Piers Blombery

Cat-Scratch Disease Masquerading as C3 Glomerulonephritis.

Authors:

Benjamin Sutu Shio Yen Tio Lucy C Fox Joseph Sasadeusz Piers Blombery Moira J Finlay Thomas D Barbour

Kidney Int Rep 2020 Dec 3;5(12):2388-2392. Epub 2020 Oct 3.

Department of Nephrology, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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December 2020

Laboratory quality assessment of candidate gene panel testing for acute myeloid leukaemia: a joint ALLG / RCPAQAP initiative.

Authors:

Greg Corboy Jad Othman Linda Lee Andrew Wei Adam Ivey Piers Blombery Rishu Agarwal Chun Fong Anna Brown Hamish Scott Carolyn Grove Alison Louw Anoop Enjeti Harry Iland Cheryl Paul Stefan Bohlander Purvi Kakadia Martin Horan William Stevenson

Pathology 2020 Nov 30. Epub 2020 Nov 30.

Australasian Leukaemia and Lymphoma Group (ALLG), Richmond, Vic, Australia; Department of Haematology, Royal North Shore Hospital, St Leonards, NSW, Australia; Molecular Haematology, NSW Health Pathology, Royal North Shore Hospital, St Leonards, NSW, Australia.

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November 2020

Immune recovery in patients with mantle cell lymphoma receiving long-term ibrutinib and venetoclax combination therapy.

Authors:

Joanne E Davis Sasanka M Handunnetti Mandy Ludford-Menting Chia Sharpe Piers Blombery Mary Ann Anderson Andrew W Roberts John F Seymour Constantine S Tam David S Ritchie Rachel M Koldej

Blood Adv 2020 Oct;4(19):4849-4859

ACRF Translational Research Laboratory, Royal Melbourne Hospital, Melbourne, VIC, Australia.

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October 2020

Clonal independence of and or mutations in comutated myeloproliferative neoplasms demonstrated by single cell DNA sequencing.

Authors:

Ella R Thompson Tamia Nguyen Yamuna Kankanige Paul Yeh Michael Ingbritsen Michelle McBean Timothy Semple Gisela Mir Arnau Kate Burbury Nora Lee Amit Khot David Westerman Piers Blombery

Haematologica 2021 01 1;106(1):313-315. Epub 2021 Jan 1.

Pathology, Oncology and Clinical Haematology, Peter MacCallum Cancer Centre, Melbourne.

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January 2021

Inotuzumab ozogamicin resistance associated with a novel CD22 truncating mutation in a case of B-acute lymphoblastic leukaemia.

Authors:

Georgina L Ryland Allison Barraclough Chun Yew Fong Shaun Fleming Ashish Bajel Oliver Hofmann David Westerman Sean Grimmond Piers Blombery

Br J Haematol 2020 Oct 9;191(1):123-126. Epub 2020 Jul 9.

Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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October 2020

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot.

Authors:

Simon P Keam Heloise Halse Thu Nguyen Minyu Wang Nicolas Van Kooten Losio Catherine Mitchell Franco Caramia David J Byrne Sue Haupt Georgina Ryland Phillip K Darcy Shahneen Sandhu Piers Blombery Ygal Haupt Scott G Williams Paul J Neeson

J Immunother Cancer 2020 06;8(1)

Cancer Immunology Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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June 2020

Publisher Correction: CNspector: a web-based tool for visualisation and clinical diagnosis of copy number variation from next generation sequencing.

Authors:

John F Markham Satwica Yerneni Georgina L Ryland Huei San Leong Andrew Fellowes Ella R Thompson Wasanthi De Silva Amit Kumar Richard Lupat Jason Li Jason Ellul Stephen Fox Michael Dickinson Anthony T Papenfuss Piers Blombery

Sci Rep 2020 Jun 23;10(1):10400. Epub 2020 Jun 23.

Department of Pathology, Peter MacCallum Cancer Centre, Parkville, VIC, Australia.

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June 2020

A synonymous GATA2 variant underlying familial myeloid malignancy with striking intrafamilial phenotypic variability.

