Pim Toonen

Pim Toonen

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Pim Toonen

Pim Toonen

Publications by authors named "Pim Toonen"

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The Genomic Scrapheap Challenge; Extracting Relevant Data from Unmapped Whole Genome Sequencing Reads, Including Strain Specific Genomic Segments, in Rats.

PLoS One 2016 8;11(8):e0160036. Epub 2016 Aug 8.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160036PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976967PMC
August 2017

Lack of major genome instability in tumors of p53 null rats.

PLoS One 2015 26;10(3):e0122066. Epub 2015 Mar 26.

Hubrecht Institute, KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122066PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374866PMC
March 2016

Large-scale identification of coregulated enhancer networks in the adult human brain.

Cell Rep 2014 Oct 16;9(2):767-79. Epub 2014 Oct 16.

Hubrecht Institute-KNAW & University Medical Center Utrecht, Uppsalalaan 8, 3584CT, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.09.023DOI Listing
October 2014

Olanzapine-induced changes in glucose metabolism are independent of the melanin-concentrating hormone system.

Psychoneuroendocrinology 2013 Nov 13;38(11):2640-6. Epub 2013 Jul 13.

Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, An Institute of the Royal Netherlands Academy of Arts and Science, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2013.06.021DOI Listing
November 2013

Melanocortin receptor 4 deficiency affects body weight regulation, grooming behavior, and substrate preference in the rat.

Obesity (Silver Spring) 2012 Mar 28;20(3):612-21. Epub 2011 Apr 28.

Hubrecht Institute-KNAW & University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/oby.2011.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286758PMC
March 2012

Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency.

Am J Pathol 2011 Oct 18;179(4):1616-22. Epub 2011 Aug 18.

Hubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, KNAW and University Medical Center Utrecht, Utrecht, The Netherlands.

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http://www.criver.com/about-us/eureka/wp-content/uploads/ACT
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http://transposagenbio.com/pdf/p53-TGEN-Am-J-Path-2011.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000294401100657
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http://dx.doi.org/10.1016/j.ajpath.2011.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181367PMC
October 2011

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples.

Nat Methods 2010 Nov 17;7(11):913-5. Epub 2010 Oct 17.

Hubrecht Institute, Developmental Biology and Stem Cell Research, Royal Netherlands Academy of Arts and Sciences and the University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nmeth.1516DOI Listing
November 2010

Pmch expression during early development is critical for normal energy homeostasis.

Am J Physiol Endocrinol Metab 2010 Mar 24;298(3):E477-88. Epub 2009 Nov 24.

Hubrecht Institute-Koninklijke Nederlandse Akademie van Wetenschappen and University Medical Center Utrecht, The Netherlands.

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http://dx.doi.org/10.1152/ajpendo.00154.2009DOI Listing
March 2010

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

BMC Genomics 2008 Oct 7;9:460. Epub 2008 Oct 7.

Hubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, Royal Netherlands Academy of Sciences, Utrecht, The Netherlands.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-9-460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567347PMC
October 2008

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.

Carcinogenesis 2008 Jun 15;29(6):1290-7. Epub 2008 Apr 15.

Hubrecht Institute for Developmental Biology and Stem Cell Research, Cancer Genomics Center, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/carcin/bgn094DOI Listing
June 2008