Pierre-Yves Michellys

Pierre-Yves Michellys

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Pierre-Yves Michellys

Pierre-Yves Michellys

Publications by authors named "Pierre-Yves Michellys"

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22Publications

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Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.

ACS Med Chem Lett 2019 Jun 23;10(6):887-892. Epub 2019 May 23.

Global Discovery Chemistry, and Autoimmunity Transplantation Inflammation, Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1021/acsmedchemlett.9b00044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580379PMC
June 2019

Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.

Bioorg Med Chem Lett 2016 Feb 17;26(3):1090-1096. Epub 2015 Nov 17.

Novartis Institutes for BioMedical Research, Inc., 250 Massachusetts Avenue, Cambridge, MA 02139, United States.

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http://dx.doi.org/10.1016/j.bmcl.2015.11.049DOI Listing
February 2016

Novel tricyclic pyrazolopyrimidines as potent and selective GPR119 agonists.

Bioorg Med Chem Lett 2014 Dec 13;24(23):5478-83. Epub 2014 Oct 13.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.10.010DOI Listing
December 2014

Syk inhibitors with high potency in presence of blood.

Bioorg Med Chem Lett 2014 May 3;24(10):2278-82. Epub 2014 Apr 3.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2014.03.075DOI Listing
May 2014

Discovery of structurally novel, potent and orally efficacious GPR119 agonists.

Bioorg Med Chem Lett 2014 May 27;24(10):2383-7. Epub 2014 Mar 27.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.03.023DOI Listing
May 2014

Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.

Biochem J 2010 Sep;430(3):425-37

The Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1042/BJ20100609DOI Listing
September 2010

Conjugate hydrocyanation of 17-acetyl-11-carbomethoxygona-1,3,5(10),13(17)-tetraenes.

Steroids 2007 Mar 4;72(3):297-304. Epub 2007 Jan 4.

UMR 6180 CNRS and Université d'Aix Marseille III: Chirotechnologies: catalyse et biocatalyse, Laboratoire de Synthèse Organique associé au CNRS, Avenue Escadrille Normandie Niémen, 13397 Marseille Cedex 20, France.

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http://dx.doi.org/10.1016/j.steroids.2006.11.022DOI Listing
March 2007

Design, synthesis and structure-activity relationship of novel RXR-selective modulators.

Bioorg Med Chem Lett 2004 Mar;14(6):1593-8

Department of Medicinal Chemistry, Ligand Pharmaceuticals Incorporated, 10275 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.bmcl.2003.12.089DOI Listing
March 2004