Pieter H Reitsma

Pieter H Reitsma

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Pieter H Reitsma

Publications by authors named "Pieter H Reitsma"

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Use of "C9/11 Mismatch" Control siRNA Reveals Sequence-Related Off-Target Effect on Coagulation of an siRNA Targeting Mouse Coagulation Factor XII.

Nucleic Acid Ther 2019 Aug 7;29(4):218-223. Epub 2019 May 7.

1Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1089/nat.2018.0767DOI Listing
August 2019

Blood coagulation factor Va's key interactive residues and regions for prothrombinase assembly and prothrombin binding.

J Thromb Haemost 2019 Aug 17;17(8):1229-1239. Epub 2019 Jun 17.

Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/jth.14487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851895PMC
August 2019

Elevated coagulation factor levels affect the tissue factor-threshold in thrombin generation.

Thromb Res 2018 12 25;172:104-109. Epub 2018 Oct 25.

Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.10.020DOI Listing
December 2018

Pulmonary embolism.

Nat Rev Dis Primers 2018 05 17;4:18028. Epub 2018 May 17.

Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.1038/nrdp.2018.28DOI Listing
May 2018

Factor V levels and risk of venous thrombosis: The MEGA case-control study.

Res Pract Thromb Haemost 2018 Apr 14;2(2):320-326. Epub 2018 Apr 14.

Department of Thrombosis and Haemostasis Leiden University Medical Center Leiden The Netherlands.

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http://doi.wiley.com/10.1002/rth2.12091
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http://dx.doi.org/10.1002/rth2.12091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055494PMC
April 2018

Multi-dose drug dispensing as a tool to improve medication adherence: A study in patients using vitamin K antagonists.

Pharmacoepidemiol Drug Saf 2018 01 6;27(1):46-51. Epub 2017 Nov 6.

Department of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/pds.4346DOI Listing
January 2018

Engineered factor Xa variants retain procoagulant activity independent of direct factor Xa inhibitors.

Nat Commun 2017 09 13;8(1):528. Epub 2017 Sep 13.

Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41467-017-00647-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597622PMC
September 2017

Genetic variation in the first-pass metabolism of ethinylestradiol, sex hormone binding globulin levels and venous thrombosis risk.

Eur J Intern Med 2017 Jul 1;42:54-60. Epub 2017 Jun 1.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2017.05.019DOI Listing
July 2017

Silencing of Anticoagulant Protein C Evokes Low-Incident but Spontaneous Atherothrombosis in Apolipoprotein E-Deficient Mice-Brief Report.

Arterioscler Thromb Vasc Biol 2017 05 16;37(5):782-785. Epub 2017 Mar 16.

From the Division of Biopharmaceutics, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, The Netherlands (A.B.O., R.A.F.V., M.v.E.); Einthoven Laboratory for Experimental Vascular Medicine (M.H., P.H.R., B.J.M.v.V.), and Department of Internal Medicine, Division of Thrombosis and Hemostasis (M.H., P.H.R., B.J.M.v.V.), Leiden University Medical Center, The Netherlands; Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, The Netherlands (M.J.J.G.); and Department of Medical Biochemistry, The Academic Medical Center, Amsterdam, The Netherlands (M.J.J.G.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309188DOI Listing
May 2017

Reduced acute myocardial ischemia-reperfusion injury in IL-6-deficient mice employing a closed-chest model.

Inflamm Res 2016 Jun 2;65(6):489-99. Epub 2016 Mar 2.

Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anesthesiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00011-016-0931-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841857PMC
June 2016

Circulating nucleosomes and elastase α1-antitrypsin complexes and the novel thrombosis susceptibility locus SLC44A2.

Thromb Res 2016 Jun 13;142:8-10. Epub 2016 Apr 13.

Einthoven Laboratory for Experimental Vascular Medicine, Division of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, The Netherlands; Department of Internal Medicine, Division of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2016.04.005DOI Listing
June 2016

Tissue factor associates with survival and regulates tumour progression in osteosarcoma.

Thromb Haemost 2016 05 14;115(5):1025-33. Epub 2016 Jan 14.

Henri H. Versteeg, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands, Tel.: +31 715263872, Fax: +31 71526755, E-mail:

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http://dx.doi.org/10.1160/TH15-07-0541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428546PMC
May 2016

The immediate and late effects of thyroid hormone (triiodothyronine) on murine coagulation gene transcription.

PLoS One 2015 26;10(5):e0127469. Epub 2015 May 26.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127469PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444115PMC
April 2016

Changes in Dietary Fat Content Rapidly Alters the Mouse Plasma Coagulation Profile without Affecting Relative Transcript Levels of Coagulation Factors.