Authors:

Lucy C Fox Michelle Tan Anna L Brown Peer Arts Ella Thompson Georgina L Ryland Jennifer Lickiss Hamish S Scott Nicola K Poplawski Kerry Phillips Neil A Came Paul James Stephen B Ting David S Ritchie Jeff Szer Christopher N Hahn Anthony Schwarer Piers Blombery

Br J Haematol 2020 Sep 3;190(5):e297-e301. Epub 2020 Jun 3.

Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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September 2020

Recovery of natural killer cell cytotoxicity in a p.A91V perforin homozygous patient following severe haemophagocytic lymphohistiocytosis.

Authors:

Helena S Jang Thijs W H Flinsenberg Paul Lacaze Kevin Y T Thia Tahereh Noori Suran L Fernando Ian Kerridge Moeen Riaz John J McNeil Piers A Blombery Joseph A Trapani Ilia Voskoboinik

Br J Haematol 2020 08 27;190(3):458-461. Epub 2020 Apr 27.

Cancer Immunology Program, Killer Cell Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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August 2020

Detection of an IGH- fusion in a patient with BRAF Val600Glu negative hairy cell leukemia.

Authors:

Ella R Thompson Kenneth J C Lim James A Kuzich Michelle McBean David Westerman Constantine S Tam Piers Blombery

Leuk Lymphoma 2020 08 22;61(8):2024-2026. Epub 2020 Apr 22.

Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Australia.

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August 2020

BTK inhibitor therapy is effective in patients with CLL resistant to venetoclax.

Authors:

Victor S Lin Thomas E Lew Sasanka M Handunnetti Piers Blombery Tamia Nguyen David A Westerman Bryone J Kuss Constantine S Tam Andrew W Roberts John F Seymour Mary Ann Anderson

Blood 2020 06;135(25):2266-2270

Department of Clinical Haematology, Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

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June 2020

Diagnostic evaluation and considerations in hypocellular bone marrow failure-A focus on genomics.

Authors:

Lucy C Fox Erica M Wood David S Ritchie Piers Blombery

Int J Lab Hematol 2020 Jun 5;42 Suppl 1:82-89. Epub 2020 Mar 5.

Peter MacCallum Cancer Centre, Melbourne, Vic., Australia.

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June 2020

Utility of clinical comprehensive genomic characterization for diagnostic categorization in patients presenting with hypocellular bone marrow failure syndromes.

Haematologica 2021 01 1;106(1):64-73. Epub 2021 Jan 1.

Clinical Haematology, Peter MacCallum Cancer Centre/Royal Melbourne Hospital, Melbourne, Australia.

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January 2021

Multiple BCL2 mutations cooccurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax.

Authors:

Piers Blombery Ella R Thompson Tamia Nguyen Richard W Birkinshaw Jia-Nan Gong Xiangting Chen Michelle McBean Rachel Thijssen Thomas Conway Mary Ann Anderson John F Seymour David A Westerman Peter E Czabotar David C S Huang Andrew W Roberts

Blood 2020 03;135(10):773-777

Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Parkville, VIC, Australia.

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March 2020

Severe chemotherapy toxicity in a 10-year-old with T-acute lymphoblastic lymphoma harboring biallelic variants.

Authors:

Georgina L Ryland Lucy C Fox Virginia Wootton Ella R Thompson Jennifer Lickiss Alison H Trainer Paddy Barbaro Morag Whyte David Ritchie Piers Blombery

Leuk Lymphoma 2020 05 16;61(5):1257-1259. Epub 2020 Jan 16.

Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Australia.

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May 2020

Undetectable peripheral blood MRD should be the goal of venetoclax in CLL, but attainment plateaus after 24 months.

Authors:

Thomas E Lew Mary Ann Anderson Victor S Lin Sasanka M Handunnetti Neil A Came Piers Blombery David A Westerman Meaghan Wall Constantine S Tam Andrew W Roberts John F Seymour

Blood Adv 2020 01;4(1):165-173

Department of Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Parkville, Australia.

