Pietro Alano

Pietro Alano

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Pietro Alano

Publications by authors named "Pietro Alano"

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Critical Steps of Ookinete Maturation.

Front Microbiol 2020 17;11:269. Epub 2020 Mar 17.

Vector Biology, Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.3389/fmicb.2020.00269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092720PMC
March 2020

Antimalarial activity of primaquine operates via a two-step biochemical relay.

Nat Commun 2019 07 19;10(1):3226. Epub 2019 Jul 19.

Centre for Drugs and Diagnostics Research, Tropical Disease Biology Department, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.

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http://dx.doi.org/10.1038/s41467-019-11239-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642103PMC
July 2019

The emerging role of the human bone marrow as a privileged developmental niche for the transmission stages of the malaria parasite Plasmodium falciparum. Commentary.

Authors:
Pietro Alano

Ann Ist Super Sanita 2017 Apr-Jun;53(2):96-99

Dipartimento di Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.4415/ANN_17_02_03DOI Listing
April 2018

Ned-19 inhibition of parasite growth and multiplication suggests a role for NAADP mediated signalling in the asexual development of Plasmodium falciparum.

Malar J 2017 09 12;16(1):366. Epub 2017 Sep 12.

Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Section of Histology and Medical Embryology, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.1186/s12936-017-2013-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596470PMC
September 2017

Comparative Proteomics and Functional Analysis Reveal a Role of Plasmodium falciparum Osmiophilic Bodies in Malaria Parasite Transmission.

Mol Cell Proteomics 2016 10 18;15(10):3243-3255. Epub 2016 Jul 18.

From the ‡Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena n.299, 00161 Roma, Italy;

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http://dx.doi.org/10.1074/mcp.M116.060681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054347PMC
October 2016

Discovering New Transmission-Blocking Antimalarial Compounds: Challenges and Opportunities.

Trends Parasitol 2016 09 18;32(9):669-681. Epub 2016 May 18.

Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2016.04.017DOI Listing
September 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

A chemical susceptibility profile of the Plasmodium falciparum transmission stages by complementary cell-based gametocyte assays.

J Antimicrob Chemother 2016 May 16;71(5):1148-58. Epub 2016 Feb 16.

Dipartimento di Malattie Infettive, Parassitarie, Immunomediate, Istituto Superiore di Sanità, Rome, Italy

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http://dx.doi.org/10.1093/jac/dkv493DOI Listing
May 2016

A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds.

Sci Rep 2015 Nov 10;5:16414. Epub 2015 Nov 10.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena n. 299, 00161 Roma, Italy.

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http://dx.doi.org/10.1038/srep16414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639769PMC
November 2015

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage.

Malar J 2015 Aug 28;14:334. Epub 2015 Aug 28.

Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

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http://dx.doi.org/10.1186/s12936-015-0853-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552133PMC
August 2015

Erythrocyte remodeling by Plasmodium falciparum gametocytes in the human host interplay.

Trends Parasitol 2015 Jun 27;31(6):270-8. Epub 2015 Mar 27.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena n.299, 00161 Rome, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714922150004
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http://dx.doi.org/10.1016/j.pt.2015.02.006DOI Listing
June 2015

Enlightening the malaria parasite life cycle: bioluminescent Plasmodium in fundamental and applied research.

Front Microbiol 2015 11;6:391. Epub 2015 May 11.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità Rome, Italy.

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http://dx.doi.org/10.3389/fmicb.2015.00391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426725PMC
June 2015

Bone marrow reticulocytes: a Plasmodium vivax affair?

Blood 2015 Feb;125(8):1203-5

ISTITUTO SUPERIORE DI SANITÀ

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http://dx.doi.org/10.1182/blood-2014-12-614123DOI Listing
February 2015

The sound of sexual commitment breaks the silencing of malaria parasites.

Authors:
Pietro Alano

Trends Parasitol 2014 Nov 25;30(11):509-10. Epub 2014 Sep 25.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, viale Regina Elena n.299, 00161 Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2014.09.002DOI Listing
November 2014

A fast, non-invasive, quantitative staining protocol provides insights in Plasmodium falciparum gamete egress and in the role of osmiophilic bodies.

Malar J 2014 Oct 1;13:389. Epub 2014 Oct 1.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena n,299, 00161 Roma, Italy.

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http://malariajournal.biomedcentral.com/articles/10.1186/147
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http://dx.doi.org/10.1186/1475-2875-13-389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194377PMC
October 2014

Feeling at home from arrival to departure: protein export and host cell remodelling during Plasmodium liver stage and gametocyte maturation.

Cell Microbiol 2014 Mar 24;16(3):324-33. Epub 2014 Jan 24.

Max Planck Institute for Infection Biology, Parasitology Unit, 10117, Berlin, Germany.

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http://dx.doi.org/10.1111/cmi.12251DOI Listing
March 2014

Uncovering the hideout of malaria sexual parasites.

Blood 2014 Feb;123(7):954-5

INSTITUT COCHIN;

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http://dx.doi.org/10.1182/blood-2013-12-545418DOI Listing
February 2014

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection.

J Antimicrob Chemother 2013 Sep 3;68(9):2048-58. Epub 2013 May 3.

Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, 20133 Milan, Italy.