PLoS One 2015 15;10(7):e0131859. Epub 2015 Jul 15.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131859PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503443PMC
April 2016

Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome).

Thromb Res 2015 Sep;136 Suppl 1:S3-7

Leiden University Medical Centre, Department of Thrombosis and Hemostasis, Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.thromres.2015.07.034DOI Listing
September 2015

Genetic variations associated with recurrent venous thrombosis.

Circ Cardiovasc Genet 2014 Dec 10;7(6):806-13. Epub 2014 Sep 10.

From the Department of Clinical Epidemiology (A.v.H.V., L.E.F., S.C.C., F.R.R.), Department of Thrombosis and Haemostasis (P.H.R., F.R.R.), and Einthoven Laboratory for Experimental Vascular Medicine (A.v.H.V., S.C.C., P.H.R., F.R.R.), Leiden University Medical Center, Leiden, the Netherlands; and Celera, Alameda, CA (L.A.B., A.R.A., C.H.T., J.J.D.).

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000682DOI Listing
December 2014

Storage and secretion of naturally occurring von Willebrand factor A domain variants.

Br J Haematol 2014 Nov 8;167(4):529-40. Epub 2014 Aug 8.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/bjh.13074DOI Listing
November 2014

Regulation of the F11, Klkb1, Cyp4v3 gene cluster in livers of metabolically challenged mice.

PLoS One 2013 16;8(9):e74637. Epub 2013 Sep 16.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands ; Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074637PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774739PMC
May 2014

Major Haemorrhage during Vitamin K Antagonist Treatment: The Influence of Thyroid Hormone Levels.

Eur Thyroid J 2014 Mar 28;3(1):32-7. Epub 2014 Feb 28.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, Amsterdam, The Netherlands ; Department of Endocrinology and Metabolism, Leiden University Medical Centre, Leiden, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000357578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005261PMC
March 2014

Suspected survivor bias in case-control studies: stratify on survival time and use a negative control.

J Clin Epidemiol 2014 Feb 17;67(2):232-5. Epub 2013 Aug 17.

Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jclinepi.2013.05.011DOI Listing
February 2014

Alternatively spliced tissue factor promotes breast cancer growth in a β1 integrin-dependent manner.

Proc Natl Acad Sci U S A 2013 Jul 25;110(28):11517-22. Epub 2013 Jun 25.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1073/pnas.1307100110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710867PMC
July 2013

Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production.

Blood 2013 May 2;121(21):4413-6. Epub 2013 Apr 2.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1182/blood-2012-11-465674DOI Listing
May 2013

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.

Blood 2013 Apr 20;121(14):2762-72. Epub 2013 Feb 20.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1182/blood-2012-06-434373DOI Listing
April 2013

Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide.

Haematologica 2013 Jan 16;98(1):153-8. Epub 2012 Jul 16.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2012.069997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533678PMC
January 2013

New fundamentals in hemostasis.

Physiol Rev 2013 Jan;93(1):327-58

Einthoven Laboratroy for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1152/physrev.00016.2011DOI Listing
January 2013

Modulation of mouse coagulation gene transcription following acute in vivo delivery of synthetic small interfering RNAs targeting HNF4α and C/EBPα.

PLoS One 2012 1;7(6):e38104. Epub 2012 Jun 1.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038104PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365905PMC
October 2012

Multiple SNP testing improves risk prediction of first venous thrombosis.

Blood 2012 Jul 14;120(3):656-63. Epub 2012 May 14.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-12-397752DOI Listing
July 2012

Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation.

Haematologica 2012 Jun 29;97(6):859-66. Epub 2011 Dec 29.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.3324/haematol.2011.057216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366651PMC
June 2012

Mechanistic view of risk factors for venous thromboembolism.

Arterioscler Thromb Vasc Biol 2012 Mar;32(3):563-8

Department of Thrombosis and Hemostasis, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.111.242818
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http://dx.doi.org/10.1161/ATVBAHA.111.242818DOI Listing
March 2012

The relationship between tissue factor and cancer progression: insights from bench and bedside.

Blood 2012 Jan 7;119(4):924-32. Epub 2011 Nov 7.

Department of Thrombosis and Hemostasis, Einthoven Laboratory for Experimental Vascular Medicine, Leiden Univerisity Medical Center, Leiden, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-06-31
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http://dx.doi.org/10.1182/blood-2011-06-317685DOI Listing
January 2012

Intracellular storage and regulated secretion of von Willebrand factor in quantitative von Willebrand disease.