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January 2020

Rapid and Durable Complete Remission of Refractory AITL with Azacitidine Treatment in Absence of TET2 Mutation or Concurrent MDS.

Authors:

Gareth P Gregory Michael Dickinson Costas K Yannakou Jonathan Wong Piers Blombery Greg Corboy Lev Kats Tim M E Crozier Beena Kumar H Miles Prince Stephen S Opat Jake Shortt

Hemasphere 2019 Apr 1;3(2):e187. Epub 2019 Mar 1.

Monash Health, Clayton, Victoria, Australia.

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April 2019

Mechanisms of intrinsic and acquired resistance to venetoclax in B-cell lymphoproliferative disease.

Authors:

Piers Blombery

Leuk Lymphoma 2020 02 18;61(2):257-262. Epub 2019 Sep 18.

Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Australia.

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February 2020

Characterization of a novel venetoclax resistance mutation (BCL2 Phe104Ile) observed in follicular lymphoma.

Authors:

Piers Blombery Richard W Birkinshaw Tamia Nguyen Jia-Nan Gong Ella R Thompson Zhen Xu David A Westerman Peter E Czabotar Michael Dickinson David C S Huang John F Seymour Andrew W Roberts

Br J Haematol 2019 09 24;186(6):e188-e191. Epub 2019 Jun 24.

Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Australia.

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September 2019

Characteristics and outcomes of therapy-related myeloid neoplasms after peptide receptor radionuclide/chemoradionuclide therapy (PRRT/PRCRT) for metastatic neuroendocrine neoplasia: a single-institution series.

Authors:

Isaac Goncalves Kate Burbury Michael Michael Amir Iravani Aravind S Ravi Kumar Tim Akhurst Ing S Tiong Piers Blombery Michael S Hofman David Westerman Rodney J Hicks Grace Kong

Eur J Nucl Med Mol Imaging 2019 Aug 11;46(9):1902-1910. Epub 2019 Jun 11.

Nuclear Medicine Department, Peter MacCallum Cancer Centre, Melbourne, Australia.

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August 2019

Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.

Authors:

Richard W Birkinshaw Jia-Nan Gong Cindy S Luo Daisy Lio Christine A White Mary Ann Anderson Piers Blombery Guillaume Lessene Ian J Majewski Rachel Thijssen Andrew W Roberts David C S Huang Peter M Colman Peter E Czabotar

Nat Commun 2019 06 3;10(1):2385. Epub 2019 Jun 3.

Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia.

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June 2019

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study.

Authors:

Amit Khot Natalie Brajanovski Donald P Cameron Nadine Hein Kylee H Maclachlan Elaine Sanij John Lim John Soong Emma Link Piers Blombery Ella R Thompson Andrew Fellowes Karen E Sheppard Grant A McArthur Richard B Pearson Ross D Hannan Gretchen Poortinga Simon J Harrison

Cancer Discov 2019 08 15;9(8):1036-1049. Epub 2019 May 15.

Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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August 2019

CNspector: a web-based tool for visualisation and clinical diagnosis of copy number variation from next generation sequencing.

Authors:

John F Markham Satwica Yerneni Georgina L Ryland Huei San Leong Andrew Fellowes Ella R Thompson Wasanthi De Silva Amit Kumar Richard Lupat Jason Li Jason Ellul Stephen Fox Michael Dickinson Anthony T Papenfuss Piers Blombery

Sci Rep 2019 04 23;9(1):6426. Epub 2019 Apr 23.

Department of Pathology, Peter MacCallum Cancer Centre, Parkville, VIC, Australia.

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April 2019

Molecular Drivers of Breast Implant-Associated Anaplastic Large Cell Lymphoma.

Authors:

Piers Blombery Ella R Thompson H Miles Prince

Plast Reconstr Surg 2019 03;143(3S A Review of Breast Implant-Associated Anaplastic Large Cell Lymphoma):59S-64S

From the Department of Pathology, Peter MacCalllum Cancer Centre, and the Sir Peter MacCallum Department of Oncology, University of Melbourne; and Molecular Oncology and Cancer Immunology, Epworth Healthcare.

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March 2019