. Epub 2016 Nov 17.
Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA Campus Montegancedo UPM), Pozuelo de Alarcón, 28223, Madrid, Spain.

A genetic variant in long non-coding RNA MALAT1 associated with survival outcome among patients with advanced lung adenocarcinoma: a survival cohort analysis.
BMC Cancer 2017 Mar 3;17(1):167. Epub 2017 Mar 3.
Department of Oncology, Wuhan Iron and Steel (Group) Corporation Staff-Worker Hospital, 32 Qinghua Road, Wuhan, 430085, China.

Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell.
Oxid Med Cell Longev 2017 8;2017:3481710. Epub 2017 Feb 8.
Canada-China-New Zealand Joint Laboratory of Maternal and Fetal Medicine, Chongqing Medical University, Chongqing 400016, China; College of Medicine, University of Leicester, Leicester LE1 7RH, UK.

Hepatitis B Virus X Protein Stimulates Proliferation, Wound Closure and Inhibits Apoptosis of HuH-7 Cells via CDC42.
Int J Mol Sci 2017 Mar 8;18(3). Epub 2017 Mar 8.
State Key Laboratory of Proteomics, Beijing Proteome Research Centre, National Engineering Research Centre for Protein Drugs, National Centre for Protein Sciences Beijing, Institute of Radiation Medicine, Beijing 102206, China.

Cyclophosphamide enhances anti-tumor effects of a fibroblast activation protein α-based DNA vaccine in tumor-bearing mice with murine breast carcinoma.
Immunopharmacol Immunotoxicol 2017 Feb 22;39(1):37-44. Epub 2016 Dec 22.
a National Engineering Laboratory for AIDS Vaccine, School of Life Science , Jilin University , Changchun , P. R. China.

Soluble cpg15 from Astrocytes Ameliorates Neurite Outgrowth Recovery of Hippocampal Neurons after Mouse Cerebral Ischemia.
J Neurosci 2017 Feb 9;37(6):1628-1647. Epub 2017 Jan 9.
Laboratory of Genomic Physiology, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China

Effects of aqueous extracts of Ecliptae herba, Polygoni multiflori radix praeparata and Rehmanniae radix praeparata on melanogenesis and the migration of human melanocytes.
J Ethnopharmacol 2017 Jan 28;195:89-95. Epub 2016 Nov 28.
First Clinical College, Nanjing University of Chinese Medicine, Nanjing 210029, China; Department of Dermatology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210009, China.

Trough concentration and ABCG2 polymorphism are better to predict imatinib response in chronic myeloid leukemia: a meta-analysis.
Pharmacogenomics 2017 Jan 19;18(1):35-56. Epub 2016 Dec 19.
Clinical Pharmacy & Pharmacology Research Institute, the Second Xiangya Hospital, Central South University, 139 Renmin Middle Road, Changsha, Hunan Province 410011, People's Republic of China.

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.
Hum Mol Genet 2017 Jan;26(2):454-465
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

Multi-omics analyses reveal metabolic alterations regulated by hepatitis B virus core protein in hepatocellular carcinoma cells.
Sci Rep 2017 Jan 23;7:41089. Epub 2017 Jan 23.
School of Basic Medical Sciences, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery of Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.

High Pressure-Induced mtDNA Alterations in Retinal Ganglion Cells and Subsequent Apoptosis.
Front Cell Neurosci 2016 24;10:254. Epub 2016 Nov 24.
Eye and ENT Hospital, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan UniversityShanghai, China; Shanghai Key Laboratory of Visual Impairment and RestorationShanghai, China; Key Laboratory of Myopia, Ministry of Health, Fudan UniversityShanghai, China.

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