J Biol Chem 2011 Jul 19;286(27):24180-8. Epub 2011 May 19.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M110.215194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129199PMC
July 2011

PTX3 predicts severe disease in febrile patients at the emergency department.

J Infect 2010 Feb 2;60(2):122-7. Epub 2009 Dec 2.

Department of Internal Medicine, Slotervaart Hospital, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jinf.2009.11.010DOI Listing
February 2010

Updated analysis of gene variants associated with deep vein thrombosis.

JAMA 2010 Feb;303(5):421-2

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1001/jama.2010.57DOI Listing
February 2010

Gross deletions/duplications in PROS1 are relatively common in point mutation-negative hereditary protein S deficiency.

Hum Genet 2009 Sep 23;126(3):449-56. Epub 2009 May 23.

Einthoven Laboratory for Experimental Vascular Medicine, C2-143, Department of Thrombosis and Haemostasis, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00439-009-0687-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774415PMC
September 2009

How to identify new genetic risk factors for VTE?

Authors:
Pieter H Reitsma

Thromb Res 2009 ;123 Suppl 4:S22-4

Department of Thrombosis and Hemostasis, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1016/S0049-3848(09)70138-0DOI Listing
July 2009

Coagulation factor Xa inhibits cancer cell migration via protease-activated receptor-1 activation.

Thromb Res 2009 Jun 27;124(2):219-25. Epub 2009 Feb 27.

Department of Cell Biology, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.thromres.2009.01.015DOI Listing
June 2009

F9 Malmö, factor IX and deep vein thrombosis.

Haematologica 2009 May 13;94(5):693-9. Epub 2009 Mar 13.

Department of Clinical Epidemiology, C7-P Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.3324/haematol.2008.003020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675682PMC
May 2009

Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung.

Clin Exp Metastasis 2009 10;26(3):171-8. Epub 2008 Dec 10.

Department of Medical Oncology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10585-008-9227-6DOI Listing
April 2009

Assessment of coagulation and fibrinolysis in families with unexplained thrombophilia.

Thromb Haemost 2009 Mar;101(3):465-70

Dept. of Vascular Medicine, F4-276, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

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March 2009

Polymorphisms in the protein C gene as risk factor for venous thrombosis.

Thromb Haemost 2009 Jan;101(1):62-7

Department of Clinical Epidemiology, C9-P, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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January 2009

Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders.

J Cell Mol Med 2008 Dec 20;12(6B):2622-7. Epub 2008 Mar 20.

Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1582-4934.2008.00316.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828878PMC
December 2008

PROS1 analysis in 87 pedigrees with hereditary protein S deficiency demonstrates striking genotype-phenotype associations.

Hum Mutat 2008 Jul;29(7):939-47

Department of Haematology, Division of Haemostasis, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/humu.20687DOI Listing
July 2008

VKORC1 and the vitamin K cycle.

Vitam Horm 2008 ;78:23-33

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/S0083-6729(07)00002-7DOI Listing
April 2008

Gene variants associated with deep vein thrombosis.

JAMA 2008 Mar;299(11):1306-14

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1001/jama.299.11.1306DOI Listing
March 2008

Factor Xa stimulates proinflammatory and profibrotic responses in fibroblasts via protease-activated receptor-2 activation.

Am J Pathol 2008 Feb 17;172(2):309-20. Epub 2008 Jan 17.

Center for Experimental and Molecular Medicine, Academic Medical Center, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2353/ajpath.2008.070347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312363PMC
February 2008

Protease-activated receptor-4 inhibition protects from multiorgan failure in a murine model of systemic inflammation.

Blood 2007 Nov 19;110(9):3176-82. Epub 2007 Jul 19.

Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibregdreef 9, 1105 AZ Amsterdam, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2007-02-07
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http://dx.doi.org/10.1182/blood-2007-02-075440DOI Listing
November 2007

Hyperglycemia accelerates arterial thrombus formation and attenuates the antithrombotic response to endotoxin in mice.

Blood Coagul Fibrinolysis 2007 Oct;18(7):627-36

Laboratory for Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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https://insights.ovid.com/crossref?an=00001721-200710000-000
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http://dx.doi.org/10.1097/MBC.0b013e3282891ebdDOI Listing
October 2007

Gene expression profiling identifies C/EBPdelta as a candidate regulator of endotoxin-induced disseminated intravascular coagulation.

Am J Respir Crit Care Med 2007 Sep 28;176(6):602-9. Epub 2007 Jun 28.