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http://dx.doi.org/10.1093/jac/dkt165DOI Listing
September 2013

Early gametocytes of the malaria parasite Plasmodium falciparum specifically remodel the adhesive properties of infected erythrocyte surface.

Cell Microbiol 2013 Apr 21;15(4):647-59. Epub 2012 Nov 21.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, viale Regina Elena 299, 00161, Rome, Italy.

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http://dx.doi.org/10.1111/cmi.12062DOI Listing
April 2013

The Plasmodium falciparum schizont phosphoproteome reveals extensive phosphatidylinositol and cAMP-protein kinase A signaling.

J Proteome Res 2012 Nov 18;11(11):5323-37. Epub 2012 Oct 18.

Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1021/pr300557mDOI Listing
November 2012

Specific tagging of the egress-related osmiophilic bodies in the gametocytes of Plasmodium falciparum.

Malar J 2012 Mar 27;11:88. Epub 2012 Mar 27.

Infectious Diseases Department, Istituto Superiore di Sanità, v.le Regina Elena 299, Rome 00161, Italy.

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http://dx.doi.org/10.1186/1475-2875-11-88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342164PMC
March 2012

Protein export marks the early phase of gametocytogenesis of the human malaria parasite Plasmodium falciparum.

Mol Cell Proteomics 2010 Jul 22;9(7):1437-48. Epub 2010 Mar 22.

double daggerDipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1074/mcp.M900479-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938084PMC
July 2010

Regulated oligomerisation and molecular interactions of the early gametocyte protein Pfg27 in Plasmodium falciparum sexual differentiation.

Int J Parasitol 2010 May 5;40(6):663-73. Epub 2009 Dec 5.

Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena n.299, 00161 Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S002075190900422
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http://dx.doi.org/10.1016/j.ijpara.2009.11.006DOI Listing
May 2010

Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction.

BMC Genomics 2009 Sep 21;10:445. Epub 2009 Sep 21.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Roma, Italy.

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http://dx.doi.org/10.1186/1471-2164-10-445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756283PMC
September 2009

The Plasmodium falciparum protein Pfg27 is dispensable for gametocyte and gamete production, but contributes to cell integrity during gametocytogenesis.

Mol Microbiol 2009 Jul 30;73(2):180-93. Epub 2009 Jun 30.

Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, 00161, Rome, Italy.

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http://dx.doi.org/10.1111/j.1365-2958.2009.06762.xDOI Listing
July 2009

A 140-bp AT-rich sequence mediates positive and negative transcriptional control of a Plasmodium falciparum developmentally regulated promoter.

Int J Parasitol 2008 Mar 29;38(3-4):299-312. Epub 2007 Sep 29.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Rome, Italy.

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http://dx.doi.org/10.1016/j.ijpara.2007.08.014DOI Listing
March 2008

Plasmodium falciparum regulatory subunit of cAMP-dependent PKA and anion channel conductance.

PLoS Pathog 2008 Feb;4(2):e19

INSERM U609, Wellcome Center for Molecular Parasitology, Glasgow Biomedical Research Centre, Glasgow, Scotland, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.0040019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222956PMC
February 2008

Plasmodium falciparum gametocytes: still many secrets of a hidden life.

Authors:
Pietro Alano

Mol Microbiol 2007 Oct 3;66(2):291-302. Epub 2007 Sep 3.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena n. 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1111/j.1365-2958.2007.05904.xDOI Listing
October 2007

Plasmodium falciparum: mRNA co-expression and protein co-localisation of two gene products upregulated in early gametocytes.

Exp Parasitol 2007 Aug 8;116(4):497-503. Epub 2007 Feb 8.

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena n.299, 00161 Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S001448940700038
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http://dx.doi.org/10.1016/j.exppara.2007.01.021DOI Listing
August 2007

Functional genomics, new tools in malaria research.

Ann Ist Super Sanita 2005 ;41(4):469-77

Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, Istituto Superiore di Sanità, Rome, Italy.

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August 2006

Genome-wide identification of genes upregulated at the onset of gametocytogenesis in Plasmodium falciparum.

Mol Biochem Parasitol 2005 Sep;143(1):100-10

Dipartimento di Malattie Infettive Parassitarie e Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S016668510500175
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http://dx.doi.org/10.1016/j.molbiopara.2005.04.015DOI Listing
September 2005

Biochemical characterization of the two nucleosome assembly proteins from Plasmodium falciparum.

Mol Biochem Parasitol 2005 Aug;142(2):237-47

Structural Biology Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.

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http://linkinghub.elsevier.com/retrieve/pii/S016668510500136
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http://dx.doi.org/10.1016/j.molbiopara.2005.04.006DOI Listing
August 2005

Identification and initial characterization of three novel cyclin-related proteins of the human malaria parasite Plasmodium falciparum.

J Biol Chem 2003 Oct 17;278(41):39839-50. Epub 2003 Jul 17.

INSERM U511 team, Wellcome Centre for Molecular Parasitology, Anderson College, 56 Dumbarton Road, Glasgow G11 6NU, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M301625200DOI Listing
October 2003

A gene-family encoding small exported proteins is conserved across Plasmodium genus.

Mol Biochem Parasitol 2003 Feb;126(2):209-18

Laboratorio di Biologia Cellulare, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

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http://dx.doi.org/10.1016/s0166-6851(02)00275-xDOI Listing
February 2003