Center for Experimental and Molecular Medicine, G2-132, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200609-1250O
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http://dx.doi.org/10.1164/rccm.200609-1250OCDOI Listing
September 2007

Transgenic mouse models of venous thrombosis: fulfilling the expectations?

Semin Thromb Hemost 2007 Sep;33(6):610-6

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1055/s-2007-985758DOI Listing
September 2007

Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation.

Exp Cell Res 2007 Jul 19;313(12):2622-33. Epub 2007 Apr 19.

Center for Experimental and Molecular Medicine, Academic Medical Center, Meibergdreef 9, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.yexcr.2007.04.014DOI Listing
July 2007

The effect of homocysteine reduction by B-vitamin supplementation on inflammatory markers.

Clin Chem Lab Med 2007 ;45(1):54-8

Department of Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1515/CCLM.2007.021DOI Listing
March 2007

Role of the factor V Leiden mutation in septic peritonitis assessed in factor V Leiden transgenic mice.

Crit Care Med 2006 Aug;34(8):2201-6

Laboratory for Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/01.CCM.0000228918.30931.E8DOI Listing
August 2006

Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia.

Crit Care Med 2006 Jun;34(6):1725-30

Center of Infection and Immunity Amsterdam, Laboratory of Experimental Internal Medicine, Department of Pulmonology, University of Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/01.CCM.0000218807.20570.C2DOI Listing
June 2006

Renal tissue factor expression is increased in streptozotocin-induced diabetic mice.

Nephron Exp Nephrol 2005 30;101(3):e86-94. Epub 2005 Jun 30.

Laboratory for Experimental Internal Medicine, AMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000086646DOI Listing
April 2006

Differential expression of tissue factor mRNA and protein expression in murine sepsis. The role of the granulocyte revisited.

Thromb Haemost 2006 Feb;95(2):348-53

Department of Internal Medicine, University Maastricht, P.O. Box 616, UNS50/Box 8, 6200 MD Maastricht, The Netherlands.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH05-07-0512
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http://dx.doi.org/10.1160/TH05-07-0512DOI Listing
February 2006

Blood coagulation factors as inflammatory mediators.

Blood Cells Mol Dis 2005 Jan-Feb;34(1):30-7

Laboratory for Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bcmd.2004.09.001DOI Listing
December 2005

Plasma cytokine and P-selectin levels in advanced malignancy: prognostic value and impact of low-molecular weight heparin administration.

Cancer 2005 Nov;104(10):2275-81

Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/cncr.21485DOI Listing
November 2005

A C1173T dimorphism in the VKORC1 gene determines coumarin sensitivity and bleeding risk.

PLoS Med 2005 Oct 11;2(10):e312. Epub 2005 Oct 11.

Laboratory for Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pmed.0020312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1251635PMC
October 2005

Low molecular weight heparin attenuates multiple organ failure in a murine model of disseminated intravascular coagulation.

Crit Care Med 2005 Jun;33(6):1365-70

Laboratory for Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://pdfs.journals.lww.com/ccmjournal/2005/06000/Low_molec
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http://dx.doi.org/10.1097/01.ccm.0000166370.94927.b6DOI Listing
June 2005

High throughput mRNA profiling highlights associations between myocardial infarction and aberrant expression of inflammatory molecules in blood cells.

Blood 2005 Mar 2;105(5):2000-6. Epub 2004 Nov 2.

Laboratory for Experimental Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.

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http://dx.doi.org/10.1182/blood-2004-08-3283DOI Listing
March 2005

Blood cell-derived tissue factor influences host response during murine endotoxemia.

Blood Cells Mol Dis 2004 Mar-Apr;32(2):325-33

Laboratory for Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bcmd.2003.12.002DOI Listing
October 2004

Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice.

Gastroenterology 2004 Aug;127(2):535-45

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2004.04.017DOI Listing
August 2004

Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice.

J Infect Dis 2004 Jun 25;189(12):2308-17. Epub 2004 May 25.

Laboratory of Experimental Internal Medicine and Department of Infectious Diseases, Tropical Medicine, and AIDS, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1086/421031DOI Listing
June 2004

Anti-inflammatory and anticoagulant effects of pravastatin in patients with type 2 diabetes.

Diabetes Care 2004 Feb;27(2):468-73

Laboratory for Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, and Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2337/diacare.27.2.468DOI Listing
February 2004

Genomics and proteomics: implications for inflammatory bowel diseases.

Inflamm Bowel Dis 2004 Feb;10 Suppl 1:S1-6

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/00054725-200402001-00001DOI Listing
February 2004